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Researcher
Bart De Spiegeleer
Profile
Projects
Publications
Activities
396
Results
2021
Adjunctive use of statins for COVID-19
Mike Sathekge
Geert Byttebier
Bart De Spiegeleer
Bo Saxberg
Veronica Ueckermann
Luc Belmans
Myriam Alexander
David Fedson
Editorial material
2021
Apoptosis imaging in oncology by means of positron emission tomography : a review
Christophe Van De Wiele
Sezgin Ustmert
Bart De Spiegeleer
Pieter-Jan De Jonghe
Mike Sathekge
Maes Alex
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Applications in medicine : mental health
Yorick Janssens
Evelien Wynendaele
Kurt Audenaert
Bart De Spiegeleer
Bookchapter
in
Biologically active peptides : from basic science to applications for human health
2021
BBPpred : sequence-based prediction of blood-brain barrier peptides with feature representation learning and logistic regression
Ruyu Dai
Wei Zhang
Wending Tang
Evelien Wynendaele
Qizhi Zhu
Yannan Bin
Bart De Spiegeleer
Junfeng Xia
A1
Journal Article
in
JOURNAL OF CHEMICAL INFORMATION AND MODELING
2021
Conformational stability as a quality attribute for the cell therapy raw material human serum albumin
Evelien Wynendaele
Gamaliel Junren Ma
Xiaolong Xu
Nam-Joon Cho
Bart De Spiegeleer
A1
Journal Article
in
RSC ADVANCES
2021
Cov-MS : a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients
Bart Van Puyvelde
Katleen Van Uytfanghe
Olivier Tytgat
Laurence Van Oudenhove
Ralf Gabriels
Robbin Bouwmeester
Simon Daled
Tim Van Den Bossche
Pathmanaban Ramasamy
Sigrid Verhelst
Laura De Clerck
Laura Corveleyn
Sander Willems
Nathan Debunne
Evelien Wynendaele
Bart De Spiegeleer
Péter Judák
Kris Roels
Laurie De Wilde
Peter Van Eenoo
Tim Reyns
Marc Cherlet
Emmie Dumont
Griet Debyser
Ruben t’Kindt
Koen Sandra
Surya Gupta
Nicolas Drouin
Amy Harms
Thomas Hankemeier
Donald J. L. Jones
Pankaj Gupta
Dan Lane
Catherine S. Lane
Said El Ouadi
Jean-Baptiste Vincendet
Nick Morrice
Stuart Oehrle
Nikunj Tanna
Steve Silvester
Sally Hannam
Florian C. Sigloch
Andrea Bhangu-Uhlmann
Jan Claereboudt
N. Leigh Anderson
Morteza Razavi
Sven Degroeve
Lize Cuypers
Christophe Stove
Katrien Lagrou
Geert A. Martens
Dieter Deforce
Lennart Martens
Johannes P. C. Vissers
Maarten Dhaenens
A2
Journal Article
in
JACS AU
2021
Dietary muramidase degrades bacterial peptidoglycan to NOD-activating muramyl dipeptides and reduces duodenal inflammation in broiler chickens
Ya Wang
Evy Goossens
Venessa Eeckhaut
Estefania Pérez Calvo
Rual Lopez-Ulibarri
Irene Eising
Mikkel Klausen
Nathan Debunne
Bart De Spiegeleer
Richard Ducatelle
Filip Van Immerseel
A1
Journal Article
in
BRITISH JOURNAL OF NUTRITION
2021
Environmental risk assessment of the anthelmintic albendazole in Eastern Africa, based on a systematic review
Sileshi Belew
Sultan Suleman
Evelien Wynendaele
Luc Duchateau
Bart De Spiegeleer
A1
Journal Article
in
ENVIRONMENTAL POLLUTION
2021
Faecal microbiota transplants : why do we not consider them as Advanced Therapy Medicinal Products?
Frederick Verbeke
Bart De Spiegeleer
A1
Journal Article
in
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
2021
Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBs
Geert Byttebier
Luc Belmans
Myriam Alexander
Bo E. H. Saxberg
Bart De Spiegeleer
Anton De Spiegeleer
Nick Devreker
Jens Van Praet
Karolien Vanhove
Reinhilde Reybrouck
Evelien Wynendaele
David S. Fedson
A1
Journal Article
in
HUMAN VACCINES & IMMUNOTHERAPEUTICS
2021
PapRIV : a BV-2 microglial cell activating quorum sensing peptide
Yorick Janssens
Nathan Debunne
Anton De Spiegeleer
Evelien Wynendaele
Marta Planas
Lidia Feliu
Alessandra Quarta
Christel Claes
Debby Van Dam
Peter Paul De Deyn
Peter Ponsaerts
Matthew Blurton-Jones
Bart De Spiegeleer
A1
Journal Article
in
SCIENTIFIC REPORTS
2021
Quorum sensing peptides as a novel microbiomal causative factor in promoting colorectal cancer metastasis : the EntF metabolite case
Nathan Debunne
Bart De Spiegeleer
Evelien Wynendaele
Dissertation
2021
Statin intake and all-cause mortality among older nursing home residents
Anton De Spiegeleer
Jordi Van Migerode
Antoon Bronselaer
Evelien Wynendaele
Milan Peelman
Filip Vandaele
Geert Byttebier
Guy De Tré
Luc Belmans
Christophe Van De Wiele
Mike Sathekge
Diemer Van Dijck
Bo Saxberg
Myriam Alexander
David Fedson
Dirk Elewaut
Nele Van Den Noortgate
Bart De Spiegeleer
A1
Journal Article
in
GERONTOLOGY
2021
2020
A simplified checklist for the visual inspection of finished pharmaceutical products : a way to empower frontline health workers in the fight against poor-quality medicines
B. Schiavetti
Evelien Wynendaele
V Melotte
J. Van der Elst
Bart De Spiegeleer
R. Ravinetto
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE
2020
Blood-brain barrier transport kinetics of NOTA-modified proteins : the somatropin case
Nathalie Bracke
Yorick Janssens
Evelien Wynendaele
Liesa Tack
Alex Maes
Christophe Van De Wiele
Mike Sathekge
Bart De Spiegeleer
A1
Journal Article
in
QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2020
Cov-MS : a community-based template assay for clinical MS-based protein detection in SARS-CoV-2 patients
Bart Van Puyvelde
Katleen Van Uytfanghe
Olivier Tytgat
L. Van Oudenhove
Ralf Gabriels
Robbin Bouwmeester
Simon Daled
Tim Van Den Bossche
Pathmanaban Ramasamy
Sigrid Verhelst
Laura De Clerck
Laura Corveleyn
Nathan Debunne
Evelien Wynendaele
Bart De Spiegeleer
Péter Judák
Kris Roels
Laurie De Wilde
Peter Van Eenoo
Tim Reyns
Marc Cherlet
E. Dumont
G. Debyser
R. t’Kindt
K. Sandra
Surya Gupta
Nicolas Drouin
Amy Harms
Thomas Hankemeier
DJL Jones
P. Gupta
D. Lane
C.S. Lane
S. El Ouadi
JB. Vincendet
N. Morrice
S. Oehrle
N. Tanna
S. Silvester
S. Hannam
F. Sigloch
A. Bhangu-Uhlmann
J. Claereboudt
L. Anderson
M. Razavi
Sven Degroeve
L. Cuypers
Christophe Stove
K. Lagrou
G. Martens
Dieter Deforce
Lennart Martens
J.P.C. Vissers
Maarten Dhaenens
Preprint
2020
Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets
Sileshi Belew Yohannes
Sultan Suleman
Markos Duguma
Henok Teshome
Evelien Wynendaele
Luc Duchateau
Bart De Spiegeleer
A1
Journal Article
in
MALARIA JOURNAL
2020
Functional quality of selected antimalarial and antihelminthic medicines
Sileshi Belew Yohannes
Bart De Spiegeleer
Luc Duchateau
Sultan Suleman
Dissertation
2020
Influence of blood collection methods and long-term plasma storage on quorum-sensing peptide stability
Nathan Debunne
Anton De Spiegeleer
Dorian Depuydt
Yorick Janssens
Amélie Descamps
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
ACS OMEGA
2020
LC-MS compatible antiadsorption diluent for peptide analysis
Frederick Verbeke
Nathalie Bracke
Nathan Debunne
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2020
MEK1/2 inhibition in murine heart and aorta after oral administration of refametinib supplemented drinking water
Felke Steijns
Nathalie Bracke
Marjolijn Renard
Julie De Backer
Patrick Sips
Nathan Debunne
Evelien Wynendaele
Frederick Verbeke
Bart De Spiegeleer
Laurence Campens
A1
Journal Article
in
FRONTIERS IN PHARMACOLOGY
2020
Quality characterization of raw materials used in advanced therapy medicinal products : HEPES, APMg and albumin
Xiaolong Xu
Bart De Spiegeleer
Dissertation
2020
Quorum Sensing Peptides and Their Interactions with the Host
Evelien Wynendaele
Nathan Debunne
Frederick Verbeke
Yorick Janssens
Anton De Spiegeleer
Bart De Spiegeleer
Bookchapter
in
ACS Symposium Series
2020
Quorum sensing molecules as a novel microbial factor impacting muscle cells
Anton De Spiegeleer
Dirk Elewaut
Nele Van Den Noortgate
Yorick Janssens
Nathan Debunne
Selien Van Langenhove
Srinath Govindarajan
Bart De Spiegeleer
Evelien Wynendaele
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
2020
Quorum sensing peptides as possible brain-influencing microbiome mediators
Yorick Janssens
Bart De Spiegeleer
Evelien Wynendaele
Dissertation
2020
Structural study of L-ascorbic acid 2-phosphate magnesium, a raw material in cell and tissue therapy
Xiaolong Xu
Magdalena Wozniczka
Kristof Van Hecke
Dieter Buyst
Dimitrije Mara
Chris Vervaet
Karen Herman
Evelien Wynendaele
Eric Deconinck
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
2020
The effects of ARBs, ACEis, and statins on clinical outcomes of COVID-19 infection among nursing home residents
Anton De Spiegeleer
Antoon Bronselaer
James T. Teo
Geert Byttebier
Guy De Tré
Luc Belmans
Richard Dobson
Evelien Wynendaele
Christophe Van de Wiele
Filip Vandaele
Diemer Van Dijck
Dan Bean
David Fedson
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
2020
Thermal sensitivity as a quality control attribute for biotherapeutics : the L‐asparaginase case
Han Yao
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
DRUG TESTING AND ANALYSIS
2020
2019
A Surface Acoustic Wave (SAW) biosensor method for functional quantification of E. coli l-asparaginase
Han Yao
Cristina Soto Fernández
Xiaolong Xu
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
TALANTA
2019
Bacterial quorum sensing peptides as mediators of the gut-brain axis
Yorick Janssens
Evelien Wynendaele
Nathan Debunne
Kurt Audenaert
Debby Van Dam
Alessandra Quarta
Peter Ponsaerts
Bart De Spiegeleer
C3
Conference
2019
Biological characterisation of somatropin-derived cryptic peptides
Liesa Tack
Nathalie Bracke
Frederick Verbeke
Evelien Wynendaele
Ewald Pauwels
Alex Maes
Christophe Van de Wiele
Mike Sathekge
Bart De Spiegeleer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
2019
Disbiome : a database describing microbiome alterations in different disease states
Yorick Janssens
Antoon Bronselaer
Evelien Wynendaele
Guy De Tré
Bart De Spiegeleer
Bookchapter
in
Reference module in biomedical sciences
2019
Distinct neutrophil C5a receptor inflammatory events in cows initiated by chemoattractant C5a and lipopolysaccharide around parturition and in mid lactation
Xanthippe Boulougouris
Carolien Rogiers
Mario Van Poucke
Bart De Spiegeleer
Luc Peelman
Luc Duchateau
Christian Burvenich
A1
Journal Article
in
JOURNAL OF DAIRY SCIENCE
2019
Hazard analysis of falsified peptide 'medicines'
Steven Janvier
Bart De Spiegeleer
Eric Deconinck
Celine Vanhee
Dissertation
2019
Hot-melt preparation of a non-biodegradable peptide implant : a proof of principle
Matthias D'Hondt
Frederick Verbeke
Pieter Wuytens
Andre Skirtach
Bart De Spiegeleer
Evelien Wynendaele
A1
Journal Article
in
PROTEIN AND PEPTIDE LETTERS
2019
Methylation of selected CpG islands involved in the transcription of myeloperoxidase and superoxide dismutase 2 in neutrophils of periparturient and mid-lactation cows
Xanthippe Boulougouris
Carolien Rogiers
Mario Van Poucke
Bart De Spiegeleer
Luc Peelman
Luc Duchateau
Christian Burvenich
A1
Journal Article
in
JOURNAL OF DAIRY SCIENCE
2019
PSMA-targeting positron emission agents for imaging solid tumors other than non-prostate carcinoma : a systematic review
Christophe Van De Wiele
Mike Sathekge
Bart De Spiegeleer
Pieter-Jan De Jonghe
Laurence Beels
Alex Maes
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Peptides as epigenetic modulators : therapeutic implications
Yorick Janssens
Evelien Wynendaele
Wim Vanden Berghe
Bart De Spiegeleer
A1
Journal Article
in
CLINICAL EPIGENETICS
2019
Pharmaceutical compounding of orphan active ingredients in Belgium : how community and hospital pharmacists can address the needs of patients with rare diseases
Valérie Vanhoorne
E Peeters
Inge Van Tongelen
Koen Boussery
Evelien Wynendaele
Bart De Spiegeleer
Jean Paul Remon
Chris Vervaet
A1
Journal Article
in
ORPHANET JOURNAL OF RARE DISEASES
2019
Quality exploration of L-asparaginase : analytical characterization
Han Yao
Bart De Spiegeleer
Dissertation
2019
Quality of fixed dose artemether/lumefantrine products in Jimma Zone, Ethiopia
Sileshi Belew Yohannes
Sultan Suleman
Tesfaye Mohammed
Yimer Mekonnen
Markos Duguma
Henok Teshome
Bikila Bayisa
Evelien Wynendaele
Mathias D'Hondt
Luc Duchateau
Bart De Spiegeleer
A1
Journal Article
in
MALARIA JOURNAL
2019
Residual active pharmaceutical ingredient on the primary packaging of medicines : a valuable GMP-marker
Evelien Wynendaele
Miguel Colpaert
Nathan Debunne
Anne Kosgei
Bart De Spiegeleer
A1
Journal Article
in
TALANTA
2019
Zwitterionic-hydrophilic interaction liquid chromatography for L-ascorbic acid 2-phosphate magnesium, a raw material in cell therapy
Xiaolong Xu
Jonas Urlaub
Magdalena Woźniczka
Evelien Wynendaele
Karen Herman
Curd Schollmayer
Bernd Diehl
Serge Van Calenbergh
Ulrike Holzgrabe
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2019
2018
99mTc-HMPAO SPECT after single and repeated subanaesthetic ketamine in healthy dogs
Lise Vlerick
Kathelijne Peremans
Robrecht Dockx
Kurt Audenaert
Chris Baeken
Bart De Spiegeleer
Jimmy Saunders
Tim Bosmans
Ingeborgh Polis
C3
Conference
2018
Analysis of iodinated quorum sensing peptides by LC-UV/ESI ion trap mass spectrometry
Yorick Janssens
Frederick Verbeke
Nathan Debunne
Evelien Wynendaele
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2018
Are injectable illegal polypeptide drugs safe? : case report demonstrating the presence of haemolytic Bacillus cereus in two illegal peptide drugs
Steven Janvier
Elke Wattijn
Nadine Botteldoorn
Bart De Spiegeleer
Eric Deconinck
Celine Vanhee
A1
Journal Article
in
DRUG TESTING AND ANALYSIS
2018
Characterisation of magnesium ascorbyl phosphate, a raw material in cell therapy
Xiaolong Xu
Magdalena Woźniczka
Toon Verstraelen
Kristof Van Hecke
Patrick Bultinck
Carl Mensch
Dieter Buyst
Eric Deconinck
Evelien Wynendaele
Karen Herman
Bart De Spiegeleer
C3
Conference
2018
Chromatography of quorum sensing peptides : an important functional class of the bacterial peptidome
Nathan Debunne
Frederick Verbeke
Yorick Janssens
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
CHROMATOGRAPHIA
2018
Circular dichroism in functional quality evaluation of medicines
Han Yao
Evelien Wynendaele
Xiaolong Xu
Anne Kosgei
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2018
Detection and quantification of Enterococcus faecalis RNPP-type quorum sensing peptides in bacterial culture media by UHPLC-MS
Frederick Verbeke
Nathan Debunne
Yorick Janssens
Liesa Tack
Evelien Wynendaele
Petra Rigole
Tom Coenye
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2018
Development of a capillary zone electrophoresis method to quantify E. coli L-asparaginase and its acidic variants
Han Yao
Jana Vandenbossche
Cari E Sänger-van de Griend
Yorick Janssens
Cristina Soto Fernández
Xiaolong Xu
Evelien Wynendaele
Govert Willem Somsen
Rob Haselberg
Bart De Spiegeleer
A1
Journal Article
in
TALANTA
2018
Disbiome database : linking the microbiome to disease
Yorick Janssens
Joachim Nielandt
Antoon Bronselaer
Nathan Debunne
Frederick Verbeke
Evelien Wynendaele
Filip Van Immerseel
Yves-Paul Vandewynckel
Guy De Tré
Bart De Spiegeleer
A1
Journal Article
in
BMC MICROBIOLOGY
2018
Do quorum sensing peptides play a role in psychiatric disorders?
Evelien Wynendaele
Yorick Janssens
Nathan Debunne
Kurt Audenaert
Bart De Spiegeleer
C3
Conference
2018
Falsification of biotechnology drugs : current dangers and/or future disasters?
Steven Janvier
Bart De Spiegeleer
Celine Vanhee
Eric Deconinck
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2018
Impurity profiling of the most frequently encountered falsified polypeptide drugs on the Belgian market
Steven Janvier
Karlien Cheyns
Michaël Canfyn
Séverine Goscinny
Bart De Spiegeleer
Celine Vanhee
Eric Deconinck
A1
Journal Article
in
TALANTA
2018
Is there a role for quorum sensing peptides in cancer?
Evelien Wynendaele
Yorick Janssens
Nathan Debunne
Olivier De Wever
Bart De Spiegeleer
C3
Conference
2018
Quality of anthelminthic medicines available in Jimma Ethiopia
Sileshi Belew Yohannes
Sultan Suleman
Evelien Wynendaele
Matthias D'Hondt
Anne Kosgei
Luc Duchateau
Bart De Spiegeleer
A1
Journal Article
in
ACTA TROPICA
2018
Quality of isotopically labelled internal standards for peptide quantification
Nathan Debunne
Frederick Verbeke
Yorick Janssens
Liesa Tack
Evelien Wynendaele
Bart De Spiegeleer
C3
Conference
2018
Regulatory status of N-alkylamide containing health products
Evelien Wynendaele
Bart De Spiegeleer
Bert Gevaert
Yorick Janssens
Sultan Suleman
Steven Cattoor
Jimmy Saunders
Lieselotte Veryser
A1
Journal Article
in
REGULATORY TOXICOLOGY AND PHARMACOLOGY
2018
Residual API on the packaging : a GMP-marker?
Evelien Wynendaele
Miguel Colpaert
Anne Kosgei
Nathan Debunne
Bart De Spiegeleer
C3
Conference
2018
Screening of quorum sensing peptides for biological effects in neuronal cells
Yorick Janssens
Evelien Wynendaele
Frederick Verbeke
Nathan Debunne
Bert Gevaert
Kurt Audenaert
Christophe Van De Wiele
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2018
The influence of subanaesthetic ketamine on regional cerebral blood flow in healthy dogs measured with 99mTc-HMPAO SPECT
Lise Vlerick
Kathelijne Peremans
Robrecht Dockx
Kurt Audenaert
Chris Baeken
Bart De Spiegeleer
Jimmy Saunders
Ingeborgh Polis
A1
Journal Article
in
PLOS ONE
2018
The quality of medicines used in children and supplied by private pharmaceutical wholesalers in Kinshasa, Democratic Republic of Congo : a prospective survey
Benedetta Schiavetti
Evelien Wynendaele
Bart De Spiegeleer
Geremie J Mbinze
Nicodème Kalenda
Roland Marini
Vera Melotte
Epco Hasker
Bruno Meessen
Raffaella Ravinetto
Josiane Van der Elst
Daniel Mutolo Ngeleka
A1
Journal Article
in
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
2018
Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide
Joshua A Jackman
Vivian V Costa
Soohyun Park
Ana Luiza CV Real
Jae Hyeon Park
Pablo L Cardozo
Abdul Rahim Ferhan
Isabella G Olmo
Thaiane P Moreira
Jordana L Bambirra
Victoria F Queiroz
Celso M Queiroz-Junior
Giselle Foureaux
Danielle G Souza
Fabiola M Ribeiro
Bo Kyeong Yoon
Evelien Wynendaele
Bart De Spiegeleer
Mauro M Teixeira
Nam-Joon Cho
A1
Journal Article
in
NATURE MATERIALS
2018
Treatment of malaria and related symptoms using traditional herbal medicine in Ethiopia
Sultan Suleman
Takele Beyene Tufa
Dereje Kebebe
Sileshi Belew
Yimer Mekonnen
Fanta Gashe
Seid Mussa
Evelien Wynendaele
Luc Duchateau
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF ETHNOPHARMACOLOGY
2018
2017
Analysis of illegal peptide drugs via HILIC-DAD-MS
Steven Janvier
Evelien De Sutter
Evelien Wynendaele
Bart De Spiegeleer
Celine Vanhee
Eric Deconinck
A1
Journal Article
in
TALANTA
2017
Analytics in microbiome : investigating quorum sensing peptides
Nathan Debunne
Frederick Verbeke
Evelien Wynendaele
Yorick Janssens
Bart De Spiegeleer
C3
Conference
2017
Are injectable SFFC polypeptide drugs safe? : case report demonstrating the presence of haemolytic Bacillus cereus in two illegal polypeptide drugs
Steven Janvier
E Wattijn
N Botteldoorn
Bart De Spiegeleer
E Deconinck
C Vanhee
C3
Conference
2017
Chemical classification of cyclic depsipeptides
Lien Taevernier
Evelien Wynendaele
Bert Gevaert
Bart De Spiegeleer
A1
Journal Article
in
CURRENT PROTEIN AND PEPTIDE SCIENCE
2017
Exploration of cryptic peptides : analytical, pharmacological and regulatory contributions
Bert Gevaert
Bart De Spiegeleer
Dissertation
2017
Faecal microbiota transplantation : a regulatory hurdle?
Frederick Verbeke
Yorick Janssens
Evelien Wynendaele
Bart De Spiegeleer
Editorial material
2017
Hydrophilic interaction liquid chromatography method development and validation for the assay of HEPES zwitterionic buffer
Xiaolong Xu
Bert Gevaert
Nathalie Bracke
Han Yao
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2017
Identification and quantification of falsified peptide drugs via HILIC-DAD-MS
Steven Janvier
Evelien De Sutter
Evelien Wynendaele
Bart De Spiegeleer
Celine Vanhee
Eric Deconinck
C3
Conference
2017
In vitro functional quality characterization of NOTA-modified somatropins
Nathalie Bracke
Han Yao
Evelien Wynendaele
Frederick Verbeke
Xiaolong Xu
Bert Gevaert
Alex Maes
Christophe Van De Wiele
Mike Sathekge
Sarah De Saeger
Bart De Spiegeleer
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2017
N-alkylamide profiling of Achillea ptarmica and Achillea millefolium extracts by liquid and gas chromatography-mass spectrometry
Lieselotte Veryser
Lien Taevernier
Evelien Wynendaele
Yannick Verheust
Ann Dumoulin
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2017
Peptides as quorum sensing molecules : measurement techniques and obtained levels in vitro and in vivo
Frederick Verbeke
Severine De Craemer
Nathan Debunne
Yorick Janssens
Evelien Wynendaele
Christophe Van de Wiele
Bart De Spiegeleer
A1
Journal Article
in
FRONTIERS IN NEUROSCIENCE
2017
Poor dissolution of anthelminthic medicines : a risk for reduced efficacy
B Sileshi
S Sultan
Evelien Wynendaele
Kaat Anné
Luc Duchateau
Bart De Spiegeleer
Bruno Levecke
C3
Conference
2017
2016
An analytical quality by design (aQbD) approach for a L-asparaginaseactivity method
Han Yao
Jochem Vancoillie
Matthias D'Hondt
Evelien Wynendaele
Nathalie Bracke
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2016
An elastic liposomal formulation for RNAi-based topical treatment of skin disorders: proof-of-concept in the treatment of psoriasis
Eline Desmet
STEFANIE BRACKE
Katrien Forier
Lien Taevernier
Marc Stuart
Bart De Spiegeleer
Koen Raemdonck
Mireille Van Gele
Jo Lambert
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2016
Analytical, pharmacokinetic and regulatory characterisation of selected plant N-alkylamides
Lieselotte Veryser
Bart De Spiegeleer
Dissertation
2016
Bacterial quorum sensing peptides and the inter-kingdom communication with human cancer cells
Frederick Verbeke
Evelien Wynendaele
Yorick Janssens
Bart De Spiegeleer
C3
Conference
2016
Blood-brain barrier transport kinetics of the cyclic depsipeptide mycotoxins beauvericin and enniatins
Lien Taevernier
Nathalie Bracke
Lieselotte Veryser
Evelien Wynendaele
Bert Gevaert
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
TOXICOLOGY LETTERS
2016
Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT
Bert Gevaert
Evelien Wynendaele
Sofie Stalmans
Nathalie Bracke
Matthias D'Hondt
Ilse Smolders
Ann Van Eeckhaut
Bart De Spiegeleer
A1
Journal Article
in
NEUROPHARMACOLOGY
2016
Characterization data on the topical carrier DDC642
Eline Desmet
STEFANIE BRACKE
Katrien Forier
Lien Taevernier
Marc CA Stuart
Bart De Spiegeleer
Koen Raemdonck
Mireille Van Gele
Jo Lambert
A2
Journal Article
in
DATA IN BRIEF
2016
Do cyclic depsipeptide mycotoxins beauvericin and enniatins cross the blood-brain barrier?
Lien Taevernier
Nathalie Bracke
Lieselotte Veryser
Evelien Wynendaele
Bart De Spiegeleer
C3
Conference
2016
Exploration of the medicinal peptide space
Bert Gevaert
Sofie Stalmans
Evelien Wynendaele
Lien Taevernier
Nathalie Bracke
Matthias D'Hondt
Bart De Spiegeleer
A1
Journal Article
in
PROTEIN AND PEPTIDE LETTERS
2016
Fish hydrolysates : a regulatory perspective of bioactive peptides
Bert Gevaert
Lieselotte Veryser
Frederick Verbeke
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
PROTEIN AND PEPTIDE LETTERS
2016
Functional quality of somatropin derivatives : NOTA-modifications and peptides
Nathalie Bracke
Bart De Spiegeleer
Dissertation
2016
Human skin permeation of emerging mycotoxins (beauvericin and enniatins)
Lien Taevernier
Lieselotte Veryser
Nathalie Roche
Kathelijne Peremans
Christian Burvenich
Catherine Delesalle
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
2016
Hydrophilic interaction liquid chromatography method development and validation for the assay of HEPES zwitterionic buffer
Xiaolong Xu
Bert Gevaert
Nathalie Bracke
Han Yao
Evelien Wynendaele
Bart De Spiegeleer
C3
Conference
2016
Implementation of UHPLC-single quad MS platform : the next level transforming pharmaceutical quality control laboratories
Evelien Wynendaele
Bert Gevaert
Lieselotte Veryser
Xiaolong Xu
Frederick Verbeke
Bart De Spiegeleer
C3
Conference
2016
Implementation of a single quad MS detector in routine QC analysis of peptide drugs
Matthias D'Hondt
Bert Gevaert
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2016
Impurity profiling of L-asparaginase preparation
Han Yao
Nathalie Bracke
Bert Gevaert
Xiaolong Xu
Evelien Wynendaele
Rob Haselberg
Govert Somsen
Bart De Spiegeleer
C3
Conference
2016
Laser capture microdissection of intestinal tissue from sea bass larvae using an optimized RNA integrity assay and validated reference genes
Marlien Schaeck
Ward De Spiegelaere
Jurgen De Craene
Wim Van Den Broeck
Bart De Spiegeleer
Christian Burvenich
Freddy Haesebrouck
Annemie Decostere
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
Mucosal and blood-brain barrier transport kinetics of the plant N-alkylamide spilanthol using in vitro and in vivo models
Lieselotte Veryser
Lien Taevernier
Tanmayee Joshi
Pratima Tatke
Evelien Wynendaele
Nathalie Bracke
Sofie Stalmans
Kathelijne Peremans
Christian Burvenich
Martijn Risseeuw
Bart De Spiegeleer
A1
Journal Article
in
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
2016
Pharmaceutical regulatory framework in Ethiopia : a critical evaluation of its legal basis and implementation
Sultan Suleman Wega
Abdulkadir Woliyi
Kifle Woldemichael
Kora Tushune
Luc Duchateau
Agnes Degroote
Roy Vancauwenberghe
Nathalie Bracke
Bart De Spiegeleer
A2
Journal Article
in
ETHIOPIAN JOURNAL OF HEALTH SCIENCES
2016
Pre-clinical pharmacokinetics of selected quorum sensing peptides
Yorick Janssens
Evelien Wynendaele
Frederick Verbeke
Bart De Spiegeleer
C3
Conference
2016
Quality control of cationic cell-penetrating peptides
Sofie Stalmans
Bert Gevaert
Frederick Verbeke
Matthias D'Hondt
Nathalie Bracke
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2016
Quality of selected medicines in Ethiopia: analytical and regulatory contributions
Sultan Suleman Wega
Bart De Spiegeleer
Dissertation
2016
Quantitative in vitro and in vivo evaluation of intestinal and blood-brain barrier transport kinetics of the plant N-alkylamide pellitorine
Lieselotte Veryser
Nathalie Bracke
Evelien Wynendaele
Tanmayee Joshi
Pratima Tatke
Lien Taevernier
Bart De Spiegeleer
A1
Journal Article
in
BIOMED RESEARCH INTERNATIONAL
2016
Quorum sensing peptides: the missing link between microbiome and disease?
Evelien Wynendaele
Frederick Verbeke
Yorick Janssens
Nathan Debunne
Bart De Spiegeleer
C3
Conference
2016
Regulatory development of geriatric medicines : to GIP or not to GIP?
Bart De Spiegeleer
Evelien Wynendaele
Nathalie Bracke
Lieselotte Veryser
Lien Taevernier
Agnes Degroote
Sofie Stalmans
A1
Journal Article
in
AGEING RESEARCH REVIEWS
2016
Skin, mucosal and blood-brain barrier kinetics of model cyclic depsipeptides : the mycotoxins beauvericin and enniatins
Lien Taevernier
Bart De Spiegeleer
Dissertation
2016
The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome
Yorick Janssens
Evelien Wynendaele
Frederick Verbeke
An Hendrix
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
C3
Conference
2016
The human microbiota in health and disease: the role of quorum sensing peptides
Evelien Wynendaele
Frederick Verbeke
Yorick Janssens
Bart De Spiegeleer
C3
Conference
2016
The mycotoxin definition reconsidered towards fungal cyclic depsipeptides
Lien Taevernier
Evelien Wynendaele
Leen De Vreese
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
2016
Topical acyclovir treatment of occult equine sarcoids: an in vitro and in vivo study
Maarten Haspeslagh
Lien Taevernier
An Maes
Lieven Vlaminck
Bart De Spiegeleer
Siska Croubels
Ann Martens
C3
Conference
2016
Topical distribution of acyclovir in normal equine skin and equine sarcoids : an in vitro study
Maarten Haspeslagh
Lien Taevernier
An Maes
Lieven Vlaminck
Bart De Spiegeleer
Siska Croubels
Ann Martens
A1
Journal Article
in
RESEARCH IN VETERINARY SCIENCE
2016
Using Tc-99m-HMPAO SPECT as tool to compare two transcranial magnetic stimulation protocols and their long-term effects in dogs
Robrecht Dockx
Chris Baeken
Lise Vlerick
Romain Duprat
Filip De Vos
Bart De Spiegeleer
André Dobbeleir
Jimmy Saunders
Ingeborgh Polis
Eric Achten
Kurt Audenaert
Kathelijne Peremans
C3
Conference
2016
2015
An analytical quality-by-design (aQbD) approach for a L-asparaginase activity method
Han Yao
Jochem Vancoillie
Matthias D'Hondt
Evelien Wynendaele
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2015
Analytical quality-by-design approach for sample treatment of BSA-containing solutions
Lien Taevernier
Evelien Wynendaele
Matthias D'Hondt
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2015
Assessment of efficacy and quality of two albendazole brands commonly used against soil-transmitted helminth infections in school children in Jimma Town, Ethiopia
Sileshi Belew Yohannes
Mestawet Getachew
Sultan Suleman Wega
Tesfaye Mohammed
Habetewold Deti
Matthias D'Hondt
Evelien Wynendaele
Zeleke Mekonnen Kurmane
Jozef Vercruysse
Luc Duchateau
Bart De Spiegeleer
Bruno Levecke
A1
Journal Article
in
PLOS NEGLECTED TROPICAL DISEASES
2015
Biomarkers to predict severity of bovine E. coli mastitis in the periparturient period: bridging the gap between genotype and phenotype
Christian Burvenich
Xanthippe Boulougouris
Carolien Rogiers
Catherine Delesalle
Luc Duchateau
Luc Peelman
Mario Van Poucke
Gianfranco Gabai
Bart De Spiegeleer
C3
Conference
2015
Blood–brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins
Mathieu Verbeken
Evelien Wynendaele
Elodie Mauchauffée
Nathalie Bracke
Sofie Stalmans
Engin Bojnik
Sandor Benyhe
Kathelijne Peremans
Ingeborgh Polis
Christian Burvenich
Albert Gjedde
Jean-François Hernandez
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2015
Cell-penetrating peptides selectively cross the blood-brain barrier in vivo
Sofie Stalmans
Nathalie Bracke
Evelien Wynendaele
Bert Gevaert
Kathelijne Peremans
Christian Burvenich
Ingeborgh Polis
Bart De Spiegeleer
A1
Journal Article
in
PLOS ONE
2015
Classification of peptides according to their blood-brain barrier influx
Sofie Stalmans
Bert Gevaert
Evelien Wynendaele
Joachim Nielandt
Guy De Tré
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PROTEIN AND PEPTIDE LETTERS
2015
Communication of quorum sensing peptides with breast cancer cells
Frederick Verbeke
Evelien Wynendaele
Marianne Lauwers
An Hendrix
Christian Burvenich
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
C3
Conference
2015
Crosstalk between the microbiome and cancer cells by quorum sensing peptides
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Burvenich
Kathelijne Peremans
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2015
Effect of ketamine on the regional cerebral blood flow and binding index of the 5-HT2A receptor radioligand 123I-R91150 in the canine brain
Tim Waelbers
Ingeborgh Polis
Simon Vermeire
Andre Dobbeleir
Jos Eersels
Bart De Spiegeleer
Kurt Audenaert
Kathelijne Peremans
A1
Journal Article
in
JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH
2015
Enniatin-containing solutions for oromucosal use: quality-by-design ex-vivo transmucosal risk assessment of composition variability
Lien Taevernier
Sven Detroyer
Lieselotte Veryser
Bart De Spiegeleer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2015
Evaluation of local tolerance of a plant extract by the slug mucosal irritation (SMI) assay
Lieselotte Veryser
Joke Lenoir
Jente Boonen
Nathalie Bracke
Evelien Wynendaele
Els Adriaens
Hans Nelis
Bram De Wever
Jean Paul Remon
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF TOXICOLOGICAL EDUCATION
2015
Gas chromatographic method for the determination of lumefantrine in antimalarial finished pharmaceutical products
Sultan Suleman Wega
Yannick Verheust
Ann Dumoulin
Evelien Wynendaele
Matthias D'Hondt
Kirsten Vandercruyssen
Lieselotte Veryser
Luc Duchateau
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF FOOD AND DRUG ANALYSIS
2015
Implementation of a single quad MS detector in high-throughput transdermal research of plant extracts
Lieselotte Veryser
Lien Taevernier
Nathalie Roche
Phillip Blondeel
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2015
Onbeschikbaarheid van geneesmiddelen in het ziekenhuis: beheer, oorzaken en budgetimpact
Barbara Claus
Kim Pauwels
Mariëlle Baert
Jan Depoorter
Elfi De Weerdt
Koen Boussery
Bart De Spiegeleer
SABRINA COMMEYNE
A4
Journal Article
in
FARMACEUTISCH TIJDSCHRIFT VOOR BELGIE [1971]
2015
Peptide profiling of internet obtained Cerebrolysin using HPLC-ESI-IT & UHPLC-Q-IM-TOF mass spectrometry
Bert Gevaert
Matthias D'Hondt
Nathalie Bracke
Han Yao
Evelien Wynendaele
Johannes Petrus Cornelis Vissers
Martin De Cecco
Jan Claereboudt
Bart De Spiegeleer
C3
Conference
2015
Peptide profiling of internet-obtained cerebrolysin using high performance liquid chromatography–electrospray ionization ion trap and ultra high performance liquid chromatography–ion mobility–quadrupole time of flight mass spectrometry
Bert Gevaert
Matthias D'Hondt
Nathalie Bracke
Han Yao
Evelien Wynendaele
Johannes Petrus Cornelis Vissers
Martin De Cecco
Jan Claereboudt
Bart De Spiegeleer
A1
Journal Article
in
DRUG TESTING AND ANALYSIS
2015
Phase I dose-escalation study evaluating the safety and pharmacokinetics of oral artesunate in patients with advanced hepatocullular carcinoma (DESPARTH trial)
Yves-Paul Vandewynckel
K Rombauts
Xavier Verhelst
Lucas Van Bortel
Bart De Spiegeleer
Anja Geerts
Hans Van Vlierberghe
C3
Conference
2015
Quality evaluation of synthetic quorum sensing peptides used in R&D
Frederick Verbeke
Evelien Wynendaele
Sarah Braet
Matthias D'Hondt
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2015
Quality-by-design risk assessment of topical formulation variability
Lien Taevernier
Sven Detroyer
Lieselotte Veryser
Bart De Spiegeleer
C3
Conference
2015
Quorum sensing peptides selectively penetrate the blood-brain barrier
Evelien Wynendaele
Frederick Verbeke
Sofie Stalmans
Bert Gevaert
Yorick Janssens
Christophe Van De Wiele
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PLOS ONE
2015
Reactive oxygen species generation by bovine blood neutrophils with different CXCR1 (IL8RA) genotype following Interleukin-8 incubation
Joren Verbeke
Xanthippe Boulougouris
Carolien Rogiers
Christian Burvenich
Luc Peelman
Bart De Spiegeleer
Sarne De Vliegher
A1
Journal Article
in
BMC VETERINARY RESEARCH
2015
Regional cerebral blood flow changes after accelerated repetitive transcranial magnetic stimulation of the canine frontal cortex
Robrecht Dockx
Chris Baeken
Romain Duprat
Filip De Vos
Bart De Spiegeleer
André Dobbeleir
Jimmy Saunders
Ingeborgh Polis
Kurt Audenaert
Kathelijne Peremans
C3
Conference
2015
Surface acoustic wave biosensor as a functional quality method in pharmaceutics
Nathalie Bracke
Sophia Barhdadi
Evelien Wynendaele
Bert Gevaert
Matthias D'Hondt
Bart De Spiegeleer
A1
Journal Article
in
SENSORS AND ACTUATORS B-CHEMICAL
2015
The blood-brain barrier (BBB) permeability properties of plant N-alkylamides
Lieselotte Veryser
Evelien Wynendaele
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2015
The influence of the acyl chain on the transdermal penetration-enhancing effect of synthetic phytoceramides
Lieselotte Veryser
Jente Boonen
Lien Taevernier
Joren Guillaume
Martijn Risseeuw
Syed Nisar Hussain Shah
Nathalie Roche
Serge Van Calenbergh
Bart De Spiegeleer
A1
Journal Article
in
SKIN PHARMACOLOGY AND PHYSIOLOGY
2015
The quality of paediatric medicines supplied by private wholesalers in Kinshasa, DRC
Raffaella Ravinetto
Daniel Ngeleka Mutolo
Bart De Spiegeleer
Roland Marini
Epco Hasker
Benedetta Schiavetti
C3
Conference
2015
The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro
Bart De Spiegeleer
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Burvenich
Kathelijne Peremans
Olivier De Wever
Marc Bracke
Evelien Wynendaele
A1
Journal Article
in
PLOS ONE
2015
The use of UHPLC coupled to single quad MS detection in Franz diffusion cell methodologies
Lieselotte Veryser
Lien Taevernier
Evelien Wynendaele
Nathalie Roche
Bart De Spiegeleer
C3
Conference
2015
To what extent do cell-penetrating peptides selectively cross the blood-brain barrier?
Sofie Stalmans
Bart De Spiegeleer
Dissertation
2015
Towards a peptide implant: analytics, dry heat behavior and functional characterization
Matthias D'Hondt
Bart De Spiegeleer
Dissertation
2015
Two phenotypes of bovine neutrophils during lactation: fiction or fact?
Xanthippe Boulougouris
Carolien Rogiers
Catherine Delesalle
Luc Duchateau
Luc Peelman
Mario Van Poucke
Bart De Spiegeleer
Christian Burvenich
C3
Conference
2015
2014
A preliminary analysis of the quality of pediatric medicines supplied by private wholesalers in Kinshasa, DRC
Benedetta Schiavetti
Daniel Ngeleka Mutolo
Roland Marini Djang'Eing'A
Bart De Spiegeleer
Epco Hasker
Josiane Van Der Elst
C3
Conference
2014
Adsorption of cyclic depsipeptide mycotoxins to glass
Lien Taevernier
Stijn Vansteelandt
Bart De Spiegeleer
C1
Conference
2014
Analytical characterisation of NOTA-modified somatropins
Nathalie Bracke
Evelien Wynendaele
Matthias D'Hondt
Rob Haselberg
Govert W Somsen
Ewald Pauwels
Christophe Van De Wiele
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2014
Are plant N-alkylamide cosmenutriceuticals also active in the central nervous system?
Lieselotte Veryser
Evelien Wynendaele
Lien Taevernier
Frederick Verbeke
Tanmayee Joshi
Pratima Tatke
Bart De Spiegeleer
C3
Conference
2014
Blood-brain barrier transport of short proline-rich antimicrobial peptides
Sofie Stalmans
Evelien Wynendaele
Nathalie Bracke
Daniel Knappe
Ralf Hoffmann
Kathelijne Peremans
Ingeborgh Polis
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PROTEIN AND PEPTIDE LETTERS
2014
Brain SPECT in the impulsive-agressive dog
Kathelijne Peremans
Simon Vermeire
Tim Waelbers
Eva Vandermeulen
André Dobbeleir
Bart De Spiegeleer
Kurt Audenaert
Bookchapter
in
PET and SPECT in psychiatry
2014
Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Burvenich
Kathelijne Peremans
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
C3
Conference
2014
Derringer desirability and kinetic plot LC-column comparison approach for MS-compatible lipopeptide analysis
Matthias D'Hondt
Frederick Verbeke
Sofie Stalmans
Bert Gevaert
Evelien Wynendaele
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2014
Development of geriatric medicines: to GIP or not to GIP?
Sofie Stalmans
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2014
Development of peptide and protein based radiopharmaceuticals
Evelien Wynendaele
Nathalie Bracke
Sofie Stalmans
Bart De Spiegeleer
A1
Journal Article
in
CURRENT PHARMACEUTICAL DESIGN
2014
Do cell-penetrating peptides cross the blood-brain barrier
Sofie Stalmans
Evelien Wynendaele
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2014
Dry heat forced degradation of buserelin peptide: kinetics and degradant profiling
Matthias D'Hondt
Maria Fedorova
Chien-Yu Peng
Bert Gevaert
Lien Taevernier
Ralf Hoffmann
Bart De Spiegeleer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2014
Exploration of quorum sensing peptides: the missing link between microbiome and cancer outcome?
Evelien Wynendaele
Bart De Spiegeleer
Dissertation
2014
Exploration of the peptide drug space
Bert Gevaert
Evelien Wynendaele
Mathieu Verbeken
Matthias D'Hondt
Sofie Stalmans
Kathelijne Peremans
Christian Burvenich
Catherine Delesalle
Bart De Spiegeleer
C3
Conference
2014
Flatworm models in pharmacological research: the importance of compound stability testing
Sofie Stalmans
Maxime Willems
Els Adriaens
Jean Paul Remon
Matthias D'Hondt
Bart De Spiegeleer
A1
Journal Article
in
REGULATORY TOXICOLOGY AND PHARMACOLOGY
2014
How does the human microbiome affect cancer outcome?
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Burvenich
Kathelijne Peremans
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
C3
Conference
2014
How the exploration of the chemical space of cell-penetrating peptides helps to understand their functionality
Sofie Stalmans
Evelien Wynendaele
Bart De Spiegeleer
C3
Conference
2014
Human skin kinetics of cyclic depsipeptide mycotoxins
Lien Taevernier
Lieselotte Veryser
Nathalie Roche
Bart De Spiegeleer
C3
Conference
2014
Identification of a microscopically selected microorganism in milk samples
Nathalie Bracke
Mario Van Poucke
Bram Baert
Evelien Wynendaele
Lobke De Bels
Wim Van Den Broeck
Luc Peelman
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF DAIRY SCIENCE
2014
Investigation of active pharmaceutical ingredient loss in pharmaceutical compounding of capsules
Matthias D'Hondt
Evelien Wynendaele
Kirsten Vandercruyssen
Tieneke Bauters
Johan Vandenbroucke
Steven Mullens
Chris Vervaet
Jean Paul Remon
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2014
LC-UV/MS quality analytics of paediatric artemether formulations
Kirsten Vandercruyssen
Matthias D'Hondt
Valentijn Vergote
Herwig Jansen
Christian Burvenich
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2014
N-alkylamides : from plant to brain
Lieselotte Veryser
Evelien Wynendaele
Lien Taevernier
Frederick Verbeke
Tanmayee Joshi
Pratima Tatke
Bart De Spiegeleer
A2
Journal Article
in
FUNCTIONAL FOODS IN HEALTH AND DISEASE
2014
Pharmacopeial characterization of asparaginase
Han Yao
Matthias D'Hondt
Yves Benoit
Tieneke Bauters
Bart De Spiegeleer
C3
Conference
2014
Quality of medicines commonly used in the treatment of soil transmitted helminths and Giardia in Ethiopia: a nationwide survey
Sultan Suleman Wega
Gemechu Zeleke
Habtewold Deti
Zeleke Mekonnen Kurmane
Luc Duchateau
Bruno Levecke
Jozef Vercruysse
Matthias D'Hondt
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
PLOS NEGLECTED TROPICAL DISEASES
2014
Quantitative transdermal behavior of pellitorine from Anacyclus pyrethrum
Lieselotte Veryser
Lien Taevernier
Nathalie Roche
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PHYTOMEDICINE
2014
Quorum sensing peptides: missing link between microbiome and health?
Evelien Wynendaele
Frederick Verbeke
Matthias D'Hondt
An Hendrix
Christophe Van De Wiele
Christian Burvenich
Kathelijne Peremans
Olivier De Wever
Marc Bracke
Bart De Spiegeleer
C3
Conference
2014
Raman model development for the protein conformational state classification in different freeze-dried formulations
Sigrid Pieters
Jean-Michel Roger
Thomas De Beer
Matthias D'Hondt
Bart De Spiegeleer
Yvan Vander Heyden
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2014
Related impurities in peptide medicines
Matthias D'Hondt
Nathalie Bracke
Lien Taevernier
Bert Gevaert
Frederick Verbeke
Evelien Wynendaele
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2014
Risk evaluation of impurities in topical excipients: the acetol case
Jente Boonen
Lieselotte Veryser
Lien Taevernier
Nathalie Roche
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2014
Similars for biologics and ATMPs: quo vadis?
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2014
Solid-state heat stability of peptides : kinetics and mechanisms
Matthias D'Hondt
Chien-Yu Peng
Ralf Hoffmann
Bart De Spiegeleer
C3
Conference
2014
Surface acoustic wave biosensor as a functional-quality method in pharmaceutics
Nathalie Bracke
Evelien Wynendaele
Bert Gevaert
Bart De Spiegeleer
C3
Conference
2014
Surface acoustic wave biosensor as an analytical tool in pharmaceutics : a quality by design approach
Nathalie Bracke
Evelien Wynendaele
Bert Gevaert
Bart De Spiegeleer
C3
Conference
2014
Synthesis and degradation impurities in peptide drugs
Matthias D'Hondt
Bart De Spiegeleer
C3
Conference
2014
The effect of morphine on regional cerebral blood flow measured by 99mTc-ECD SPECT in dogs
Antita Adriaens
Kathelijne Peremans
Tim Waelbers
Eva Vandermeulen
Siska Croubels
Luc Duchateau
André Dobbeleir
Kurt Audenaert
Jos Eersels
Simon Vermeire
Bart De Spiegeleer
Ingeborgh Polis
A1
Journal Article
in
PLOS ONE
2014
The effect of prolonged exposure to morphine on canine cerebral 5-HT2A receptors measured with 123I-R91150 SPECT
Antita Adriaens
Ingeborgh Polis
Simon Vermeire
Tim Waelbers
Siska Croubels
Luc Duchateau
Sylvia Van Dorpe
Jos Eersels
Bart De Spiegeleer
Kathelijne Peremans
A1
Journal Article
in
EUROPEAN NEUROPSYCHOPHARMACOLOGY
2014
The moving boundaries in starting materials: from small molecules to biopharma and ATMPs
Matthias D'Hondt
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2014
The possible role of somatropin derivatives as a theranostic in oncology
Nathalie Bracke
Evelien Wynendaele
Sophia Barhdadi
Christophe Van De Wiele
Bart De Spiegeleer
C3
Conference
2014
UHPLC-MS/MS method for the determination of the cyclic depsipeptide mycotoxins beauvericin and enniatins in in vitro transdermal experiments
Lien Taevernier
Lieselotte Veryser
Kirsten Vandercruyssen
Matthias D'Hondt
Stijn Vansteelandt
Sarah De Saeger
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2014
2013
5-HT2A Receptors in the feline brain: 123I-5-I-R91150 kinetics and the influence of ketamine measured with micro-SPECT
Tim Waelbers
Ingeborgh Polis
Simon Vermeire
André Dobbeleir
Jos Eersels
Bart De Spiegeleer
Kurt Audenaert
Guido Slegers
Kathelijne Peremans
A1
Journal Article
in
JOURNAL OF NUCLEAR MEDICINE
2013
A critical quality parameter in quantitative fused-core chromatography : the injection volume
Jente Boonen
Matthias D'Hondt
Lieselotte Veryser
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2013
A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products
Sultan Suleman Wega
Kirsten Vandercruyssen
Evelien Wynendaele
Matthias D'Hondt
Nathalie Bracke
Luc Duchateau
Christian Burvenich
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
MALARIA JOURNAL
2013
Analytical QbD development of a pharmacopeial monograph for the anticancer drug asparaginase
Han Yao
Matthias D'Hondt
Pieter-Jan Van Bockstal
Yves Benoit
Tieneke Bauters
Bart De Spiegeleer
C3
Conference
2013
Androgenic and spermatogenic activity of alkylamide-rich ethanol solution extract of Anacyclus pyrethrum DC
Vikas Sharma
Jente Boonen
Bart De Spiegeleer
Vinot Dixit
A1
Journal Article
in
PHYTOTHERAPY RESEARCH
2013
Buserelin: a solid state peptide degradation kinetic and mechanistic study
Matthias D'Hondt
Chien-Yu Peng
Ralf Hoffmann
Bart De Spiegeleer
C3
Conference
2013
Chemical-functional diversity in cell-penetrating peptides
Sofie Stalmans
Evelien Wynendaele
Nathalie Bracke
Bert Gevaert
Matthias D'Hondt
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PLOS ONE
2013
Interaction between the serotonergic and opioid system : effect of 10 days oral morphine on the canine cerebral 5-HT2A receptor density measured with SPECT
Kathelijne Peremans
Antita Adriaens
Eva Vandermeulen
Simon Vermeire
Tim Waelbers
Jos Eersels
Luc Duchateau
André Dobbeleir
Bart De Spiegeleer
Kurt Audenaert
Ingeborgh Polis
C3
Conference
2013
Morphine and the canine brain : the influence of morphine on cerebral perfusion and 5-HT2A receptors
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
Dissertation
2013
Normal regional distribution of cerebral blood flow in dogs: comparison between 99mTc-ethylcysteinate dimer and 99mTc-hexamethylpropylene amine oxime single photon emission computed tomography
Antita Adriaens
Ingeborgh Polis
Tim Waelbers
Eva Vandermeulen
André Dobbeleir
Bart De Spiegeleer
Kathelijne Peremans
A1
Journal Article
in
VETERINARY RADIOLOGY & ULTRASOUND
2013
Quantitative pretreatment VOI analysis of liver metastases 99mTc-MAA SPECT/CT and FDG PET/CT in relation with treatment response to SIRT
Christophe Van De Wiele
K Stellamans
E Brugman
Gilles Mees
Bart De Spiegeleer
Yves D'Asseler
L Beels
A Maes
A1
Journal Article
in
NUKLEARMEDIZIN-NUCLEAR MEDICINE
2013
Quorumpeps database : chemical space, microbial origin and functionality of quorum sensing peptides
Evelien Wynendaele
Antoon Bronselaer
Joachim Nielandt
Matthias D'Hondt
Sofie Stalmans
Nathalie Bracke
Frederick Verbeke
Christophe Van De Wiele
Guy De Tré
Bart De Spiegeleer
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2013
Raman spectroscopy and multivariate analysis for the rapid discrimination between native-like and non-native states in freeze-dried protein formulations
Sigrid Pieters
Yvan Vander Heyden
Jean-Michel Roger
Matthias D'Hondt
Laurent Hansen
Bernard Palagos
Bart De Spiegeleer
Jean Paul Remon
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2013
Reversed-phase fused-core HPLC modeling of peptides
Matthias D'Hondt
Bert Gevaert
Sofie Stalmans
Sylvia Van Dorpe
Evelien Wynendaele
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2013
Skin penetration enhancing properties of the plant N-alkylamide spilanthol
Bart De Spiegeleer
Jente Boonen
Svetlana Malysheva
José Diana Di Mavungu
Sarah De Saeger
