Research Explorer

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Researcher

Barbara De Moerloose

Publicaties & datasets

Prijzen & Erkenningen

313 Results

2025

Exploring germline variants in genes associated with inborn errors of immunity and inherited bone marrow failure syndromes in pediatric hematological malignancies

Jette J. BakhuizenFreerk van DijkSebastian B.B. BonLars T. van der VekenManon M.H. HuibersJoris M. van MontfransMarieke De BruyneBarbara De MoerlooseFilomeen HaerynckJan L.C. Loeffen et al.

A1 Artikel in een tijdschrift in EUROPEAN JOURNAL OF CANCER

Exploring the pathobiology and therapeutic horizons of pediatric acute myeloid leukemia

Jolien VanhoorenTim LammensBarbara De MoerlooseJan Gettemans

Involvement of THBS1 in myeloid sarcoma of acute myeloid leukemia

Zhiyao RenJolien VanhoorenBarbara De MoerlooseTim Lammens

Redactioneel materiaal

Management of children and adolescents with chronic myeloid leukemia in chronic phase : international pediatric chronic myeloid leukemia expert panel recommendations

Frédéric MillotMirella AmpatzidouNirmalya Roy MoulikSanjay TewariAlaa ElhaddadMahmoud HammadHerbert PichlerThomas LionAthanasios TragiannidisHaruko Shima et al.

A1 Artikel in een tijdschrift in LEUKEMIA

Nidogen-1, a player in KMT2A-rearranged pediatric acute myeloid leukemia

Jolien VanhoorenLarissa DenewethLuca PagliaroZhiyao RenMariateresa GiaimoRafaella ZamponiGiovanni RotiBarbara DepreterMattias HofmansBarbara De Moerloose et al.

A1 Artikel in een tijdschrift in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prime-time for IncRNA signatures in acute myeloid leukaemia?

Z RenBarbara De MoerlooseTim Lammens

A2 Artikel in een tijdschrift in BELGIAN JOURNAL OF HEMATOLOGY

Prime-time for LncRNA signatures in acute myeloid leukemia?

Zhiyao RenBarbara De MoerlooseTim Lammens

A1 Artikel in een tijdschrift in ANNALS OF HEMATOLOGY

Profiling histone post-translational modifications to identify signatures of epigenetic drug response in T-cell acute lymphoblastic leukemia

Laura CorveleynLien ProvezOsman SatilmisNina RefhagenMattias LandforsWouter SleeckxBéatrice LintermansAmélie De MaesschalckRishi S. KotechaBarbara De Moerloose et al.

Project EVOLVE : an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

Sara K. SilbertAlexander W. RankinChloe N. HoangAlexandra SemchenkovaRegina M. MyersElena ZerkalenkovaHao-Wei WangAlexandra E. KovachConstance M. YuanDana Delgado Colon et al.

A1 Artikel in een tijdschrift in BLOOD

The role of UBTF-TD mutations in paediatric acute myeloid leukaemia and myelodysplastic syndrome

B DecuyperI AndriessenMattias HofmansBarbara De Moerloose

2024

A 69 long non-coding RNAs expression signature predicts relapse and acts as an independent prognostic factor in pediatric acute myeloid leukemia

Zhiyao RenJolien VanhoorenCharlotte DerpoorterBarbara De MoerlooseTim Lammens

A 69 long noncoding RNA signature predicts relapse and acts as independent prognostic factor in pediatric AML

Zhiyao RenJolien VanhoorenCharlotte DerpoorterBarbara De MoerlooseTim Lammens

A1 Artikel in een tijdschrift in BLOOD ADVANCES

Characterization of pediatric acute myeloid leukemia with t(7;12)(q36;p13)

Anders ÖstlundAhmed WarakyAnna StaffasHelene SjögrenBarbara De MoerlooseNira Arad‐CohenDaniel CheukJose Maria Fernandez NavarroKirsi JahnukainenGertjan J. L. Kaspers et al.

A1 Artikel in een tijdschrift in GENES CHROMOSOMES & CANCER

Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis : results from the NOPHO-DBH AML 2012 protocol

Bernward ZellerNira Arad-CohenDaniel CheukBarbara De MoerlooseJose M Fernandez NavarroHenrik HasleKirsi JahnukainenKristian Lovvik Juul-DamGertjan KaspersZanna Kovalova et al.

A1 Artikel in een tijdschrift in HAEMATOLOGICA

Mitoxantrone versus liposomal daunorubicin in induction of pediatric AML with risk stratification based on flow cytometry measurement of residual disease

Anne TierensNira Arad-CohenDaniel CheukBarbara De MoerlooseJose Maria Fernandez NavarroHenrik HasleKirsi JahnukainenKristian Løvvik Juul-DamGertjan KaspersZanna Kovalova et al.

A1 Artikel in een tijdschrift in JOURNAL OF CLINICAL ONCOLOGY

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia

André Pedro Pinto De AlmeidaSara T'SasLuca PagliaroIgor FijalkowskiWouter SleeckxHannah Van SteenbergeRaffaella ZamponiBéatrice LintermansWouter Van LoockeBruno Palhais et al.

A1 Artikel in een tijdschrift in HEMASPHERE

Nidogen-1, a novel player in KMT2A-rearranged pediatric acute myeloid leukemia patients, expressed in the leukemic stem cell

Jolien VanhoorenLarissa DenewethLuca PagliaroZhiyao RenBarbara DepreterMattias HofmansBarbara De MoerlooseTim Lammens

Precision medicine in relapsed and refractory paediatric haematological malignancies and the role of an international tumour board

Alexandra ReekmansUri IlanJudith M BoerTim LammensSteven GoossensC Michel ZwaanMonique L den BoerBarbara De Moerloose

A2 Artikel in een tijdschrift in BELGIAN JOURNAL OF HEMATOLOGY

Results of the prospective EORTC Children Leukemia Group study 58081 in precursor B‐ and T‐cell acute lymphoblastic leukemia

Carine DomenechMichal KicinskiBarbara De MoerlooseCaroline PietteWadih A. ChahlaLaure KornreichMarlène PasquetAnne UyttebroeckAlexandre TheronMarilyne Poirée et al.

A1 Artikel in een tijdschrift in HEMASPHERE

Spontaneous remission and loss of monosomy 7 : a window of opportunity for young children with SAMD9L syndrome

Miriam ErlacherFelicia AndresenMartina SukovaJan StaryBarbara De MoerlooseJutte van der Werff Ten BoschMichael DworzakMarkus G. SeidelSophia PolychronopoulouRita Beier et al.

A1 Artikel in een tijdschrift in HAEMATOLOGICA

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette Roels et al.

A1 Artikel in een tijdschrift in HAEMATOLOGICA

Ultra-deep sequencing and single cell multi-omics characterize measurable residual disease and identify therapy-survived clone in pediatric acute myeloid leukemia

Borhan R. R SaeedAnastasia SaboliAnna RehammarAdam MolnarErik Delsing MalmbergBarbara DepreterGiti Shah BarkhordarBarbara De MoerlooseTim LammensLars Palmqvist et al.

2023

A 46 long non-coding RNAs expression signature accurately predicts relapse and acts as an independent prognostic factor in pediatric acute myeloid leukemia

Zhiyao RenJolien VanhoorenCharlotte DerpoorterBarbara De MoerlooseTim Lammens

CAR-T in the treatment of acute myeloid leukemia : barriers and how to overcome them

Jolien VanhoorenRani DobbelaereCharlotte DerpoorterLarissa DenewethLaurens Van CampAnne UyttebroeckBarbara De MoerlooseTim Lammens

A1 Artikel in een tijdschrift in HEMASPHERE

Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia

Lene KarlssonDaniel CheukBarbara De MoerlooseHenrik HasleKirsi JahnukainenKristian Løvvik Juul‐DamGertjan KaspersZanna KovalovaBirgitte LausenUlrika Norén Nyström et al.

A1 Artikel in een tijdschrift in BRITISH JOURNAL OF HAEMATOLOGY

Drug response profiling informs personalized bridging to cell therapy for patients with relapsed/refractory acute lymphoblastic leukemia

Fabio D. SteffenAndrej LissatJulia AltenCornelia EckertBodmer NicoleThorhauge Als-Nielsen Bodil E.Adriana BalduzziSarah ElitzurAndras KristonGergely Nyiri et al.

In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia

Maaike Van TrimpontAmanda M. SchalkYanti De VisserHien Anh NguyenLindy ReunesKatrien VandemeulebroeckeEvelien PeetersYing SuHyun LeePhilip L. Lorenzi et al.

A1 Artikel in een tijdschrift in HAEMATOLOGICA

Management of children and adolescents with chronic myeloid leukemia in blast phase : international pediatric CML expert panel recommendations

Stephanie SembillMaria AmpatzidouSonali ChaudhuryMichael DworzakKrzysztof KalwakAxel KarowAlexander KianiManuela KrumbholzMaaike LuesinkNora Naumann-Bartsch et al.

A1 Artikel in een tijdschrift in LEUKEMIA

Measurable residual disease and fusion partner independently predict survival and relapse risk in childhood KMT2A-rearranged acute myeloid leukemia : a study by the International Berlin-Frankfurt-Münster Study Group

Romy E. van WeelderenKim KleinChristine J. HarrisonYilin JiangJonas AbrahamssonNira Arad-CohenEmmanuelle Bart-DelabesseBarbara BuldiniBarbara De MoerlooseMichael N. Dworzak et al.

A1 Artikel in een tijdschrift in JOURNAL OF CLINICAL ONCOLOGY

Outcome of chimeric antigen receptor T-cell therapy following treatment with inotuzumab ozogamicin in children with relapsed or refractory acute lymphoblastic leukemia

Valeria CeolinErica BrivioHarm van TinterenSusan R. RheingoldAllison LeahyBritta VormoorMaureen M. O’BrienJeremy D. RubinsteinKrzysztof KalwakBarbara De Moerloose et al.

A1 Artikel in een tijdschrift in LEUKEMIA

Outcomes of childhood noninfant acute lymphoblastic leukemia with 11q23/KMT2A rearrangements in a modern therapy era : a retrospective international study

Andishe AttarbaschiAnja MörickeChristine J. HarrisonGeorg MannAndré BaruchelBarbara De MoerlooseValentino ConterMeenakshi DevidasSarah ElitzurGabriele Escherich et al.

A1 Artikel in een tijdschrift in JOURNAL OF CLINICAL ONCOLOGY

Retrospective study of children with chronic myeloid leukemia treated in Belgium between 2000 and 2021

Klaartje Van SchelvergemLaurens Van CampVeerle LabarqueLaure KornreichKoen NorgaBarbara De Moerloose

The clinical spectrum and biological findings in RAS-associated juvenile myelomonocytic leukemia and RAS-associated autoimmune leukoproliferative disorder

Hanne VerhulstLaurens Van CampMattias HofmansBarbara De Moerloose

The prognostic value of IKZF1(plus) in B‐cell progenitor acute lymphoblastic leukemia : results from the EORTC 58951 trial

Michal KicinskiChloé ArfeuilleNathalie GrardelMarleen BakkusAurélie Caye‐EudeGeneviève PlatAlina FersterAnne UyttebroeckBarbara De MoerloosePierre Rohrlich et al.

A1 Artikel in een tijdschrift in PEDIATRIC BLOOD & CANCER

2022

Brachytherapy for pediatric patients at Gustave Roussy Cancer Campus : a model of international cooperation for highly specialized treatments

Cyrus ChargariChristine Haie-MederSophie EspenelMax-Adrien GarciaMyriam Ben-ArushStéphanie BolleAnna BorjessonMaja CesenRita Costa LagoAnne-Sophie Defachelles et al.

A1 Artikel in een tijdschrift in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Clinical outcomes of second relapsed and refractory first relapsed paediatric AML : a retrospective study within the NOPHO‐DB SHIP consortium

Tara WhiteGertjan KaspersJonas AbrahamssonNira Arad‐CohenDaniela CianciJose FernandezShau‐Yin HaHenrik HasleBarbara De MoerlooseC. Michel Zwaan et al.

A1 Artikel in een tijdschrift in BRITISH JOURNAL OF HAEMATOLOGY

Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Laurens Van CampJolien VanhoorenBarbara DepreterMartijn de JongAnne UyttebroeckAn Van DammeLaurence DedekenMarie-Françoise DresseJutte van der Werff ten BoschMattias Hofmans et al.

Deciphering the non-coding landscape of pediatric acute myeloid leukemia

Jolien VanhoorenLaurens Van CampBarbara DepreterMartijn de JongAnne UyttebroeckAn Van DammeLaurence DedekenMarie-Françoise DresseJutte van der Werff ten BoschMattias Hofmans et al.

Deciphering the non-coding RNA landscape of pediatric acute myeloid leukemia

Jolien VanhoorenLaurens Van CampBarbara DepreterMartijn de JongAnne UyttebroeckAn Van Van DammeLaurence DedekenMarie-Françoise DresseJutte van der Werff ten BoschMattias Hofmans et al.

A1 Artikel in een tijdschrift in CANCERS

Familial hemophagocytic lymphohistiocytosis type 3 presenting as neonatal cholestasis and splenomegaly

Delfien BogaertRuth De BruyneArnaud VanlanderLara GarabedianYves LouisFilomeen HaerynckVictoria BordonBarbara De Moerloose

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Guideline for management of non-Down syndrome neonates with a myeloproliferative disease on behalf of the I-BMF AML Study Group and EWOG-MDS

E BertrumsCM ZwaanD HasegawaV de HaasDN ReinhardtF LocatelliBarbara De MoerlooseM DworzakA BuijsP Smisek et al.

A1 Journal Article in HAEMATOLOGICA

Immunoglobulin heavy chain high-throughput sequencing in pediatric B-precursor acute lymphoblastic leukemia : is the clonality of the disease at diagnosis related to its prognosis?

Gabriel LevyMichal KicinskiJona Van der StraetenAnne UyttebroeckAlina FersterBarbara De MoerlooseMarie-Francoise DresseChristophe ChantrainBénédicte BrichardMarleen Bakkus

A1 Journal Article in FRONTIERS IN PEDIATRICS

Mutational permutations of a single amino acid exert divergent phenotypic effects in human, mice and cellular models of SAMD9L bone marrow failure disorder

Sushree S SahooCharnise Goodings-HarrisShondra MillerMaria Angeles Lillo OsunaBaranda S HansenLei HanTi-Cheng ChangTim LammensMattias HofmansMarta Derecka et al.

Novel insights on the use of L-asparaginase as an efficient and safe anti-cancer therapy

Maaike Van TrimpontEvelien PeetersYanti De VisserAmanda M. SchalkVeerle MondelaersBarbara De MoerlooseArnon LavieTim LammensSteven GoossensPieter Van Vlierberghe

A1 Journal Article in CANCERS

Optimization of asparaginase therapy in childhood acute lymphoblastic leukemia

Veerle MondelaersBarbara De MoerlooseTim Lammens

Practice guidelines for the therapeutic drug monitoring of asparaginase in acute lymphoblastic leukemia

Veerle MondelaersTim LammensMartijn de JongLarissa DenewethKatrien VandemeulebroeckeBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Supportive care in pediatric acute myeloid leukemia : expert-based recommendations of the NOPHO-DB-SHIP consortium

Nira Arad-CohenBernward ZellerJonas AbrahamssonJose Maria Fernandez NavarroDaniel CheukSauli PalmuVitor CostaBarbara De MoerlooseHenrik HasleKirsi Jahnukainen et al.

A1 Journal Article in EXPERT REVIEW OF ANTICANCER THERAPY

Targeted therapy in juvenile myelomonocytic leukemia : where are we now?

Nele De VosMattias HofmansTim LammensBram De WildeNadine Van RoyBarbara De Moerloose

A1 Journal Article in PEDIATRIC BLOOD & CANCER

TEARDRoP Oncology : BBRMI.be workshop on sustainability

Liselot MusBram De WildeCatherine Van Der StraetenBarbara De MoerlooseSandra JacobsSylvie RotteyMarie-Francoise DresseIlse De Reze

TEARDRoP oncology : good practices for paediatric biobanking

Liselot MusBram De WildeCatherine Van Der StraetenBarbara De MoerlooseSandra JacobsSylvie RotteyMarie-Francoise DresseIlse De Reze

The TEARDRoP (Team early drug development in Paediatric oncology) consortium : to help Research find its way to improved treatments for children with cancer

Liselot MusBram De WildeCatherine Van Der StraetenBarbara De MoerlooseSandra JacobsSylvie RotteyMarie-Francoise DresseIlse De Reze

Three-year update of tisagenlecleucel in pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia in the ELIANA trial

Theodore W. LaetschShannon L. MaudeSusana RivesHidefumi HiramatsuHenrique BittencourtPeter BaderAndré BaruchelMichael BoyerBarbara De MoerlooseMuna Qayed et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Tisagenlecleucel therapy for relapsed or refractory B-cell acute lymphoblastic leukaemia in infants and children younger than 3 years of age at screening : an international, multicentre, retrospective cohort study

Sara GhorashianElad JacobyBarbara De MoerlooseSusana RivesDenise BonneyGeoff ShentonPeter BaderNicole BodmerAgueda Molinos QuintanaBlanca Herrero et al.

A1 Journal Article in LANCET HAEMATOLOGY

2021

CAR-T treatment of pediatric AML : a long and winding road

Barbara De Moerloose

Editorial material

CircRNAs dysregulated in juvenile myelomonocytic leukemia : CircMCTP1 stands out

Anna Dal MolinMattias HofmansEnrico GaffoAlessia BuratinHélène CavéChristian FlothoValerie de HaasCharlotte M. NiemeyerJan StaryPieter Van Vlierberghe et al.

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

Sushree S. SahooVictor B. PastorCharnise GoodingsRebecca K. VossEmilia J. KozyraAmina SzvetnikPeter NoellkeMichael DworzakJan StaryFranco Locatelli et al.

A1 Journal Article in NATURE MEDICINE

CNS-3 status remains an independent adverse prognosis factor in children with acute lymphoblastic leukemia (ALL) treated without cranial irradiation : results of EORTC Children Leukemia Group study 58951

N. SirventS. SuciuBarbara De MoerlooseA. FersterF. MazingueG. PlatK. YakoubenA. UyttebroeckC. PaillardV Costa et al.

A1 Journal Article in ARCHIVES DE PEDIATRIE

Current developments and hurdles in CAR-T cell therapy for acute myeloid leukaemia

Laurens Van CampTim LammensAnne UyttebroeckBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeEva TerrasBarbara DenysLaurence DedekenMarie-Francoise DresseJutte Van der Werff Ten Bosch et al.

A1 Journal Article in PEDIATRIC RESEARCH

Features and outcome of chronic myeloid leukemia at very young age : data from the International Pediatric Chronic Myeloid Leukemia Registry

Adalet Meral GunesFrederic MillotKrzysztof KalwakBirgitte LausenPetr SedlacekA. Birgitta VersluysMichael DworzakBarbara De MoerlooseMeinolf Suttorp

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Germline SAMD9L triple-allelic mosaicism with independent segregation into biallelic offsprings : molecular support for non-mendelian inheritance

S SahooC GoodingsM Angeles LilloTim LammensJ van der Werff ten BoschB StrahmBarbara De MoerlooseM Wlodarski

Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome

Rachel BortnickMarcin WlodarskiValerie de HaasBarbara De MoerlooseMichael DworzakHenrik HasleRiccardo MasettiJan StarýDominik TurkiewiczMarek Ussowicz et al.

A1 Journal Article in BONE MARROW TRANSPLANTATION

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensBarbara DepreterYing WuMiriam ErlacherAurélie CayeHélène CavéChristian FlothoValerie de HaasCharlotte M. Niemeyer et al.

