Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.

FullPicture: Combining Spectral Flow Cytometry with High-Speed Cell Imaging to enable comprehensive profiling of plant and animal cells and their components in real time.

Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)

Investigating how chronic fibrosis in the liver alters hepatic macrophage responses to systemic infections.

Doctoral project Federico Francesco De Ponti

Investigating the role of Kupffer Cells in Non-alcoholic fatty liver disease

Investigating the role of lipid associated macrophages

Macrophage cell Therapy in Liver Fibrosis

Role of ZEB1 in conventional dendritic cell biology

Understanding Liver Inflammation and cancer in obesity

Doctoral project Bieke Soen

Doctoral project Lasse Vleminckx

Notch-Induced LXRα Expression is Essential for the Maintenance of Kupffer Cell Identity

BOF-ZAP professorship in cellular and molecular immunology

Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)

Investigating the function and development of ‘lipid-associated macrophages’ (LAMs) in liver fibrosis across species.

Investigating the role of Kupffer Cells in driving the progression from NAFLD to Hepatocellular Carcinoma

Investigating the role of ZEB transcription factors in cDC biology

LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapy

Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)

Study of the origins and functions of distinct hepatic macrophage subsets in the pathogenesis of acute liver failure.

Understanding the roles of distinct Kupffer cell activation states in acetaminophen-induced acute liver injury.

Unraveling how ZEB1 expression in conventional type I dendritic cells regulates the presence of other cell types specifically in the spleen and the functional consequences of this regulation.

Unravelling the heterogeneity and functions of hepatic mononuclear phagocytes in Non-Alcoholic Fatty Liver Disease

Development of an AI-driven Spatial Analysis Pipeline (ASAP)

Elucidating the role of liver resident Kupffer cells in the regulation of the immune responses to intestinal antigens

SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomics

The BD FACS Symphony FACS cell sorter: the most advanced multiparameter fluorescence activated cell sorter that allows the identification and purification of rare cells for further functional characterization

Unravelling the cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver disease

BOF-ZAP professorship in cellular and molecular immunology