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Delfien Bogaert

61 Resultaten

2022

Familial hemophagocytic lymphohistiocytosis type 3 presenting as neonatal cholestasis and splenomegaly

Delfien BogaertRuth De BruyneArnaud VanlanderFilomeen HaerynckBarbara De Moerloose

A1 Artikel in een tijdschrift in PEDIATRIC ALLERGY AND IMMUNOLOGY

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Leslie NaesensJosephine NemegeerDelfien BogaertKatrien StaesVeronique DebackerPieter De BleserMarieke De BruyneElfride De BaereBart LambrechtJens StaalTessa KerreRudi BeyaertJonathan MaelfaitSimon TavernierFilomeen Haerynck

A1 Artikel in een tijdschrift in SCIENCE IMMUNOLOGY

How to recognize inborn errors of immunity in a child presenting with a malignancy : guidelines for the pediatric hemato-oncologist

Charlotte DerpoorterDelfien Bogaert

A1 Artikel in een tijdschrift in PEDIATRIC HEMATOLOGY AND ONCOLOGY

2021

GTF3A mutations in a patient with herpes simplex encephalitis reveals a novel role in viral immunity by transcribing 5S rRNA pseudogenes serving as RIG-I ligands

Leslie NaesensJosephine NemegeerDelfien BogaertJens StaalKatrien StaesVeronique DebackerMarieke De BruyneBart LambrechtRudi BeyaertTessa KerreSimon TavernierJonathan MaelfaitFilomeen Haerynck

Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort

Levi HosteJarno De CraemerDelfien BogaertCarolien BonroyJan PhilippéJulie WillekensTessa KerreFilomeen Haerynck

Paediatrician in Training Discussion Panel 1 : the challenges of tele-paediatrics : a lockdown-inspired clinical grand round

Eline HermansDelfien BogaertLien DosscheLevi Hoste

2020

Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19

Karel Van DammeSimon TavernierNele Van RoyElisabeth De LeeuwJozefien DeclercqCédric BosteelsBastiaan MaesMarieke De BruyneDelfien BogaertVictor BosteelsLevi HosteLeslie NaesensPieter DepuydtEva Van BraeckelFilomeen HaerynckBart Lambrecht

A1 Artikel in een tijdschrift in FRONTIERS IN IMMUNOLOGY

Expect the unexpected : clinical case

Delfien BogaertMarieke De BruyneElfride De BaereFilomeen Haerynck

GATA2 deficiency and haematopoietic stem cell transplantation : challenges for the clinical practitioner

Delfien BogaertGenevieve LaureysLeslie NaesensMarieke De BruyneVictoria Bordon MariaSimon TavernierBart LambrechtElfride De BaereFilomeen HaerynckTessa Kerre

A1 Artikel in een tijdschrift in BRITISH JOURNAL OF HAEMATOLOGY

Hematopoietic stem cell transplantation in children with primary immunodeficiencies : a Belgian single center experience

Delfien BogaertCatharina DhoogeFilomeen HaerynckVictoria Bordon Maria

Severe phototoxicity associated with concomitant use of methotrexate and voriconazole, an overlooked drug-drug interaction

Delfien BogaertEls VandecruysGenevieve LaureysEvelien VerhaegheTieneke Bauters

A1 Artikel in een tijdschrift in PEDIATRIC BLOOD & CANCER

2019

'Every sweet has its sour' : rare skin lesions in a boy with combined immunodeficiency

Delfien BogaertMarieke De BruyneHilde LapeereElfride De BaereFrans De BaetsFilomeen Haerynck

A computational pipeline for the diagnosis of CVID patients

Annelies EmmaneelDelfien BogaertSofie Van GassenSimon TavernierFilomeen HaerynckYvan Saeys

A1 Artikel in een tijdschrift in FRONTIERS IN IMMUNOLOGY

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

Simon TavernierJens StaalDelfien BogaertLeslie NaesensMarieke De BruyneSofie Van GassenEef ParthoensHanne Van GorpGert Van IsterdaelYvan SaeysMohamed LamkanfiPetra SchelstraeteJo DehoorneVictoria Bordon MariaRudy Van CosterBart LambrechtBjörn MentenRudi BeyaertMelissa DullaersFilomeen Haerynck