A1 Journal Article in SCIENTIFIC REPORTS

Novel therapeutic targets in juvenile myelomonocytic leukaemia : are noncoding RNAs valuable treatment options?

Mattias HofmansTim LammensJan PhilippéBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Novel therapeutic targets in juvenile myelomonocytic leukemia : are noncoding RNAs valuable treatment options?

Mattias HofmansBarbara De MoerlooseJan PhilippéTim Lammens

Parental experience and emotional well-being in families with a child with a chronic disease during the COVID 19 pandemic

Eline Van HoeckeKarlien DhondtAnn RaesStephanie Van BiervlietBarbara De MoerlooseSara Van AkenFilomeen HaerynckLevi HosteHelene VerhelstBart Soenens et al.

Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia

John E LevineStephan A GruppMichael A PulsipherAndrew C DietzSusana RivesG Douglas MyersKeith J AugustMichael R VernerisJochen BuechnerTheodore W Laetsch et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

Practical guidelines for monitoring and management of coagulopathy following tisagenlecleucel CAR T-cell therapy

Jochen BuechnerStephan A. GruppHidefumi HiramatsuDavid T. TeacheySusana RivesTheodore W. LaetschGregory A. YanikPatricia WoodRakesh AwasthiLan Yi et al.

A1 Journal Article in BLOOD ADVANCES

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

Filip MatthijssensNitesh D. SharmaMonique NysusChristian K. NicklHuining KangDominique R. PerezBéatrice LintermansWouter Van LoockeJuliette RoelsSofie Peirs et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

TARP as antigen in cancer immunotherapy

Jolien VanhoorenCharlotte DerpoorterBarbara DepreterLarissa DenewethJan PhilippéBarbara De MoerlooseTim Lammens

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

The variable biological signature of refractory cytopenia of childhood (RCC), a retrospective EWOG-MDS study

Demi T.C. de WinterAnton W. LangerakJeroen te MarveldeMichael N. DworzakBarbara De MoerlooseJan StarýFranco LocatelliHenrik HasleAndrica C.H. de VriesMarkus Schmugge et al.

A1 Journal Article in LEUKEMIA RESEARCH

2020

A semi-mechanistic population pharmacokinetic/pharmacodynamic model of bortezomib in pediatric patients with relapsed/refractory acute lymphoblastic leukemia

Julie M JanssenTPC DorloD NiewerthAJ WilhelmCM ZwaanJH BeijnenA AttarbaschiA BaruchelF FagioliT Klingebiel et al.

A1 Journal Article in CLINICAL PHARMACOKINETICS

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozBronislawa SzarzynskaMattias LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy Reunes et al.

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozB SzarzyńskaM LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy Reunes et al.

A2 Journal Article in BLOOD CANCER DISCOVERY

Big children or small adults? Acute myeloid leukaemia (AML) treatment in adolescence and young adulthood

Karolien MaesBarbara De MoerlooseMARIJKE QUAGHEBEURJOHAN DE MUNTERTessa KerreIne Moors

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Big children or small adults? Leukaemia treatment in adolescence and young adulthood

Rutger CallensBarbara De MoerlooseTessa KerreMARIJKE QUAGHEBEURJOHAN DE MUNTERIne Moors

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Clinical significance of TARP expression in pediatric acute myeloid leukemia

B. DepreterBarbara De MoerlooseKarl VandepoeleA. UyttebroeckA. Van DammeB. DenysL. DedekenM. -F. DresseJ. Van der Werff Ten BoschM. Hofmans et al.

Clinical significance of TARP expression in pediatric acute myeloid leukemia

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeBarbara DenysLaurence DedekenMarie-Françoise DresseJutte Van Der Werff Ten BoschMattias Hofmans et al.

A1 Journal Article in HEMASPHERE

Leukaemic stem cells in AML : where are we now? An update on recent findings and detection

Barbara DepreterBarbara De MoerlooseJan PhilippéTim Lammens

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib : a report from the I-CML-Ped Study

Deborah MeyranArnaud PetitJoelle GuilhotMeinolf SuttorpPetr SedlacekEveline De BontChi Kong LiKrzysztof KalwakBrigitte LausenSrdjana Culic et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Not all pediatric intestinal polyps are alike

Drieke VermeulenMyriam Van WinckelSaskia Vande VeldeRuth De BruyneStephanie Van BiervlietBarbara De MoerlooseLucas E MatthyssensKatrien Van RenterghemDirk Van de Putte

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Pediatric randomized trial EORTC CLG 58951 : outcome for adolescent population with acute lymphoblastic leukemia

Laura Olivier-GougenheimChloe ArfeuilleStefan SuciuNicolas SirventGenevieve PlatAlina FersterBarbara De MoerlooseCarine DomenechAnne UyttebroeckPierre-Simon Rohrlich et al.

A1 Journal Article in HEMATOLOGICAL ONCOLOGY

Prospective, real-time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma in Belgium

Veerle MondelaersAlina FersterAnne UyttebroeckBenedicte BrichardJuttevan der Werff ten BoschKoenraad NorgaNadine FrancotteCaroline PietteKatrien VandemeulebroeckeCharlotte Verbeke et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Retrospective analysis of the incidence and characteristics of paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia in Belgium

Lindsey De SmaeleMattias HofmansTim LammensA Van DammeJutte van der Werff ten BoschA FersterJoris VerlooyC ChantrainJan PhilippéNadine Van Roy et al.

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency

Emilia J. KozyraVictor B. PastorStylianos LefkopoulosSushree S. SahooHauke BuschRebecca K. VossMiriam ErlacherDirk LebrechtEnikoe A. SzvetnikShinsuke Hirabayashi et al.

A1 Journal Article in LEUKEMIA

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtJulie MorscioLindy ReunesJuliette RoelsValentina BardelliBéatrice LintermansWouter Van LoockeAfonso AlmeidaLaurence C. CheungRishi S. Kotecha et al.

A1 Journal Article in BLOOD

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Barbara DepreterKarin WeeningKarl VandepoeleMagnus EssandBarbara De MoerlooseMaria ThemeliJacqueline CloosDiana HanekampIne MoorsINGE D'HONT et al.

A1 Journal Article in HAEMATOLOGICA

The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing

L ZubovicS PiazzaT TebaldiL CozzutoG PalazzoV SidarovichV De SanctisR BertorelliTim LammensMattias Hofmans et al.

A1 Journal Article in JOURNAL OF HEMATOLOGY & ONCOLOGY

2019

Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia

Ditte JA LohmannPeter H AsdahlJonas AbrahamssonShau-Yin HaOlafur G JonssonGertjan JL KaspersMinna KoskenvuoBirgitte LausenBarbara De MoerlooseJosefine Palle et al.

A1 Journal Article in CANCER MEDICINE

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte Van der Werff Ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De Moerloose et al.

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte van der Werff ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De Moerloose et al.

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria MilaniFilip MatthijssensWouter Van LoockeKaat DurinckJuliette RoelsSofie PeirsMorgan ThénozTim PietersLindy ReunesBéatrice Lintermans et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia : proof of concept study

Mattias HofmansBarbara DepreterTim LammensHelene CaveChristian FlothoHenrik HasleValerie de HaasCharlotte M. NiemeyerJan StaryPieter Van Vlierberghe et al.

Noonan syndrome-associated myeloproliferative disorder with somatically acquired monosomy 7 : impact on clinical decision making

Mattias HofmansRieke SchroederTim LammensChristian FlothoCharlotte NiemeyerNadine Van RoyWim DecaluweJan PhilippéBarbara De Moerloose

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia : a global, single-arm, phase 2 trial

Theodore W. LaetschGary Douglas MyersAndre BaruchelAndrew C. DietzMichael A. PulsipherHenrique BittencourtJochen BuechnerBarbara De MoerlooseKara L. DavisEneida Nemecek et al.

A1 Journal Article in LANCET ONCOLOGY

Phase I dose‐escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors

François DozFranco LocatelliAndré BaruchelNicolas BlinBarbara De MoerlooseDidier FrappazMichael DworzakMatthias FischerJan StaryRene Fuertig et al.

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01

Barbara De MoerlooseArdine ReedijkGeertruida H. de BockTim LammensValerie de HaasBarbara DenysLaurence DedekenMarry M. van den Heuvel-EibrinkMaroeska te LooAnne Uyttebroeck et al.

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL)

Mattias HofmansStefan SuciuAlina FersterPieter Van VlierbergheFrançoise MazingueNicolas SirventVitor CostaKarima YakoubenCatherine PaillardAnne Uyttebroeck et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

TARP as immunotherapeutic target in AML expressed in the LSC compartment

Barbara DepreterKarin WeeningKarl VandepoeleM EssandBarbara De MoerlooseM ThemeliJ CloosD HanekampIne MoorsINGE D'HONT et al.

The strategic plan for paediatric cancer treatment in Belgium

A Van DammeBarbara De MoerlooseB BrichardA FersterB HeenenGenevieve LaureysKoen NorgaC PietteJutte Van Der Werff Ten BoschAnne Uyttebroeck

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Use of granulocyte colony-stimulating factor and risk of relapse in pediatric patients treated for acute myeloid leukemia according to NOPHO-AML 2004 and DB AML-01

Ditte JA LohmannPeter H AsdahlJonas AbrahamssonShau-Yin HaOlafur G JonssonGertjan JL KaspersMinna KoskenvuoBirgitte LausenBarbara De MoerlooseJosefine Palle et al.

A1 Journal Article in PEDIATRIC BLOOD & CANCER

2018

A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T- and B-cell acute lymphoblastic leukemias in vivo

Hien Anh NguyenYing SuJenny Yu ZhangAleksandar AntanasijevicMichael CaffreyAmanda M SchalkLi LiuDamiano RondelliAnnie OhDolores L Mahmud et al.

