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Onderzoeker
Björn Menten
Profiel
Projecten
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Activiteiten
Prijzen & Erkenningen
347
Resultaten
2024
198 Assessment of biphasic CAPA-IVM for improving equine oocyte quality and developmental potential
Muhammad Fakhar-I-Adil
Daniel Angel Velez
Qurratul Ain Amin
Mohamed Hedia
Björn Menten
Ann Van Soom
Katrien Smits
Björn Heindryckx
U
Artikel in een tijdschrift
in
Reproduction, Fertility and Development
2024
Advancing diagnosis and early risk assessment of preeclampsia through noninvasive cell-free DNA methylation profiling
Machteld Baetens
Bram Van Gaever
Stephanie Deblaere
Andries De Koker
Leander Meuris
Nico Callewaert
Sandra Janssens
Kristien Roelens
Ellen Roets
Jo Van Dorpe
et al.
U
Artikel in een tijdschrift
in
Clinical Epigenetics
2024
Aligning genotyping and copy number data in single trophectoderm biopsies for aneuploidy prediction : uncovering incomplete concordance
Lisa De Witte
Machteld Baetens
Kelly Tilleman
Frauke Vanden Meerschaut
Sandra Janssens
Ariane Van Tongerloo
Virginie Szymczak
Dominic Stoop
Annelies Dheedene
Sofie Symoens
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION OPEN
2024
Clinical impact of RNA-sequencing in diagnostics
Laurenz De Cock
Erika D'haenens
Sarah Vergult
Lies Vantomme
Annelies Dheedene
Robin de Putter
Tim Van Damme
Jo Sourbron
Bert Callewaert
Olivier Vanakker
et al.
U
Conferentie
2024
Effect of biphasic CAPA-IVM on ovarian tissue oocytes of transgender men
Muhammad Fakhar-I-Adil
Antonia Christodoulaki
Susana Marina Chuva de Sousa Lopes
Steven Weyers
Björn Menten
Ann Van Soom
Dominic Stoop
Chloë De Roo
Björn Heindryckx
C3
Conferentie
2024
Feasibility of haploidization to reconstruct de novo oocytes
Winter Vandenberghe
Andrei Rybouchkin
Dominic Stoop
Björn Menten
Björn Heindryckx
U
Conferentie
2024
Generation of a human induced pluripotent stem cell line UGENTi002-A from an arrhythmogenic cardiomyopathy patient carrying the c.817C>T DSP heterozygous variant and isogenic control using CRISPR/Cas9 editing
Laurens Léger
Jeffrey Aalders
Nina Heymans
Kiara Van Acker-Verberckt
Léa De Bleeckere
Paul Coucke
Björn Menten
Barbara Bauce
Libero Vitiello
Alessandra Rampazzo
et al.
A1
Artikel in een tijdschrift
in
STEM CELL RESEARCH
2024
Haploinsufficiency of ZFHX3, encoding a key player in neuronal development, causes syndromic intellectual disability
Maria del Rocio Pérez Baca
Eva Jacobs
Lies Vantomme
Pontus LeBlanc
Elke Bogaert
Annelies Dheedene
Laurenz De Cock
Sadegheh Haghshenas
Aidin Foroutan
Michael A Levy
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF HUMAN GENETICS
2024
Implicit bias in diagnosing mosaicism amongst preimplantation genetic testing providers : results from a multicenter study of 36 395 blastocysts
Mina Popovic
Lorena Borot
Aline R. Lorenzon
Ana Luiza Rossi de Castro Lopes
Denny Sakkas
Belen Lledo
Ruth Morales
Jose Antonio Ortiz
Nikolaos Polyzos
Monica Parriego
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder
Maria del Rocio Pérez Baca
Maria Palomares
Michiel Vanhooydonck
Eva D'haene
Eva Z. Jacobs
Lies Vantomme
Fernando Santos-Simarro
Roser Lleuger-Pujol
Sixto García-Miñaúr
Itsaso Losantos-García
et al.
C3
Conferentie
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder
Maria del Rocio Pérez Baca
Maria Palomares
Michiel Vanhooydonck
Eva D'haene
Eva Jacobs
Lies Vantomme
Fernando Santos-Simarro
Roser Lleuger-Pujol
Sixto García-Miñáur
Itsaso Losantos-García
et al.
C3
Conferentie
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder
Maria del Rocio Pérez Baca
María Palomares Bralo
Michiel Vanhooydonck
Lisa Hamerlinck
Eva D'haene
Sebastian Leimbacher
Eva Jacobs
Laurenz De Cock
Erika D'haenens
Annelies Dheedene
et al.
Preprint
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder
Maria del Rocio Pérez Baca
Maria Palomares Bralo
Michiel Vanhooydonck
Lisa Hamerlinck
Eva D'haene
Sebastian Leimbacher
Eva Jacobs
Laurenz De Cock
Erika D'haenens
Zoë Malfait
et al.
C3
Conferentie
2024
Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum
Joline Ingels
Laurenz De Cock
Dieter Stevens
Rupert Mayer
Fabien Henri Thery
Guillem Sanchez Sanchez
David Vermijlen
Karin Weening
Saskia De Smet
Nele Lootens
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS MEDICINE
2024
Pronuclear transfer rescues poor embryo development of in vitro-grown secondary mouse follicles
Antonia Christodoulaki
Haitang He
Min Zhou
Chloë De Roo
Machteld Baetens
Tine De Pretre
Muhammad Fakhar-I-Adil
Björn Menten
Ann Van Soom
Dominic Stoop
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION OPEN
2024
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Maria del Rocio Pérez Baca
Sarah Vergult
Bert Callewaert
Elfride De Baere
Björn Menten
Lies Vantomme
Michael B Vaughan
C3
Conferentie
2024
2023
BeSolveRD : the Belgian genome resource to resolve rare diseases
Mathilde Geysens
Wouter Bossuyt
Elfride De Baere
Kim De Leeneer
Koenraad Devriendt
Annelies Dheedene
Aime Lumaka
Jeroen Luyten
Gert Matthijs
Björn Menten
et al.
C3
Conferentie
2023
CRISPR/Cas9-based correction of infertility-related mutations in the germline : ready or not?
Bieke Bekaert
Björn Heindryckx
Annekatrien Boel
Björn Menten
Proefschrift
2023
Characterization of ovarian tissue oocytes from transgender men reveals poor calcium release and embryo development, which might be overcome by spindle transfer
Antonia Christodoulaki
Haitang He
Min Zhou
Arantxa Cardona Barberán
Chloë De Roo
Susana Marina Chuva de Sousa Lopes
Machteld Baetens
Björn Menten
Ann Van Soom
Petra De Sutter
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2023
Effect of biphasic CAPA-IVM on ovarian tissue oocytes of transgender men
Muhammad Fakhar-I-Adil
Antonia Christodoulaki
Annekatrien Boel
Susana Marina Chuva de Sousa Lopes
Björn Menten
Ann Van Soom
Dominic Stoop
Chloë De Roo
Björn Heindryckx
C3
Conferentie
2023
Generation of human induced pluripotent stem cell line UGENTi001-A from a patient with Marfan syndrome carrying a heterozygous c.7754 T > C variant in FBN1 and the isogenic control UGENT001-A-1 using CRISPR/Cas9 editing
Jeffrey Aalders
Laurens Léger
Anthony Demolder
Laura Muiño Mosquera
Paul Coucke
Björn Menten
Julie De Backer
Jolanda van Hengel
A1
Artikel in een tijdschrift
in
STEM CELL RESEARCH
2023
Inherited pathogenic variants in neurodevelopmental disorders : a potential pitfall in triobased analysis of clinical exomes
Annelies Dheedene
Erika D'haenens
Evelien Pouillie
Sarah Delbaere
Olivier Vanakker
Bert Callewaert
Björn Menten
C3
Conferentie
2023
Long-read sequencing and optical genome mapping enable full characterization of previously unresolved structural variation
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Wouter De Coster
Mojca Strazisar
Tim De Pooter
Barbara Dewaele
Joris Vermeesch
Annelies Dheedene
et al.
C3
Conferentie
2023
Long-read sequencing and optical genome mapping enable full characterization of previously unresolved structural variation
Griet De Clercq
Lies Vantomme
Bert Callewaert
Barbara Dewaele
Joris Vermeesch
Annelies Dheedene
Björn Menten
C3
Conferentie
2023
Long-read sequencing enables full characterization of previously unresolved structural variation
Griet De Clercq
Lies Vantomme
Bert Callewaert
Annelies Dheedene
Björn Menten
C3
Conferentie
2023
Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conferentie
2023
Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conferentie
2023
Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conferentie
2023
MIDRIXNEO-LUNG : safety and immunogenicity of a neoantigen-presenting autologous dendritic cell therapy in resected NSCLC patients
Joline Ingels
Laurenz De Cock
Dieter Stevens
Karin Weening
Veerle Surmont
Jo Van Dorpe
Francis Impens
Björn Menten
Karim Vermaelen
Bart Vandekerckhove
C3
Conferentie
2023
Nuclear transfer overcomes poor embryo development of in vitro grown mouse oocytes
Antonia Christodoulaki
H. He
M. Zhou
C. De Roo
M. Baetens
Björn Menten
Ann Van Soom
Dominic Stoop
A. Boel
Björn Heindryckx
C3
Conferentie
2023
Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Winter Vandenberghe
Mina Popovic
Panagiotis Stamatiadis
Gwenny Cosemans
Lise Tordeurs
Athina-Maria De Loore
Susana Marina Chuva de Sousa Lopes
et al.
A1
Artikel in een tijdschrift
in
MOLECULAR THERAPY
2023
Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage
Lore Billiet
Laurenz De Cock
Guillem Sanchez Sanchez
Rupert Mayer
Glenn Goetgeluk
Stijn De Munter
Melissa Pille
Joline Ingels
Hanne Jansen
Karin Weening
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Michael B Vaughan
Maria del Rocio Pérez Baca
Nore Van Loon
Lies Vantomme
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conferentie
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Sarah Vergult
Nore Van Loon
Maria del Rocio Pérez Baca
Lies Vantomme
Michael B Vaughan
Elfride De Baere
Bert Callewaert
Björn Menten
C3
Conferentie
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Eva D'haene
Lies Vantomme
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conferentie
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Maria del Rocio Pérez Baca
Lies Vantomme
Nore Van Loon
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conferentie
2023
Valuable insights after one year whole exome sequencing in a fetal/prenatal setting
Sarah Delbaere
Machteld Baetens
Candy Kumps
Ellen Roets
Noortje Van Oostrum
Bert Callewaert
Sandra Janssens
Olivier Vanakker
Björn Menten
C3
Conferentie
2023
2022
A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 (ZFHX3) gene
Maria del Rocio Pérez Baca
Eva Jacobs
Lies Vantomme
Pontus LeBlanc
Elke Bogaert
Annelies Dheedene
Laurenz De Cock
Bart Dermaut
Aidin Foroutan
Jennifer Kerkhof
et al.
C3
Conferentie
2022
Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome
Malaïka Van der Linden
Bram Van Gaever
Lennart Raman
Karim Vermaelen
Ingel Demedts
Veerle Surmont
Ulrike Himpe
Yolande Lievens
Liesbeth Ferdinande
Franceska Dedeurwaerdere
et al.
A1
Artikel in een tijdschrift
in
CANCERS
2022
Benchmarking of long read structural variant callers using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conferentie
2022
Benchmarking of long-read structural variant callers using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conferentie
2022
Benchmarking of long-read structural variant callers using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conferentie
2022
Benchmarking of long-read structural variant callers using in-house generated Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conferentie
2022
CRISPR/Cas gene editing in the human germline
Bieke Bekaert
Annekatrien Boel
Gwenny Cosemans
Lisa De Witte
Björn Menten
Björn Heindryckx
A1
Artikel in een tijdschrift
in
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
2022
Comparison of the positivity rate of anti-spike and anti-nucleocapsid SARS-CoV-2 IgG in asymptomatic pregnant women
Laura Heireman
Machteld Baetens
Björn Menten
Isabelle Dehaene
Elizaveta Padalko
A1
Artikel in een tijdschrift
in
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
2022
Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Gwenny Cosemans
Lise Tordeurs
Athina-Maria De Loore
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
Dominic Stoop
Paul Coucke
et al.
