Research Explorer

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Researcher

Christine Labeur

Awards & Distinctions

38 Results

2007

Combination of COFRADIC and high temperature - extended column length conventional liquid chromatography: A very efficient way to tackle complex protein samples, such as serum

K SANDRAK VERLEYSENChristine LabeurL VANNESTEF D'HONDTG THOMASKoen KasKris GevaertJoël VandekerckhoveP SANDRA

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

2004

Expression and activity of the nucleotide-binding domains of the human ABCA1 transporter

Stein RoosbeekH CASTERQZ LIUPF BERNEN DUVERGERBart ChristiaensJoël VandekerckhoveFrank PeelmanChristine LabeurMaryvonne Rosseneu

A1 Journal Article in PROTEIN EXPRESSION AND PURIFICATION

Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter

Stein RoosbeekFrank PeelmanAnnick VerheeChristine LabeurH CASTERMarc LensinkC CIRULLIJohan GrootenC COCHETJoël Vandekerckhove et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2003

Characterization of the ABCA transporter subfamily: Identification of prokaryotic and eukaryotic members, phylogeny and topology

Frank PeelmanChristine LabeurBerlinda VanlooStein RoosbeekC DEVAUDN DUVERGERP DENEFLEM ROSIERJoël VandekerckhoveMaryvonne Rosseneu

A1 Journal Article in JOURNAL OF MOLECULAR BIOLOGY

2001

A hydrophobic cluster at the surface of the human plasma phospholipid transfer protein is critical for activity on high density lipoproteins.

C DESRUMAUXChristine LabeurA VERHEEJan TavernierJoël VandekerckhoveMaryvonne RosseneuFrank Peelman

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides.

Nathalie DemeesterC MERTENSH CASTERM GOETHALSJoël VandekerckhoveMaryvonne RosseneuChristine Labeur

A1 Journal Article in EUROPEAN JOURNAL OF NEUROSCIENCE

Effect of mutations of N- and C-terminal charged residues on the activity of LCAT.

Frank PeelmanBerlinda VanlooJean-Luc VerscheldeChristine LabeurH CASTERJ TAVEIRNEA VERHEEN DUVERGERJoël VandekerckhoveJan Tavernier et al.

A1 Journal Article in JOURNAL OF LIPID RESEARCH

2000

Apoptosis induced in neuronal cells by C-terminal amyloid beta-fragments is correlated with their aggregation properties in phospholipid membranes.

N DEMEESTERG BAIERC ENZINGERM GOETHALSJoël VandekerckhoveMaryvonne RosseneuChristine Labeur

A1 Journal Article in MOLECULAR MEMBRANE BIOLOGY

Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin: cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease.

Nathalie DemeesterG CastroC DesrumauxC De GeitereJC FruchartPatrick SantensE MullenersS EngelborghsPP De DeynJoël Vandekerckhove et al.

A1 Journal Article in JOURNAL OF LIPID RESEARCH

Characterization of recombinant wild type and site-directed mutations of apolipoprotein C-III: Lipid binding, displacement of ApoE, and inhibition of lipoprotein lipase.

HQ LIUPJ TALMUDL LINSR BRASSEURG OLIVECRONAFrank PeelmanJoël VandekerckhoveMaryvonne RosseneuChristine Labeur

A1 Journal Article in BIOCHEMISTRY

Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr.

HQ LIUChristine LabeurCF XUR FERRELLL LINSR BRASSEURMaryvonne RosseneuKM WEISSSE HUMPHRIESPJ TALMUD

A1 Journal Article in JOURNAL OF LIPID RESEARCH

Experimental gerontology in Belgium: from model organisms to age-related pathologies.

O TOUSSAINTPV BARETJP BRIONP CRASF COLLETTEPP DE DEYNV GEENENP KIENLEN-CAMPARDChristine LabeurJJ LEGROS et al.

A1 Journal Article in EXPERIMENTAL GERONTOLOGY

Headgroup specificity of lecithin cholesterol acyltransferase for monomeric and vesicular phospholipids.

Bart ChristiaensBerlinda VanlooC GOUYETTEInge Van VyncktH CASTERJ TAVEIRNEA VERHEEChristine LabeurFrank PeelmanJoël Vandekerckhove et al.

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Relationship between structure and biochemical phenotype of lecithin: cholesterol acyltransferase (LCAT) mutants causing fish-eye disease.

Berlinda VanlooFrank PeelmanKristof DeschuymereJ TAVEIRNEA VERHEEC GOUYETTEChristine LabeurJoël VandekerckhoveJan TavernierMaryvonne Rosseneu

A1 Journal Article in JOURNAL OF LIPID RESEARCH

1999

Characterisation of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase.

Berlinda VanlooFrank PeelmanChristine LabeurJoël VandekerckhoveJan TavernierMaryvonne Rosseneu

Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT).

Frank PeelmanB VANLOOO PEREZ-MENDEZA DECOUTJL VERSCHELDEChristine LabeurN VINAIMONTA VERHEEN DUVERGERR BRASSEUR et al.

A1 Journal Article in PROTEIN ENGINEERING

Contribution of the hydrophobicity gradient to the secondary structure and activity of fusogenic peptides.

Anne DecoutChristine LabeurBerlinda VanlooM GOETHALSJoël VandekerckhoveR BRASSEURMaryvonne Rosseneu

A1 Journal Article in MOLECULAR MEMBRANE BIOLOGY

Effects of natural mutations in lecithin:cholesterol acyltransferase on the enzyme structure and activity

Frank PeelmanJean-Luc VerscheldeBerlinda VanlooChristophe AmpeChristine LabeurJan TavernierJoël VandekerckhoveMaryvonne Rosseneu

A1 Journal Article in JOURNAL OF LIPID RESEARCH

LCAT defects and low HDL levels.