A1 Journal Article in CANCER RESEARCH

Aandachtspunten bij een therapie met voriconazole

Franky BuyleKatleen Van ButseleS MertensBarbara De MoerlooseDirk VogelaersL Van Der LindenI SprietAnnemie Somers

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Associations between neutrophil recovery time, infections and relapse in pediatric acute myeloid leukemia

Ditte JA LøhmannPeter H AsdahlJonas AbrahamssonShau-Yin HaÓlafur G JónssonGertjan JL KaspersMinna KoskenvuoBirgitte LausenBarbara De MoerlooseJosefine Palle et al.

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Cancer-related mRNA expression analysis using a novel flow cytometry-based assay

Barbara DepreterJan PhilippéMAGALI MEULBarbara DenysKarl VandepoeleBarbara De MoerlooseTim Lammens

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Compatibility of baclofen, carvedilol, hydrochlorothiazide, mercaptopurine, methadone hydrochloride, oseltamivir phosphate, phenobarbital, propranolol hydrochloride, pyrazinamide, sotalol hydrochloride, spironolactone, Tacrolimus monohydrate, ursodeoxycholic acid, and vancomycin hydrochloride oral suspensions compounded with SyrSpend SF pH4

H PoloniniS L Da SilvaM A F BrandaoTieneke BautersBarbara De MoerlooseA O Ferreira

A2 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICAL COMPOUNDING

Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia. A NOPHO-DBH-AML study

Ninna BagerKristian L. Juul-DamJulie D. SandahlJonas AbrahamssonBerna BeverlooEveline S. J. M. de BontShau-Yin HaKirsi JahnukainenOlafur G. JonssonGertjan L. Kaspers et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Differences in infection prophylaxis measures between paediatric acute myeloid leukaemia study groups within the international Berlin-Frankfurt-Munster (I-BFM) study group

Kim KleinHenrik HasleJonas AbrahamssonBarbara De MoerlooseGertjan J. L. Kaspers

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Exploring the long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensS BresolinH CavéC FlothoH HasleHetty HelsmoortelM Van den Heuvel-EibrinkC NiemeyerJ Stary et al.

Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia

Elena J. OrlandoXia HanCatherine TribouleyPatricia A. WoodRebecca J. LearyMarkus RiesterJohn E. LevineMuna QayedStephan A. GruppMichael Boyer et al.

A1 Journal Article in NATURE MEDICINE

Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients

Diana HanekampBarbara DenysGertjan JL KaspersJeroen G te MarveldeGerrit Jan SchuurhuisValerie De HaasBarbara De MoerlooseEveline S de BontC Michel ZwaanAnja de Jong et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Oral microbiota reduce wound healing capacity of epithelial monolayers, irrespective of the presence of 5-fluorouracil

Eline VanlanckerBarbara VanhoeckeTom SieprathJanie BourgeoisAnnelore BeteramsBarbara De MoerlooseWinnok De VosTom Van de Wiele

A1 Journal Article in EXPERIMENTAL BIOLOGY AND MEDICINE

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtSofie PeirsJulie MorscioFilip MatthijssensJuliette RoelsLindy ReunesBéatrice LintermansSteven GoossensTim LammensNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML : a retrospective study by the I-BFM Study Group

Sanne NoortMartin ZimmermannDirk ReinhardtWendy CuccuiniMartina PigazziJenny SmithRhonda E. RiesTodd A. AlonzoBetsy HirschDaisuke Tomizawa et al.

A1 Journal Article in BLOOD

Recurrently affected genes in juvenile myelomonocytic leukaemia

Julia C ObenauerFrancois G KavelaarsMathijs A SandersAndrica CH de VriesValerie de HaasH Berna BeverlooBarbara De MoerlooseTim LammensMichael DworzakRemco M Hoogenboezem et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Retrospective study of infant leukaemia in the University Hospitals of Leuven and Ghent

Barbara De MoerlooseE NauwynckK ArtsLeen WillemsV LabarqueTim LammensA Uyttebroeck

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

RNA-based FLT3-ITD allelic ratio is associated with outcome and ex vivo response to FLT3 inhibitors in pediatric AML

David G. J. CucchiBarbara DenysGertjan J. L. KaspersJeroen J. W. M. JanssenGert J. OssenkoppeleValerie de HaasC. Michel ZwaanMarry M. van den Heuvel-EibrinkJan PhilippéTamas Csikos et al.

A1 Journal Article in BLOOD

The genetic basis and cell of origin of mixed phenotype acute leukaemia

Thomas B. AlexanderZhaohui GuIlaria IacobucciKirsten DickersonJohn K. ChoiBeisi XuDebbie Payne-TurnerHiroki YoshiharaMignon L. LohJohn Horan et al.

A1 Journal Article in NATURE

The impact of chemotherapy on the host microbiota in the context of oral and gastrointestinal mucositis

Eline VanlanckerBarbara VanhoeckeBarbara De MoerlooseTom Van de Wiele

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensHetty HelsmoortelSilvia BresolinHélène CavéChristian FlothoHenrik HasleMarry M van den Heuvel-EibrinkCharlotte NiemeyerJan Stary et al.

A1 Journal Article in HAEMATOLOGICA

Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia

SL MaudeTW LaetschJ BuechnerS RivesM BoyerH BittencourtP BaderMR VernerisHE StefanskiGD Myers et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

2017

Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia : the experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents

Frédéric MillotChristelle DuprazJoelle GuilhotMeinolf SuttorpFrançoise BrizardThierry LeblancAdalet Meral GünesPetr SedlacekEvelyne De BontChi Kong Li et al.

A1 Journal Article in CANCER

Bijwerkingen van 'immune checkpoint' inhibitoren : waar dient een huisarts alert op te zijn?

S De KeukeleireTessa KerrePiet OstBarbara De MoerlooseKarim VermaelenLieve BrochezVibeke Kruse

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Characteristics and outcome in patients with central nervous system involvement treated in European pediatric acute myeloid leukemia study groups

Ursula CreutzigMichael N DworzakMartin ZimmermannDirk ReinhardtLucie SramkovaJan Pierre BourquinHenrik HasleJonas AbrahamssonGertjan KaspersMary M van den Heuvel et al.

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Digital multiplex ligation-dependent probe amplification for detection of key copy number alterations in T- and B-cell lymphoblastic leukemia

Anne Benard-SlagterIlse ZondervanKarel de GrootFarzaneh GhazaviVirinder SarhadiPieter Van VlierbergheBarbara De MoerlooseClaire SchwabKim VettenrantaChristine J Harrison et al.

A1 Journal Article in JOURNAL OF MOLECULAR DIAGNOSTICS

Genetic insights in ETV6/RUNX1-positive B-cell precursor acute lymphoblastic leukaemia

Farzaneh GhazaviTim LammensPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Novel molecular genetic insights in paediatric B-cell precursor acute lymphoblastic leukaemia

Farzaneh GhazaviTim LammensPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Prognostic discrimination based on the EUTOS long-term survival score within the International Registry for Chronic Myeloid Leukemia in children and adolescents

Frédéric MillotJoëlle GuilhotMeinolf SuttorpAdalet Meral GünesPetr SedlacekEveline De BontChi Kong LiKrzysztof KalwakBirgitte LausenSrdjana Culic et al.

A1 Journal Article in HAEMATOLOGICA

Prolonged versus standard native E-coli asparaginase therapy in childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma : final results of the EORTC-CLG randomized phase III trial 58951

Veerle MondelaersStefan SuciuBarbara De MoerlooseAlina FersterFrancoise MazingueGeneviève PlatKarima YakoubenAnne UyttebroeckPatrick LutzVitor Costa et al.

A1 Journal Article in HAEMATOLOGICA

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia

Daniel B LipkaTania WitteReka TothJing YangManuel WiesenfarthPeter NoellkeAlexandra FischerDavid BrocksZuguang GuJeongbin Park et al.

A1 Journal Article in NATURE COMMUNICATIONS

The ION-Ghent guidelines for the management of immune related adverse events (irAE's)

Vibeke KruseMax SchreuerKarim VermaelenPiet OstTessa KerreBarbara De MoerlooseLieve Brochez

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Unravelling the biology of juvenile myelomonocytic leukaemia using transcriptomics

Hetty HelsmoortelTim LammensPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

2016

A novel multiplex NGS-based digital MLPA assay for copy number detection of 700 target sequences in childhood acute lymphoblastic leukemia

Anne BenardIlse ZondervanJan SchoutenKarel de GrootFarzaneh GhazaviVirinder SarhadiPieter Van VlierbergheBarbara De MoerlooseChristine HarrisonClaire Schwab et al.

Analysis of a global registration trial of the efficacy and safety of CTL019 in pediatric and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL)

Stephan A GruppTheodore LaetschJochen BuechnerHenrique BittencourtShannon L MaudeMichael R VernerisGary D MyersMichael BoyerSusana RivesBarbara De Moerloose et al.

Comparison between FLT3-ITD measurements based on RNA and DNA of childhood myeloid leukemia samples

Edwin SonneveldValerie de HaasMichel ZwaanMarry van den Heuvel-EibrinkJan PhilippéBarbara DenysBarbara De MoerlooseEveline de BontGert Jan KaspersJacqueline Cloos

Digital MLPA(TM) for copy number detection in childhood acute lymphoblasic leukemia : a novel multiplex NGS-based assay

A BenardBarbara De MoerlooseI ZondervanFarzaneh GhazaviV SarhadiPieter Van VlierbergheTim LammensS KnuutilaS Savola

Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia

Gloria MilaniKaat DurinckFilip MatthijssensSofie PeirsTim PietersLindy ReunesBéatrice LintermansNiels VandammeTim LammensYunlei Li et al.

Genomic landscape of pediatric mixed phenotype acute leukemia

Thomas B AlexanderZhaohui GuJohn K ChoiMignon LohJohn HoranBarbara BuldiniGiuseppe BassoSarah ElitzurValerie de HaasC Michel Zwaan et al.