C3
Conferentie
2022
Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Gwenny Cosemans
Susana Marina Chuva de Sousa Lopes
Björn Menten
Björn Heindryckx
C3
Conferentie
2022
Expanding the phenotype of B3GALNT2-related disorders
Erika D'haenens
Sarah Vergult
Björn Menten
Annelies Dheedene
R. Frank Kooy
Bert Callewaert
A1
Artikel in een tijdschrift
in
GENES
2022
GENType : all-in-one preimplantation genetic testing by pedigree haplotyping and copy number profiling suitable for third-party reproduction
Lisa De Witte
Lennart Raman
Machteld Baetens
Andries De Koker
Nico Callewaert
Sofie Symoens
Kelly Tilleman
Frauke Vanden Meerschaut
Annelies Dheedene
Björn Menten
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2022
Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI
Maoxing Tang
Annekatrien Boel
Noemi Castelluccio
Arantxa Cardona Barberán
Antonia Christodoulaki
Bieke Bekaert
Mina Popovic
Frauke Vanden Meerschaut
Petra De Sutter
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
2022
Liquid biopsies for integrated cancer (differential) diagnosis : from whole-genome to targeted and from genomics to epigenomics
Malaïka Van der Linden
Jo Van Dorpe
Björn Menten
Kathleen Claes
Proefschrift
2022
Long-read sequencing resolves cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conferentie
2022
Long-read sequencing to unravel complex structural variants of CEP78 leading to cone-rod dystrophyand hearing loss
Giulia Ascari
Nanna D. Rendtorff
Marieke De Bruyne
Julie De Zaeytijd
Michel Van Lint
Mattias Van Heetvelde
Gavin Arno
Julie Jacob
David Creytens
Jo Van Dorpe
et al.
C3
Conferentie
2022
Luminescent human iPSC-derived neurospheroids enable modeling of neurotoxicity after oxygen-glucose deprivation
Elise Van Breedam
Aleksandra Nijak
Tamariche Buyle-Huybrecht
Julia Di Stefano
Marlies Boeren
Jonas Govaerts
Alessandra Quarta
Tine Swartenbroekx
Eva Jacobs
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
NEUROTHERAPEUTICS
2022
MYT1L-associated neurodevelopmental disorder : description of 40 new cases and literature review of clinical and molecular aspects
Juliette Coursimault
Anne-Marie Guerrot
Michelle M. Morrow
Catherine Schramm
Francisca Millan Zamora
Anita Shanmugham
Shuxi Liu
Fanggeng Zou
Frederic Bilan
Gwenael Le Guyader
et al.
A1
Artikel in een tijdschrift
in
HUMAN GENETICS
2022
Phenotypic and molecular heterogeneity in mandibulofacial dysostoses : a case series from India
Rathika D. Shenoy
Vikram Shetty
Annelies Dheedene
Björn Menten
Dechamma Pandyanda Nanjappa
Gunimala Chakraborty
Patrick Sips
Anne De Paepe
Bert Callewaert
Anirban Chakraborty
A1
Artikel in een tijdschrift
in
CLEFT PALATE-CRANIOFACIAL JOURNAL
2022
Pushing the boundaries : concurrent Hodgkin lymphoma and breast cancer treatment with preservation of pregnancy : a case report
Charlotte Lejeune
Daan Dierickx
Hans Wildiers
Lore Lannoo
Kristel Van Calsteren
Vincent Vandecaveye
Björn Menten
Joris Vermeesch
Frédéric Amant
A2
Artikel in een tijdschrift
in
GYNECOLOGIC ONCOLOGY REPORTS
2022
Shallow whole-genome sequencing : a useful, easy to apply molecular technique for CNA detection on FFPE tumor tissue : a glioma-driven study
Kim Van der Eecken
Malaïka Van der Linden
Lennart Raman
David Creytens
Franceska Dedeurwaerdere
Koen De Winne
Liesbeth Ferdinande
Martin Lammens
Björn Menten
Isabelle Rottiers
et al.
A1
Artikel in een tijdschrift
in
VIRCHOWS ARCHIV
2022
Shallow-depth sequencing of cell-free DNA for Hodgkin and diffuse large B-cell lymphoma (differential) diagnosis : a standardized approach with underappreciated potential
Lennart Raman
Malaïka Van der Linden
Ciel De Vriendt
Bliede Van den Broeck
Kristoff Muylle
Dries Deeren
Franceska Dedeurwaerdere
Sofie Verbeke
Amélie Dendooven
Katrien De Grove
et al.
A1
Artikel in een tijdschrift
in
HAEMATOLOGICA
2022
Shallow-depth sequencing of cell-free DNA for Hodgkin and diffuse large B-cell lymphoma (differential) diagnosis: a standardized approach with underappreciated potential
Lennart Raman
Malaïka Van Der Linden
Ciel De Vriendt
Bliede Van den Broeck
Kristoff Muylle
Dries Deeren
Franceska Dedeurwaerdere
Sofie Verbeke
Amélie Dendooven
Katrien De Grove
et al.
U
Artikel in een tijdschrift
in
Haematologica
2022
Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials
Joline Ingels
Laurenz De Cock
Rupert Mayer
Pam Devreker
Karin Weening
Kelly Heyns
Nele Lootens
Saskia De Smet
Marieke Brusseel
Stijn De Munter
et al.
A1
Artikel in een tijdschrift
in
CYTOTHERAPY
2022
Spindle transfer rescues poor embryo development of in vitro matured ovarian tissue oocytes from transgender men
Antonia Christodoulaki
H. He
M. Zhou
Arantxa Cardona Barberán
Chloë De Roo
S. M. Chuva De Sousa Lopes
Björn Menten
Ann Van Soom
Petra De Sutter
Annekatrien Boel
et al.
C3
Conferentie
2022
TEAD4 regulates trophectoderm differentiation upstream of CDX2 in a GATA3-independent manner in the human preimplantation embryo
Panagiotis Stamatiadis
Gwenny Cosemans
Annekatrien Boel
Björn Menten
Petra De Sutter
Dominic Stoop
Susana Marina Chuva de Sousa Lopes
Frederic Lluis
Paul Coucke
Björn Heindryckx
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2022
The adrenergic-specific long non-coding RNA NESPR controls survival of neuroblastoma cells
Louis Delhaye
Eric de Bony de Lavergne
Dries Rombaut
Lim Fang Qi
Bieke Decaesteker
Lisa Depestel
Amber Louwagie
Eva D'haene
Pieter-Jan Volders
Nurten Yigit
et al.
C3
Conferentie
2022
The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples
Ruben Van Paemel
Charlotte Vandeputte
Lennart Raman
Jolien Van Thorre
Leen Willems
Jo Van Dorpe
Malaïka Van der Linden
Jilke De Wilde
Andries De Koker
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF CANCER
2022
Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models
Kiana Mohajeri
Rachita Yadav
Eva D'haene
Philip M. Boone
Serkan Erdin
Dadi Gao
Mariana Moyses-Oliveira
Riya Bhavsar
Benjamin Currall
Kathryn O’Keefe
et al.
Preprint
2022
Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models
Kiana Mohajeri
Rachita Yadav
Eva D'haene
Philip M. Boone
Serkan Erdin
Dadi Gao
Mariana Moyses-Oliveira
Riya Bhavsar
Benjamin B. Currall
Kathryn O'Keefe
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF HUMAN GENETICS
2022
2021
A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 gene (ZFHX3)
Maria del Rocio Pérez Baca
Eva Jacobs
Lies Vantomme
Mareike Bauer
Melissa Bellini
Claire Beneteau
Natasha Brown
David Coman
Laurenz De Cock
Annelies Dheedene
et al.
C3
Conferentie
2021
A reassessment of copy number variations in congenital heart defects : picturing the whole genome
Ilse Meerschaut
Sarah Vergult
Annelies Dheedene
Björn Menten
Katya De Groote
Hans De Wilde
Laura Muiño Mosquera
Joseph Panzer
Kristof Vandekerckhove
Paul Coucke
et al.
A1
Artikel in een tijdschrift
in
GENES
2021
Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells
Swati Mishra
Jasin Taelman
Mina Popovic
Laurentijn Tilleman
Evi Duthoo
Margot Van der Jeught
Dieter Deforce
Filip Van Nieuwerburgh
Björn Menten
Petra De Sutter
et al.
A1
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in
STEM CELLS
2021
Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conferentie
2021
Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conferentie
2021
CRISPR-ing the gap between discovery and validation of candidate genes for neurodevelopmental disorders
Eva Jacobs
Sarah Vergult
Bert Callewaert
Björn Menten
Proefschrift
2021
Calcium analysis and embryonic development of in vitro matured oocytes from transgender men
Antonia Christodoulaki
Haitang He
Arantxa Cardona Barberán
Chloë De Roo
Susana Marina Chuva de Sousa Lopes
Björn Menten
Ann Van Soom
Petra De Sutter
Dominic Stoop
Annekatrien Boel
et al.
C3
Conferentie
2021
Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences
Panagiotis Stamatiadis
Annekatrien Boel
Gwenny Cosemans
Mina Popovic
Bieke Bekaert
Ramesh Reddy Guggilla
Maoxing Tang
Petra De Sutter
Filip Van Nieuwerburgh
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2021
Copy number and methylation profiling of cell-free DNA for tumor and prenatal diagnostics : a multi-cohort research effort
Lennart Raman
Jo Van Dorpe
Björn Menten
Proefschrift
2021
Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility
Bieke Bekaert
Annekatrien Boel
Mina Popovic
Panagiotis Stamatiadis
S M Chuva de Sousa Lopes
Petra De Sutter
Björn Menten
Dominic Stoop
Paul Coucke
Björn Heindryckx
C3
Conferentie
2021
Long-read sequencing to unravel complex structural variants of CEP78 leading to cone-rod dystrophy and hearing loss
Giulia Ascari
Nanna Rendtorff
Marieke De Bruyne
Julie De Zaeytijd
Michel Van Lint
Mattias Van Heetvelde
Alfredo Dueñas Rey
Gavin Arno
Julie Jacob
David Creytens
et al.
C3
Conferentie
2021
Long-read sequencing to unravel complex structural variants of CEP78 leading to cone-rod dystrophy and hearing loss
Giulia Ascari
Nanna D. Rendtorff
Marieke De Bruyne
Julie De Zaeytijd
Michel Van Lint
Miriam Bauwens
Mattias Van Heetvelde
Gavin Arno
Julie Jacob
David Creytens
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021
Long-read sequencing to unravel complex structural variants of CEP78 leading to cone‐rod dystrophy and hearing loss
Giulia Ascari
Nanna D Rendtorff
Marieke De Bruyne
Julie De Zaeytijd
Michel Van Lint
Mattias Van Heetvelde
Alfredo Dueñas Rey
Gavin Arno
Julie Jacob
David Creytens
et al.
C3
Conferentie
2021
Low feasibility of in vitro matured oocytes originating from cumulus complexes found during ovarian tissue preparation at the moment of gender confirmation surgery and during testosterone treatment for fertility preservation in transgender men
Sylvie Lierman
Annelies Tolpe
Ilse De Croo
Stefanie De Gheselle
Justine Defreyne
Machteld Baetens
Annelies Dheedene
Roos Colman
Björn Menten
Guy T'Sjoen
et al.
A1
Artikel in een tijdschrift
in
FERTILITY AND STERILITY
2021
Myxoid pleomorphic liposarcoma : a clinicopathologic, immunohistochemical, molecular genetic and epigenetic study of 12 cases, suggesting a possible relationship with conventional pleomorphic liposarcoma
David Creytens
Andrew L. Folpe
Christian Koelsche
Thomas Mentzel
Liesbeth Ferdinande
Joost M. van Gorp
Malaïka Van der Linden
Lennart Raman
Björn Menten
Karen Fritchie
et al.
A1
Artikel in een tijdschrift
in
MODERN PATHOLOGY
2021
Neurodevelopmental disorders in 3D : interpreting the impact of non-coding structural variation on gene regulation and 3D chromatin structure
Eva D'haene
Sarah Vergult
Björn Menten
Proefschrift
2021
Outcome of publicly funded nationwide first-tier noninvasive prenatal screening
Kris Van den Bogaert
Lore Lannoo
Nathalie Brison
Vincent Gatinois
Machteld Baetens
Bettina Blaumeiser
Francois Boemer
Laura Bourlard
Vincent Bours
Anne De Leener
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2021
Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
Liselot Mus
Stéphane Van Haver
Mina Popovic
Wim Trypsteen
Steve Lefever
Nadja Zeltner
Yudelca Ogando
Eva Jacobs
Geertrui Denecker
Ellen Sanders
et al.
A1
Artikel in een tijdschrift
in
GENES CHROMOSOMES & CANCER
2021
SOX11 as guardian of epigenetic plasticity in neuroblastoma
Bieke Decaesteker
Amber Louwagie
Siebe Loontiens
Sara De Brouwer
Carolina de Carvalho Nunes
Geertrui Denecker
Fanny De Vloed
Lisa Depestel
Juliette Roels
Karen Verboom
et al.
C3
Conferentie
2021
Structural variants disrupt a critical regulatory region downstream of FOXG1
Eva D'haene
Lies Vantomme
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conferentie
2021
TEAD4 regulates trophectoderm differentiation upstream of CDX2 in human preimplantation embryos
Panagiotis Stamatiadis
Annekatrien Boel
Gwenny Cosemans
Filip Van Nieuwerburgh
Björn Menten
Petra De Sutter
Dominic Stoop
S. M. Chuva de Sousa Lopes
F. Lluis
C3
Conferentie
2021
2020
A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line
Bieke Bekaert
Annekatrien Boel
Lisa De Witte
Mina Popovic
Ramesh Reddy Guggilla
Swati Mishra
Gwenny Cosemans
Lise Tordeurs
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
et al.
