Research Explorer

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Researcher

Bram De Laere

Publications & Research Data

Awards & Distinctions

23 Results

2025

Genomic determinants associated with modes of progression and patterns of failure in metachronous oligometastatic castration-sensitive prostate cancer

Philip SuteraYang SongAmol C. ShettyKeara EnglishKim Van der EeckenOzan Cem GulerJarey WangYufeng CaoSoha BazyarSofie Verbeke et al.

A1 Journal Article in EUROPEAN UROLOGY ONCOLOGY

Prognostic value of the circulating tumor DNA fraction in metastatic castration-resistant prostate cancer : results from the ProBio platform trial

Alessio CrippaBram De LaereAndrea DiscacciatiBerit LarssonMaria PerssonSusanne JohanssonSanne D'hondtMarie Hjälm-ErikssonLinn PetterssonGunilla Enblad et al.

A1 Journal Article in EUROPEAN UROLOGY ONCOLOGY

2024

Androgen deprivation therapy in advanced prostate cancer : insights from a real-world patient survey on health-related quality of life and information and communication sources

Renée BultijnckLuc De LaereRony De GrandeThijs DevelterSophie VantieghemPieter UvinChristophe GhyselBram De Laere[missing] the patient organization Think Blue Vlaanderen vzw

A1 Journal Article in QUALITY OF LIFE RESEARCH

Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer : an outcome-adaptive randomized platform trial

Bram De LaereAlessio CrippaAndrea DiscacciatiBerit LarssonMaria PerssonSusanne JohanssonSanne D'hondtRebecka BergstromVenkatesh ChellappaMarkus Mayrhofer et al.

A1 Journal Article in NATURE MEDICINE

Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer : an outcome-adaptive randomized platform trial (vol 30, pg 3291, 2024)

Bram De LaereAlessio CrippaAndrea DiscacciatiBerit LarssonMaria PerssonSusanne JohanssonSanne D'hondtRebecka BergstromVenkatesh ChellappaMarkus Mayrhofer et al.

From mutations to splice variants : identifying liquid biopsy derived biomarkers in metastatic prostate cancer

Jan VanwelkenhuyzenPiet OstBram De LaereKatleen De Preter

Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping

Evan W. WarnerKim Van der EeckenAndrew J. MurthaEdmond M. KwanCameron HerbertsJoonatan SipolaSarah W. S. NgXinyi E. ChenNicolette M. FonsecaElie Ritch et al.

A1 Journal Article in NATURE CANCER

2023

AR and PI3K genomic profiling of cell-free DNA can identify poor responders to Lutetium-177-PSMA among patients with metastatic castration-resistant prostate cancer

Jan VanwelkenhuyzenEva Van BosSiska Van BruwaeneKarl LesageAlex MaesSezgin ÜstmertFilip LaventLaurence BeelsHenrik GrönbergPiet Ost et al.

A1 Journal Article in EUROPEAN UROLOGY OPEN SCIENCE

Genomic determinants of patterns of failure in metachronous oligometastatic castration-sensitive prostate cancer

Philip SuteraKim Van der EeckenAmol ShettyYang SongTheresa HodgesSofie VerbekeJo Van DorpeValerie FonteyneBram De LaereMark V. Mishra et al.

Overcoming complex polyclonality for accurate clinical genotyping in metastatic prostate cancer

Alexander W. WyattAndrew J. MurthaEvan WarnerKim Van der EeckenEdmond M. KwanCameron HerbertsJoonatan SipolaSarah W. S. NgXinyi E. ChenNicolette M. Fonseca et al.

WNT pathway mutations in metachronous oligometastatic castration-sensitive prostate cancer

Philip SuteraMatthew P. DeekKim Van der EeckenAmol C. ShettyJin Hee ChangTheresa HodgesYang SongSofie VerbekeJo Van DorpeValerie Fonteyne et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

2022

Clinical trial protocol for ProBio : an outcome-adaptive and randomised multiarm biomarker-driven study in patients with metastatic prostate cancer

Bram De LaereAlessio CrippaAndrea DiscacciatiBerit LarssonJan OldenburgAshkan MortezaviPiet OstMartin EklundJohan LindbergHenrik Gronberg et al.

Editorial material

Multi-focal genomic dissection of synchronous primary and metastatic tissue from de novo metastatic prostate cancer

A. J. MurthaE. WarnerKim Van der EeckenE. KwanC. HerbertsJ. SipolaS. NgE. ChenN. FonsecaE. Schonlau et al.

Toward methodology for comprehensive androgen receptor splice variant profiling in cell-free RNA from patients with metastatic prostate cancer

Jan VanwelkenhuyzenPieter-Jan van DamKatleen De PreterJohan LindbergPiet OstBram De Laere

Towards the discovery of prognostic and predictive biomarkers in CHEERS, a radioimmunotherapy phase II trial

Jan VanwelkenhuyzenMathieu SpaasKim Van der EeckenVibeke KruseSylvie RotteyLieve BrochezJohan LindbergKatleen De PreterBram De LaerePiet Ost

2021

Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer

S OeyenV LiégeoisBram De LaereA BuysM StrijbosP DirixP MeijndersP VermeulenS Van LaereL Dirix

A1 Journal Article in PROSTATE CANCER AND PROSTATIC DISEASES

Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization

Gabriel RenaudMaibritt NørgaardJohan LindbergHenrik GrönbergBram De LaereJørgen Bjerggaard JensenMichael BorreClaus Lindbjerg AndersenKarina Dalsgaard SørensenLasse Maretty et al.

Evaluation of a marker independent isolation method for circulating tumor cells in esophageal adenocarcinoma

Annouck PhilippronLieven DepypereSteffi OeyenBram De LaereCharlotte VandeputtePhilippe NafteuxKatleen De PreterPiet Pattyn

A1 Journal Article in PLOS ONE

Increased pathway complexity is a prognostic biomarker in metastatic castration-resistant prostate cancer

Bram De LaereA CrippaA MortezaviC GhyselP RajanM EklundA WyattL DirixPiet OstH Grönberg et al.

A1 Journal Article in CANCERS

Multifocality in prostate cancer : implications for PAM50 subtyping using an index lesion-only approach

Kim Van der EeckenMaarten LarmuseauJan VanwelkenhuyzenNicolaas LumenKathleen MarchalJo Van DorpePiet OstBram De LaereSofie Verbeke

Tissue- and blood-derived genomic biomarkers for metastatic hormone-sensitive prostate cancer : a systematic review

Kim Van der EeckenJan VanwelkenhuyzenMatthew P. DeekPhuoc T. TranEvan WarnerAlexander W. WyattEdmond M. KwanSofie VerbekeJo Van DorpeValerie Fonteyne et al.

A1 Journal Article in EUROPEAN UROLOGY ONCOLOGY

2020

Inferring the genomic landscape of lymph-node positive high-risk prostate cancer

Jan VanwelkenhuyzenKim Van der EeckenBram De LaereSimon SundlingRebecka BergströmJohan LindbergKatleen De PreterHenrik GrönbergPiet Ost

The ProBio trial : molecular biomarkers for advancing personalized treatment decision in patients with metastatic castration-resistant prostate cancer

Alessio CrippaBram De LaereAndrea DiscacciatiBerit LarssonJason T. ConnorErin E. GabrielCamilla ThellenbergElin JanesGunilla EnbladAnders Ullen et al.

A1 Journal Article in TRIALS