Nathalie Roche
Phillip Blondeel
Lien Taevernier
Lieselotte Veryser
A1
Journal Article
in
JOURNAL OF ETHNOPHARMACOLOGY
2013
Somatropin (rhGH) functional quality characterization by LC/CE-MS and SAW (Surface Acoustic Wave) biosensor techniques
Nathalie Bracke
Evelien Wynendaele
Rob Haselberg
Govert Somsen
Sophia Barhdadi
Bart De Spiegeleer
C3
Conference
2013
Surface acoustic wave technology as a tool for functional quality characterization of new compounds and biosimilars
Nathalie Bracke
Evelien Wynendaele
Christophe Van De Wiele
Bart De Spiegeleer
C3
Conference
2013
The use of the HiSPECT bone scan in canine flexor enthesopathy and coronoid pathology
Kathelijne Peremans
Luc Duchateau
Simon Vermeire
Eva Vandermeulen
André Dobbeleir
Ingrid Gielen
Ingeborgh Polis
Bernadette Van Ryssen
Evelien de Bakker
Jimmy Saunders
Bart De Spiegeleer
Kees Dik
A1
Journal Article
in
RESEARCH IN VETERINARY SCIENCE
2013
Time dependent effects of a single bolus morphine on canine regional brain perfusion
Ingeborgh Polis
Antita Adriaens
Eva Vandermeulen
Simon Vermeire
Tim Waelbers
Bart De Spiegeleer
André Dobbeleir
Jos Eersels
Kurt Audenaert
Kathelijne Peremans
C3
Conference
2013
Transdermal evaluation of caffeine in different formulations and excipients
Lieselotte Veryser
Jente Boonen
Els Mehuys
Nathalie Roche
Jean Paul Remon
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF CAFFEINE RESEARCH
2013
Transsplenic portal scintigraphy using 99mTc-pertechnetate for the diagnosis of portosystemic shunts in cats: a retrospective review of 12 patients
Eva Vandermeulen
Anaïs Combes
Hilde De Rooster
Ingeborgh Polis
Bart De Spiegeleer
Jimmy Saunders
Kathelijne Peremans
A1
Journal Article
in
JOURNAL OF FELINE MEDICINE AND SURGERY
2013
2012
Alkamid database: chemistry, occurrence and functionality of plant N-alkylamides
Jente Boonen
Antoon Bronselaer
Joachim Nielandt
Lieselotte Veryser
Guy De Tré
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF ETHNOPHARMACOLOGY
2012
Analytical characterization of the blood-brain barrier transport of peptides
Sylvia Van Dorpe
Bart De Spiegeleer
Dissertation
2012
Api88 is a novel antibacterial designer peptide to treat systemic infections with multidrug-resistant Gram-negative pathogens
Patricia Czihal
Daniel Knappe
Stefanie Fritsche
Michael Zahn
Nicole Berthold
Stefania Piantavigna
Uwe Müller
Sylvia Van Dorpe
Nicole Herth
Annegret Binas
Gabriele Köhler
Bart De Spiegeleer
Lisandra L Martin
Oliver Nolte
Norbert Sträter
Gottfried Alber
Ralf Hoffmann
A1
Journal Article
in
ACS CHEMICAL BIOLOGY
2012
Blood-brain barrier modelling of bioactive peptides
Bart De Spiegeleer
Matthias D'Hondt
Sofie Stalmans
Sylvia Van Dorpe
C3
Conference
2012
Brainpeps: the blood-brain barrier peptide database
Sylvia Van Dorpe
Antoon Bronselaer
Joachim Nielandt
Sofie Stalmans
Evelien Wynendaele
Kurt Audenaert
Christophe Van De Wiele
Christian Burvenich
Kathelijne Peremans
Hung Hsuchou
Guy De Tré
Bart De Spiegeleer
A1
Journal Article
in
BRAIN STRUCTURE & FUNCTION
2012
Chiral nickel(II) complexes in the preparation of C-11- and F-18-labelled enantiomerically pure alpha-amino acids
Alexander Popkov
Bart De Spiegeleer
A1
Journal Article
in
DALTON TRANSACTIONS
2012
Compromised neutrophil function and bovine E. coli mastitis: is C5a the missing link?
Mieke Stevens
Bart De Spiegeleer
Luc Peelman
Xanthippe Boulougouris
Anthony Capuco
Christian Burvenich
A1
Journal Article
in
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
2012
Differential microRNA expression analysis in blastocysts by whole mount in situ hybridization and reverse transcription quantitative polymerase chain reaction on laser capture microdissection samples
Karen Goossens
Ward De Spiegelaere
Mieke Stevens
Christian Burvenich
Bart De Spiegeleer
Pieter Cornillie
Alex Van Zeveren
Ann Van Soom
Luc Peelman
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2012
Dry heat stress stability of model peptide: buserelin
Matthias D'Hondt
Bart De Spiegeleer
C3
Conference
2012
Exploring the Brainpeps database
Sofie Stalmans
Matthias D'Hondt
Evelien Wynendaele
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2012
Exploring the chemical-functional space of cell-penetrating peptides
Sofie Stalmans
Evelien Wynendaele
Bart De Spiegeleer
C3
Conference
2012
Functional quality of peptide drugs
Mathieu Verbeken
Nathalie Bracke
Bart De Spiegeleer
C3
Conference
2012
Functional quality of spilanthol, a plant N-alkylamide for dermal applications
Jente Boonen
Bart De Spiegeleer
Dissertation
2012
Gene expression analysis in specific cell populations of bovine blastocysts using laser capture microdissection
Ward De Spiegelaere
Karen Goossens
Mieke Stevens
Ann Van Soom
Luc Peelman
Christian Burvenich
Bart De Spiegeleer
Pieter Cornillie
C3
Conference
2012
Human skin penetration of selected model mycotoxins
Jente Boonen
Svetlana Malysheva
Lien Taevernier
José Diana Di Mavungu
Sarah De Saeger
Bart De Spiegeleer
A1
Journal Article
in
TOXICOLOGY
2012
Improved positive electrospray ionization of patulin by adduct formation: usefulness in liquid chromatography-tandem mass spectrometry multi-mycotoxin analysis
Svetlana Malysheva
José Diana Di Mavungu
Jente Boonen
Bart De Spiegeleer
Irina Y Goryacheva
Lynn Vanhaecke
Sarah De Saeger
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY A
2012
In vitro metabolic stability of iodinated obestatin peptides
Bart De Spiegeleer
Sylvia Van Dorpe
Valentijn Vergote
Evelien Wynendaele
Ewald Pauwels
Christophe Van De Wiele
Pablo Garcia-Solis
Juan Carlos Solis-Sainz
A1
Journal Article
in
PEPTIDES
2012
Increase of the transdermal penetration of testosterone by miconazole nitrate
Bram Baert
Nathalie Roche
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
ARCHIVES OF PHARMACAL RESEARCH
2012
Influence of variability in starting materials quality on stability of finished drug products: a quality-by-design factor and response
Matthias D'Hondt
Evelien Wynendaele
Tieneke Bauters
Johan Vandenbroucke
Hugo Robays
Bart De Spiegeleer
C3
Conference
2012
Ketamine decreases the cerebral binding index of the selective 5-HT2A receptor radioligand 123I-R91150 measured with µSPECT in cats
Tim Waelbers
Ingeborgh Polis
Simon Vermeire
André Dobbeleir
J Eerssels
Bart De Spiegeleer
Kurt Audenaert
Guido Slegers
Kathelijne Peremans
C3
Conference
2012
LC-MS N-alkylamide profiling of an ethanolic Anacyclus pyrethrum root extract
Jente Boonen
Vikas Sharma
Vinod Dixit
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PLANTA MEDICA
2012
LC-MS N-alkylamide profiling of an ethanolic Anacyclus pyrethrum root extract
Vikas Sharma
Jente Boonen
Bart De Spiegeleer
Vinod K Dixit
C3
Conference
2012
Molecular weights under discussion?
Bart De Spiegeleer
Matthias D'Hondt
A2
Journal Article
in
PHARMEUROPA
2012
Penetration enhancing effect of phytoceramides
Lieselotte Veryser
Jente Boonen
Joren Guillaume
Martijn Risseeuw
Serge Van Calenbergh
Bart De Spiegeleer
C3
Conference
2012
Receptor and blood-brain barrier characterisation of opioid peptides in drug research and early development
Bart De Spiegeleer
Sofie Stalmans
Evelien Wynendaele
Nathalie Bracke
Mathieu Verbeken
Kathelijne Peremans
Ingeborgh Polis
Christian Burvenich
C3
Conference
2012
Receptor and blood-brain barrier characterization of opioid peptides in drug research and early development
Mathieu Verbeken
Sofie Stalmans
Evelien Wynendaele
Nathalie Bracke
Bert Gevaert
Kathelijne Peremans
Ingeborgh Polis
Christian Burvenich
Bart De Spiegeleer
C3
Conference
2012
Relative response factor determination of β-artemether degradants by a dry heat stress approach
Bart De Spiegeleer
Matthias D'Hondt
Elien Vangheluwe
Kirsten Vandercruyssen
Herwig Jansen
Ilse Koijen
Jacques Van Gompel
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2012
SIRT of liver metastases: physiological and pathophysiological considerations
Christophe Van De Wiele
Alex Maes
Eddy Brugman
YVES D'ASSELER
Bart De Spiegeleer
Gilles Mees
Karin Stellamans
A1
Journal Article
in
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2012
Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder
Simon Vermeire
Kurt Audenaert
Rudy De Meester
Eva Vandermeulen
Tim Waelbers
Bart De Spiegeleer
Jos Eersels
André Dobbeleir
Kathelijne Peremans
A1
Journal Article
in
PSYCHIATRY RESEARCH-NEUROIMAGING
2012
Skin penetration enhancing effect of the plant N-alkylamide spilanthol
Bart De Spiegeleer
Jente Boonen
Lieselotte Veryser
Lien Taevernier
Svetlana Malysheva
José Diana Di Mavungu
Sarah De Saeger
C3
Conference
2012
Stability of extemporaneously prepared cytarabine, methotrexate sodium, and methylprednisolone sodium succinate
Matthias D'Hondt
Elien Vangheluwe
Sylvia Van Dorpe
Jente Boonen
Tieneke Bauters
BRIGITTE PELFRENE
Johan Vandenbroucke
Hugo Robays
Bart De Spiegeleer
A1
Journal Article
in
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
2012
Surface acoustic wave technology as a tool for functional characterization of new compounds
Nathalie Bracke
Laurens Deneve
Bart De Spiegeleer
C3
Conference
2012
Targeting the S1 and S3 subsite of trypsin with unnatural cationic amino acids generates antimicrobial peptides with potential for oral administration
Rasmus Karstad
Geir Isaksen
Evelien Wynendaele
Yngve Guttormsen
Bart De Spiegeleer
Bjorn-Olav Brandsdal
John Sigurd Svendsen
Johan Svenson
A1
Journal Article
in
JOURNAL OF MEDICINAL CHEMISTRY
2012
The influence of chronic morphine on the canine cerebral 5-HT2A receptor availability measured with SPECT
Antita Adriaens
Ingeborgh Polis
Simon Vermeire
Eva Vandermeulen
Tim Waelbers
Jos Eersels
André Dobbeleir
Luc Duchateau
Sylvia Van Dorpe
Bart De Spiegeleer
Kathelijne Peremans
C3
Conference
2012
The influence of ketamine on the regional cerebral perfusion and on the binding index of the selective 5-HT2A receptor radioligand 123I-R91150 measured with SPECT in the canine brain
Tim Waelbers
Ingeborgh Polis
Simon Vermeire
André Dobbeleir
J Eerssels
Bart De Spiegeleer
Kurt Audenaert
Guido Slegers
Kathelijne Peremans
C3
Conference
2012
The influence of morphine on cerebral 5-HT2A receptor availability in dogs: a SPECT study
Antita Adriaens
Ingeborgh Polis
Simon Vermeire
Tim Waelbers
Luc Duchateau
Stanislas Sys
Sylvia Van Dorpe
Jos Eersels
Bart De Spiegeleer
Kathelijne Peremans
A1
Journal Article
in
JOURNAL OF NUCLEAR MEDICINE
2012
The influence of peptide impurity profiles on functional tissue-organ bath response: the 11-mer peptide INSL6[151-161] case
Mathieu Verbeken
Evelien Wynendaele
Romain Lefebvre
Els Goossens
Bart De Spiegeleer
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2012
The potential role of quorum-sensing peptides in oncology
Evelien Wynendaele
Ewald Pauwels
Christophe Van De Wiele
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
MEDICAL HYPOTHESES
2012
Transdermal penetration enhancing effect of the N-alkylamide spilanthol
Jente Boonen
Lieselotte Veryser
Lien Taevernier
Nathalie Roche
Bart De Spiegeleer
C3
Conference
2012
Variation of the net charge, lipophilicity, and side chain flexibility in Dmt¹-DALDA: effect on opioid activity and biodistribution
Alexandre Novoa
Sylvia Van Dorpe
Evelien Wynendaele
Mariana Spetea
Nathalie Bracke
Sofie Stalmans
Cecilia Betti
Nga N Chung
Carole Lemieux
Johannes Zuegg
Matthew A Cooper
Dirk Tourwé
Bart De Spiegeleer
Peter W Schiller
Steven Ballet
A1
Journal Article
in
JOURNAL OF MEDICINAL CHEMISTRY
2012
2011
ADME behaviour of some Dmt-DALDA-peptide derivatives
Sylvia Van Dorpe
Iris Vandenbroeck
Evelien Wynendaele
Mathieu Verbeken
Alexandre Novoa
Dirk Tourwé
Steven Ballet
Bart De Spiegeleer
C3
Conference
2011
Anaphylatoxin C5a-induced toll-like receptor 4 signaling in bovine neutrophils
Mieke Stevens
Mario Van Poucke
Luc Peelman
P Rainard
Bart De Spiegeleer
Carolien Rogiers
Gerlinde Van de Walle
Luc Duchateau
Christian Burvenich
A1
Journal Article
in
JOURNAL OF DAIRY SCIENCE
2011
Blood-brain barrier and ADME properties of selected DALDA-peptide derivatives
Sylvia Van Dorpe
Evelien Wynendaele
Christian Burvenich
Alexandre Novoa
Dirk Tourwé
Steven Ballet
Bart De Spiegeleer
C3
Conference
2011
Blood-brain barrier characteristics of opioid peptides
Sylvia Van Dorpe
Christophe Van De Wiele
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
C3
Conference
2011
Chemical-functional space exploration of plant N-alkylamides
Jente Boonen
Vikas Sharma
Vinot Dixit
Bart De Spiegeleer
C3
Conference
2011
Chemical-functional space exploration of plant N-alkylamides
Jente Boonen
Vikas Sharma
Vinot Dixit