C3
Conferentie
2020
Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma
Mina Popovic
Lien Dhaenens
Annekatrien Boel
Björn Menten
Björn Heindryckx
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION UPDATE
2020
Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma (vol 26, pg 313, 2020)
Mina Popovic
Lien Dhaenens
Annekatrien Boel
Björn Menten
Björn Heindryckx
Correctie
2020
Correcting PLCζ mutation in the germ line to overcome transmission of hereditary infertility in mice
Bieke Bekaert
Annekatrien Boel
Vanessa Thys
Panagiotis Stamatiadis
Susana Marina Chuva de Sousa Lopes
Petra De Sutter
John Parrington
Björn Menten
Dominic Stoop
Paul Coucke
et al.
C3
Conferentie
2020
Detection of copy number alterations by shallow whole-genome sequencing of formalin-fixed, paraffin-embedded tumor tissue
Malaïka Van der Linden
Lennart Raman
Ansel Vander Trappen
Annelies Dheedene
Matthias De Smet
Tom Sante
David Creytens
Yolande Lievens
Björn Menten
Jo Van Dorpe
et al.
A1
Artikel in een tijdschrift
in
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
2020
Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest
Maoxing Tang
Mina Popovic
Panagiotis Stamatiadis
Margot Van der Jeught
Rudy Van Coster
Dieter Deforce
Petra De Sutter
Paul Coucke
Björn Menten
Dominic Stoop
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2020
Long noncoding RNA SILC1 is an upstream regulator of SOX11 in neuroblastoma
Amber Louwagie
Bieke Decaesteker
Eva D'haene
Louis Delhaye
Eric de Bony de Lavergne
Christophe Van Neste
Rogier Versteeg
Sara Ek
Björn Menten
Jan Koster
et al.
C3
Conferentie
2020
Mechanistic dissection of chromatin topology disruption in the 5q14.3 MEF2C locus as an indirect driver of neurodevelopmental disorders
Kiana Mohajeri
Eva D'haene
Rachita Yadav
Huiya Gu
Björn Menten
Aviva Presser Aiden
Chelsea Lowther
Serkan Erdin
Erez Lieberman Aiden
James Gusella
et al.
C3
Conferentie
2020
Microcoria due to first duplication of 13q32.1 including the GPR180 gene and maternal mosaicism
Elise Pozza
Hannah Verdin
Hilde Deconinck
Annelies Dheedene
Björn Menten
Elfride De Baere
Irina Balikova
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2020
Prenatally detected copy number variants in a national cohort : a postnatal follow-up study
Joke Muys
Yves Jacquemyn
Bettina Blaumeiser
Laura Bourlard
Nathalie Brison
Saskia Bulk
Patrizia Chiarappa
Anne De Leener
Marjan De Rademaeker
Julie Desir
et al.
A1
Artikel in een tijdschrift
in
PRENATAL DIAGNOSIS
2020
Shallow whole-genome sequencing of cell-free DNA for B-cell lymphoma diagnosis and disease monitoring : a standardized approach with underappreciated potential
Malaïka Van der Linden
Lennart Raman
Ciel De Vriendt
Bliede Van den Broeck
Kristoff Muylle
Dries Deeren
Kathleen Claes
Björn Menten
Fritz Offner
Jo Van Dorpe
C3
Conferentie
2020
Shallow whole-genome sequencing of cell-free DNA for B-cell lymphoma diagnosis and disease monitoring: a standardized approach with underappreciated potential
Malaïka Van der Linden
Lennart Raman
Ciel De Vriendt
Bliede Van den Broeck
Kristoff Muylle
Dries Deeren
Kathleen Claes
Björn Menten
Fritz Offner
Jo Van Dorpe
C3
Conferentie
2020
Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma
Lennart Raman
Malaïka Van der Linden
Kim Van der Eecken
Karim Vermaelen
Ingel Demedts
Veerle Surmont
Ulrike Himpe
Franceska Dedeurwaerdere
Liesbeth Ferdinande
Yolande Lievens
et al.
A1
Artikel in een tijdschrift
in
GENOME MEDICINE
2020
Unraveling complex structural variants of CEP78 leading to cone rod dystrophy and hearing loss using long read sequencing
Giulia Ascari
Nanna D. Rendtorff
Julie De Zaeytijd
Valerie Baumont
Marieke De Bruyne
Mattias Van Heetvelde
Toon Rosseel
Tim De Pooter
Peter De Rijk
Wouter De Coster
et al.
C3
Conferentie
2020
Unraveling complex structural variants of CEP78 leading to cone rod dystrophy and hearing loss using long read sequencing
Giulia Ascari
Nanna D. Rendtorff
Julie De Zaeytijd
Valerie Baumont
Marieke De Bruyne
Mattias Van Heetvelde
Toon Rosseel
Tim De Pooter
Peter De Rijk
Wouter De Coster
et al.
C3
Conferentie
2020
Unraveling complex structural variants of CEP78 leading to cone-rod dystrophy and hearing loss using long-read sequencing
Giulia Ascari
Nanna D. Rendtorff
Julie Jacob
Julie De Zaeytijd
Valerie Baumont
Marieke De Bruyne
Toon Rosseel
Mattias Van Heetvelde
Tim De Pooter
Wouter De Coster
et al.
C3
Conferentie
2020
2019
17q gain provides proliferative advantage to human embryonic stem cells under conditions of replicative stress
Liselot Mus
Geertrui Denecker
Stéphane Van Haver
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2019
17q gain provides proliferative advantage to human embryonic stem cells under replicative stress
Liselot Mus
Stéphane Van Haver
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2019
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation
Simon Tavernier
V Athanasopoulos
PATRICK VERLOO
G Behrens
Jens Staal
Delfien Bogaert
Leslie Naesens
Marieke De Bruyne
Sofie Van Gassen
Eef Parthoens
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2019
A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
HUMAN MOLECULAR GENETICS
2019
A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 gene (ZFHX3)
Eva Jacobs
Sarah Vergult
Maria Palomares Braro
Sixto Garcia-Minaur
S. Simmaro Fernando
T. Duelund Hjortshøj
M. Gérard
A. Molin
P. Villavicencio-Lorini
J. Köhlhase
et al.
C3
Conferentie
2019
Analysis of whole exome sequencing data with a panel of genes associated with intellectual disability and epilepsy in a diagnostic lab
Sarah Vergult
Erika D'haenens
Machteld Baetens
Frauke Coppieters
Maarten De Smet
Annelies Dheedene
Toon Rosseel
Tom Sante
Björn Menten
C3
Conferentie
2019
Circulating cell-free DNA for response evaluation of intravascular lymphoma
Dries Deeren
Malaïka Van der Linden
Franceska Dedeurwaerdere
Lien Deleu
Caressa Meert
Björn Menten
Jo Van Dorpe
A1
Artikel in een tijdschrift
in
ANNALS OF HEMATOLOGY
2019
Clinical experience with shallow whole genome sequencing as a detection method for Copy Number Variations
Björn Menten
Maarten De Smet
Lennart Raman
Tom Sante
Nadine Van Roy
Annelies Dheedene
C3
Conferentie
2019
De novo missense variants in RAC3 cause a novel neurodevelopmental syndrome
Gregory Costain
Bert Callewaert
Heinz Gabriel
Tiong Y Tan
Susan Walker
John Christodoulou
Tamas Lazar
Björn Menten
Julia Orkin
Simon Sadedin
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2019
De novo missense variants in RAC3 cause a novel neurodevelopmental syndrome
M. Osundiji
G. Costain
B. Callewaert
H. Gabriel
T. Y. Tan
S. Walker
Björn Menten
A. Vanlander
S. Vergult
M. Snell
et al.
C3
Conferentie
2019
Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients
Greet Wieme
Frederik Berrevoet
Aude Vanlander
Jo Van Dorpe
Anne Hoorens
Malaïka Van der Linden
Bram Parton
Jurgen van Limmen
ANN DE BRUYNE
Marc De Man
et al.
C3
Conferentie
2019
Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients
Greet Wieme
Frederik Berrevoet
Aude Vanlander
Jo Van Dorpe
Anne Hoorens
Malaïka Van der Linden
Bram Parton
Jurgen van Limmen
ANN DE BRUYNE
Marc De Man
et al.
C3
Conferentie
2019
Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients
Greet Wieme
Frederik Berrevoet
Aude Vanlander
Jo Van Dorpe
Anne Hoorens
Malaïka Van der Linden
Bram Parton
Jurgen van Limmen
ANN DE BRUYNE
Marc De Man
et al.
C3
Conferentie
2019
Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients
Greet Wieme
Frederik Berrevoet
Aude Vanlander
Jo Van Dorpe
Anne Hoorens
Malaïka Van der Linden
Bram Parton
Jurgen van Limmen
ANN DE BRUYNE
Marc De Man
et al.
C3
Conferentie
2019
Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Stéphane Van Haver
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2019
Exploring the potential of shallow whole-genome sequencing for diagnosis and disease monitoring of lymphoma in liquid biopsy
Lennart Raman
Malaïka Van der Linden
Ciel De Vriendt
Bliede Van den Broeck
Kristoff Muylle
Dries Deeren
Björn Menten
Fritz Offner
Jo Van Dorpe
C3
Conferentie
2019
Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsy
Mina Popovic
L. Dhaenens
J. Taelman
Annelies Dheedene
M. Bialecka
Petra De Sutter
S. M. Chuva de Sousa Lopes
Björn Menten
Björn Heindryckx
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2019
Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia
Gayle P Pouliot
James Degar
Laura Hinze
Bose Kochupurakkal
Chau D Vo
Melissa A Burns
Lisa Moreau
Chirag Ganesa
Justine Roderick
Sofie Peirs
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2019
Non-invasive prenatal testing (NIPT) : how to handle secondary findings of maternal chromosomal abnormalities
Machteld Baetens
Tom Sante
Sarah Vergult
M. De Smet
S. Janssens
Olivier Vanakker
Bert Callewaert
Bruce Poppe
Annelies Dheedene
Björn Menten
C3
Conferentie
2019
Noncoding structural variants disrupt the regulatory architecture of Rett genes
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
C3
Conferentie
2019
Noncoding structural variants disrupt the regulatory architecture of Rett genes
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
C3
Conferentie
2019
PCR based target enrichment for variant confirmation, gene panels and multiplex PCR sample tracking in a whole exome sequencing workflow
Frauke Coppieters
Thalia Van Laethem
Matthias De Smet
Paul Coucke
Elfride De Baere
Kathleen Claes
Björn Menten
Jo Vandesompele
Steve Lefever
C3
Conferentie
2019
Preface : in silico pipeline for accurate cell-free fetal DNA fraction prediction
Lennart Raman
Machteld Baetens
Matthias De Smet
Annelies Dheedene
Jo Van Dorpe
Björn Menten
A1
Artikel in een tijdschrift
in
PRENATAL DIAGNOSIS
2019
Preimplantation genetic diagnosis for chromosomal rearrangements using shallow whole genome sequencing at the blastocyst stage
Annelies Dheedene
Ilse De Croo
Etienne Van den Abbeel
Petra De Sutter
Kelly Tilleman
Björn Menten
C3
Conferentie
2019
SOX11 as mediator of the adrenergic cell state in NB
Bieke Decaesteker
Amber Louwagie
Sara De Brouwer
Volodimir Olexiouk
Geertrui Denecker
Carolina de Carvalho Nunes
Karen Verboom
Moritz Gartlgruber
Wouter Van Loocke
Elena Afanasyeva
et al.
C3
Conferentie
2019
SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma
Amber Louwagie
Bieke Decaesteker
Sara De Brouwer
Geertrui Denecker
Carolina de Carvalho Nunes
Volodimir Olexiouk
Karen Verboom
Moritz Gartlgruber
Wouter Van Loocke
Elena Afanasyeva
et al.
C3
Conferentie
2019
SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma
Amber Louwagie
Bieke Decaesteker
Carolina de Carvalho Nunes
Geertrui Denecker
Volodimir Olexiouk
Karen Verboom
Moritz Gartlgruber
Wouter Van Loocke
Elena Afanasyeva
Pauline Depuydt
et al.
C3
Conferentie
2019
Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients
Charlotte Vandeputte
Jolien Van Thorre
Ruben Van Paemel
Andries De Koker
Leen Willems
Jo Van Dorpe
Malaïka Van der Linden
Jilke De Wilde
Björn Menten
L. van Zogchel
et al.
C3
Conferentie
2019
Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients
Charlotte Vandeputte
Jolien Van Thorre
Ruben Van Paemel
Andries De Koker
Leen Willems
Jo Van Dorpe
Malaïka Van der Linden
Jilke De Wilde
Björn Menten
Lieke van Zogchel
et al.