A1 Artikel in een tijdschrift in NATURE COMMUNICATIONS

Congenital myeloperoxidase deficiency caused by a homozygous MPO splice site mutation in a patient with recurrent candida otomastoiditis

Frederic AckeDelfien BogaertHelen Van HoeckeKatrien BonteCarolien BonroyPetra SchelstraeteMarieke De BruyneElfride De BaereIngeborg DhoogeFilomeen Haerynck

GATA2 deficiency and hematopoietic stem cell transplantation : challenges for the clinical practitioner

Delfien BogaertLeslie NaesensGenevieve LaureysVictoria Bordon MariaSimon TavernierBart LambrechtFilomeen HaerynckTessa Kerre

Immune dysregulation with lymphoproliferation progressing to a rare T-cell non-hodgkin lymphoma

Leslie NaesensHilde DemuynckDelfien BogaertCarolien BonroyFilomeen HaerynckTessa Kerre

Immunoglobulin g subclass and specific polysaccharide antibody deficiency : a clinical and immunological profile in a tertiary cohort

Levi HosteJarno De CraemerDelfien BogaertCarolien BonroyJan PhilippéJulie WillekensTessa KerreFilomeen Haerynck

Rare skin lesions in a boy with activated phosphoinositide 3-kinase delta syndrome

Delfien BogaertMarieke De BruyneHilde LapeereElfride De BaereFrans De BaetsFilomeen Haerynck

2018

A CARD9 founder mutation disrupts NF-κB signaling by inhibiting BCL10 and MALT1 recruitment and signalosome formation

Marieke De BruyneLevi HosteDelfien BogaertSimon TavernierEef ParthoensBart LambrechtSabine Van daeleAna Alves de MedeirosLieve BrochezRudi BeyaertElfride De BaereSavvas SavvidesFilomeen HaerynckJens StaalMelissa Dullaers

A1 Artikel in een tijdschrift in FRONTIERS IN IMMUNOLOGY

A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects

Delfien BogaertCarolien BonroyJo DehoorneArnaud VanlanderMarieke De BruyneFrans De BaetsElfride De BaereFilomeen HaerynckMelissa Dullaers

A1 Artikel in een tijdschrift in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A novel LPS-responsive beige-like anchor protein (LRBA) mutation presents with normal cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and overactive TH17 immunity

Marieke De BruyneDelfien BogaertKoen VenkenCarolien BonroyLisa RoelsSimon TavernierDirk ElewautFilomeen HaerynckMelissa Dullaers

A1 Artikel in een tijdschrift in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ikaros family zinc finger 1 regulates dendritic cell development and function in humans

Delfien BogaertMelissa DullaersFilomeen Haerynck

A1 Artikel in een tijdschrift in NATURE COMMUNICATIONS

Ikaros family zinc finger 1 regulates dendritic cell development and function in humans

Delfien BogaertMelissa DullaersFilomeen Haerynck

Molecular diagnosis of Common Variable Immunodeficiency and related antibody disorders : an integrated immunological and genetic approach

Delfien Bogaert

Redactioneel materiaal

Molecular diagnosis of patients with antibody deficiency

Delfien Bogaert

Primary antibody deficiencies from bedside to bench : the role of molecular diagnostics

Delfien Bogaert

Zuigeling met aseptische meningo-encefalitis gecompliceerd door een brachiale plexusneuritis

Delfien BogaertHelene VerhelstRuth Van der Looven

2017

A CARD9 Turkisch founder mutation disrupts NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneLevi HosteDelfien BogaertBart LambrechtRudi BeyaertElfride De BaereFilomeen HaerynckJens StaalMelissa Dullaers

A CARD9 founder mutation p.Arg70Trp in Belgian and French patients of Turkish origin with a spectrum of chronic mucocutaneous and invasive fungal infections

Marieke De BruyneDelfien BogaertLevi HosteElfride De BaereFilomeen HaerynckMelissa Dullaers

CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneDelfien BogaertLevi HosteBart LambrechtRudi BeyaertElfride De BaereFilomeen HaerynckJens StaalMelissa Dullaers

CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneDelfien BogaertLevi HosteBart LambrechtRudi BeyaertElfride De BaereFilomeen HaerynckJens StaalMelissa Dullaers