Bart De Spiegeleer
C3
Conference
2011
Classification of quorum-sensing peptides
Evelien Wynendaele
Ewald Pauwels
Christophe Van De Wiele
Antoon Bronselaer
Guy De Tré
Bart De Spiegeleer
C3
Conference
2011
Desirability function combining metabolic stability and functionality of peptides
Sylvia Van Dorpe
Antita Adriaens
Simon Vermeire
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PEPTIDE SCIENCE
2011
Development of a quorum-sensing peptide database: quorumpeps
Evelien Wynendaele
Antoon Bronselaer
Guy De Tré
Ewald Pauwels
Maxime Boucart
Christophe Van De Wiele
Bart De Spiegeleer
C3
Conference
2011
Differential gene expression of the toll-like receptor-4 cascade and neutrophil function in early- and mid-lactating dairy cows
Mieke Stevens
Luc Peelman
Bart De Spiegeleer
Adel Pezeshki
Gerlinde Van de Walle
Luc Duchateau
Christian Burvenich
A1
Journal Article
in
JOURNAL OF DAIRY SCIENCE
2011
Dry heat stress stability evaluation of casein peptide mixture
Matthias D'Hondt
Wim Demaré
Sylvia Van Dorpe
Evelien Wynendaele
Christian Burvenich
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
FOOD CHEMISTRY
2011
Functional quality of topical drugs: analytical exploration of the Franz diffusion test
Bram Baert
Bart De Spiegeleer
Dissertation
2011
Fused-core HPLC method development implemented in a short-term stability study of Triple IT solution
Matthias D'Hondt
Elien Vangheluwe
Nadia Lemeire
Tieneke Bauters
BRIGITTE PELFRENE
Johan Vandenbroucke
Hugo Robays
Bart De Spiegeleer
C3
Conference
2011
In vivo imaging of apoptosis in oncology : an update
CHRISTEL VANGESTEL
Marc Peeters
Gilles Mees
Ruth Oltenfreiter
Hendrikus H Boersma
Philip H Elsinga
Chris Reutelingsperger
Nancy Van Damme
Bart De Spiegeleer
Christophe Van De Wiele
A1
Journal Article
in
MOLECULAR IMAGING
2011
Ion mobility spectrometry as a high-throughput technique for in vitro transdermal Franz diffusion cell experiments of ibuprofen
Bram Baert
Stijn Vansteelandt
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2011
Ion mobility spectrometry of talarozole, a new azole drug, in cleaning quality control
Bram Baert
Jente Boonen
Céline Thierens
Bart De Spiegeleer
A2
Journal Article
in
INTERNATIONAL JOURNAL OF ION MOBILITY SPECTROMETRY
2011
Local skin pharmacokinetics of talarozole, a new retinoic acid metabolism blocking agent
Bram Baert
Bart De Spiegeleer
A1
Journal Article
in
SKIN PHARMACOLOGY AND PHYSIOLOGY
2011
Neuro-imaging the serotonin 2A receptor as a valid biomarker for canine behavioural disorders
Simon Vermeire
Kurt Audenaert
Rudy De Meester
Eva Vandermeulen
Tim Waelbers
Bart De Spiegeleer
Jos Eersels
André Dobbeleir
Kathelijne Peremans
A1
Journal Article
in
RESEARCH IN VETERINARY SCIENCE
2011
New N-alkylamides from Anacyclus pyrethrum
Jente Boonen
Vikas Sharma
Vinot Dixit
Bart De Spiegeleer
C3
Conference
2011
New insights into electrospray ionization of patulin
Svetlana Malysheva
José Diana Di Mavungu
Jente Boonen
Bart De Spiegeleer
Irina Yu Goryacheva
Carlos Van Peteghem
Sarah De Saeger
C3
Conference
2011
Purity profiling and the associated functional effects of a new peptide
Mathieu Verbeken
Romain Lefebvre
Goossens Els
Luyten Walter
Schoofs Liliane
Bart De Spiegeleer
C3
Conference
2011
Purity profiling of peptide drugs
Sylvia Van Dorpe
Mathieu Verbeken
Evelien Wynendaele
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF BIOANALYSIS AND BIOMEDICINE
2011
Recognition of anatomical predilection sites in canine elbow pathology on bone scans using micro-single photon emission tomography
Kathelijne Peremans
Simon Vermeire
André Dobbeleir
Ingrid Gielen
Yves Samoy
Koen Piron
Eva Vandermeulen
Guido Slegers
Henri van Bree
Bart De Spiegeleer
Kees Dik
A1
Journal Article
in
VETERINARY JOURNAL
2011
Short-term storage stability of Triple IT solution
Matthias D'Hondt
Elien Vangheluwe
Nadia Lemeire
Tieneke Bauters
BRIGITTE PELFRENE
Johan Vandenbroucke
Hugo Robays
Bart De Spiegeleer
C3
Conference
2011
Single photon emission computed tomography (SPECT) imaging of the dopamine transporter in healthy dogs
Simon Vermeire
Kurt Audenaert
Eva Vandermeulen
Tim Waelbers
Bart De Spiegeleer
Henri van Bree
Kathelijne Peremans
A1
Journal Article
in
VETERINARY JOURNAL
2011
Skin penetration of silica microparticles
Jente Boonen
Bram Baert
Jo Lambert
Bart De Spiegeleer
A1
Journal Article
in
PHARMAZIE
2011
Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats
Vikas Sharma
Jente Boonen
Nagendra Chauhan
Mayank Thakur
Bart De Spiegeleer
Vinot Dixit
A1
Journal Article
in
PHYTOMEDICINE
2011
Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats
Vikas Sharma
Jente Boonen
Nagendra Chauhan
Mayank Thakur
Bart De Spiegeleer
Vinot Dixit
C3
Conference
2011
Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine
Mathieu Verbeken
Sultan Suleman Wega
Bram Baert
Elien Vangheluwe
Sylvia Van Dorpe
Christian Burvenich
Luc Duchateau
Frans H Jansen
Bart De Spiegeleer
A1
Journal Article
in
MALARIA JOURNAL
2011
Structural modification and biological evaluation of Dmt1-DALDA analogues
Alexandre Novoa
Sylvia Van Dorpe
Evelien Wynendaele
Nga Chung
Carole Lemieux
Peter W Schiller
Dirk Tourwé
Bart De Spiegeleer
Steven Ballet
C3
Conference
2011
Variation of inflammatory dynamics and mediators in primiparous cows after intramammary challenge with Escherichia coli
Adel Pezeshki
Philippe Stordeur
Hugues Wallemacq
Frederic Schynts
Mieke Stevens
Philippe Boutet
Luc Peelman
Bart De Spiegeleer
Luc Duchateau
Fabrice Bureau
Christian Burvenich
A1
Journal Article
in
VETERINARY RESEARCH
2011
2010
A new discriminative criterion for the development of Franz diffusion tests for transdermal pharmaceuticals
Bram Baert
Jente Boonen
Christian Burvenich
Nathalie Roche
Filip Stillaert
Phillip Blondeel
Jan Van Bocxlaer
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
2010
Amide fused-core chromatography of spilanthol as applied on a patch development
Jente Boonen
Bart De Spiegeleer
C3
Conference
2010
An integrated view on how the management of the dry period length of lactating cows could affect mammary biology and defense
Adel Pezeshki
Anthony Capuco
Bart De Spiegeleer
Luc Peelman
Mieke Stevens
Robert Collier
Christian Burvenich
A1
Journal Article
in
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
2010
Analytical characterization and comparison of the blood-brain barrier permeability of eight opioid peptides
Sylvia Van Dorpe
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Jan Van Bocxlaer
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2010
Bioactive peptides as potential new drugs: from analytics to tissue bath functionality
Mathieu Verbeken
Sylvia Van Dorpe
Romain Lefebvre
Bart De Spiegeleer
C3
Conference
2010
Characterisation of modified pharmaceutical proteins: the somatropin case
Evelien Wynendaele
Daphne Wiskerke
Bart De Spiegeleer
C3
Conference
2010
Chemical quality control of peptide functionality testing in tissue baths
Mathieu Verbeken
Sylvia Van Dorpe
Romain Lefebvre
Bart De Spiegeleer
C3
Conference
2010
Comparative drugability evaluation of MOR opioid peptides in functional brain research
Bart De Spiegeleer
Sylvia Van Dorpe
Olga Jedlickova
Antita Adriaens
Simon Vermeire
Ingeborgh Polis
Kathelijne Peremans
C3
Conference
2010
Dry heat stress stability of casein hydrolysate peptide mixture
Matthias D'Hondt
Wim Demaré
Bart De Spiegeleer
C3
Conference
2010
Functional differences of iodinated obestatin peptides: in vitro metabolic stability profile
Sylvia Van Dorpe
Ingeborg Wallez
Bart De Spiegeleer
C3
Conference
2010
Functional drugability of MOR-opioid peptides through desirability
Sylvia Van Dorpe
Olga Jedlickova
Antita Adriaens
Tim Waelbers
Simon Vermeire
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
C3
Conference
2010
Functional quality analytics of peptide drugs: the obestatin case
Valentijn Vergote
Bart De Spiegeleer
Henri van Bree
Dissertation
2010
HPLC-MS characterisation of chelate modified somatropin
Evelien Wynendaele
Ewald Pauwels
Sylvia Van Dorpe
Valentijn Vergote
Christophe Van De Wiele
Bart De Spiegeleer
C3
Conference
2010
Hydrophilic interaction LC of peptides: columns comparison and clustering
Sylvia Van Dorpe
Valentijn Vergote
Adel Pezeshki
Christian Burvenich
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2010
In vitro evaluation of gentamicin- and vancomycin-containing minitablets as a replacement for fortified eye drops
S Bozdag
W Weyenberg
Els Adriaens
MMM Dhondt
V Vergote
Chris Vervaet
Kristof De Prijck
Hans Nelis
Bart De Spiegeleer
A Ludwig
Jean Paul Remon
hans nelis
A1
Journal Article
in
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
2010
Influence of injection volume and solvent strength on spilantholchromatography using RP fused-core amide stationary phase
Jente Boonen
Bart De Spiegeleer
C3
Conference
2010
LC-MS characterization and cell-binding properties of chelate modified somatropin
Evelien Wynendaele
Koen Mertens
Ewald Pauwels
Christophe Van De Wiele
Bart De Spiegeleer
C3
Conference
2010
LC-MS profiling of N-alkylamides in Spilanthes acmella extract and the transmucosal behaviour of its main bio-active spilanthol
Jente Boonen
Bram Baert
Christian Burvenich
Phillip Blondeel
Sarah De Saeger
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2010
LC-MS quality control of modified pharmaceutical proteins : the somatropin case
Evelien Wynendaele
Ewald Pauwels
Christophe Van De Wiele
Sylvia Van Dorpe
Bart De Spiegeleer
C3
Conference
2010
Metabolic fate of lactoferricin based antimicrobial peptides: effect of truncation and incorporation of amino acid analogs on the in vitro metabolic stability
Johan Svenson
Valentijn Vergote
Rasmus Karsted
Christian Burvenich
John Svendsen
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
2010
Morphine decreases 5-HT2A receptor binding measured with SPECT in the canine frontal cortex
Antita Adriaens
Simon Vermeire
Tim Waelbers
Luc Duchateau
Stanislas Sys
André Dobbeleir
Sylvia Van Dorpe
J Eersels
Bart De Spiegeleer
Kurt Audenaert
Ingeborgh Polis
Kathelijne Peremans
C3
Conference
2010
Nanoparticles : between food handling and skin penetration
Jente Boonen
Bram Baert
Bart De Spiegeleer
C3
Conference
2010
Physiology and pathophysiology of the mammary gland in primiparous cows with special emphasis to dry period length and experimental E.coli mastitis
Adel Pezeshki
Christian Burvenich
Bart De Spiegeleer
Jalil Mehrzad
Dissertation
2010
Quality analysis of salmon calcitonin in a polymeric bioadhesive pharmaceutical formulation: sample preparation optimization by DOE
Matthias D'Hondt
Sylvia Van Dorpe
Els Mehuys
Dieter Deforce
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2010
Quality analytics of internet pharmaceuticals
Bram Baert
Bart De Spiegeleer
A1
Journal Article
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2010
Serotonin 2A receptor imaging in canine behavioural disorders : an animal model for human psychiatric disorders
Simon Vermeire
Kurt Audenaert
Rudy De Meester
Eva Vandermeulen
Tim Waelbers
Bart De Spiegeleer
Jos Eersels
André Dobbeleir
Kathelijne Peremans
C3
Conference
2010
The influence of morphine on 5-HT2A receptor availability using SPECT: a preliminary study in dogs
Antita Adriaens
Simon Vermeire
Tim Waelbers
Luc Duchateau
Stanislas Sys
Sylvia Van Dorpe
Jos Eersels
Bart De Spiegeleer
Kathelijne Peremans
Ingeborgh Polis
C3
Conference
2010
The metabolisation of different iodinated peptide species
Bart De Spiegeleer
Sylvia Van Dorpe
Ewald Pauwels
C3
Conference
2010
The metabolisation of different iodinated peptide species
Bart De Spiegeleer
Sylvia Van Dorpe
Ewald Pauwels
C3
Conference
2010
Transdermal behaviour of the N-alkylamide spilanthol (affinin) from Spilanthes acmella (Compositae) extracts
Jente Boonen
Bart De Spiegeleer
Bram Baert
Nathalie Roche
Christian Burvenich
A1
Journal Article
in
JOURNAL OF ETHNOPHARMACOLOGY
2010
Vancomycin release from poly(D,L-lactic acid) spray-coated hydroxyapatite fibers
Matthieu Ravelingien
Steven Mullens
Jan Luyten
Matthias D'Hondt
Jente Boonen
Bart De Spiegeleer
Tom Coenye
Chris Vervaet
Jean Paul Remon
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2010
2009
Adsorption of peptides at the sample drying step: influence of solvent evaporation technique, vial material and solution additive
Adel Pezeshki
Valentijn Vergote
Sylvia Van Dorpe
Bram Baert
Christian Burvenich
Alexander Popkov
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2009
Analytical characterization of the BBB functionality of the opioid-peptides EM-1, EM-2 and CTAP.