C3
Conferentie
2019
Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients
Charlotte Vandeputte
Jolien Van Thorre
Ruben Van Paemel
Andries De Koker
Leen Willems
Jo Van Dorpe
Malaïka Van der Linden
Jilke De Wilde
Björn Menten
Lieke van Zogchel
et al.
C3
Conferentie
2019
Successful copy number alteration profiling using circulating cell-free tumor DNA as a non-invasive alternative for tissue biopsies in pediatric cancer patients
Charlotte Vandeputte
Jolien Van Thorre
Ruben Van Paemel
Andries De Koker
Leen Willems
Jo Van Dorpe
Malaïka Van der Linden
Jilke De Wilde
Björn Menten
Lieke van Zogchel
et al.
C3
Conferentie
2019
Two novel probands with Myhre syndrome identified through WES
Ilse Meerschaut
Aude Beyens
Wouter Steyaert
Riet De Rycke
Björn Menten
Katrien Bonte
Tine De Backer
Sandra Janssens
Fransiska Malfait
Joseph Panzer
et al.
C3
Conferentie
2019
WNT inhibition and increased fibroblast growth factor signaling promotes derivation of less heterogeneous primed human embryonic stem cells, compatible with differentiation
Jasin Taelman
Mina Popovic
Monika Bialecka
Laurentijn Tilleman
Sharat Warrier
Margot Van der Jeught
Björn Menten
Dieter Deforce
Petra De Sutter
Filip Van Nieuwerburgh
et al.
A1
Artikel in een tijdschrift
in
STEM CELLS AND DEVELOPMENT
2019
WisecondorX : improved copy number detection for routine shallow whole-genome sequencing
Lennart Raman
Annelies Dheedene
Matthias De Smet
Jo Van Dorpe
Björn Menten
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2019
2018
A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
C3
Conferentie
2018
BATCH-GE : batch analysis of next-generation sequencing data for genome editing assessment (vol 6, 30330, 2016)
Annekatrien Boel
Wouter Steyaert
Nina De Rocker
Björn Menten
Bert Callewaert
Anne De Paepe
Paul Coucke
Andy Willaert
Correctie
2018
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Vanlombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conferentie
2018
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Vanlombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conferentie
2018
Chromosomal mosaicism in human blastocysts : the ultimate challenge of preimplantation genetic testing?
Mina Popovic
Annelies Dheedene
CHRISTODOULOS CHRISTODOULOU
Jasin Taelman
Lien Dhaenens
Filip Van Nieuwerburgh
Dieter Deforce
Etienne Van den Abbeel
Petra De Sutter
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2018
Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background
Sabitri Ghimire
Margot Van der Jeught
Jitesh Neupane
Matthias S Roost
Jasper Anckaert
Mina Popovic
Filip Van Nieuwerburgh
Pieter Mestdagh
Jo Vandesompele
Dieter Deforce
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2018
Complex III deficiency due to a homozygous mutation in the nuclear encoded subunit UQCRQ
Rudy Van Coster
Joél Smet
Boel De Paepe
Elise Vantroys
Femke Nachtergaele
Sarah Vergult
Björn Menten
Arnaud Vanlander
François-Guillaume Debray
C3
Conferentie
2018
De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation
M. Felicia Basilicata
Ange-Line Bruel
Giuseppe Semplicio
Claudia Isabelle Keller Valsecchi
Tuğçe Aktaş
Yannis Duffourd
Tobias Rumpf
Jenny Morton
Iben Bache
Witold G. Szymanski
et al.
A1
Artikel in een tijdschrift
in
NATURE GENETICS
2018
Detection of copy number alterations using shallow whole genome sequencing on formalin-fixed paraffin-embedded tumor tissue
Malaïka Van der Linden
Lennart Raman
Ansel Vander Trappen
Annelies Dheedene
Matthias De Smet
Tom Sante
David Creytens
Björn Menten
Jo Van Dorpe
Nadine Van Roy
C3
Conferentie
2018
Detection of copy number alterations using shallow whole genome sequencing on formalin-fixed paraffin-embedded tumor tissue
Malaïka Van der Linden
Lennart Raman
Ansel Vander Trappen
Annelies Dheedene
Matthias De Smet
Tom Sante
David Creytens
Björn Menten
Jo Van Dorpe
Nadine Van Roy
C3
Conferentie
2018
Exploring the contribution of gene dosage effects of 17Q gain on ESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Stéphane Van Haver
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2018
Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Stéphane Van Haver
Nadja Zeltner
Yudelca Ogando
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2018
Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Stéphane Van Haver
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2018
Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation
Liselot Mus
Geertrui Denecker
Nadja Zeltner
Yudelca Ogando
Stéphane Van Haver
Ellen Sanders
Eva Jacobs
Mina Popovic
Christophe Van Neste
Suzanne Vanhauwaert
et al.
C3
Conferentie
2018
Implementation of an in-house designed skeletal dysplasia gene panel as a first screening step to diagnose unsolved osteogenesis imperfecta(-like) patients
Brecht Guillemyn
Delfien Syx
Toon Rosseel
H Kayserlili
AM Cueto-González
L Van Maldergem
Björn Menten
Anne De Paepe
Paul Coucke
Fransiska Malfait
et al.
C3
Conferentie
2018
Leigh syndrome followed by parkinsonism in an adult with homozygous c.626C > T mutation in MTFMT
Dimitri Hemelsoet
Arnaud Vanlander
Joél Smet
Elise Vantroys
Marjan Acou
Ingeborg Goethals
Tom Sante
Sara Seneca
Björn Menten
Rudy Van Coster
A1
Artikel in een tijdschrift
in
NEUROLOGY-GENETICS
2018
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia
Ingrid M Ariës
Kimberly Bodaar
Salmaan A Karim
Triona Ni Chonghaile
Laura Hinze
Melissa A Burns
Maren Pfirrmann
James Degar
Jack T Landrigan
Sebastian Balbach
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXPERIMENTAL MEDICINE
2018
SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components
Bieke Decaesteker
Sara De Brouwer
Geertrui Denecker
Fanny De Vloed
Wouter Van Loocke
Suzanne Vanhauwaert
Pauline Depuydt
Moritz Gartlgruber
Jolien De Wyn
Genevieve Laureys
et al.
C3
Conferentie
2018
Severe hepatopathy and neurological deterioration after start of valproate treatment in a 6-year-old child with mitochondrial tryptophanyl-tRNA synthetase deficiency
Elise Vantroys
Joél Smet
Arnaud Vanlander
Sarah Vergult
Ruth De Bruyne
Frank Roels
Hedwig Stepman
Herbert Roeyers
Björn Menten
Rudy Van Coster
A1
Artikel in een tijdschrift
in
ORPHANET JOURNAL OF RARE DISEASES
2018
Shallow whole genome sequencing allows successful copy number profiling in formalin-fixed paraffin-embedded material in neuroblastoma patients
Charlotte Vandeputte
Ruben Van Paemel
Bram De Wilde
Malaïka Van der Linden
Jo Van Dorpe
Björn Menten
Franki Speleman
Nadine Van Roy
Katleen De Preter
C3
Conferentie
2018
Targeted genomic screen reveals focal long non-coding RNA copy number alterations in cancer cell lines
Pieter-Jan Volders
Steve Lefever
Shalina Baute
Justine Nuytens
Katrien Vanderheyden
Björn Menten
Pieter Mestdagh
Jo Vandesompele
A2
Artikel in een tijdschrift
in
NON-CODING RNA
2018
The Belgian MicroArray Prenatal (BEMAPRE) database : a systematic nationwide repository of fetal genomic aberrations
Joke Muys
Bettina Blaumeiser
Yves Jacquemyn
Claude Bandelier
Nathalie Brison
Saskia Bulk
Patrizia Chiarappa
Winnie Courtens
Anne De Leener
Marjan De Rademaeker
et al.
A1
Artikel in een tijdschrift
in
PRENATAL DIAGNOSIS
2018
The MEF2C regulatory network is disrupted in patients with Rett-like characteristics
Eva D'haene
Sarah Vergult
Reut Bar-Yaakov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Reut Eshel
Rowan Alatawna
Ramon Birnbaum
et al.
C3
Conferentie
2018
The MEF2C regulatory network is disrupted in patients with Rett-like characteristics
Eva D'haene
Reut Bar-Yaakov
Inbar Bariah
Sien Van Loo
Lies Vantomme
Francisco Avila Cobos
Reut Eshel
Rowan Alatawna
Björn Menten
Ramon Birnbaum
et al.
C3
Conferentie
2018
The clinical heterogeneity of the NARS2 c.822G>C mutation clearly illustrated in two siblings : epilepsy and myopathy
Arnaud Vanlander
Helene Verhelst
Elise Vantroys
Joél Smet
Boel De Paepe
Sarah Vergult
Björn Menten
Rudy Van Coster
C3
Conferentie
2018
The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease
Bram De Wilde
Anneleen Beckers
Sven Lindner
Kristina Althoff
Katleen De Preter
Pauline Depuydt
Pieter Mestdagh
Tom Sante
Steve Lefever
Falk Hertwig
et al.
A2
Artikel in een tijdschrift
in
ONCOTARGET
2018
The neuroblastoma-specific lncRNA NESPR activates PHOX2B expression and is essential for neuroblastoma cell survival
Dries Rombaut
Tiago França Brazao
Louis Delhaye
Eva D'haene
Giorgio Milazzo
Roberto Ciaccio
Nurten Yigit
Celine Everaert
Matthias Fischer
Thorsten Simon
et al.
C3
Conferentie
2018
2017
CRISPR/Cas9-mediated genome editing in naive human embryonic stem cells followed by neural differentiation : an optimized workflow
Eva Jacobs
Sharrat Warrier
Eva D'haene
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conferentie
2017
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Van Lombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2017
Comprehensive comparison of inner cell mass and trophectoderm reveals the complex nature of chromosomal mosaicism in human embryos
Mina Popovic
Annelies Dheedene
CHRISTODOULOS CHRISTODOULOU
Margot Van der Jeught
Filip Van Nieuwerburgh
Dieter Deforce
Petra De Sutter
Etienne Van den Abbeel
Björn Menten
Björn Heindryckx
C3
Conferentie
2017
Confirmation of an ARID2 defect in SWI/SNF-related intellectual disability
Ruben Van Paemel
Pauline De Bruyne
Saskia van der Straaten
Marleen D'Hondt
Urlien Fränkel
Annelies Dheedene
Björn Menten
Bert Callewaert
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2017
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Laurentijn Tilleman
Ella Sutherland
Jasin Taelman
Mina Popovic
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2017
FOXP1-related intellectual disability syndrome : a recognisable entity
Ilse Meerschaut
Daniel Rochefort
Nicole Revençu
Justine Pètre
Christina Corsello
Guy A Rouleau
Fadi F Hamdan
Jacques L Michaud
Jenny Morton
Jessica Radley
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2017
Fertility in Trans Persons
Chloë De Roo
Justine Defreyne
Petra De Sutter
Kelly Tilleman
Joz Motmans
Boudewijn Kreukels
Björn Menten
Guy T'Sjoen
Nora van Mello
C3
Conferentie
2017
Innovations in cytogenomic technologies for prenatal diagnosis
Annelies Dheedene
Björn Menten
Sarah Vergult
Proefschrift
2017
Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly
Daniela A Braun
Jia Rao
Geraldine Mollet
David Schapiro
Marie-Claire Daugeron
Weizhen Tan
Olivier Gribouval
Olivia Boyer
Patrick Revy
Tilman Jobst-Schwan
et al.
A1
Artikel in een tijdschrift
in
NATURE GENETICS
2017
NR4A2 causes an autism spectrum disorder
Helene Verhelst
Patrick Verloo
Annelies Dheedene
Bert Callewaert
Björn Menten
C3
Conferentie
2017
New insights into the phenotype of FARS2 deficiency
Elise Vantroys
Austin Larson
Marisa Friederich
Kaz Knight
Michael A Swanson
Christopher A Powell
Joél Smet
Sarah Vergult
Boel De Paepe
Sara Seneca
et al.
A1
Artikel in een tijdschrift
in
MOLECULAR GENETICS AND METABOLISM
2017
Pancreatic cancer : hope to improve prognosis through thorough analysis of DNA and RNA biomarkers for detection and therapy monitoring in liquid biopsies
Greet Wieme
Frederik Berrevoet
Aude Vanlander
Marc De Man
Karen Geboes
Jo Van Dorpe
Anne Hoorens
Malaïka Van der Linden
Jurgen van Limmen
ANN DE BRUYNE
et al.
C3
Conferentie
2017
Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage
CHRISTODOULOS CHRISTODOULOU
Annelies Dheedene
Björn Heindryckx
Filip Van Nieuwerburgh
Dieter Deforce
Petra De Sutter
Björn Menten
Etienne Van den Abbeel
A1
Artikel in een tijdschrift
in
FERTILITY AND STERILITY
2017
SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma
Bieke Decaesteker
Sara De Brouwer
Fanny De Vloed
Geertrui Denecker
Suzanne Vanhauwaert
Jolien De Wyn
Genevieve Laureys
Björn Menten
Pauline Depuydt
Patrick Reynolds
et al.