Identification of candidate oncogenes and chromosomal breakpoint sequencing by targeted locus amplification in T-cell acute lymphoblastic leukemia

Eric VroegindeweijTim LammensKirsten Cante-BarrettErik SplinterA UyttebroeckJessica GC Buijs-GladdinesWilco SmitsPeter VandenbergheRenate De SmedtBarbara De Moerloose et al.

Impact of age and treatment group in childhood high hyperdiploid low risk B-cell acute lymphoblastic leukemia (ALL) : results of the CLG-EORTC 58951 study

Laura ClementStefan SuciuIsabelle LuquetAlina FersterKarima YakoubenAnne UytterbroeckCatherine PaillardNicolas SirventVitor CostaBarbara De Moerloose et al.

Impact of somatic mutations on the outcome of children and adolescents with therapy-related myelodysplastic syndrome

Brigitte StrahmMarcin W WlodarskiVictor B PastorBart PrzychodzienAlbert CatalaMichael DworzakOksana FabriHenrik HasleKristian KallayRiccardo Masetti et al.

Leukemia in infants : a retrospective study (1992-2014) in the Ghent University Hospital

Elise NauwynckTim LammensVincent VakaetN Van DammeYves BenoitVeerle MondelaersEls VandecruysGenevieve LaureysL VakaetBarbara De Moerloose

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19

Hetty HelsmoortelBarbara De MoerlooseTim PietersFarzaneh GhazaviSilvia BresolinHelene CaveAndrica de VriesValerie de HaasChristian FlothoVeerle Labarque et al.

A1 Journal Article in HAEMATOLOGICA

LIN28B is overexpressed in pediatric leukemia and regulates LNCRNA H19

Hetty HelsmoortelBarbara De MoerlooseSilvia BresolinHélèe CavéChristian FlothoCharlotte NiemeyerJan StaryMarry van den Heuvel-EibrinkPieter Van VlierbergheTim Lammens

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Hetty HelsmoortelSilvia BresolinTim LammensHélène CavéPeter NoellkeAurélie CayeFarzaneh GhazaviAndrica de VriesHenrik HasleVeerle Labarque et al.

A1 Journal Article in BLOOD

Mutation landscape in childhood myelodysplastic syndromes : results from EWOG-MDS

Marcin WlodarskiVictor PastorJan StarýRiccardo MasettiHenrik HasleMichael DworzakMarkus SchmuggeBarbara De MoerlooseMarek UssowiczMarry van den Heuvel-Eibrink et al.

Novel molecular genetic insights in pediatric B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerloosePieter Van VlierbergheTim Lammens

Phase I study to evaluate dose, safety and tolerability of the polo-like kinase inhibitor Volasertib in paediatric patients with acute leukaemia and advanced solid tumours

F DozF LocatelliA BaruchelN BlinBarbara De MoerlooseD FrappazM DworzakM FischerJ StarýK Riemann et al.

Prevalence, clinical characteristics and prognosis of GATA2-related myelodysplastic syndromes (MDS) in children and adolescents

Marcin W WlodarskiShinsuke HirabayashiVictor PastorJan StarýHenrik HasleRiccardo MasettiMichael DworzakMarkus SchmuggeMarry van den Heuvel-EibrinkMarek Ussowicz et al.

A1 Journal Article in BLOOD

Prognostic discrimination of children and adolescents with chronic myeloid leukemia based on the EUTOS Long Term Survival (ELTS) score

Frédéric MillotJoelle GuilhotMeinolf SuttorpAdalet Meral GünesPetr SedlacekEveline de BontChi Kong LiKrzysztof KalwakBirgitte LausenSrdjana Culic et al.

RPPA-Based protein profiling reveals enhanced PI3K/AKT/mTOR signaling in ETV6/RUNX1-positive acute lymphoblastic leukemia patients with low CD200 expression

Farzaneh GhazaviValentina SerafinPieter RondouTim LammensFranki SpelemanBenedetta AccordiBarbara De MoerloosePieter Van Vlierberghe

The integrated immunological signature of Refractory Cytopenia of Childhood (RCC)

D de WinterAW LangerakJJM van DongenM DworzakBarbara De MoerlooseJ StarýCM NiemeyerF LocatelliH HasleM Schmugge et al.

Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG-MDS study group

Annamaria M CsehCharlotte M NiemeyerAyami YoshimiAlbert CatalaMichael C FrühwaldHenrik HasleMary M van den Heuvel-EibrinkMelchior LautenBarbara De MoerlooseOwen P Smith et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne UyttebroeckFilip Van Nieuwerburgh et al.

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertHetty HelsmoortelAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne Uyttebroeck et al.

A1 Journal Article in ONCOTARGET

Unraveling the biology of juvenile myelomonocytic leukemia using transcriptomics

Hetty HelsmoortelBarbara De MoerlooseTim LammensPieter Van Vlierberghe

2015

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood

Anna M AalbersMarry M van den Heuvel-EibrinkIrith BaumannMichael DworzakHenrik HasleFranco LocatelliBarbara De MoerlooseMarkus SchmuggeEster MejstrikovaMichaela Nováková et al.

A1 Journal Article in HAEMATOLOGICA

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Farzaneh GhazaviEmmanuelle ClappierTim LammensStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitOdile Minckes et al.

A1 Journal Article in HAEMATOLOGICA

Clinical impact of additional cytogenetic aberrations, cKIT and RAS mutations, and treatment elements in pediatric t(8;21)-AML : results from an international retrospective study by the International Berlin-Frankfurt-Münster study group

Kim KleinGertjan KaspersChristine J HarrisonH Berna BeverlooArdine ReedijkMathilda BongersJacqueline CloosAndrea PessionDirk ReinhardtMartin Zimmerman et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Clonal mutational landscape of childhood myelodysplastic syndromes

Emilia J KozyraShinsuke HirabayashiVictor Bengt Pastor LoyolaBartlomiej PrzychodzenAxel KarowAlbert CatalaBarbara De MoerlooseMichael DworzakHenrik HasleRiccardo Masetti et al.

Collaborative efforts driving progress in pediatric acute myeloid leukemia

C Michel ZwaanEdward A KolbDirk ReinhardtJonas AbrahamssonSouichi AdachiRichard AplencEveline SJM De BontBarbara De MoerlooseMichael DworzakBrenda ES Gibson et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia

Charlotte M NiemeyerMignon L LohAnnamaria CsehTodd CooperChristopher C DvorakRebecca ChanBlanca XicoyUlrich GermingSeiji KojimaAtsushi Manabe et al.

A1 Journal Article in HAEMATOLOGICA

Excellent outcome in pediatric AML with response guided chemotherapy without allogeneic HSCT in first complete remission results from prococol DB-AML01

Eveline de BontArdine ReedijkTim LammensValerie de HaasBarbara DenysLaurence DedekenMarry van den HeuvelMaroeska te LooAnne UyttebroeckAn Vandamme et al.

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

Hiroto InabaYinmei ZhouOusama AblaSouichi AdachiAnne AuvrignonH Berna BeverlooEveline de BontTai-Tsung ChangUrsula CreutzigMichael Dworzak et al.

A1 Journal Article in BLOOD

IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Chrildren's Leukemia Group study 58951

E ClappierN GrardelM BakkusJ RapionBarbara De MoerlooseP KastnerA CayeJ ViventV CostaA Ferster et al.

A1 Journal Article in LEUKEMIA

Long-term results of the 'Prospective study of the diagnosis and treatment of myelodysplastic syndromes in childhood (EWOG-MDS98)'

A StraussA YoshimiI BaumannM UssowiczBarbara De MoerlooseB SchlegelbergerM DworzakM SchmuggeM ZeccaA Fischer et al.

MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

Evelien MetsJoni Van der MeulenGert Van PeerMichael BoicePieter MestdaghInge Van de WalleTim LammensSteven GoossensBarbara De MoerlooseYves Benoit et al.

A1 Journal Article in LEUKEMIA

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviTim LammensNadine Van RoyBruce PoppeFranki SpelemanYves BenoitPieter Van VlierbergheBarbara De Moerloose

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

Mutational spectrum of juvenile myelomonocytic leukemia

J ObenauerF KavelaarsACH de VriesM SandersV de HaasBarbara De MoerlooseTim LammensM DworzakC NiemeyerP Valk et al.

Novel biological insights in T-cell acute lymphoblastic leukemia

Kaat DurinckSteven GoossensSofie PeirsAnnelynn WallaertWouter Van LoockeFilip MatthijssensTim PietersGloria MilaniTim LammensPieter Rondou et al.

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

Phase II study on bortezomib (BTZ) in multiple relapsed or refractory pediatric acute lymphoblastic leukemia (rALL) : high response rate with a modestly intensive regimen including BTZ, not related to pharmacokinetics

Gertjan JL KaspersDenise NiewerthBram WilhelmSatianand RamnarainHans BerkhofValerie de HaasRon AA MathôtAndishe AttarbaschiAndre BaruchelEveline S de Bont et al.

Somatic genetic and epigenetic architecture of myelodysplastic syndromes arising from GATA2 deficiency

Victor Bengt Pastor LoyolaShinsuke HirabayashiSandra PohlEmilia J KozyraAlbert CatalaBarbara De MoerlooseMarek DworzakHenrik HasleRiccardo MasettiMarkus Schmugge et al.

Switch to subsequent line of treatment in children and adolescents with chronic myeloid leukemia (CML) treated with imatinib : experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents (I-CML-Ped study)

Frédéric MillotJoelle GuilhotMeinolf SuttorpAnne Sophie MeunierGunes Adalet MeralPer SedlacekEveline de BontChi Kong LiKrzysztof KalwakBrigitte Lausen et al.

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der MeulenViraj SanghviKonstantinos MavrakisKaat DurinckFang FangFilip MatthijssensPieter RondouMonica RosenTim PietersPeter Vandenberghe et al.