Sylvia Van Dorpe
Nathalie Pintelon
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Weihong Pan
Christian Burvenich
Bart De Spiegeleer
C3
Conference
2009
Analytical profiling, modeling and transdermal/transmucosal characteristics of bioactive N-alkylamides
Bart De Spiegeleer
Jente Boonen
Christian Burvenich
Phillip Blondeel
Bram Baert
C3
Conference
2009
Analytical, biopharmaceutical and regulatory evaluation of topical testosterone preparations
Bram Baert
Sudakar Annavarapu
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
European Journal of Pharmaceutics and Biopharmaceutics
2009
Central administration of obestatin fails to show inhibitory effects on food and water intake in mice
Annemie Van Dijck
Debby Van Dam
Valentijn Vergote
Bart De Spiegeleer
Walter Luyten
Liliane Schoofs
Peter Paul De Deyn
A1
Journal Article
in
Regulatory Peptides
2009
Chemical and metabolic stability of lactoferricin-based cationic antimicrobial tripeptides
Valentijn Vergote
Johan Svenson
Christian Burvenich
Rasmus Karstad
Bart De Spiegeleer
C3
Conference
2009
Chemical and metabolic stability of lactoferricin-derived cationic antimicrobial tripeptides
Bart De Spiegeleer
Valentijn Vergote
Johan Svenson
Rasmus Karstad
Christian Burvenich
C3
Conference
2009
Concentration-dependent peptide losses during the drying step in the sample preparation: influence of additives
Adel Pezeshki
Valentijn Vergote
Christian Burvenich
Bart De Spiegeleer
C3
Conference
2009
Development of peptide receptor binding assays: methods to avoid false negatives
Valentijn Vergote
Sylvia Van Dorpe
Mathieu Verbeken
Christian Burvenich
Christophe Van De Wiele
William Banks
Bart De Spiegeleer
A1
Journal Article
in
REGULATORY PEPTIDES
2009
Functional genomics of bovine neutrophil during lactation
Mieke Stevens
Adel Pezeshki
Bart De Spiegeleer
Luc Peelman
Christian Burvenich
C3
Conference
2009
Functional quality of new peptide drugs: receptor-binding and tissue-interactions
Mathieu Verbeken
Valentijn Vergote
Christian Burvenich
Christophe Van De Wiele
Andras Ronai
Klara Gyires
Walter Luyten
Bart De Spiegeleer
C3
Conference
2009
Gene expression of TLR4 and associated genes in bovine neutrophils during early and mid lactation
Mieke Stevens
Mario Van Poucke
Luc Duchateau
Luc Peelman
Adel Pezeshki
Bart De Spiegeleer
Christian Burvenich
C3
Conference
2009
Innate defense of bovine teat canal in nonlactating Holstein cows
Adel Pezeshki
Mieke Stevens
Anthony Capuco
Annarita Bruno
Luc Peelman
Bart De Spiegeleer
Christian Burvenich
C3
Conference
2009
Peptidomics of bovine mammary gland: Concentration-dependent peptide losses during sample preparation can be minimized applying n-nonyl-β-D-glucopyranoside
Adel Pezeshki
Valentijn Vergote
Christian Burvenich
Bart De Spiegeleer
C3
Conference
2009
Prepartum immune status and mammary gland involution in cows with modified dry period lengths
Adel Pezeshki
Anthony V. Capuco
Robert J. Collier
Bart De Spiegeleer
Christian Burvenich
C3
Conference
2009
Qbd analytical development of calcitonin bioadhesive formulation
Kevin Geenens
NELE CLOTTENS
Valentijn Vergote
Delphine Coucke
Els Mehuys
Bart De Spiegeleer
C3
Conference
2009
Quality specifications for peptide drugs: a regulatory-pharmaceutical approach
Valentijn Vergote
Christian Burvenich
Christophe Van De Wiele
Bart De Spiegeleer
A1
Journal Article
in
Journal of Peptide Science
2009
The paradox of scored tablets: a cost-saving risk
Bart De Spiegeleer
Lindsay Van Hoorebeke
Anton De Spiegeleer
Pieter Castelein
Lucas Van Bortel
A1
Journal Article
in
Pharmazie
2009
Transdermal behaviour of the N-alkylamide spilanthol
Jente Boonen
Eline Halet
Christian Burvenich
Phillip Blondeel
Bart De Spiegeleer
C3
Conference
2009
2008
Bovine mammary gland peptibolomics: Adsorption of peptides at the sample drying step
Adel Pezeshki
Valentijn Vergote
Christian Burvenich
Bart De Spiegeleer
C1
Conference
2008
Development of quality specifications for peptide drugs
Bart De Spiegeleer
Valentijn Vergote
Christian Burvenich
C3
Conference
2008
Development of system suitability tests for in vitro skin integrity control: impedance and capacitance.
Bart De Spiegeleer
Bram Baert
Valentijn Vergote
Sylvia Van Dorpe
C1
Conference
2008
Growth factor/peptide receptor imaging for the development of targeted therapy in oncology
Christophe Van De Wiele
H Boersma
Rudi Dierckx
Philippus Elsinga
Bart De Spiegeleer
A Van Waarde
A1
Journal Article
in
CURRENT PHARMACEUTICAL DESIGN
2008
HPLC analysis and stress stability of peptide drugs.
Valentijn Vergote
Bram Baert
Bart De Spiegeleer
C1
Conference
2008
Impurity profiling quality control testing of synthetic peptides using liquid chromatography-photodiode array-fluorescence and liquid chromatography-electrospray ionization-mass spectrometry: the obestatin case
Bart De Spiegeleer
Valentijn Vergote
Adel Pezeshki
Kathelijne Peremans
Christian Burvenich
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2008
In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products
Valentijn Vergote
Sylvia Van Dorpe
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2008
Inhibiting protease-activity in peptidomics: strategies during sampling and receptor studies
Valentijn Vergote
Adel Pezeshki
Sylvia Van Dorpe
Christian Burvenich
Bart De Spiegeleer
C1
Conference
2008
LC-UV/MS characterization and DOE optimization of the iodinated peptide obestatin
Valentijn Vergote
Bram Baert
Eva Vandermeulen
Kathelijne Peremans
Henri van Bree
Guido Slegers
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2008
Nuclear medicine and large animal studies in the pharmacological development of psychotropics
Kathelijne Peremans
Bart De Spiegeleer
Kurt Audenaert
Editorial material
2008
Pharmaceutical drugability of peptides
Bart De Spiegeleer
Valentijn Vergote
Sylvia Van Dorpe
Bram Baert
Kurt Audenaert
Christophe Van De Wiele
Kathelijne Peremans
Christian Burvenich
C3
Conference
2008
Quality assessment of pharmacy and internet obtained topical testosterone formulations.
Bram Baert
Valentijn Vergote
Bart De Spiegeleer
C1
Conference
2008
Screening methodology for chemical and metabolic stability of potential peptide drugs
Bart De Spiegeleer
Valentijn Vergote
Adel Pezeshki
Sylvia Van Dorpe
Bram Baert
Christian Burvenich
C1
Conference
2008
Solvent effects on the transdermal penetration of the OECD model compound caffeine.