C3
Conferentie
2017
SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma
Bieke Decaesteker
Sara De Brouwer
Fanny De Vloed
Geertrui Denecker
Suzanne Vanhauwaert
Jolien De Wyn
Genevieve Laureys
Björn Menten
Pauline Depuydt
Jo Vandorpe
et al.
C3
Conferentie
2017
Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients
Nadine Van Roy
Malaïka Van der Linden
Pauline Depuydt
Björn Menten
Annelies Dheedene
Charlotte Vandeputte
Jo Van Dorpe
Genevieve Laureys
Marjolijn Renard
Tom Sante
et al.
C3
Conferentie
2017
Shallow whole genome sequencing on circulating cell-free DNA allows reliable noninvasive copy-number profiling in neuroblastoma patients
Nadine Van Roy
Malaïka Van der Linden
Björn Menten
Annelies Dheedene
Charlotte Vandeputte
Jo Van Dorpe
Genevieve Laureys
Marleen Renard
Tom Sante
Tim Lammens
et al.
A1
Artikel in een tijdschrift
in
CLINICAL CANCER RESEARCH
2017
The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies
Claire Redin
Harrison Brand
Ryan L Collins
Tammy Kammin
Elyse Mitchell
Jennelle C Hodge
Carrie Hanscom
Vamsee Pillalamarri
Catarina M Seabra
Mary-Alice Abbott
et al.
A1
Artikel in een tijdschrift
in
NATURE GENETICS
2017
arrEYE : a customized platform for high-resolution copy number analysis of coding and noncoding regions of known and candidate retinal dystrophy genes and retinal noncoding RNAs
Caroline Van Cauwenbergh
Kristof Van Schil
Robrecht Cannoodt
Miriam Bauwens
Thalia Van Laethem
Sarah De Jaegere
Wouter Steyaert
Tom Sante
Björn Menten
Bart Leroy
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2017
2016
BATCH-GE : batch analysis of next-generation sequencing data for genome editing assessment
Annekatrien Boel
Wouter Steyaert
Nina De Rocker
Björn Menten
Bert Callewaert
Anne De Paepe
Paul Coucke
Andy Willaert
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
CRISPR-Cas9 modeling of cell lines and zebrafish to study the TLX1-PHF6 cooperative interrelationship in T-cell acute lymphoblastic leukemia
Siebe Loontiens
Kaat Durinck
Nina De Rocker
Annekatrien Boel
Els Janssens
Suzanne Vanhauwaert
Pieter Rondou
Charles De Bock
Inge Van de Walle
Finola Moore
et al.
C3
Conferentie
2016
CRISPR/Cas9-mediated genome editing in naive human embryonic stem cells : an optimized workflow
Eva Jacobs
Sharrat Warrier
Eva D'haene
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conferentie
2016
Charcot-Marie-Tooth disease type 2G redefined by a novel mutation in LRSAM1
Kristien Peeters
Paulius Palaima
Ana L Pelayo-Negro
Antonio García
Elena Gallardo
Rosario García-Barredo
Ligia Mateiu
Jonathan Baets
Björn Menten
Els De Vriendt
et al.
A1
Artikel in een tijdschrift
in
ANNALS OF NEUROLOGY
2016
Combined OXPHOS deficiencies caused by defects in transcription or translation due to nuclear gene dysfunctions and pharmacological compounds
Arnaud Vanlander
Rudy Van Coster
Björn Menten
Proefschrift
2016
Detection of copy number aberrations in cell free DNA from plasma of neuroblastoma patients using shallow massive parallel sequencing
Katleen De Preter
Nadine Van Roy
Björn Menten
Annelies Dheedene
Genevieve Laureys
Bram De Wilde
Franki Speleman
C3
Conferentie
2016
Development of a blood test for selection of lung cancer patients who could benefit from immunotherapy.
Malaïka Van der Linden
Karim Vermaelen
Ingel Demedts
Veerle Surmont
Kathleen Claes
Björn Menten
Jo Van Dorpe
C3
Conferentie
2016
Elucidating the role of coding and noncoding genes in neuronal development using human embryonic stem cells and the CRISPR/Cas9 system
Eva Jacobs
Sharat Warrier
Eva Van Lombergen
Eva D'haene
Margot Van der Jeught
Björn Heindryckx
Sarah Vergult
Björn Menten
C3
Conferentie
2016
FOXP1-related intellectual disability syndrome : a recognizable entity
Ilse Meerschaut
J Pètre
N Revencu
NELE BOCKAERT
Ann Oostra
Olivier Vanakker
M Velinov
TJ de Ravel
D Mekahli
KK Vaux
et al.
C3
Conferentie
2016
Flexible analysis of digital PCR experiments using generalized linear mixed models
Matthijs Vynck
Jo Vandesompele
Nele Nijs
Björn Menten
Ariane De Ganck
Olivier Thas
A2
Artikel in een tijdschrift
in
BIOMOLECULAR DETECTION AND QUANTIFICATION
2016
Identification of lncRNAs involved in neuronal differentiation and intellectual disability
Eva D'haene
Eva Jacobs
Pieter-Jan Volders
Björn Menten
Sarah Vergult
C3
Conferentie
2016
Identification of long non-coding RNAs in neuronal development and intellectual disability
Eva D'haene
Eva Jacobs
Pieter-Jan Volders
Björn Menten
Sarah Vergult
C3
Conferentie
2016
Identification of long non-coding RNAs involved in neuronal development and intellectual disability
Eva D'haene
Eva Jacobs
Pieter-Jan Volders
Tim De Meyer
Björn Menten
Sarah Vergult
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
Identification of long non-coding RNAs involved in neuronal development and intellectual disability
Eva D'haene
Eva Jacobs
Pieter-Jan Volders
Tim De Meyer
Björn Menten
Sarah Vergult
C3
Conferentie
2016
Implementation of non-invasive prenatal testing by semiconductor sequencing in a genetic laboratory
Annelies Dheedene
Tom Sante
Matthias De Smet
Jean-François Vanbellinghen
Bernard Grisart
Sarah Vergult
Sandra Janssens
Björn Menten
A1
Artikel in een tijdschrift
in
PRENATAL DIAGNOSIS
2016
Massive parallel sequencing uncovers chromosomal mosaicism in human embryonic stem cells in both primed and naive culture conditions
Mina Popovic
Margot Van der Jeught
Franki Speleman
Filip Van Nieuwerburgh
Petra De Sutter
Björn Menten
Björn Heindryckx
C3
Conferentie
2016
Mild early epileptic encephalopathy evolving to spastic paraplegia, neurogenic bladder and generalized slow colon transit in an 18-year old patient with pathogenic mutations in FARS2
Elise Vantroys
Joél Smet
Arnaud Vanlander
Boel De Paepe
Sarah Vergult
Tom Sante
Björn Menten
Rudy Van Coster
C3
Conferentie
2016
Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins
Przemyslaw Szafranski
Tomasz Gambin
Avinash V Dharmadhikari
Kadir Caner Akdemir
Shalini N Jhangiani
Jennifer Schuette
Nihal Godiwala
Svetlana A Yatsenko
Jessica Sebastian
Suneeta Madan-Khetarpal
et al.
A1
Artikel in een tijdschrift
in
HUMAN GENETICS
2016
Pathogenic mutations in FARS2 in a patient with motor regression and epilepsy as first signs, later evolving to spastic paraplegia associated with autonomic disturbances
Elise Vantroys
Joél Smet
Arnaud Vanlander
Boel De Paepe
Sarah Vergult
Tom Sante
Björn Menten
Rudy Van Coster
C3
Conferentie
2016
Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing
Lieselot Deleye
Dieter De Coninck
Annelies Dheedene
Petra De Sutter
Björn Menten
Dieter Deforce
Filip Van Nieuwerburgh
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
Preimplantation genetic diagnosis (PGD) for translocation carriers using whole genome screening by microarray analysis at the blastocyst stage
CHRISTODOULOS CHRISTODOULOU
Annelies Dheedene
Ilse De Croo
Björn Heindryckx
Lieselot Deleye
Filip Van Nieuwerburgh
Dieter Deforce
Petra De Sutter
Björn Menten
Etienne Van den Abbeel
C3
Conferentie
2016
Profiling of conserved non-coding elements upstream of SHOX and functional characterisation of the SHOX cis-regulatory landscape
Hannah Verdin
Ana Fernández-Miñán
Sara Benito-Sanz
Sandra Janssens
Bert Callewaert
KATHLEEN DE WAELE
Jean De Schepper
Inge François
Björn Menten
Karen Heath
et al.
C3
Conferentie
2016
RC3H1 mutation with increased ICOS expression causes an autoinflammatory syndrome
Filomeen Haerynck
PATRICK VERLOO
Delfien Bogaert
Joél Smet
Arnaud Vanlander
Maria Bordon Cueto De Braem
Helene Verhelst
Rudy Van Coster
Björn Menten
Melissa Dullaers
C3
Conferentie
2016
Subcomplexes of complex V in a patient with Perrault syndrome due to pathogenic mutations in C10orf2
PATRICK VERLOO
Joél Smet
Elise Vantroys
Arnaud Vanlander
Sarah Vergult
Tom Sante
Björn Menten
Rudy Van Coster
C3
Conferentie
2016
The genomic region encompassing the overlapping SOX11 and Lnc-SOX11-1:1 loci exhibits a complex DNA copy number and mRNA expression pattern
Bieke Decaesteker
Sara De Brouwer
Robrecht Cannoodt
Dries Rombaut
Wouter Van Loocke
Annelies Fieuw
Fanny De Vloed
Pieter-Jan Volders
Björn Menten
Rogier Versteeg
et al.
C3
Conferentie
2016
Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Jasin Taelman
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
et al.
C3
Conferentie
2016
Zebrafish collagen type I: molecular and biochemical characterization of the major structural protein in bone and skin
Charlotte Gistelinck
R Gioia
A Gagliardi
F Tonelli
L Marchese
L Bianchi
C Landi
L Bini
Ann Huysseune
Paul Eckhard Witten
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
2015
Alternative routes to induce naive pluripotency in human embryonic stem cells
Galbha Duggal
Sharat Warrier
Sabitri Ghimire
Dorien Broekaert
Margot Van der Jeught
Sylvie Lierman
Tom Deroo
Luc Peelman
Ann Van Soom
Maria Cornelissen
et al.
A1
Artikel in een tijdschrift
in
STEM CELLS
2015
CRISPR/Cas9-mediated genome editing in primed versus naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Eva D'haene
Filip Matthijssens
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conferentie
2015
Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells
Sharat Warrier
Galbha Duggal
Jasin Taelman
Sylvie Lierman
S Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
Björn Menten
et al.
C3
Conferentie
2015
Development of a sequence analysis pipeline for variant detection and interpretation
Tom Sante
Björn Menten
Proefschrift
2015
Genomic aberrations of the CACNA2D1 gene in three patients with epilepsy and intellectual disability
Sarah Vergult
Annelies Dheedene
Alfred Meurs
Franny Faes
Bertrand Isidor
Sandra Janssens
Agnès Gautier
Cédric Le Caignec
Björn Menten
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2015
Identification of lncRNAs involved in neuronal development and intellectual disability
Sarah Vergult
Eva D'haene
Eva Jacobs
Björn Menten
C3
Conferentie
2015
In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis
Stijn Vanhee
Katrien De Mulder
Yasmine Van Caeneghem
Greet Verstichel
Nadine Van Roy
Björn Menten
Imke Velghe
Jan Philippé
Dominique De Bleser
Bart Lambrecht
et al.
A1
Artikel in een tijdschrift
in
HAEMATOLOGICA
2015
Phenotypic and molecular insights into CASK-related disorders in males
Ute Moog
Tatjana Bierhals
Kristina Brand
Jan Bautsch
Saskia Biskup
Thomas Brune
Jonas Denecke
Christine E de Die-Smulders
Christina Evers
Maja Hempel
et al.
A1
Artikel in een tijdschrift
in
ORPHANET JOURNAL OF RARE DISEASES
2015
Profiling of conserved non-coding elements upstream of SHOX and functional characterisation of the SHOX cis-regulatory landscape
Hannah Verdin
Ana Fernández-Miñán
Sara Benito-Sanz
Sandra Janssens
Bert Callewaert
KATHLEEN DE WAELE
Jean De Schepper
Inge François
Björn Menten
Karen E Heath
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2015
Profiling of upstream enhancers and chromatin conformation of the SHOX CIS-regulatory landscape
Hannah Verdin
Ana Fernández-Miñán
Sara Benito-Sanz
Sandra Janssens
Bert Callewaert
KATHLEEN DE WAELE
Jean De Schepper
Inge François
Björn Menten
Karen Heath
et al.
C3
Conferentie
2015
Profiling of upstream enhancers and chromatin conformation of the SHOX CIS-regulatory landscape.