A1 Journal Article in BLOOD

The integrated immunological signature of refractory cytopenia of childhood (RCC)

Demi de WinterMarry M van den Heuvel-EibrinkVincent HJ van der VeldenAnton W LangerakJacques JM van DongenMichael DworzakBarbara De MoerlooseJan StarýCharlotte M NiemeyerFranco Locatelli et al.

The long non-coding RNA H19 is regulated by LIN28B

Hetty HelsmoortelBarbara De MoerlooseTim PietersFarzaneh GhazaviS BresolinH CavéA CayeACH de VriesC FlothoV Labarque et al.

The relevance of stem cell load at diagnosis for the development of relapse in pediatric acute myeloid leukemia

Dirkje W HanekampBarbara DenysGerjan JL SchuurhuisJeroen G te MarveldeValerie de HaasBarbara De MoerlooseEveline S de BontAnja de JongJan PhilippéJacqueline Cloos et al.

2014

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in early immature T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensSteven GoossensKirsten Canté-BarrettTim LammensBarbara De MoerlooseYves BenoitJean SoulierBruce PoppeTom Taghon et al.

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensSteven GoossensInge Van de WalleKatia RuggeroCharles E de BockSandrine DegryseKirsten Canté-BarrettDelphine BriotEmmanuelle Clappier et al.

A1 Journal Article in BLOOD

ABT-199 mediated inhibition of BCL2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensSteven GoossensCharles De BockKirsten Canté-BarrettTim LammensInge Van de WalleBarbara De MoerlooseYves BenoitBruce Poppe et al.

Anthracycline type during induction associated with outcome in pediatric t(8;21) and inv(16) AML

Henrik HasleJonas AbrahamssonEvelina S De BontValerie de HaasBarbara De MoerlooseErik ForestierShau Yin HaJesper HeldrupKirsi JahnukainenOlafur G Jonsson et al.

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood

Anna AalbersMarry Van Den Heuvel-EibrinkIrith BaumannMichael DworzakHenrik HasleFranco LocatelliBarbara De MoerlooseMarkus SchmuggeEster MejstrikovaMichaela Novakova et al.

Clinical impact of additional cytogenetic aberrations, cKIT- and RAS mutations and other factors in pediatric t(8;21)-AML

Kim KleinGertjan KaspersChristine J HarrisonBerna BeverlooArdine ReedijkMathilda BongersJacqueline CloosAndrea PessionDirk ReinhardtMartin Zimmermann et al.

Comparison of horse and rabbit antithymocyte globulin in immunosuppressive therapy for refractory cytopenia of childhood

Ayami YoshimiMarry M van den Heuvel-EibrinkIrith BaumannStephan SchwarzIngrid Simonitsch-KluppPascale De PaepeVit CamprGitte Birk KerndrupMaureen O'SullivanRita Devito et al.

A1 Journal Article in HAEMATOLOGICA

Dexamethasone (6 mg/m²/day) and prednisolone (60 mg/m²/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial

Carine DomenechStefan SuciuBarbara De MoerlooseFrançoise MazingueGeneviève PlatAlina FersterAnne UyttebroeckNicolas SirventPatrick LutzKarima Yakouben et al.

A1 Journal Article in HAEMATOLOGICA

Fatal Myceliophthora thermophila infection in a boy with acute myeloid leukaemia and cord blood stem cell transplantation

A PietteBarbara De MoerloosePetra SchelstraeteMaria Bordon Cueto De BraemThierry De BaereGeert Claeys

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Impact of minimal residual disease monitoring on therapy in Belgian childhood acute lymphoblastic leukaemia

J Van der StraetenBarbara De MoerlooseMF DresseS DupontA FersterP PhilippetA UyttebroeckJ van der Werff ten BoschC DemanetYves Benoit et al.

Juvenile myelomonocytic leukaemia: the quest for more specific therapies

Hetty HelsmoortelTim LammensNadine Van RoyJan PhilippéPascale De PaepeYves BenoitFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Juvenile myelomonocytic leukemia : five genes, how many subtypes?

Charlotte M NiemeyerBrigitte StrahmMichael DworzakBarbara De MoerlooseHenrik HasleJan StaryMarkus SchmuggeMarek UssowicsMarry Van Den Heuvel-EibrinkMarco Zecca et al.

LIN28B defines an aggressive subtype of juvenile myelomonocytic leukemia

Hetty HelsmoortelTim LammensFarzaneh GhazaviAurelie CayeHélène CavéChristian FlothoCharlotte NiemeyerJan StarySilvia BresolinRiccardo Masetti et al.

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

Evelien MetsGert Van PeerJoni Van der MeulenMichael BoiceTom TaghonSteven GoossensPieter MestdaghYves BenoitBarbara De MoerlooseNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA

Mind the gap : translation of genetic research into clinical care in the context of RUNX1-associated leukaemia predisposition

Tim RippergerAlina FersterTim LammensBarbara De MoerlooseLaurence RozenNadira AzziCharlotte M NiemeyerBrigitte SchlegelbergerDoris Steinemann

Minimal residual disease quantification by PCR in childhood acute lymphoblastic leukaemia

J Van der StraetenBarbara De MoerlooseMF DresseS DupontA FersterP PhilippetA UyttebroeckJ van der Werff ten BoschC DemanetYves Benoit et al.

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Pediatric acute megakaryoblastic leukemia without Down syndrome: a retrospective study by the international Berlin-Frankfurt-Munster study group (I-BFMSG)

Hiroto InabaYinmei ZhouOussama AblaSouichi AdachiAnne AuvrignonBerna BeverlooEveline De BontTai-Tsung ChangUrsula CreutzigNicole Dastugue et al.

Prognostic relevance of BTLA/CD200 deletion in pediatric pre-B cell acute lymphoblastic leukemia

Farzaneh GhazaviTim LammensStefan SuciuMarleen BakkusHélène CavéFranki SpelemanYves BenoitBarbara De MoerloosePieter Van Vlierberghe

Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol

Farzaneh GhazaviTim LammensEmmanuelle ClappierStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitYves Bertrand et al.

RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia

Anna R PoetschDaniel B LipkaTania WitteRainer ClausPeter NöllkeManuela ZucknickChristiane Olk-BatzSilvia FluhrMichael DworzakBarbara De Moerloose et al.

A1 Journal Article in EPIGENETICS

Reduced intensity conditioning for children with refractory cytopenia of childhood : results of the EWOG-MDS study SCT RX RIC 06

Brigitte StrahmPeter BaderAlbert CatalaMichael DworzakMarry VandenheuvelBarbara De MoerlooseMarkus SchmuggeOwen SmithPetr SedlacekFranco Locatelli et al.

Results of a feasibility and phase II study on bortezomib (BTZ) in pediatric multiply relapsed of refractory acute lymphoblastic leukemia: complete hematological responses with a modestly intensive regimen including BTZ

Gertjan KaspersDenise NiewerthSatianand RamnarainAndishe AttarbaschiAndré BaruchelEvelina S De BontFranca FagioliBarbara De MoerlooseKarsten NysomGiuseppe Palumbo et al.

T-cell receptor Vβ skewing frequently occurs in refractory cytopenia of childhood and is associated with an expansion of effector cytotoxic T cells: a prospective study by EWOG-MDS

AM AalbersMM van den Heuvel-EibrinkI BaumannHB BeverlooGJ DriessenM DworzakA FischerG GöhringH HasleF Locatelli et al.

A1 Journal Article in BLOOD CANCER JOURNAL

The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS

AM AalbersVHJ van der VeldenA YoshimiA FischerP NoellkeCM ZwaanI BaumannHB BeverlooM DworzakH Hasle et al.

A1 Journal Article in LEUKEMIA

The prognostic value of leukemic stem cells in pediatric AML

Bram De CaluwéRolf WoutersValerie De HaasJeroen G te MarveldeBarbara De MoerlooseEveline S de BontBarbara DenysAnja De JongG KaspersJan Philippé et al.

Use of rasburicase in prevention and treatment of tumor lysis syndrome in children

Tieneke BautersVeerle MondelaersYves BenoitJ VandenbrouckeBarbara De Moerloose

2013

Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood

AM AalbersMM van den Heuvel-EibrinkV de HaasJG te MarveldeAX de JongM van der BurgM DworzakH HasleF LocatelliBarbara De Moerloose et al.

A1 Journal Article in LEUKEMIA

Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood

A AalbersM Van Den Heuvel-EibrinkV HaasJ te MarveldeA de JongM van der BurgM DworzakH HasleF LocatelliBarbara De Moerloose et al.

Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood

AM AalbersMM Van den Heuvel-EibrinkV De HaasJG Te MarveldeAX De JongM van der BurgM DworzakH HasleF LocatelliBarbara De Moerloose et al.

Congenital neutropenia

Barbara De Moerloose

A2 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE

Cost-minimisation of PEG-L-asparaginase versus native L-asparaginase for the treatment of children with acute lymphoblastic leukemia in Belgium

Tieneke BautersVeerle MondelaersBarbara De MoerlooseHugo RobaysYves Benoit

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Delayed elemination of methotrexate by cola beverages in a pediatric acute lymphoblastic leukemia population

Tieneke BautersTim LammensPauline BelinYves BenoitHugo RobaysBarbara De Moerloose

A1 Journal Article in LEUKEMIA & LYMPHOMA

Highly elevated liver enzymes related to the use of gabapentin in a child treated for high-risk neuroblastoma

Tieneke BautersBarbara De MoerlooseHugo RobaysYves BenoitGenevieve Laureys

Impact of MRD status prior to HSCT in pediatric AML

M HansenC NyvoldL EbbesenD ReinhardtG KaspersJ StaryBarbara De MoerlooseM DworzakC ZwaanH Hasle

Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia

Tieneke BautersVeerle MondelaersHugo RobaysHans De WildeYves BenoitBarbara De Moerloose

A1 Journal Article in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY

MiR-128 is a novel PHF6 targeting regulatory non-coding RNA acting as a T-ALL oncogene

Evelien MetsJoni Van der MeulenGert Van PeerMichael BoicePieter MestdaghTom TaghonDavid AvranBarbara De MoerlooseYves BenoitBruce Poppe et al.