CARD9 p.R70W, a Turkish founder mutation associated with mucosal and invasive fungal infections, disrupts downstream NF-κB signaling by inhibiting Bcl10 recruitment

Marieke De BruyneLevi HosteDelfien BogaertBart LambrechtRudi BeyaertElfride De BaereFilomeen HaerynckJens StaalMelissa Dullaers

Early-onset primary antibody deficiency resembling common variable immunodeficiency challenges the diagnosis of Wiedeman-Steiner and Roifman syndromes

Delfien BogaertMelissa DullaersBart LeroyMarieke De BruyneFrauke CoppietersBart LambrechtFrans De BaetsElfride De BaereFilomeen Haerynck

A1 Artikel in een tijdschrift in SCIENTIFIC REPORTS

Molecular diagnosis of Common Variable Immunodeficiency and related antibody disorders : an integrated immunological and genetic approach

Delfien BogaertElfride De BaereFilomeen HaerynckMelissa Dullaers

Molecular genetics of common variable immunodeficiency

Delfien BogaertMelissa DullaersElfride De BaereFilomeen Haerynck

Hoofdstuk in een boek in eLS

The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéVictoria Bordon MariaBart LambrechtTessa KerreKarim VermaelenFilomeen HaerynckMelissa Dullaers

A1 Artikel in een tijdschrift in HAEMATOLOGICA

The immunophenotypical fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives

Delfien BogaertMarieke De BruyneVeronique DebackerPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéVictoria Bordon MariaBart LambrechtTessa KerreAndrea CeruttiKarim VermaelenFilomeen HaerynckMelissa Dullaers

To B or not to B matured : a novel IKAROS haploinsufficiency kindred with incomplete penetrance both at clinical and cellular level

Delfien BogaertCarolien BonroyJo DehoorneArnaud VanlanderMarieke De BruynePetra SchelstraeteFrans De BaetsElfride De BaereFilomeen HaerynckMelissa Dullaers

To B or not to B matured : a novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B cell maturation defects

Delfien BogaertCarolien BonroyJo DehoorneArnaud VanlanderPetra SchelstraeteMarieke De BruyneFrans De BaetsElfride De BaereFilomeen HaerynckMelissa Dullaers

2016

CVID, isolated IgG deficiency and isolated IgG subclass deficiency : clinical features and B cell maturation of the Ghent cohort

Delfien BogaertTessa KerreVictoria Bordon MariaBart LambrechtKarim VermaelenFrans De BaetsElfride De BaereMelissa DullaersFilomeen Haerynck

Chronic and invasive fungal infections in a family with CARD9 deficiency

Ana Alves de MedeirosDelfien BogaertFilomeen HaerynckSabine Van daeleBart LambrechtJo LambertLieve BrochezMelissa Dullaers

A1 Artikel in een tijdschrift in JOURNAL OF CLINICAL IMMUNOLOGY

Chronic and invasive fungal infections in a family with CARD9 deficiency (vol 36, pg 204, 2016)

Delfien BogaertFilomeen HaerynckSabine Van daeleBart LambrechtJo LambertLieve BrochezMelissa Dullaers

Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

Hanne Van GorpPedro Henrique Viana SaavedraNathalia Moraes de VasconcelosNina Van OpdenboschLieselotte Vande WalleMagdalena MatusiakFilip Van HauwermeirenDieter DemonDelfien BogaertMelissa DullaersElfride De BaereTino HochepiedJo DehoorneKarim VermaelenFilomeen HaerynckMohamed Lamkanfi

A1 Artikel in een tijdschrift in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genes associated with common variable immunodeficiency: one diagnosis to rule them all?