Hannah Verdin
Ana Fernández-Miñán
Sara Benito-Sanz
Sandra Janssens
Bert Callewaert
KATHLEEN DE WAELE
Jean De Schepper
Inge François
Björn Menten
José Luis Gómez-Skarmeta
et al.
C3
Conferentie
2015
Redefining the MED13L syndrome
Abidemi Adegbola
Luciana Musante
Bert Callewaert
Patricia Maciel
Hao Hu
Bertrand Isidor
Sylvie Picker-Minh
Cedric Le Caignec
Barbara Delle Chiaie
Olivier Vanakker
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2015
Refinement of the critical 2p25.3 deletion region: the role of MYT1L in intellectual disability and obesity
Nina De Rocker
Sarah Vergult
David Koolen
Eva Jacobs
Alexander Hoischen
Susan Zeesman
Birgitte Bang
Frédérique Béna
Nele Bockaert
Ernie Bongers
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2015
Selection of lncRNAs involved in neuronal development and intellectual disability
Sarah Vergult
Eva D'haene
Eva Jacobs
Björn Menten
C3
Conferentie
2015
Selection of lncRNAs involved in neuronal development and intellectual disability
Sarah Vergult
Eva D'haene
Eva Jacobs
Björn Menten
C3
Conferentie
2015
Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts
Lieselot Deleye
Annelies Dheedene
Dieter De Coninck
Tom Sante
CHRISTODOULOS CHRISTODOULOU
Björn Heindryckx
Etienne Van den Abbeel
Petra De Sutter
Dieter Deforce
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
FERTILITY AND STERILITY
2015
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Joni Van der Meulen
Viraj Sanghvi
Konstantinos Mavrakis
Kaat Durinck
Fang Fang
Filip Matthijssens
Pieter Rondou
Monica Rosen
Tim Pieters
Peter Vandenberghe
et al.
A1
Artikel in een tijdschrift
in
BLOOD
2015
Two siblings with homozygous pathogenic splice-site variant in mitochondrial asparaginyl-tRNA synthetase (NARS2)
Arnaud Vanlander
Björn Menten
Joél Smet
Linda De Meirleir
Tom Sante
Boel De Paepe
Sara Seneca
Sarah F Pearce
Christopher A Powell
Sarah Vergult
et al.
A1
Artikel in een tijdschrift
in
HUMAN MUTATION
2015
Whole genome amplification with SurePlex results in better copy number alteration detection using sequencing data compared to the MALBAC method
Lieselot Deleye
Dieter De Coninck
CHRISTODOULOS CHRISTODOULOU
Tom Sante
Annelies Dheedene
Björn Heindryckx
Etienne Van den Abbeel
Petra De Sutter
Björn Menten
Dieter Deforce
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2015
2014
3q27.3 microdeletional syndrome: a recognisable clinical entity associating dysmorphic features, marfanoid habitus, intellectual disability and psychosis with mood disorder
Julien Thevenon
Patrick Callier
Hélène Poquet
Iben Bache
Björn Menten
Valérie Malan
Maria Luigia Cavaliere
Jean-Paul Girod
Christel Thauvin-Robinet
Salima El Chehadeh
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2014
A de novo POU3F3 deletion in a boy with intellectual disability and dysmorphic features
Annelies Dheedene
MICHAELA MAES
Sarah Vergult
Björn Menten
A2
Artikel in een tijdschrift
in
MOLECULAR SYNDROMOLOGY
2014
A prospective study of the clinical utility of prenatal chromosomal microarray analysis in fetuses with ultrasound abnormalities and an exploration of a framework for reporting unclassified variants and risk factors
Paul Daniel Brady
BARBARA DELLE CHIAIE
Gabrielle Christenhusz
Kris Dierickx
Kris Van Den Bogaert
Björn Menten
Sandra Janssens
Paul Defoort
Ellen Roets
ELKE SLEURS
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2014
Deletions in 14q24.1q24.3 are associated with congenital heart defects, brachydactyly, and mild intellectual disability
Barbara Oehl-Jaschkowitz
Olivier Vanakker
Anne De Paepe
Björn Menten
Thomas Martin
Georg Weber
Alexander Christmann
Romain Krier
Simone Scheid
Susan E McNerlan
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2014
Extensive clinical, hormonal and genetic screening in a large consecutive series of 46, XY neonates and infants with atypical sexual development
Dorien Baetens
Wilhelm Mladenov
BARBARA DELLE CHIAIE
Björn Menten
An Desloovere
Violeta Iotova
Bert Callewaert
Erik Van Laecke
Piet Hoebeke
Elfride De Baere
et al.
A1
Artikel in een tijdschrift
in
ORPHANET JOURNAL OF RARE DISEASES
2014
Genomic and functional overlap between somatic and germline chromosomal rearrangements
Sebastiaan van Heesch
Marieke Simonis
Markus J van Roosmalen
Vamsee Pillalamarri
Harrison Brand
Ewart W Kuijk
Kim L de Luca
Nico Lansu
A Koen Braat
Androniki Menelaou
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS
2014
Implementation of genomic arrays in prenatal diagnosis: the Belgian approach to meet the challenges
Olivier Vanakker
Catheline Vilain
Katrien Janssens
Nathalie Van der Aa
Guillaume Smits
Claude Bandelier
Bettina Blaumeiser
Saskia Bulk
Jean-Hubert Caberg
Anne De Leener
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2014
In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis
Stijn Vanhee
Katrien De Mulder
Yasmine Van Caeneghem
Nadine Van Roy
Björn Menten
Imke Velghe
Jan Philippé
Tom Taghon
Georges Leclercq
Tessa Kerre
et al.
C3
Conferentie
2014
Mate pair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations
Sarah Vergult
Ellen Van Binsbergen
Tom Sante
Silke Nowak
Olivier Vanakker
Kathleen Claes
Bruce Poppe
Nathalie Van der Aa
Markus J van Roosmalen
Karen Duran
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2014
Mutations affecting the SAND domain of DEAF1 cause intellectual disability with severe speech impairment and behavioral problems
Anneke T Vulto-van Silfhout
Shivakumar Rajamanickam
Philip J Jensik
Sarah Vergult
Nina De Rocker
Kathryn J Newhall
Ramya Raghavan
Sara N Reardon
Kelsey Jarrett
Tara McIntyre
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF HUMAN GENETICS
2014
Mutations in GTPBP3 cause a mitochondrial translation defect associated with hypertrophic cardiomyopathy, lactic acidosis, and encephalopathy
Robert Kopajtich
Thomas J Nicholls
Joanna Rorbach
Metodi D Metodiev
Peter Freisinger
Hanna Mandel
Arnaud Vanlander
Daniele Ghezzi
Rosalba Carrozzo
Robert W Taylor
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF HUMAN GENETICS
2014
Study of the regulatory landscape of SHOX in 503 LWD and ISS cases uncovers a key role of the upstream cis-regulatory element CNE-3
Hannah Verdin
Ana Fernández-Miñán
Kim De Leeneer
Liza Borms
Sandra Janssens
Bert Callewaert
Fransiska Malfait
Ariana Kariminejad
KATHLEEN DE WAELE
Inge François
et al.
C3
Conferentie
2014
Two siblings with myopathy, mild mental retardation and combined OXPHOS deficiencies caused by a mutation in the gene encoding asparaginyl tRNA synthetase, NARS2
Arnaud Vanlander
M Minczuk
Tom Sante
Joél Smet
Boel De Paepe
Linda De Meirleir
Björn Menten
Rudy Van Coster
C3
Conferentie
2014
ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation
Tom Sante
Sarah Vergult
Pieter-Jan Volders
Wigard P Kloosterman
Geert Trooskens
Katleen De Preter
Annelies Dheedene
Franki Speleman
Tim De Meyer
Björn Menten
A1
Artikel in een tijdschrift
in
PLOS ONE
2014
2013
A link between host plant adaptation and pesticide resistance in the polyphagous spider mite Tetranychus urticae
Wannes Dermauw
Nicky Wybouw
Stephane Rombauts
Björn Menten
John Vontas
Miodrag Grbić
Richard M Clark
René Feyereisen
Thomas Van Leeuwen
A1
Artikel in een tijdschrift
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2013
CMYB expression during human in vitro hematopoiesis
Stijn Vanhee
Yasmine Van Caeneghem
Katrien De Mulder
Imke Velghe
Sylvie Taveirne
Nadine Van Roy
Björn Menten
SYLVIA SNAUWAERT
Greet Verstichel
Melissa Dullaers
et al.
C3
Conferentie
2013
Complex genetics of radial ray deficiencies: screening of a cohort of 54 patients
Sarah Vergult
A Jeannette M Hoogeboom
Emilia K Bijlsma
Tom Sante
Eva Klopocki
Bram De Wilde
Marjolijn Jongmans
Christian Thiel
Joke BGM Verheij
Antonio Perez-Aytes
et al.
A1
Artikel in een tijdschrift
in
GENETICS IN MEDICINE
2013
Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus
Gea Beunders
Els Voorhoeve
Christelle Golzio
Luba M Pardo
Jill A Rosenfeld
Michael E Talkowski
Ingrid Simonic
Anath C Lionel
Sarah Vergult
Robert E Pyatt
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF HUMAN GENETICS
2013
Familial cases of a submicroscopic Xp22.2 deletion : genotype-phenotype correlation in microphthalmia with linear skin defects syndrome
Sarah Vergult
Bart Leroy
Ilse Claerhout
Björn Menten
A1
Artikel in een tijdschrift
in
MOLECULAR VISION
2013
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes
Candy Kumps
Annelies Fieuw
Pieter Mestdagh
Björn Menten
Steve Lefever
Filip Pattyn
Sara De Brouwer
Tom Sante
Johannes Hubertus Schulte
Alexander Schramm
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2013
LNCipedia : a database for annotated human lncRNA transcript sequences and structures
Pieter-Jan Volders
Kenny Helsens
Xiaowei Wang
Björn Menten
Lennart Martens
Kris Gevaert
Jo Vandesompele
Pieter Mestdagh
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2013
Matepair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations
Sarah Vergult
Ellen Van Binsbergen
Tom Sante
Silke Nowak
Olivier Vanakker
Kathleen Claes
Bruce Poppe
Nathalie Van der Aa
MJ Van Roosmalen
K Duran
et al.
C3
Conferentie
2013
Microhomology-mediated mechanisms underlie non-recurrent disease-causing microdeletions of the FOXL2 gene or its regulatory domain
Hannah Verdin
Barbara D'haene
DIANE BEYSEN
Yana Novikova
Björn Menten
Tom Sante
Pablo Lapunzina
Julian Nevado
Claudio MB Carvalho
James R Lupski
et al.
A1
Artikel in een tijdschrift
in
PLOS GENETICS
2013
Mitotic microhomology-mediated replication-based mechanisms underlie non-recurrent pathogenic microdeletions of the FOXL2 gene or its regulatory domain
Hannah Verdin
Barbara D'haene
DIANE BEYSEN
Yana Novikova
Björn Menten
Tom Sante
Pablo Lapunzina
Julian Nevado
Claudia Carvalho
James Lupski
et al.
C3
Conferentie
2013
2012
17q24.2 microdeletions: a new syndromal entity with intellectual disability, truncal obesity, mood swings and hallucinations
Sarah Vergult
Andrew Dauber
BARBARA DELLE CHIAIE
Elke Van Oudenhove
Marleen Simon
Ali Rihani
Bart Loeys
Joel Hirschhorn
Jean Pfotenhauer
John A Phillips
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2012
Array comparative genomic hybridization in male infertility
K Stouffs
D Vandermaelen
A Massart
Björn Menten
Sarah Vergult
H Tournaye
W Lissens
A1
Artikel in een tijdschrift
in
HUMAN REPRODUCTION
2012
BDNF and DYRK1A are variable and inversely correlated in lymphoblastoid cell lines from Down syndrome patients
Asma Tlili
Alexander Hoischen
Clémentine Ripoll
Eva Benabou
Anne Badel
Anne Ronan
Renaud Touraine
Yann Grattau
Samantha Stora
Bregje van Bon
et al.
A1
Artikel in een tijdschrift
in
MOLECULAR NEUROBIOLOGY
2012
Complex genetics of radial ray deficiencies: screening of a cohort of 54 patients
Sarah Vergult
Jeanette Hoogeboom
EK Bijlsma
Tom Sante
Eva Klopocki
Bram De Wilde
Marjolein Jongmans
Christian Thiel
J Verheij
A Perez-Aytes
et al.