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty HelsmoortelTim LammensPieter MestdaghNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitJo VandesompeleFranki SpelemanPieter Van Vlierberghe et al.

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty HelsmoortelTim LammensPieter MestdaghNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitJo VandesompeleFranki SpelemanPieter Van Vlierberghe et al.

Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International Berlin-Frankfurt-Munster AML-study group

Eva A CoenenC Michel ZwaanDirk ReinhardtChristine J HarrisonOskar A HaasValerie de HaasVladimir MihálBarbara De MoerlooseMarta JeisonJeffrey E Rubnitz et al.

A1 Journal Article in BLOOD

Pediatric acute myeloid leukemia with t(8;16)(p11;p13): a distinct clinical and biological entity: results of a collaborative study by the international Berlin-Frankfurt-Münster AML Study Group

E CoenenCM ZwaanD ReinhardtC HarrisonO HaasV De HaasV MihalBarbara De MoerlooseM JeisonJ Rubnitz et al.

PEG-asparaginase in treatment of childhood acute lymphoblastic leukemia

Veerle MondelaersTieneke BautersBarbara De MoerlooseYves Benoit

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

SNX10 mutations define a subgroup of human Autosomal Recessive Osteopetrosis with variable clinical severity

Alessandra PangrazioAnders FasthAndrea SbardellatiPaul J OrchardKimberly A KasowJamal RazaCanan AlbayrakDavut AlbayrakOlivier VanakkerBarbara De Moerloose et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood : a prospective study by EWOG-MDS

A AalbersV Van Der VeldenA YoshimiA FischerP NoellkeC ZwaanI BaumannH BeverlooM DworzakH Hasle et al.

The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS

AM AalbersVHJ Van der VeldenA YoshimiA FischerP NoellkeCM ZwaanI BaumannHB BeverlooM DworzakH Hasle et al.

2012

Improved risk stratification and outcome prediction in children with average risk 1 precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Farzaneh GhazaviTim LammensStefan SuciuGenevieve LaureysMarleen BakkusAlina FersterAnne UyttebroeckPatrick LutzHélène CavéGeneviève Plat et al.

Improved risk-stratification and outcome prediction in children with average risk precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Farzaneh GhazaviTim LammensStefan SuciuGenevieve LaureysMarleen BakkusAlina FersterAnne UyttebroeckPatrick LutzHélène CavéGeneviève Plat et al.

Methotrexate in children with acute lymphoblastic leukaemia : impact of pharmacogenetic polymorphisms on plasma concentration, toxicity and outcome

Lien CattoirLiesbeth HuysPaul CouckeYves BenoitTieneke BautersBarbara De Moerloose

Musculoskeletal manifestations in children with acute lymphoblastic leukaemia

HILDE MULDERNele HerregodsVeerle MondelaersYves BenoitVALERIE MEERSSCHAUTBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

Shinsuke HirabayashiChristian FlothoJessica MoetterMichael HeuserHenrik HasleBernd GruhnThomas KlingebielFelicitas TholBrigitte SchlegelbergerIrith Baumann et al.

A1 Journal Article in BLOOD

Study of the miRNome of childhood myelodysplastic syndrome

Hetty HelsmoortelTim LammensNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitFranki SpelemanBarbara De Moerloose

2011

Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome

Christiane Olk-BatzAnna R PoetschPeter NöllkeRainer ClausManuela ZucknickInga SandrockTania WitteBrigitte StrahmHenrik HasleMarco Zecca et al.

A1 Journal Article in BLOOD

Etoposide in continuous infusion: practical recommendations for pediatric protocols

Tieneke BautersJohan VandenbrouckeBarbara De MoerlooseJOHAN DE PORREYves BenoitHugo Robays

A2 Journal Article in JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Hematopoietic stem cell transplantation for advanced myelodysplastic syndrome in children: results of the EWOG-MDS 98 study

B StrahmP NollkeM ZeccaET KorthofM BieringsI FurlanP SedlacekA ChybickaM SchmuggeMaria Bordon Cueto De Braem et al.

A1 Journal Article in LEUKEMIA

IER3 expression in childhood myelodysplastic syndrome

Andrica de VriesChristian M ZwaanAstric Danen-Van OorschotValerie de HaasHenrik HasleFranco LocatelliBarbara De MoerlooseSophia PolychronopoulouJan StaryMarkus Schmugge et al.

Immunosuppressive therapy with anti-thymocyte globin and cyclosporine A in patients with refractory cytopenia in childhood

A Yoshimi-NollkeMM van den Heuvel-EibrinkI BaumannM FuhrerBarbara De MoerlooseM DworzakJ StaryM SchmuggeM ZeccaP Nollke et al.

Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia

Tieneke BautersVeerle MondelaersHugo RobaysHans De WildeYves BenoitBarbara De Moerloose

A1 Journal Article in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY

MicroRNA-based diagnosis, prognosis and treatment of paediatric acute lymphoblastic leukaemia

Tim LammensFarzaneh GhazaviFranki SpelemanYves BenoitBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Mutations of the spliceosome complex genes occur in adult patients but are very rare in children with myeloid neoplasia

Shinsuke HirabayashiJessica MoetterKenichi YoshidaMichael HeuserHenrik HasleAlexandra FischerBrigitte StrahmBrigitte SchlegelbergerIrith BaumannFelicitas Thol et al.

Off-label and unlicensed use in a pediatric hemato-oncology unit

Tieneke BautersBarbara De MoerlooseVERONIQUE VAN DE VELDEMyriam Van WinckelHugo RobaysYves BenoitJORIS VERLOOY

Similar efficacy and toxicity profile for Idarubicine and Mitoxantrone in induction and intensification treatment of children with acute myeloid leukemia (AML) or myelodysplasia (MDS): long-term results of the EORTC-CLG randomized phase III trial 58921

Barbara De MoerlooseStefan SuciuMartine MunzerCaroline PietteKarima YakoubenGenevieve MarguerittePatrick LutzAnne UyttebroeckPierre RohrlichAlina Ferster et al.

Stem cell transplantation for therapy-related myelodysplastic syndrome following treatment for childhood acute lymphoblastic leukaemia

B StrahmR AmannBarbara De MoerlooseM DworzakH HasleM SchmuggeJ StaryMM van den Heuvel-EibrinkM ZeccaF Locatelli et al.

The use of propranolol in the treatment of periocular infantile haemangiomas: a review

Ilse ClaerhoutMICHIEL BUIJSROGGEP DelbekeSOPHIE WALRAEDTSophie De SchepperBarbara De MoerlooseKatya De GrooteCHRISTIAN DECOCK

A1 Journal Article in BRITISH JOURNAL OF OPHTHALMOLOGY

Therapy-related myelodysplastic syndrome following treatment for childhood acute lymphoblastic leukemia: outcome of patients registered in the EWOG-MDS 98/06 studies

Brigitte StrahmRoland AmannBarbara De MoerlooseMichael DworzakHenrik HasleMarkus SchmuggeJan StaryMarry M Van den Heuvel-EibrikMarco ZeccaBrigitte Schlegelberger et al.

Treatment of refractory T-lymphoblastic leukaemia and lymphoma with nelarabine

Tieneke BautersHugo RobaysYves BenoitBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

2010

Asparaginase levels, antibodies and silent inactivation in childhood acute lymphoblastic leukemia

Veerle MondelaersM DewulfBrigitte WuytsBrecht De CuyperYves BenoitBarbara De Moerloose

Bresolin_2010_Gene exGene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia

Silvia BresolinMarco ZeccaChristian FlothoLuca TrentinAndrea ZangrandoLaura SainatiJan StaryBarbara De MoerlooseHenrik HasleCharlotte M Niemeyer et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Gastric ulcer in a child treated with deferasirox

Tieneke BautersVeerle MondelaersHugo RobaysKATHLEEN HUNNINCKBarbara De Moerloose

A1 Journal Article in PHARMACY WORLD & SCIENCE

Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951

Barbara De MoerlooseStefan SuciuYves BertrandFrançoise MazingueAlain RobertAnne UyttebroeckKarima YakoubenAlice FersterGeneviève MarguerittePatrick Lutz et al.

A1 Journal Article in BLOOD

Methemoglobinemia and hemolytic anemia caused by Rasburicase administration in a child with acute lymphoblastic leukemia

Tieneke BautersVeerle MondelaersHugo RobaysHans De WildeYves BenoitBarbara De Moerloose

Microrna expression in pediatric precursor-B acute lymphoblastic leukemia: biology, classification and prognosis

Tim LammensBarbara De MoerlooseJonas Van BaelenJoni Van der MeulenPieter MestdaghBruno VerhasseltJan PhilippéFranki SpelemanYves Benoit

PHF6 mutations in T-cell acute lymphoblastic leukemia

Pieter Van VlierbergheTeresa PalomeroHossein KhiabanianJoni Van der MeulenMireia CastilloNadine Van RoyBarbara De MoerlooseJan PhilippéSara Gonzalez-GarciaMaria L Toribio et al.

A1 Journal Article in NATURE GENETICS

Presentation and outcome of children with down syndrome and acute lymphoblastic leukemia in the eortc children's leukemia group protocol 58951

Veerle MondelaersBarbara De MoerlooseS SuciuA FersterP LutzA UyttebroeckD PlantazL NortonN SirventA Robert et al.

Refractory Cytopenia in Childhood (RCC) with normal karyotype is unlikely to progress to advanced MDS under a watch and wait strategy

Shinsuke HirabayashiBrigitte StrahmStephan SchwarzMarco ZeccaMarkus SchmuggeMichael DworzakMarry Van Den Heuvel-EibrinkHenrik HasleBarbara De MoerlooseJan Stary et al.