Delfien BogaertMelissa DullaersBart LambrechtKarim VermaelenElfride De BaereFilomeen Haerynck

A1 Artikel in een tijdschrift in JOURNAL OF MEDICAL GENETICS

Inflammasomes in inflammatory disease

Hanne Van GorpPedro Henrique Viana SaavedraNathalia Moraes de VasconcelosNina Van OpdenboschLieselotte Vande WalleMagdalena MatusiakFilip Van HauwermeirenDelfien BogaertMelissa DullaersElfride De BaereJo DehoorneKarim VermaelenFilomeen HaerynckMohamed Lamkanfi

JAK2 deficiency as a novel cause of impaired Th17 immunity

Delfien BogaertElfride De BaereKristof Van SchilFrauke CoppietersMarieke De BruyneTessa KerreFrans De BaetsVictoria Bordon MariaKarim VermaelenJan TavernierBart LambrechtSarah GerloMelissa Dullaers

Persistent rotavirus diarrhea post-transplant in a novel JAK3-SCID patient after vaccination

Delfien BogaertKristof Van SchilTom TaghonVictoria Bordon MariaCarolien BonroyMelissa DullaersElfride De BaereFilomeen Haerynck

A1 Artikel in een tijdschrift in PEDIATRIC ALLERGY AND IMMUNOLOGY

RC3H1 mutation with increased ICOS expression causes an autoinflammatory syndrome

Delfien BogaertJoél SmetArnaud VanlanderVictoria Bordon MariaHelene VerhelstRudy Van CosterBjörn MentenMelissa Dullaers

Recurrent cutaneous abscesses as the presenting manifestation of STAT1 gain-of-function mutation

Levi HosteMarieke De BruyneDelfien BogaertElfride De BaereCarolien BonroyPetra SchelstraeteMelissa DullaersFilomeen Haerynck

The immunophenotypical landscape of patients with primary antibody deficiencies and their asymptomatic first-degree relatives : arguments for a multifactorial aetiology

Delfien BogaertPauline DepuydtKatleen De PreterCarolien BonroyJan PhilippéVictoria Bordon MariaTessa KerreBart LambrechtAndrea CeruttiKarim VermaelenElfride De BaereFilomeen HaerynckMelissa Dullaers

2015

A novel Janus kinase 3 (JAK3) mutation in a patient with severe combined immunodeficiency

Delfien BogaertKristof Van SchilTom TaghonVictoria Bordon MariaMelissa DullaersElfride De BaereFilomeen Haerynck

A novel STAT1 mutation in a patient with pneumocystis jiroveci and chronic mucocutaneous candidiasis

Delfien BogaertMelissa DullaersJens StaalSarah GerloElien VandermarliereVictoria Bordon MariaFrans De BaetsBart LambrechtKarim VermaelenFilomeen Haerynck

Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells

Ruth De BruyneDelfien BogaertNatalie De RuyckBart LambrechtMyriam Van WinckelPhilippe GevaertMelissa Dullaers

A1 Artikel in een tijdschrift in CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immunological characterization of pediatric liver transplant associated food allergy

Ruth De BruynePhilippe GevaertMyriam Van WinckelNatalie De RuyckDelfien BogaertStephanie Van BiervlietSaskia Vande VeldeBart LambrechtMelissa DullaersXavier Rogiers

Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in paediatric liver transplant patients

Ruth De BruynePhilippe GevaertMyriam Van WinckelNatalie De RuyckDelfien BogaertStephanie Van BiervlietSaskia Vande VeldeBart LambrechtMelissa Dullaers

A1 Artikel in een tijdschrift in CLINICAL AND EXPERIMENTAL ALLERGY

Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in pediatric liver transplant patients

Ruth De BruyneMyriam Van WinckelPhilippe GevaertNatalie De RuyckDelfien BogaertBart LambrechtMelissa Dullaers

2014

A case of isolated cerebral nocardiosis caused by a defect in the IL12-IFNG axis

Delfien BogaertVeronique DebackerSteven CallensMelissa DullaersKarim Vermaelen

Acquired partial lipodystrophy : a rare clinical presentation of a complement deficiency

Delfien BogaertMelissa DullaersJohan Vande WalleFilomeen Haerynck

Clinical presentation of hyper-IgE syndrome in a family with impaired IL-22 production and STAT3 phosphorylation

Filomeen HaerynckDelfien BogaertElfride De BaereBart LambrechtKarim VermaelenVeronique DebackerKristof Van SchilFrans De BaetsPetra SchelstraeteVictoria Bordon MariaMelissa Dullaers

Use of an integrative classification system and next-generation sequencing strategies for gene identification in common variable immunodeficiency disorder (CVID)

Delfien BogaertMelissa DullaersFilomeen HaerynckElfride De BaereKarim Vermaelen