C3
Conferentie
2012
Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms
Wigard P Kloosterman
Masoumeh Tavakoli-Yaraki
Markus J van Roosmalen
Ellen van Binsbergen
Ivo Renkens
Karen Duran
Lucia Ballarati
Sarah Vergult
Daniel Giardino
Kerstin Hansson
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS
2012
Genomic structural variation in patients with intellectual disability and congenital anomalies
Sarah Vergult
Björn Menten
Geert Mortier
Proefschrift
2012
Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas
Annelies Fieuw
Candy Kumps
Alexander Schramm
Filip Pattyn
Björn Menten
Francesca Antonacci
Peter Sudmant
Johannes H Schulte
Nadine Van Roy
Sarah Vergult
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF CANCER
2012
Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization
Mado Vandewoestyne
Candy Kumps
Katrien Swerts
Björn Menten
Tim Lammens
Jan Philippé
Katleen De Preter
Genevieve Laureys
Nadine Van Roy
Franki Speleman
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF CANCER
2012
Large-scale and targeted genomic screen reveals focal lncRNA copy number alterations in cancer cells
Pieter-Jan Volders
Pieter Mestdagh
Björn Menten
Jo Vandesompele
C3
Conferentie
2012
Matepair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations
Sarah Vergult
Ellen Van Binsbergen
Tom Sante
Silke Nowak
Olivier Vanakker
Kathleen Claes
Bruce Poppe
Nathalie Van der Aa
MJ Van Roosmalen
K Duran
et al.
C3
Conferentie
2012
Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes
Wen Li
Xianming Wang
Wenxia Fan
Ping Zhao
Yau-Chi Chan
Shen Chen
Shiqiang Zhang
Xiangpeng Guo
Ya Zhang
Yanhua Li
et al.
A1
Artikel in een tijdschrift
in
HUMAN MOLECULAR GENETICS
2012
Nasal speech in patients with 12q15 microdeletions
Sarah Vergult
Danijela Krgovic
Bart Loeys
Stanislas Lyonnet
Agne Liedén
Britt-Marie Anderlid
Freddie Sharkey
Shelagh Joss
Geert Mortier
Björn Menten
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2012
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
Lukas C Heukamp
Theresa Thor
Alexander Schramm
Katleen De Preter
Candy Kumps
Bram De Wilde
Andrea Odersky
Martin Peifer
Sven Lindner
Annika Spruessel
et al.
A1
Artikel in een tijdschrift
in
SCIENCE TRANSLATIONAL MEDICINE
2012
2011
4q34.1-q35.2 deletion in a boy with phenotype resembling 22q11.2 deletion syndrome
Goran Cuturilo
Björn Menten
Aleksandar Krstic
Danijela Drakulic
Ida Jovanovic
Vojislav Parezanovic
Milena Stevanovic
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2011
A visualization platform for interpretation of structural genomic data
Tom Sante
Sarah Vergult
Björn Menten
C3
Conferentie
2011
Anti-NMDA-receptor encephalitis in a 3 year old patient with chromosome 6p21.32 microdeletion including the HLA cluster
Helene Verhelst
PATRICK VERLOO
Karlien Dhondt
Boel De Paepe
Björn Menten
Josep Dalmau
Rudy Van Coster
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
2011
Applying massive parallel sequencing to molecular diagnosis of Marfan and Loeys-Dietz syndromes
Machteld Baetens
Lut Van Laer
Kim De Leeneer
Jan Hellemans
Joachim De Schrijver
Hendrik Van de Voorde
Marjolijn Renard
Hal Dietz
Ronald V Lacro
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
HUMAN MUTATION
2011
Complex genetics of radial ray deficiencies: screening of a cohort of 50 patients
Sarah Vergult
Jeanette Hoogeboom
EK Bijlsma
Tom Sante
Eva Klopocki
Bram De Wilde
Marjolein Jongmans
Christian Thiel
J Verheij
A Perez-Aytes
et al.
C3
Conferentie
2011
Expanding the spectrum of FOXC1 and PITX2 mutations and copy number changes in patients with anterior segment malformations
Barbara D'haene
Françoise Meire
Ilse Claerhout
Hester Y Kroes
Astrid Plomp
Yvonne H Arens
Thomy de Ravel
Ingele Casteels
Sarah De Jaegere
Sally Hooghe
et al.
A1
Artikel in een tijdschrift
in
INVESTIGATIVE OPHTHALMOLOGY
2011
Genomic microarrays: challenges and opportunities: five years experience in a diagnostic setting
Sarah Vergult
Karen Buysse
BARBARA DELLE CHIAIE
Sandra Janssens
Olivier Vanakker
Rudy Van Coster
Anne De Paepe
Franki Speleman
Björn Menten
C3
Conferentie
2011
High-resolution breakpoint mapping of 10 regulatory and 32 FOXL2 encompassing deletions in BPES using targeted microarrays
Hannah Verdin
Barbara D'haene
Yana Novikova
Pablo Lapunzina
Julian Nevado
Björn Menten
Elfride De Baere
C3
Conferentie
2011
High-resolution breakpoint mapping of 38 regulatory and FOXL2 encompassing deletions in BPES using targeted microarrays
Hannah Verdin
Barbara D'haene
Yana Novikova
Pablo Lapunzina
Julian Nevado
Björn Menten
Elfride De Baere
C3
Conferentie
2011
High-resolution breakpoint mapping of 38 regulatory and FOXL2 encompassing deletions in BPES using targeted microarrays
Hannah Verdin
Barbara D'haene
Pablo Lapunzina
Julian Nevado
Björn Menten
Elfride De Baere
C3
Conferentie
2011
Identification of a new rare recurrent 1q42.2-qter deletion in neuroblastoma
Annelies Fieuw
Candy Kumps
Alexander Schramm
Björn Menten
Johannes Schulte
Nadine Van Roy
Sarah Vergult
Rosa Noguera
Rogier Versteeg
R Stallings
et al.
C3
Conferentie
2011
Karyotyping, is it worthwhile in transsexualism?
Adrien Inoubli
GRETA DE CUYPERE
Robert Rubens
GUNTER HEYLENS
Els Elaut
Eva Van Caenegem
Björn Menten
Guy T'Sjoen
A1
Artikel in een tijdschrift
in
JOURNAL OF SEXUAL MEDICINE
2011
Klinische en genetische aspecten van het syndroom van Turner
BARBARA DELLE CHIAIE
Björn Menten
Anne De Paepe
Jean De Schepper
Sandra Janssens
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2011
Mitotic microhomology-mediated replication-based mechanisms underlie non-recurrent pathogenic microdeletions of the FOXL2 gene or its regulatory domain
Hannah Verdin
Barbara D'haene
Yana Novikova
DIANE BEYSEN
Pablo Lapunzina
Julian Nevado
Claudia Carvalho
James Lupski
Björn Menten
Elfride De Baere
C3
Conferentie
2011
Nasal speech and hypothyroidism are common hallmarks of 12q15 microdeletions
Sarah Vergult
Danijela Krgovic
Bart Loeys
Stanislas Lyonnet
Agne Liedén
Britt-Marie Anderlid
Freddie Sharkey
Shelagh Joss
Geert Mortier
Björn Menten
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2011
Nasal speech and hypothyroidism are common hallmarks of 12q15 microdeletions
Sarah Vergult
Danijela Krgovic
Bart Loeys
Stanislas Lyonnet
A Liedén
Britt-Marie Anderlid
Freddy Sharkey
Shelagh Joss
Geert Mortier
Björn Menten
C3
Conferentie
2011
Nasal speech and hypothyroidism are common hallmarks of 12q15 microdeletions
Sarah Vergult
Danijela Krgovic
Bart Loeys
Stanislas Lyonnet
A Liéden
Britt-Marie Anderlid
Freddy Sharkey
Shelagh Joss
Geert Mortier
Björn Menten
C3
Conferentie
2011
Nasal speech and hypothyroidism are common hallmarks of 12q15 microdeletions
Sarah Vergult
Danijela Krgovic
Bart Loeys
Stanislas Lyonnet
A Liedén
Britt-Marie Anderlid
Freddy Sharkey
Shelagh Joss
Geert Mortier
Björn Menten
C3
Conferentie
2011
Nonsyndromic bilateral and unilateral optic nerve aplasia: first familial occurrence and potential implication of CYP26A1 and CYP26C1 genes
Françoise Meire
Isabelle Delpierre
Cecile Brachet
Françoise Roulez
Chrisitan Van Nechel
Fanny Depasse
Catherine Christophe
Björn Menten
Elfride De Baere
A1
Artikel in een tijdschrift
in
MOLECULAR VISION
2011
The influence of early embryo traits on human embryonic stem cell derivation efficiency
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
Margot Van der Jeught
Björn Menten
Dieter Deforce
Maria Cornelissen
Susana Chuva de Sousa Lopes
Petra De Sutter
A1
Artikel in een tijdschrift
in
STEM CELLS AND DEVELOPMENT
2011
2010
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
Pieter Mestdagh
Erik Fredlund
Filip Pattyn
Ali Rihani
Tom Van Maerken
Joëlle Vermeulen
Candy Kumps
Björn Menten
Katleen De Preter
Alexander Schramm
et al.
C3
Conferentie
2010
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
Pieter Mestdagh
E Fredlund
Filip Pattyn
Ali Rihani
Tom Van Maerken
Joëlle Vermeulen
Candy Kumps
Björn Menten
Katleen De Preter
A Schramm
et al.
A1
Artikel in een tijdschrift
in
ONCOGENE
2010
Developmental delay and connective tissue disorder in four patients sharing a common microdeletion at 6q13-14
Hilde Van Esch
Elisabeth M Rosser
Sandra Janssens
Ingrid Van Ingelghem
Bart Loeys
Björn Menten
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2010
Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome
B Thienpont
F Bena
J Breckpot
N Philip
Björn Menten
H Van Esch
E Scalais
JM Salamone
CT Fong
JL Kussmann
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2010
Genotype-Phenotype Correlation in Eight New Patients With a Deletion Encompassing 2q31.1
D Mitter
BARBARA DELLE CHIAIE
HJ Ludecke
G Gillessen-Kaesbach
A Bohring
J Kohlhase
A Caliebe
R Siebert
A Ropke
MA Ramos-Arroyo
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2010
Giant axonal neuropathy caused by compound heterozygosity for a maternally inherited microdeletion and a paternal mutation within the GAN gene
Karen Buysse
Sarah Vergult
Silke Mussche
Chantal Ceuterick-De Groote
Franki Speleman
Björn Menten
Willy Lissens
Rudy Van Coster
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2010
Haploinsufficiency of TAB2 causes congenital heart defects in humans
Bernard Thienpont
Litu Zhang
Alex V Postma
Jeroen Breckpot
Leon-Charles Tranchevent
Peter Van Loo
Kjedl Mollgard
Niels Tommerup
Iben Bache
Zeynep Tumer
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF HUMAN GENETICS
2010
High-resolution breakpoint mapping of 38 regulatory and FOXL2 encompassing deletions in BPES using targeted microarrays
Hannah Verdin
Barbara D'haene
Pablo Lapunzina
Julian Nevado
Björn Menten
Elfride De Baere
C3
Conferentie
2010
Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines
An De Weer
Bruce Poppe
Sarah Vergult
Pieter Van Vlierberghe
Marjan Petrick
Robrecht De Bock
Yves Benoit
Lucien Noens
Anne De Paepe
Nadine Van Roy
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2010
Intragenic deletion of the AUTS2 gene in patients with mental retardation, autistic behaviour and dysmorphic features : a new microdeletion syndrome
Erik Sistermans
Els Voorhoeve
Gea Beunders
B van der Zwaag
HY Kroes
Sarah Vergult
Geert Mortier
Björn Menten
S Gana
JJ Saris
et al.
C3
Conferentie
2010
Preconceptueel en prenataal genetisch advies
BARBARA DELLE CHIAIE
Björn Menten
Anne De Paepe
Sandra Janssens
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
Report of an apparently balanced translocation disrupting the AUTS2 gene in a patient with developmental delay
Sarah Vergult
Geert Mortier
Franki Speleman
Björn Menten
C3
Conferentie
2010
Report of an apparently balanced translocation disrupting the AUTS2 gene in a patient with developmental delay
Sarah Vergult
Geert Mortier
Franki Speleman
Björn Menten
C3
Conferentie
2010
Report of an apparently balanced translocation disrupting the AUTS2 gene in a patient with developmental delay
Sarah Vergult
Geert Mortier
Franki Speleman
Björn Menten
C3
Conferentie
2010
Temple-Baraitser syndrome: a rare and possibly unrecognized condition
Adeline Jacquinet
Marion Gérard
Michael T Gabbett
Léon Rausin
Jean-Paul Misson
Björn Menten
Geert Mortier
Lionel Van Maldergem
Alain Verloes
Françoois-Guillaume Debray
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2010
Toepassing van microarray-analyse in de genetische diagnostiek
Björn Menten
Karen Buysse
Geert Mortier
Anne De Paepe
Franki Speleman
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
2009
Aicardi syndrome in a male patient
S Anderson
Björn Menten
M von Kogelenberg
S Robertson
M Waginger
HJ Mentzel
U Brandl
G Skirl
P Willems
A1
Artikel in een tijdschrift
in
NEUROPEDIATRICS
2009
Array comparative genomic hybridization and flow cytometry analysis of spontaneous abortions and mors in utero samples
Björn Menten
Katrien Swerts
BARBARA DELLE CHIAIE
Sandra Janssens
Karen Buysse
Jan Philippé
Franki Speleman
A1
Artikel in een tijdschrift
in
BMC MEDICAL GENETICS
2009
Autosomal dominant syndrome of mental retardation, hypotelorism, and cleft palate resembling Schilbach-Rott syndrome
Vared Shkalim
Hagit N Baris
Gavriel Gal
Ruth Gleiss
Shlomo Calderon
Marja Wessels
Anneke Maat-Kievit
Björn Menten
Elfride De Baere
Raoul CM Hennekam
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2009
Challenges for CNV interpretation in clinical molecular karyotyping: lessons learned from a 1001 sample experience
Karen Buysse
BARBARA DELLE CHIAIE
Rudy Van Coster
Bart Loeys
Anne De Paepe
Geert Mortier
Franki Speleman
Björn Menten
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2009
Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for Mutation Screening
Barbara D'haene
C Attanasio
DIANE BEYSEN
J Dostie
E Lemire
P Bouchard
M Field
K Jones
B Lorenz
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
PLOS GENETICS
2009
Extending the phenotype of recurrent rearrangements of 16p11.2: deletions in mentally retarded patients without autism and in normal individuals
EK Bijlsma
ACJ Gijsbers
JHM Schuurs-Hoeijmakers
A van Haeringen
DEF van de Putte
BM Anderlid
J Lundin
P Lapunzina
LAP Jurado
BARBARA DELLE CHIAIE
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2009
Fourteen new cases contribute to the characterization of the 7q11.23 microduplication syndrome
Nathalie Van der Aa
Liesbeth Rooms
Geert Vandeweyer
Jenneke van den Ende
Edwin Reyniers
Marco Fichera
Corrado Romano
BARBARA DELLE CHIAIE
Geert Mortier
Björn Menten
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2009
Further delineation of the 15q13 microdeletion and duplication syndromes: a clinical spectrum varying from non-pathogenic to a severe outcome
BWM van Bon
HC Mefford
Björn Menten
DA Koolen
AJ Sharp
WM Nillesen
JW Innis
TJL de Ravel
CL Mercer
M Fichera
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2009
Mapping of 5q35 chromosomal rearrangements within a genomically unstable region (vol 45, pg 672, 2008)
Karen Buysse
A Crepel
Björn Menten
Filip Pattyn
F Antonacci
JA Veltman
LA Larsen
Z Tumer
A de Klein
I van de Laar
et al.
Correctie
2009
Myhre syndrome: in search of the causal gene
Sarah Vergult
Marleen Simon
BARBARA DELLE CHIAIE
Ali Rihani
Franki Speleman
Geert Mortier
Björn Menten
C3
Conferentie
2009
Myhre syndrome: in search of the causal gene
Sarah Vergult
Marleen Simon
BARBARA DELLE CHIAIE
Ali Rihani
Franki Speleman
Geert Mortier
Björn Menten
C3
Conferentie
2009
Smoothing waves in array CGH tumor profiles
Mark A van de Wiel
Rebecca Brosens
Paul HC Eilers
Candy Kumps
Gerrit A Meijer
Björn Menten
Erik Sistermans
Franki Speleman
Marieke E Timmerman
Bauke Ylstra
A1
Artikel in een tijdschrift
in
BIOINFORMATICS
2009
The 12q14 microdeletion syndrome: additional patients and further evidence that HMGA2 is an important genetic determinant for human height
Karen Buysse
William Reardon
Lakshmi Mehta
Teresa Costa
Carrie Fagerstrom
Daniel J Kingsbury
George Anadiotis
Barbara C McGillivray
Jan Hellemans
Nicole de Leeuw
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2009
Unusual 8p inverted duplication deletion with telomere capture from 8q
Karen Buysse
F Antonacci
Bert Callewaert
Bart Loeys
Ulrike Fränkel
Victoria Siu
Geert Mortier
Franki Speleman
Björn Menten
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2009
2008
Array CGH: een nieuwe revolutionaire techniek in de detectie van chromosomale defecten bij kinderen met mentale retardatie en aangeboren afwijkingen
Björn Menten
Karen Buysse
Geert Mortier
Franki Speleman
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE
2008
Copy number alterations and copy number variation in cancer: close encounters of the bad kind
Franki Speleman
Candy Kumps
Karen Buysse
Bruce Poppe
Björn Menten
Katleen De Preter
A1
Artikel in een tijdschrift
in
CYTOGENETIC AND GENOME RESEARCH
2008
Delineation of a critical region on chromosome 18 for the del(18)(q12.2q21.1) syndrome
Karen Buysse
Björn Menten
Ann Oostra
Sylvie Tavernier
Geert Mortier
Franki Speleman
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2008
Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics
Jo Vandesompele
Evi Michels
Katleen De Preter
Björn Menten
Alexander Schramm
Angelika Eggert
Peter F Ambros
Valérie Combaret
Nadine Francotte
Francesca Antonacci
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF CANCER
2008
Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma
Katleen De Preter
Björn Menten
Sara De Brouwer
Candy Kumps
Evi Michels
Nadine Van Roy
Jo Vandesompele
Franki Speleman
A1
Artikel in een tijdschrift
in
CANCER LETTERS
2008
Mapping of 5q35 chromosomal rearrangements within a genomically unstable region
Karen Buysse
A CREPEL
Björn Menten
Filip Pattyn
F ANTONACCI
J VELTMAN
L LARSEN
Z TüMER
A DE KLEIN
I VAN DE LAAR
et al.
A1
Artikel in een tijdschrift
in
Journal of Medical Genetics
2008
Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes
HC MEFFORD
AJ SHARP
C BAKER
A ITSARA
ZS JIANG
Karen Buysse
SW HUANG
VK MALONEY
JA CROLLA
D BARALLE
et al.
A1
Artikel in een tijdschrift
in
NEW ENGLAND JOURNAL OF MEDICINE
2008
2007
Array CGH analysis of subnanogram quantities of DNA using whole genome amplification: opportunities for detection of copy number alterations in Hodgkin's lymphoma
Tom Feys
Bart Poppe
Bruno Verhasselt
Pascale De Paepe
Björn Menten
Jo Vandesompele
Nadine Van Roy
Anne De Paepe
Franki Speleman
C3
Conferentie
2007
ArrayCGH based classification of neuroblastoma into genomic subgroups
Sara De Brouwer
Evi Michels
Jo Vandesompele
Katleen De Preter
Jasmien Hoebeeck
Joëlle Vermeulen
Alexander Schramm
Jan J Molenaar
Björn Menten
Barbara Marques
et al.
C3
Conferentie
2007
ArrayCGH-based classification of neuroblastoma into genomic subgroups
Evi Michels
Jo Vandesompele
Katleen De Preter
Jasmien Hoebeeck
Joëlle Vermeulen
Alexander Schramm
Jan J Molenaar
Björn Menten
Barbara Marques
Raymond L Stallings
et al.
A1
Artikel in een tijdschrift
in
GENES CHROMOSOMES & CANCER
2007
High resolution DNA copy number analysis of constitutional chromosomal aberrations in human genomic disorders
Björn Menten
F Speleman
Proefschrift
2007
High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors
Jasmien Hoebeeck
Evi Michels
Björn Menten
Nadine Van Roy
Angelika Eggert
Alexander Schramm
Katleen De Preter
Nurten Yigit
Els De Smet
Anne De Paepe
et al.
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF CANCER
2007
Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations
S VAN VOOREN
B THIENPONT
Björn Menten
Franki Speleman
B DE MOOR
J VERMEESCH
Y MOREAU
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2007
Osteopoikilosis, short stature and mental retardation as key features of a new microdeletion syndrome on 12q14
Björn Menten
Karen Buysse
F ZAHIR
Jan Hellemans
SJ HAMILTON
T COSTA
C FAGERSTROM
G ANADIOTIS
D KINGSBURY
BC MCGILLIVRAY
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2007
RANBP17-TLX3: A hot spot region for both constitutional and acquired rearrangements
Karen Buysse
Björn Menten
F ANTONACCI
JA VELTMAN
LA LARSEN
Z TUMER
Geert Mortier
Franki Speleman
C3
Conferentie
2007
Report of a female patient with mental retardation and tall stature due to a chromosomal rearrangement disrupting the OPHN1 gene on Xq12
Björn Menten
Karen Buysse
Stefan Vermeulen
VALERIE MEERSSCHAUT
Jo Vandesompele
BL NG
NP CARTER
Geert Mortier
Franki Speleman
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2007
Subtelomeric imbalances in phenotypically normal individuals
I BALIKOVA
Björn Menten
T DE RAVEL
C LE CAIGNEC
B THIENPONT
M URBINA
M DOCO-FENZY
M DE RADEMAEKER
Geert Mortier
F KOOY
et al.
A1
Artikel in een tijdschrift
in
HUMAN MUTATION
2007
2006
Array CGH: een nieuwe revolutionaire techniek in de detectie van chromosomale defecten
Björn Menten
Karen Buysse
Geert Mortier
Franki Speleman
A4
Artikel in een tijdschrift
in
DE AGENDA PEDIATRIE (BRUSSEL)
2006
Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports
Björn Menten
N MAAS
B THIENPONT
Karen Buysse
Jo Vandesompele
C MELOTTE
T DE RAVEL
S VAN VOOREN
I BALIKOVA
L BACKX
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL GENETICS
2006
Genome wide measurement of DNA copy number changes in neuroblastoma: dissecting amplicons and mapping losses, gains and breakpoints
Evi Michels
Jo Vandesompele
Jasmien Hoebeeck
Björn Menten
Katleen De Preter
Genevieve Laureys
Nadine Van Roy
Franki Speleman
A1
Artikel in een tijdschrift
in
CYTOGENETIC AND GENOME RESEARCH
2006
Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1
Nadine Van Roy
Jo Vandesompele
Björn Menten
H NILSSON
Els De Smet
M ROCCHI
Anne De Paepe
S PAHLMAN
Franki Speleman
A1
Artikel in een tijdschrift
in
GENES CHROMOSOMES & CANCER
2006
2005
Familial pericentric inversion of chromosome 18: behavioral abnormalities in patients heterozygous for either the dup(18p)/del(18q) or dup(18q)/del(18p) recombinant chromosome
Stefan Vermeulen
Franki Speleman
L VANRANSBEECK
Jasmine Verspeet
Björn Menten
MR VERSCHRAEGEN-SPAE
Philippe De Wilde
Ludwine Messiaen
RC MICHAELIS
Juliaan Leroy
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF HUMAN GENETICS
2005
Identification of an unbalanced X-autosome translocation by array CGH in a boy with a syndromic form of chondrodysplasia punctata brachytelephalangic type
Björn Menten
Karen Buysse
Jo Vandesompele
Els De Smet
Anne De Paepe
Franki Speleman
Geert Mortier
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF MEDICAL GENETICS
2005
Molecular karyotyping: Array CGH quality criteria for constitutional genetic diagnosis
JR VERMEESCH
C MELOTTE
G FROYEN
S VAN VOOREN
B DUTTA
N MAAS
S VERMEULEN
Björn Menten
Franki Speleman
B DE MOOR
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
2005
Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11
Katleen De Preter
Jo Vandesompele
Björn Menten
Philippa Carr
Heike Fiegler
Anders Edsjö
Nigel P Carter
Nurten Yigit
Wim Waelput
Nadine Van Roy
et al.
A1
Artikel in een tijdschrift
in
BMC GENOMICS
2005
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
Björn Menten
Filip Pattyn
Katleen De Preter
Piet Robbrecht
Evi Michels
Karen Buysse
Geert Mortier
Anne De Paepe
Steven van Vooren
Joris Vermeesch
et al.
A1
Artikel in een tijdschrift
in
BMC BIOINFORMATICS
2005
2004
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons
Katleen De Preter
Filip Pattyn
Geert Berx
Kristin Strumane
Björn Menten
Frans Van Roy
Anne De Paepe
Franki Speleman
Jo Vandesompele
A1
Artikel in een tijdschrift
in
BMC GENOMICS
2004
DUP25 remains unconfirmed
Stefan Vermeulen
Björn Menten
Sylvia De Bie
Paul Coucke
Fransiska Malfait
Julie De Backer
Franki Speleman
Anne De Paepe
B LOEYS
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2004
Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis
Jan Hellemans
O PREOBRAZHENSKA
Andy Willaert
P DEBEER
PETER VERDONK
T COSTA
K JANSSENS
Björn Menten
Nadine Van Roy
Stefan Vermeulen
et al.
A1
Artikel in een tijdschrift
in
NATURE GENETICS
2004
Molecular cytogenetic analysis of complex chromosomal rearrangements in patients with mental retardation and congenital malformations: delineation of 7q21.11 breakpoints
Stefan Vermeulen
Björn Menten
Nadine Van Roy
Heidi Van Limbergen
Anne De Paepe
Geert Mortier
Franki Speleman
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2004