Maryvonne RosseneuFrank PeelmanJL VERSCHELDEB VANLOOChristine LabeurJan TavernierJoël Vandekerckhove

A1 Journal Article in ATHEROSCLEROSIS

Lipids, apolipoproteins and LCAT in cerebrospinal fluid of normal individuals and patients with Alzhelmer's disease

Christine LabeurP SANTENSN DEMEESTERKelly TillemanJoël VandekerckhoveMaryvonne Rosseneu

The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: Involvement of its C-terminal fusogenic domain.

T PILLOTB DROUETS QUEILLEChristine LabeurJoël VandekerckhoveMaryvonne RosseneuM PINCON-RAYMONDJ CHAMBAZ

A1 Journal Article in JOURNAL OF NEUROCHEMISTRY

beta-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: Relevance to Alzheimer's disease.

T PILLOTM GOETHALSJ NAJIBChristine LabeurL LINSJ CHAMBAZR BRASSEURJoël VandekerckhoveMaryvonne Rosseneu

A1 Journal Article in JOURNAL OF NEUROCHEMISTRY

1998

A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling.

Frank PeelmanN VINAIMONTA VERHEEB VANLOOJL VERSCHELDEChristine LabeurS SEGURET-MACEN DUVERGERG HUTCHINSONJoël Vandekerckhove et al.

A1 Journal Article in PROTEIN SCIENCE

Comparison of three fatty meals in healthy normolipidaemic men: high post-prandial retinyl ester response to soybean oil.

N MEROM SYVANNEMaryvonne RosseneuChristine LabeurH HILDENMR TASKINEN

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Decreased postprandial high density lipoprotein cholesterol and apolipoproteins A-I and E in normolipidemic smoking men: relations with lipid transfer proteins and LCAT activities.

N MEROA VAN TOLLM SCHEEKT VAN GENTChristine LabeurMaryvonne RosseneuMR TASKINEN

A1 Journal Article in JOURNAL OF LIPID RESEARCH

Displacement of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation of pre-beta(1) migrating particles and decreases LCAT activation.

Christine LabeurG LAMBERTT VAN CAUTERENN DUVERGERB VANLOOJ CHAMBAZJoël VandekerckhoveG CASTROMaryvonne Rosseneu

A1 Journal Article in ATHEROSCLEROSIS

Enhanced efficiency of a targeted fusogenic peptide.

A DECOUTChristine LabeurM GOETHALSR BRASSEURJoël VandekerckhoveMaryvonne Rosseneu

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Kwantitatieve immunologische bepalingen van apolipoproteinen en analyse van de structuur van de apolipoproteinen

Christine LabeurJoë VandekerckhoveMaryvonne Rosseneu

1997

Design of a new class of amphipathic helical peptides for the plasma apolipoproteins that promote cellular cholesterol efflux but do not activate LCAT.

Christine LabeurL LINSBerlinda VanlooJ BAERTR BRASSEURMaryvonne Rosseneu

A1 Journal Article in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Structural and functional properties of the 154-171 wild-type and variant peptides of human lecithin-cholesterol acyltransferase.

Frank PeelmanM GOETHALSB VANLOOChristine LabeurR BRASSEURJoël VandekerckhoveMaryvonne Rosseneu

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

1996

Lipoprotein [a].

A VANDENENDEYY VANDERHOEKJJP KASTELEINML KOSCHINSKYChristine LabeurMaryvonne Rosseneu

A1 Journal Article in ADVANCES IN CLINICAL CHEMISTRY

1995

PHYSIOLOGICAL SIGNIFICANCE OF APOLIPOPROTEIN MUTANTS.

Maryvonne RosseneuChristine Labeur

A1 Journal Article in FASEB JOURNAL

1992

A novel type of acquired form of hypolipoproteinemia

Marc De BuyzereMaryvonne RosseneuJoris DelangheChristine LabeurL NoensJ Baert

A2 Journal Article in CLINICAL CHEMISTRY

Acquired Hypolipoproteinemia.

Marc De BuyzereJoris DelangheChristine LabeurLucien NoensYves BenoitJ BAERTMaryvonne Rosseneu

A1 Journal Article in CLINICAL CHEMISTRY

PLASMA LIPOPROTEIN(A) VALUES AND SEVERITY OF CORONARY-ARTERY DISEASE IN A LARGE POPULATION OF PATIENTS UNDERGOING CORONARY ANGIOGRAPHY.

Christine LabeurDirk De BacquerGui De BackerJ VINCKEL MUYLDERMANSY VANDEKERCKHOVEE VANDERSTICHELEMaryvonne Rosseneu

A1 Journal Article in CLINICAL CHEMISTRY

Plasma lipoprotein(a) values and severity of coronary artery disease in a large population of patients undergoing coronary angiography

Christine LabeurDirk De BacquerGui De BackerJ VINCKEL MUYLDER-MANSY VANDEKERCKHOVE

A2 Journal Article in Clin. Chem., 38, pp. 2261-2266

An unusual case of acquired hypolipaemia and LCAT deficiency. Molecular Biology of Atherosclerosis, P-oceedings of the 57th European Atherosclerosis Society Meeting, Ed. M.J. Halpern, John Libbey & Cie Ltd, Chapter 28, 1992, pp. 137-139.

Marc De BuyzereMaryvonne RosseneuJoris DelangheChristine LabeurL NOENSYves Benoit

An unusual case of acquired hypolipemia and LCAT deficiency. Proc. 57th European Atherosclerosis Society Congress, Lissabon 1991, p. 90.

Marc De BuyzereMaryvonne RosseneuJoris DelangheChristine LabeurL NOENSYves Benoit