Bram Baert
Jente Boonen
Jo Lambert
Christian Burvenich
Kathelijne Peremans
Bart De Spiegeleer
C1
Conference
2008
The effect of dry period length reduction to 28 days on the performance of multiparous dairy cows in the subsequent lactation
Adel Pezeshki
Jalil Mehrzad
Gholam Reza Ghorbani
Bart De Spiegeleer
Robert Collier
Christian Burvenich
A1
Journal Article
in
Canadian Journal of Animal Science
2008
The use of [I-123]-2-iodo-L-phenylalanine as an early radiotherapy evaluation tool: In vitro R1M rabdomyosarcoma cell and in vivo mouse experiments
Veerle Kersemans
Valentijn Vergote
Virginie de Gelder
Indira Madani
Hubert Thierens
Wilfried De Neve
J MERTENS
Guido Slegers
Christian Burvenich
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
2008
2007
Adsorption of the model drug testosterone on laboratory tips
Samuel Bodé
Bram Baert
Bart De Spiegeleer
C1
Conference
2007
Analysis of iodinated peptides by LC-DAD/ESI ion trap mass spectrometry
Valentijn Vergote
Samuel Bodé
Kathelijne Peremans
Henri van Bree
Bram Baert
Guido Slegers
Christian Burvenich
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2007
Assessment of the solid-state composition of an active salicylanilide compound by FT-Raman spectroscopy
Bart De Spiegeleer
Bram Baert
N DIERICX
D SEGHERS
Francis Verpoort
Lieven Van Vooren
Christian Burvenich
Guido Slegers
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2007
Bovine blood neutrophil acyloxyacyl hydrolase (AOAH) activity during endotoxin and coliform mastitis
J MEHRZAD
H DOSOGNE
Bart De Spiegeleer
Luc Duchateau
Christian Burvenich
A1
Journal Article
in
VETERINARY RESEARCH
2007
Comparison of the wetting properties of three commonly used simulated intestinal fluids used as dissolution media in the characterization of drugs
Bart De Spiegeleer
Bram Baert
Elien Vangheluwe
Ilse Becue
Jan De Smet
Pieter Spanoghe
Christophe Wille
Paul Van Der Meeren
Guido Slegers
A1
Journal Article
in
JOURNAL OF SOLUTION CHEMISTRY
2007
Imaging of the serotonin-2A receptor before and after pipamperone administration in the canine brain
Kurt Audenaert
Bart De Spiegeleer
E BUNTINX
Valentijn Vergote
Eva Vandermeulen
Simon Vermeire
André Dobbeleir
Filip De Vos
Kathelijne Peremans
C3
Conference
2007
Peptibolomics of the cows' udder: peptide profiling of the teat canal
Lukas Senepart
Valentijn Vergote
Adel Pezeshki
Samuel Bodé
Steve Lefever
Bram Baert
Kathelijne Peremans
Christian Burvenich
Bart De Spiegeleer
C1
Conference
2007
Stability of the OECD model compound benzoic acid in receptor fluids of Franz diffusion cells
Samuel Bodé
Bram Baert
M VANGELE
Jo Lambert
Christian Burvenich
Guido Slegers
Bart De Spiegeleer
A1
Journal Article
in
PHARMAZIE
2007
The effect of pipamperone on the binding index of 123I-5I-R91150, a selective 5-HT2A receptor radioligand, in the canine brain
Kathelijne Peremans
Bart De Spiegeleer
Valentijn Vergote
Eva Vandermeulen
Simon Vermeire
André Dobbeleir
E BUNTINX
Filip De Vos
Kurt Audenaert
C3
Conference
2007
The effect of pipamperone on the binding index of 123I-5I-R91150, a selective 5-HT2A receptor radioligand,in the canine brain
Kathelijne Peremans
Bart De Spiegeleer
Valentijn Vergote
Eva Vandermeulen
Simon Vermeire
André Dobbeleir
E BUNTINX
Filip De Vos
Kurt Audenaert
C3
Conference
2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds
Bram Baert
E DECONINCK
Mireille Van Gele
Marian Slodicka
P STOPPIE
Samuel Bodé
Guido Slegers
Y VANDER HEYDEN
Jo Lambert
J BEETENS
Bart De Spiegeleer
A1
Journal Article
in
BIOORGANIC & MEDICINAL CHEMISTRY
2007
Use of [I-121]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma
Kathelijne Peremans
Veerle Kersemans
Tiziana Liuti
Eva Vandermeulen
Bart Cornelissen
Ingrid Gielen
Bart De Spiegeleer
J MERTENS
Christian Burvenich
Guido Slegers
A1
Journal Article
in
VETERINARY RADIOLOGY & ULTRASOUND
2007
Variation in gene expression of the TLR4 pathway in unstimulated circulating bovine neutrophils during early and mid lactation
Steve Lefever
A DE KETELAERE
Luc Duchateau
G VERMEULEN
Lukas Senepart
Bart De Spiegeleer
Luc Peelman
Christian Burvenich
C1
Conference
2007
2006
Analytical characterisation of arsenic anticoccidials and their determination in poultry feed
Bram Baert
Bart De Spiegeleer
Samuel Bodé
Guido Slegers
Sofie Langendries
Liesbet Poppe
C1
Conference
2006
Characterisation of a preservative system in an oily preparation
Bart De Spiegeleer
E WATTYN
Guido Slegers
P VEYS
G DERRIEU
Lieven Van Vooren
A1
Journal Article
in
PHARMAZIE
2006
Comparative biodistribution study of the new tumor tracer [I-123]-2-iodo-L-phenylalanine with [I-123]-2-iodo-L-tyrosine
Veerle Kersemans
Bart Cornelissen
K KERSEMANS
Rudi Dierckx
Bart De Spiegeleer
J MERTENS
Guido Slegers
A1
Journal Article
in
NUCLEAR MEDICINE AND BIOLOGY
2006
Development of a dissolution method for a meloxicam oral suspension using solubility and IVIVC data
D SEGHERS
Lieven Van Vooren
Bart De Spiegeleer
C1
Conference
2006
I-123/125-labelled 2-iodo-L-phenylalanine and 2-iodo-D-phenylalanine: comparative uptake in various tumour types and biodistribution in mice
Veerle Kersemans
Bart Cornelissen
K KERSEMANS
M BAUWENS
Rudi Dierckx
Bart De Spiegeleer
J MERTENS
Guido Slegers
A1
Journal Article
in
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2006
Influence of sedation and data acquisition method on tracer uptake in animal models: [I-123]-2-iodo-L-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice
Veerle Kersemans
Bart De Spiegeleer
J MERTENS
Guido Slegers
A1
Journal Article
in
NUCLEAR MEDICINE AND BIOLOGY
2006
Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging.
Veerle Kersemans
K KERSEMANS
Bart Cornelissen
Ludovicus Staelens
Bart De Spiegeleer
J MERTENS
Guido Slegers
A1
Journal Article
in
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
2006
RADIOSTABILITY OF VANCOMYCIN
Samuel Bodé
Elien Vangheluwe
Bram Baert
N VAN HOOF
Luc Van Hoorebeke
Hubert Thierens
Jean Paul Remon
Hubert De Brabander
Bart De Spiegeleer
C1
Conference
2006
Stoichiometry of complexes by quantifying qualitative UV-VIS spectroscopic shifts
Bram Baert
Bart De Spiegeleer
Guido Slegers
Celine Lagae
C1
Conference
2006
Synthesis and HPLC-purification of [Br-77]TMC125-R165335 (etravirine), a new anti-HIV drug of the DAPY-NNRTI class
Bart De Spiegeleer
Filip Dumont
Kathelijne Peremans
Christian Burvenich
Lieven Van Vooren
J ROSIER
L BAERT
P WIGERINCK
Guido Slegers
A1
Journal Article
in
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
2006
The importance of the cosolvent propylene glycol on the antimicrobial preservative efficacy of a pharmaceutical formulation by DOE-ruggedness testing
Bart De Spiegeleer
E WATTYN
Guido Slegers
Paul Van Der Meeren
K VLAMINCK
Lieven Van Vooren
A1
Journal Article
in
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
2006
2005
Determination of the relative amounts of three crystal forms of a benzimidazole drug in complex finished formulations by FT-Raman spectroscopy
Bart De Spiegeleer
D SEGHERS
R WIEME
J SCHAUBROECK
Francis Verpoort
Guido Slegers
Lieven Van Vooren
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2005
Evaluation of the stability of chlortetracycline in granular premixes by monitoring its conversion into degradation products
J DIANA
L VANDENBOSCH
Bart De Spiegeleer
J HOOGMARTENS
E ADAMS
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2005
In vivo evaluation and dosimetry of I-123-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT in an R1M rhabdomyrosarcoma athymic mouse model
Veerle Kersemans
Bart Cornelissen
Klaus Bacher
K KERSEMANS
Hubert Thierens
Rudi Dierckx
Bart De Spiegeleer
Guido Slegers
J MERTENS
A1
Journal Article
in
JOURNAL OF NUCLEAR MEDICINE
2005
Mass uniformity: Influence of operational compression conditions on breakability of scored tablets as part of manufacturing robustness evaluation
Bart De Spiegeleer
Lieven Van Vooren
T THONISSEN
Philippe Joye
Bart Cornelissen
G LAMMENS
Guido Slegers
A1
Journal Article
in
JOURNAL OF FOOD AND DRUG ANALYSIS
2005
2003
Anti-microbial preservatives in oily preparations
Bart De Spiegeleer
P Van Nimmen
G Lammens
Guido Slegers
I Huyghe
A2
Journal Article
in
PHARMEUROPA
2003
Distribution study of three-phase emulsions using confocal laser scanning microscopy (CLSM)
Bart De Spiegeleer
Jan Cocquyt
Patric Van Oostveldt
Paul Van Der Meeren
Lieven Van Vooren
C1
Conference
2003
Investigation of preservative systems by experimental design: drug product optimisation and robustness characterisation
Bart De Spiegeleer
Lieven Van Vooren
Elke Wattijn
Guido Slegers
W VAN DEN BOSSCHE
Paul Van Der Meeren
P VEYS
K VLAMINCK
H NUYTTEN
P MUSSCHE
C1
Conference
2003
Physical stability of diluted suspo-emulsions
Bart De Spiegeleer
Lieven Van Vooren
Z POLADI
Jan Cocquyt
Paul Van Der Meeren
C1
Conference
2003
Physico-chemical screening tests using IV2SOL technology in the development of liquid pharmaceutical formulations
Bart De Spiegeleer
E WATTYN
Guido Slegers
W VAN DEN BOSSCHE
H DOSOGNE
C1
Conference
2003
Raman spectroscopy in the polymorphic characterisation of drugs
Bart De Spiegeleer
N DIERICX
Francis Verpoort
P VEYS
K VLAMINCK
Lieven Van Vooren
C3
Conference
2003
2002
Statistical analysis of tablet breakability methods
Lieven Van Vooren
Bart De Spiegeleer
T Thonissen
Philippe Joye
J Van Durme
Guido Slegers
A1
Journal Article
in
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
2002
2001
A novel bending point criterion for dissolution profile interpretation
L Van Vooren
G Krikilion
J Rosier
Bart De Spiegeleer
A1
Journal Article
in
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
2001
Dissolution stability and IVIVC investigation of a buccal tablet
Bart De Spiegeleer
L Van Vooren
J Voorspoels
D Thone
J Rosier
A1
Journal Article
in
ANALYTICA CHIMICA ACTA
2001
Evaluation of dissolution profiles using principal component analysis
E Adams
R De Maesschalck
Bart De Spiegeleer
Y Vander Heyden
J Smeyers-Verbeke
DL Massart
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2001
1996
Half-fraction and full factorial designs versus central composite design for retention modelling in reversed-phase ion-pair liquid chromatography
Jacques O De Beer
Catherine V Vandenbroucke
Désiré L Massart
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
1996
1992
Relationship between content limits and assay methods : an interlaboratory statistical evaluation
Jacques O De Beer
Bart De Spiegeleer
Jos Hoogmartens
Isabelle Samson
Desiré L Massart
Martine Moors
A1
Journal Article
in
ANALYST
1992
1991
High-performance thin-layer chromatographic analysis of thiazine dyes on silica, cyano, and reversed-phase C18 layers
BM Van Liedekerke
Andreas De Leenheer
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHIC SCIENCE
1991
1990
Planar chromatography : most flexible analytic technique in the pharmaceutical industry
A Paradis
Bart De Spiegeleer
A1
Journal Article
in
ANALUSIS
1990
The tissue distribution in rats of [PT-195M]carboplatin following intravenous, intraperitoneal and oral administration
N Tinker
Bart De Spiegeleer
H Sharma
H Jackson
C McAuliffe
JP Reman
A1
Journal Article
in
NUCLEAR MEDICINE AND BIOLOGY
1990
1989
A rapid high-performance thin-layer chromatographic screening method for sulfonamides residues in animal muscle tissues
L Van Poucke
D Rousseau
Bart De Spiegeleer
Carlos Van Peteghem
P1
Conference
1989
High performance liquid chromatography stability study of malonyl-coenzyme A, using statistical experimental designs
Bart De Spiegeleer
Karel Sintobiin
Jan Desmet
A1
Journal Article
in
BIOMEDICAL CHROMATOGRAPHY
1989
Planar chromatography of Echinacea species extracts with automated multiple development
Marc FM Trypsteen
Robert GE Van Severen
Bart De Spiegeleer
A1
Journal Article
in
ANALYST
1989
Structural characterization of cisplatin analogues by fast atom bombardment (FAB) and laser microprobe mass spectrometry (LAMMA)
J Claereboudt
Bart De Spiegeleer
EA De Bruijn
R Gijbels
M Claeys
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
1989
Synthese en analyse van N-13-cisplatin, (ethyleendiamine)(1-C-11-malonaat)platinum(II) en Pt-195m-carboplatin
Bart De Spiegeleer
Dissertation
1989
1988
High-performance liquid chromatography of α-substituted acetic acid derivatives
Bart De Spiegeleer
Guido Slegers
W Van Den Bossche
A Claeys
P De Moerloose
A1
Journal Article
in
JOURNAL OF LIQUID CHROMATOGRAPHY
1988
Synthesis and radiopharmaceutical preparation of (ethylenediamine) (1-carbon-11-malonate) platinum(II) for PET studies
Bart De Spiegeleer
Patrick Goethals
Guido Slegers
Eric Gillis
Walter Van den Bossche
Prosper De Moerloose
A1
Journal Article
in
JOURNAL OF NUCLEAR MEDICINE
1988
1987
A strategy for two-dimensional, high-performance thin-layer chromatography, applied to local anesthetics
Bart De Spiegeleer
W Van Den Bossche
P De Moerloose
D Massart
A1
Journal Article
in
CHROMATOGRAPHIA
1987
Criterion for evaluation and optimization in thin-layer chromatography
Bart De Spiegeleer
Prosper De Moerloose
Guido Slegers
A1
Journal Article
in
ANALYTICAL CHEMISTRY
1987
Intellectual flexibility
Bart De Spiegeleer
A1
Journal Article
in
CHEMICAL & ENGINEERING NEWS
1987
1986
Direct assay for phosphotransacetylase and acetyl-coenzyme a carboxylase by high-performance liquid chromatography
Bart De Spiegeleer
Geert Mannens
Guido Slegers
Walter Van den Bossche
Albert Claeys
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
1986
Microscale synthesis of nitrogen-13-labeled cisplatin
Bart De Spiegeleer
Guido Slegers
Carlos Vandecasteele
Walter Van den Bossche
Karel Schelstraete
Albert Claeys
Prosper De Moerloose
A1
Journal Article
in
JOURNAL OF NUCLEAR MEDICINE
1986
Rapid determination of malonic acid by ion-pair reversed-phase high-performance liquid chromatography
Bart De Spiegeleer
Guido Slegers
W Van Den Bossche
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
1986
1985
Determination of methyl nicotinate in pharmaceutical creams by high-performance thin-layer chromatography
Bart De Spiegeleer
W Van Den Bossche
P De Moerloose
H Stevens
A1
Journal Article
in
CHROMATOGRAPHIA
1985
1984
Quantitative analysis of cis-dichlorodiammineplatinum(II) by high-performance thin-layer chromatography
Bart De Spiegeleer
Guido Slegers
W Van Den Bossche
P De Moerloose
A1
Journal Article
in
JOURNAL OF CHROMATOGRAPHY
1984
