Research Explorer

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Researcher

Barbara Gilbert

Publications & Research Data

Awards & Distinctions

25 Results

2025

ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death

Dario PriemJon HuygheBarbara GilbertSimon VerdonckTom DelangheBruno VerstraetenEsther HostePeter VandenabeeleJonathan MaelfaitGeert van Loo et al.

A1 Journal Article in IMMUNITY

2022

ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.

Jon HuygheDario PriemLisette Van HoveBarbara GilbertJ FritschY UchiyamaEsther HosteGeert van LooMathieu Bertrand

A1 Journal Article in SCIENCE

Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding

Steven TimmermansNicolette J.D. VerhoogKelly Van LooverenSylviane DewaeleTino HochepiedMelanie EggermontBarbara GilbertAnne Boerema-de MunckTineke VanderhaeghenJoke Vanden Berghe et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2021

Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor

Tom DelangheJon HuygheSeungheon LeeDario PriemSamya Van CoillieBarbara GilbertSze Men ChoiPeter VandenabeeleAlexei DegterevGregory D. Cuny et al.

A1 Journal Article in CELL DEATH & DISEASE

2020

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

Michael DevosGiel TangheBarbara GilbertEvelien DierickMaud VerheirstraetenJosephine NemegeerRichard de ReuverSylvie LefebvreJolien De MunckJan Rehwinkel et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2019

Keratinocyte expression of A20/TNFAIP3 controls skin inflammation associated with atopic dermatitis and psoriasis

Michael DevosDenis A MogilenkoSébastien FleuryBarbara GilbertCoralie BecquartSandrine QuemenerHélène DehondtPeter TougaardBart StaelsClaus Bachert et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2018

Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation

Corinne UrwylerGiel TangheKirsten LeursBarbara GilbertRiet De RyckeMichiel De BruyneSaskia LippensSona BartunkovaPhilippe De GrooteCarien Niessen et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2017

Elevated ΔNp63α levels facilitate epidermal and biliary oncogenic transformation

Michael DevosBarbara GilbertGeertrui DeneckerKirsten LeursConor Mc GuireKelly LemeireTino HochepiedMarnik VuylstekeJo LambertCaroline Van den Broecke et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2015

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

Philippe De GrooteHong Tran ThiMathias FransenGiel TangheCorinne UrwylerBram De CraeneKirsten LeursBarbara GilbertGriet Van ImschootRiet De Rycke et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2014

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

Bert SchepensKoen SedeynLiesbeth Vande GinsteSarah De BaetsMichael SchotsaertKenny RooseLieselot HouspieMarc Van RanstBarbara GilbertNico van Rooijen et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

Nozomi TakahashiLars VereeckeMathieu BertrandLinde DuprezScott B BergerTatyana DivertAmanda GonçalvesMozes SzeBarbara GilbertStephanie Kourula et al.

A1 Journal Article in NATURE

2013

Caspase-14 overexpression in hairless mice is not involved in utricle formation

Michael DevosPhilippe De GrooteBarbara GilbertInge BruggemanKirsten LeursSaskia LippensPeter VandenabeeleWim Declercq

A1 Journal Article in EXPERIMENTAL DERMATOLOGY

Caspase-14-deficient mice are more prone to the development of parakeratosis

Esther HosteGeertrui DeneckerBarbara GilbertFilip Van NieuwerburghLeslie van der FitsBob AsselberghRiet De RyckeJean-Pierre HachemDieter DeforceErrol P Prens et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2012

Filaggrin degradation by caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis

Michael DevosJanne PrawittDelphine Staumont-SalleEsther HosteSebastién FleuryEmmanuel BouchaertBarbara GilbertSaskia LippensPeter VandenabeeleDavid Dombrowicz et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2011

Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin

Esther HostePatrick KempermanMichael DevosGeertrui DeneckerSanja KezicNico YauBarbara GilbertSaskia LippensPhilippe De GrooteRia Roelandt et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

Mathieu BertrandSaskia LippensAn StaesBarbara GilbertRia RoelandtJelle De MedtsKris GevaertWim DeclercqPeter Vandenabeele

A1 Journal Article in PLOS ONE

Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

Saskia LippensS LefebvreBarbara GilbertMozes SzeMichael DevosKelly VerhelstLars VereeckeConor Mc GuireChris GuerinPeter Vandenabeele et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2007

Caspase-14 protects against epidermal UVB photo-damage and water loss

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensC VAN DEN BROUCKEPetra Van DammeKatharina D'HerdeJ HACHEM et al.

Caspase-14 protects against epidermal UVB photo-damage and water loss.

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensC VAN DEN BROUCKEPetra Van DammeKatharina D'HerdeJ HACHEM et al.

Caspase-14 protects against epidermal UVB photodamage and water loss

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensCaroline Van den broeckePetra Van DammeKatharina D'HerdeJP HACHEM et al.

A1 Journal Article in NATURE CELL BIOLOGY

2006

Role of caspase-14 in terminal differentiation of keratinocytes

Geertrui DeneckerEsther HosteBarbara GilbertTino HochepiedPetra OvaereSaskia LippensCaroline VandenbrouckeKatharina D'HerdePeter VandenabeeleWim Declercq

The secret life of caspase-14

Geertrui DeneckerEsther HosteT HOCHPIEDBarbara GilbertPetra OvaereKatharina D'HerdeCaroline VandenbrouckeSaskia LippensLore SchoonjansClaude Libert et al.

2005

The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program

Bram De CraeneBarbara GilbertChristophe StoveErik BruyneelFrans Van RoyGeert Berx

A1 Journal Article in CANCER RESEARCH

2004

GATA-4 and MEF2C transcription factors control the tissue-specific expression of the αT-catenin gene CTNNA3

Griet VanpouckeSteven GoossensBram De CraeneBarbara GilbertFrans Van RoyGeert Berx

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2003

Defining desmosomal plakophilin-3 interactions

Stefan BonnéBarbara GilbertM HATZFELDX CHENKJ GREENFrans Van Roy

A1 Journal Article in JOURNAL OF CELL BIOLOGY