Research Explorer

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Researcher

Cliff Van Waesberghe

Awards & Distinctions

18 Results

2025

Pseudorabies virus infection triggers pUL46-mediated phosphorylation of connexin-43 and closure of gap junctions to promote intercellular virus spread

Alexander Tishchenko KhoruzhNicolás Romero RataCliff Van WaesbergheJonas L. DelvaOliver VickmanGregory A. SmithThomas C. MettenleiterWalter FuchsBarbara G. KluppHerman Favoreel

U Journal Article in PLOS Pathogens

The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression

Ruth VerhammeRobert JansensJianheng LiuFien Van RaemdonckCliff Van WaesbergheLuke NicholsonSamie R. JaffreyHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

2024

Deletion of gE in herpes simplex virus 1 leads to increased extracellular virus production and augmented interferon alpha production by peripheral blood mononuclear cells

Manon ClaeysJonas DelvaCedric JacqmotteCliff Van WaesbergheHerman Favoreel

A1 Journal Article in PATHOGENS

2023

On-slide lambda protein phosphatase-mediated dephosphorylation of fixed samples

Alexander Tishchenko KhoruzhCliff Van WaesbergheHerman Favoreel

A2 Journal Article in METHODS AND PROTOCOLS

Several Alphaherpesviruses interact similarly with the NF-κB pathway and suppress NF-κB-dependent gene expression

Nicolás Romero RataAlexander Tishchenko KhoruzhRuth VerhammeShelly M. M. Wuerzberger-DavisCliff Van WaesbergheHans NauwynckShigeki MiyamotoHerman Favoreel

A1 Journal Article in MICROBIOLOGY SPECTRUM

2022

Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex

Robert JansensRuth VerhammeAashiq H. MirzaAnthony Olarerin-GeorgeCliff Van WaesbergheSamie R. JaffreyHerman Favoreel

A1 Journal Article in CELL REPORTS

Proteomic comparison of three wild-type pseudorabies virus strains and the attenuated bartha strain reveals reduced incorporation of several tegument proteins in bartha virions

Jonas DelvaSimon DaledCliff Van WaesbergheRuben AlmeyRobert J. J. JansensDieter DeforceMaarten DhaenensHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

Pseudorabies virus infection results in a broad inhibition of host gene transcription

Nicolás Romero RataShelly M. Wuerzberger-DavisCliff Van WaesbergheRobert J. JansensAlexander Tishchenko KhoruzhRuth VerhammeShigeki MiyamotoHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Yue YinJinglin MaCliff Van WaesbergheBert DevriendtHerman Favoreel

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

The attenuated pseudorabies virus vaccine strain Bartha hyperactivates plasmacytoid dendritic cells by generating large amounts of cell-free virus in infected epithelial cells

Jonas DelvaCliff Van WaesbergheWim Van Den BroeckJochen LamoteNick VereeckeSebastiaan TheunsLiesbeth CouckHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

2021

Alphaherpesvirus-induced activation of plasmacytoid dendritic cells depends on the viral glycoprotein gD and is inhibited by non-infectious light particles

Jonas DelvaCliff Van WaesbergheBarbara G. KluppThomas C. MettenleiterHerman Favoreel

A1 Journal Article in PLOS PATHOGENS

Pseudorabies virus infection causes downregulation of Ligands for the activating NK cell receptor NKG2D

Sofie DenaeghelSteffi De PelsmaekerCliff Van WaesbergheHerman Favoreel

A1 Journal Article in VIRUSES-BASEL

2020

Pseudorabies virus infection of epithelial cells leads to persistent but aberrant activation of the NF-kappa B pathway, inhibiting hallmark NF-kappa B-induced proinflammatory gene expression

Nicolás Romero RataCliff Van WaesbergheHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

2017

Pseudorabies virus US3-induced tunneling nanotubes contain stabilized microtubules, interact with neighboring cells via cadherins, and allow intercellular molecular communication

Robert JansensWim Van Den BroeckSteffi De PelsmaekerJochen LamoteCliff Van WaesbergheLiesbeth CouckHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

The pseudorabies virus glycoprotein gE/gI complex suppresses type I interferon production by plasmacytoid dendritic cells

Jochen LamoteManon KestensCliff Van WaesbergheJonas DelvaSteffi De PelsmaekerBert DevriendtHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

2016

Pseudorabies virus glycoprotein gE triggers ERK1/2 phosphorylation and degradation of the pro-apoptotic protein Bim in epithelial cells

Maria Setas Lopes PontesCliff Van WaesbergheHans NauwynckBruno VerhasseltHerman Favoreel

A1 Journal Article in VIRUS RESEARCH

2015

Pseudorabies virus US3 leads to filamentous actin disassembly and contributes to viral genome delivery to the nucleus

Thary JacobCeline Van den BroekeKorneel GrauwetKim BaertChristophe ClaessenSteffi De PelsmaekerCliff Van WaesbergheHerman Favoreel

A1 Journal Article in VETERINARY MICROBIOLOGY

Pseudorabies virus US3 triggers RhoA phosphorylation to reorganize the actin cytoskeleton

Thary JacobCeline Van den BroekeCliff Van WaesbergheMarleen Van TroysHerman Favoreel

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY