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Onderzoeker
Bram De Laere
Profiel
Projecten
Publicaties & datasets
Activiteiten
Prijzen & Erkenningen
Octrooien
23
Resultaten
2025
Genomic determinants associated with modes of progression and patterns of failure in metachronous oligometastatic castration-sensitive prostate cancer
Philip Sutera
Yang Song
Amol C. Shetty
Keara English
Kim Van der Eecken
Ozan Cem Guler
Jarey Wang
Yufeng Cao
Soha Bazyar
Sofie Verbeke
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN UROLOGY ONCOLOGY
2025
Prognostic value of the circulating tumor DNA fraction in metastatic castration-resistant prostate cancer : results from the ProBio platform trial
Alessio Crippa
Bram De Laere
Andrea Discacciati
Berit Larsson
Maria Persson
Susanne Johansson
Sanne D'hondt
Marie Hjälm-Eriksson
Linn Pettersson
Gunilla Enblad
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN UROLOGY ONCOLOGY
2025
2024
Androgen deprivation therapy in advanced prostate cancer : insights from a real-world patient survey on health-related quality of life and information and communication sources
Renée Bultijnck
Luc De Laere
Rony De Grande
Thijs Develter
Sophie Vantieghem
Pieter Uvin
Christophe Ghysel
Bram De Laere
[missing] the patient organization Think Blue Vlaanderen vzw
A1
Artikel in een tijdschrift
in
QUALITY OF LIFE RESEARCH
2024
Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer : an outcome-adaptive randomized platform trial
Bram De Laere
Alessio Crippa
Andrea Discacciati
Berit Larsson
Maria Persson
Susanne Johansson
Sanne D'hondt
Rebecka Bergstrom
Venkatesh Chellappa
Markus Mayrhofer
et al.
A1
Artikel in een tijdschrift
in
NATURE MEDICINE
2024
Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer : an outcome-adaptive randomized platform trial (vol 30, pg 3291, 2024)
Bram De Laere
Alessio Crippa
Andrea Discacciati
Berit Larsson
Maria Persson
Susanne Johansson
Sanne D'hondt
Rebecka Bergstrom
Venkatesh Chellappa
Markus Mayrhofer
et al.
Correctie
2024
From mutations to splice variants : identifying liquid biopsy derived biomarkers in metastatic prostate cancer
Jan Vanwelkenhuyzen
Piet Ost
Bram De Laere
Katleen De Preter
Proefschrift
2024
Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping
Evan W. Warner
Kim Van der Eecken
Andrew J. Murtha
Edmond M. Kwan
Cameron Herberts
Joonatan Sipola
Sarah W. S. Ng
Xinyi E. Chen
Nicolette M. Fonseca
Elie Ritch
et al.
A1
Artikel in een tijdschrift
in
NATURE CANCER
2024
2023
AR and PI3K genomic profiling of cell-free DNA can identify poor responders to Lutetium-177-PSMA among patients with metastatic castration-resistant prostate cancer
Jan Vanwelkenhuyzen
Eva Van Bos
Siska Van Bruwaene
Karl Lesage
Alex Maes
Sezgin Üstmert
Filip Lavent
Laurence Beels
Henrik Grönberg
Piet Ost
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN UROLOGY OPEN SCIENCE
2023
Genomic determinants of patterns of failure in metachronous oligometastatic castration-sensitive prostate cancer
Philip Sutera
Kim Van der Eecken
Amol Shetty
Yang Song
Theresa Hodges
Sofie Verbeke
Jo Van Dorpe
Valerie Fonteyne
Bram De Laere
Mark V. Mishra
et al.
C3
Conferentie
2023
Overcoming complex polyclonality for accurate clinical genotyping in metastatic prostate cancer
Alexander W. Wyatt
Andrew J. Murtha
Evan Warner
Kim Van der Eecken
Edmond M. Kwan
Cameron Herberts
Joonatan Sipola
Sarah W. S. Ng
Xinyi E. Chen
Nicolette M. Fonseca
et al.
C3
Conferentie
2023
WNT pathway mutations in metachronous oligometastatic castration-sensitive prostate cancer
Philip Sutera
Matthew P. Deek
Kim Van der Eecken
Amol C. Shetty
Jin Hee Chang
Theresa Hodges
Yang Song
Sofie Verbeke
Jo Van Dorpe
Valerie Fonteyne
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
2023
2022
Clinical trial protocol for ProBio : an outcome-adaptive and randomised multiarm biomarker-driven study in patients with metastatic prostate cancer
Bram De Laere
Alessio Crippa
Andrea Discacciati
Berit Larsson
Jan Oldenburg
Ashkan Mortezavi
Piet Ost
Martin Eklund
Johan Lindberg
Henrik Gronberg
et al.
Redactioneel materiaal
2022
Multi-focal genomic dissection of synchronous primary and metastatic tissue from de novo metastatic prostate cancer
A. J. Murtha
E. Warner
Kim Van der Eecken
E. Kwan
C. Herberts
J. Sipola
S. Ng
E. Chen
N. Fonseca
E. Schonlau
et al.
C3
Conferentie
2022
Toward methodology for comprehensive androgen receptor splice variant profiling in cell-free RNA from patients with metastatic prostate cancer
Jan Vanwelkenhuyzen
Pieter-Jan van Dam
Katleen De Preter
Johan Lindberg
Piet Ost
Bram De Laere
C3
Conferentie
2022
Towards the discovery of prognostic and predictive biomarkers in CHEERS, a radioimmunotherapy phase II trial
Jan Vanwelkenhuyzen
Mathieu Spaas
Kim Van der Eecken
Vibeke Kruse
Sylvie Rottey
Lieve Brochez
Johan Lindberg
Katleen De Preter
Bram De Laere
Piet Ost
C3
Conferentie
2022
2021
Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer
S Oeyen
V Liégeois
Bram De Laere
A Buys
M Strijbos
P Dirix
P Meijnders
P Vermeulen
S Van Laere
L Dirix
A1
Artikel in een tijdschrift
in
PROSTATE CANCER AND PROSTATIC DISEASES
2021
Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization
Gabriel Renaud
Maibritt Nørgaard
Johan Lindberg
Henrik Grönberg
Bram De Laere
Jørgen Bjerggaard Jensen
Michael Borre
Claus Lindbjerg Andersen
Karina Dalsgaard Sørensen
Lasse Maretty
et al.
Preprint
2021
Evaluation of a marker independent isolation method for circulating tumor cells in esophageal adenocarcinoma
Annouck Philippron
Lieven Depypere
Steffi Oeyen
Bram De Laere
Charlotte Vandeputte
Philippe Nafteux
Katleen De Preter
Piet Pattyn
A1
Artikel in een tijdschrift
in
PLOS ONE
2021
Increased pathway complexity is a prognostic biomarker in metastatic castration-resistant prostate cancer
Bram De Laere
A Crippa
A Mortezavi
C Ghysel
P Rajan
M Eklund
A Wyatt
L Dirix
Piet Ost
H Grönberg
et al.
A1
Artikel in een tijdschrift
in
CANCERS
2021
Multifocality in prostate cancer : implications for PAM50 subtyping using an index lesion-only approach
Kim Van der Eecken
Maarten Larmuseau
Jan Vanwelkenhuyzen
Nicolaas Lumen
Kathleen Marchal
Jo Van Dorpe
Piet Ost
Bram De Laere
Sofie Verbeke
C3
Conferentie
2021
Tissue- and blood-derived genomic biomarkers for metastatic hormone-sensitive prostate cancer : a systematic review
Kim Van der Eecken
Jan Vanwelkenhuyzen
Matthew P. Deek
Phuoc T. Tran
Evan Warner
Alexander W. Wyatt
Edmond M. Kwan
Sofie Verbeke
Jo Van Dorpe
Valerie Fonteyne
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN UROLOGY ONCOLOGY
2021
2020
Inferring the genomic landscape of lymph-node positive high-risk prostate cancer
Jan Vanwelkenhuyzen
Kim Van der Eecken
Bram De Laere
Simon Sundling
Rebecka Bergström
Johan Lindberg
Katleen De Preter
Henrik Grönberg
Piet Ost
C3
Conferentie
2020
The ProBio trial : molecular biomarkers for advancing personalized treatment decision in patients with metastatic castration-resistant prostate cancer
Alessio Crippa
Bram De Laere
Andrea Discacciati
Berit Larsson
Jason T. Connor
Erin E. Gabriel
Camilla Thellenberg
Elin Janes
Gunilla Enblad
Anders Ullen
et al.
A1
Artikel in een tijdschrift
in
TRIALS
2020