The Dutch-Belgian pediatric acute myeloid leukemia protocol for children with newly diagnosed acute myeloid leukemie (DB AML-01)

Barbara De MoerlooseESJM de Bont

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Weblogs of parents with a child treated for cancer: their intentions and experiences

VERONIQUE VAN DE VELDEIlse DemaresPatricia De VosJOHAN DE PORREBarbara De MoerlooseYves BenoitGino Verleye

2009

A fatal myceliophthora thermophila infection in a child with acute myeloid leukaemia

Anne PietteBarbara De MoerlooseVeerle MondelaersPetra SchelstraeteThierry De BaereGerda VerschraegenGeert Claeys

Aberrant DNA Methylation characterizes a subtype of juvenile myelomonocytic leukemia (JMML) with poor outcome

C BatzI SandrockP NöllkeB StrahmH HasleM ZeccaJ StaryE BergsträsserBarbara De MoerlooseM Trebo et al.

CLINICAL PHARMACY ACTIVITIES AT A PEDIATRIC HEMATO-ONCOLOGY UNIT

Tieneke BautersJORIS VERLOOYJOHAN DE PORREBarbara De MoerlooseYves BenoitHugo Robays

Clinical pharmacy activities at a Pediatric Hemato-Oncology Unit

Tieneke BautersJORIS VERLOOYJOHAN DE PORREBarbara De MoerlooseYves BenoitHugo Robays

Is the risk of developing AML or MDS increased in X-linked neutropenia

K BeelM CotterJ BlatnyC ChatelainA UyttebroeckBarbara De MoerlooseNadine Van RoyG. VerhoefH DemuynckP Vandenberghe

MICRORNA SIGNATURES IN GENETIC SUBTYPES OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

Joni Van der MeulenPieter Van VlierberghePieter MestdaghJo VandesompeleBruce PoppeNadine Van RoyTom TaghonJean PlumB. CauwelierDLD Selleslag et al.

Mutational Screening in refractory cytopenia - in search of underlying SDS.

A. KarowM. FliegaufE. BergsträsserH. HasleM. Van Den Heuvel-EibrinkF. LocatelliS. Matthes-MartinBarbara De MoerlooseJ. StaryD. Wójcik et al.

Myelodysplastic syndromes in adolescents: characteristics and clinical outcome

Marco ZeccaPeter NoellkeEva BergsträßerBarbara De MoerlooseHenrik HasleSusanne Matthes-MartinLaura SainatiJan StaryBrigitte StrahmMarry M. Van Den Heuvel-Eibrink et al.

Myelodysplastisch syndroom en juveniele myelomonocytaire leukemie bij kinderen

A de VriesBarbara De MoerlooseE van WeringM van den Heuvel-Eibrink

A4 Journal Article in NEDERLANDS TIJDSCHRIFT VOOR HEMATOLOGIE

Role of the inhibitory KIR ligand HLA-Bw4 and HLA-C expression levels in the recognition of leukemic cells by Natural Killer cells.

Sonja VerheydenSoldano FerroneArend MulderFrans ClaasRik SchotsBarbara De MoerlooseYves BenoitChristian Demanet

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

2008

Evaluation of nutritional support in children undergoing haematopoietic stem cell transplantation: a single-centre experience

Sophie Van LanckerMaria Bordon Cueto De BraemJOHAN DE PORREBarbara De MoerlooseEls VandecruysJORIS VERLOOYGenevieve LaureysCatharina DhoogeYves Benoit

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

An De WeerFranki SpelemanBarbara CauwelierNadine Van RoyNurten YigitBruno VerhasseltBarbara De MoerlooseYves BenoitLucien NoensDominik Selleslag et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

Improved outcome with pulses of Vincristine (VCR) and Steroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and Non Hodgkin Lymphoma (NHL): final report of the EORTC randomized phase III trial 58951

Barbara De MoerlooseS. SuciuY. BertrandF. MazingueA. RobertA. UyttebroeckK. YacoubenA. FersterG. MargueritteP. Lutz et al.

Invasive fungal infection after allogeneic stem cell transplantation in a pediatric population: single center retrospective analysis.

Maria Bordon Cueto De BraemVeerle MondelaersBarbara De MoerlooseEls VandecruysJORIS VERLOOYYves BenoitGenevieve LaureysCatharina Dhooge

MicroRNA signatures in genetic subtypes of T-cell acute lymphoblastic leukemia.

Pieter Van VlierbergheBruce PoppeNadine Van RoyTom TaghonJean PlumB CauwelierD SelleslagP HeimannP VandenbergheN Dastugue et al.

Minimal residual disease detection at day 35 in childhood acute lymphoblastic leukemia: Which technique(s) to use?

Katrien SwertsBarbara De MoerlooseB DENYSM BAKKUSBruno VerhasseltYves BenoitJan Philippé

Retrospective evaluation of EBV viremia after pediatric allogeneic hematopoietic stem cell transplantation: single-centre experience.

Maria Bordon Cueto De BraemE PadalkoEls VandecruysJORIS VERLOOYBarbara De MoerlooseVeerle MondelaersYves BenoitGenevieve LaureysCatharina Dhooge

Surveillance of cytomegalovirus (CMV) DNAemia in pediatric allogeneic stem cell transplantation : incidence and outcome of CMV infection and disease

Maria Bordon Cueto De BraemS BravoL Van RenterghemBarbara De MoerlooseYves BenoitGenevieve LaureysCatharina Dhooge

A1 Journal Article in TRANSPLANT INFECTIOUS DISEASE

Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.

Barbara De MoerlooseKatrien SwertsM BAKKUSA UYTTEBROECKN BOECKXP VANDENBERGHEBruno VerhasseltA VAN DAMMEC DEMANETJan Philippé et al.

Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.

Barbara De MoerlooseKatrien SwertsM BakkusA UyttebroeckN BoeckxP VandenbergheBruno VerhasseltA Van DammeC DemanetYves Benoit et al.

2007

Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCR β-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique

Barbara CauwelierH CavéC GervaisM LessardC BarinC PerotJ Van den AkkerF MugneretC CharrinMP Pagès et al.

A1 Journal Article in LEUKEMIA

Het project "Koester": een uniek zorgaanbod voor kinderen met een levensbedreigende aandoening

Yves BenoitGenevieve LaureysMARIE-JEANNE DE CLERCQA VAN PUYVELDEKRISTIN MATTHEEUWSROSA VAN BOXSTAELCatharina DhoogeP DEVOSJEANNINE SYMOENSNathalie Nolf et al.

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Invasive fungal infections and allogenic stem cell transplantation in children: a single-center retrospective study

Veerle MondelaersMaria Bordon Cueto De BraemBarbara De MoerlooseEls VandecruysJORIS VERLOOYCatharina DhoogeGenevieve LaureysYves Benoit

Leukemie bij kinderen in de spotlights; verslag van de 18th Annual Meeting of the International BFM Study Group

Barbara De Moerloose

Pediatric Hematopoietic Stem Cell Transplantation: 5 years evaluation.

Maria Bordon Cueto De BraemEls VandecruysBarbara De MoerlooseJORIS VERLOOYCatharina DhoogeGenevieve LaureysYves Benoit

Prognostic value of BCL2L13 expression in childhood B-cell acute lymphoblastic leukaemia

Katrien SwertsBarbara De MoerlooseCatharina DhoogeYves BenoitJan Philippé

2006

Extramedullary relapse after hematopoietic stem cell transplant for acute leukemia in children : 'sanctuary' sites for chemotherapy and unaccessible for graft versus leukemia effect?

Genevieve LaureysT RadonicMaria Bordon Cueto De BraemBarbara De MoerlooseEls VandecruysCatharina DhoogeYves Benoit

Potential application of ELAVL4 real-time quantitative reverse transcription-PCR for detection of disseminated neuroblastoma cells

Katrien SwertsBarbara De MoerlooseCatharina DhoogeJo VandesompeleC HOYOUXK BEISKEYves BenoitGenevieve LaureysJan Philippé

A1 Journal Article in CLINICAL CHEMISTRY

Prognostic significance of blasts with/without pleiocytosis in the cerebro-spinal fluid (CSF) of children with acute lymphoblastic leukemia (ALL) treated without cranial irradiation: results of European Organization for Research and Treatment of Cancer (EORTC) children leukemia group study 58881

N SirventS SuciuX RiallandA RobertF MazingueF MillotBarbara De MoerlooseA FersterP RohrlichL Norton et al.

Prognostic significance of multidrug resistance-related proteins in childhood acute lymphoblastic leukaemia

Katrien SwertsBarbara De MoerlooseCatharina DhoogeGenevieve LaureysYves BenoitJan Philippé

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Quality of life and personality aspects of parents and siblings following the death of a child from cancer

Patricia De VosJORIS VERLOOYBarbara De MoerlooseElke De BruyneW VerdicktFilip De FruytBarbara De Clercq

Recurrent t(3;17) translocations in AML with EVII rearrangement.

A De WeerBruce PoppeB CauwelierNadine Van RoyN DastugueBarbara De MoerlooseYves BenoitLucien NoensAnne De PaepeFranki Speleman

Recurrent T(3;17)translocations in AML with EVI1 rearrangement

An De WeerBruce PoppeB CauwelierNadine Van RoyN DASTUGUEBarbara De MoerlooseYves BenoitLucien NoensAnne De PaepeFranki Speleman

The TCRB-HOXA rearrangement in T-ALL leads to a specific increase of the alternative HOXA10b transcript

B CauwelierH CAVÉN DASTUGUEP HEIMANNH ANTOINE-POIRELBruno VerhasseltYves BenoitBarbara De MoerlooseNadine Van RoyA HAGEMEIJER et al.

Therapeutic efficacy and safety of transfusion of pathogen-inactivated platelets tot pediatric patients

Inge Van hauteYves BenoitMaria Bordon Cueto De BraemBarbara De MoerlooseEls VandecruysSophie Van LanckerMURIEL VAN VOORENBart Vandekerckhove

Transiënte erythroblastopenie bij kinderen

Veerle MondelaersKATHLEEN HUNNINCKL OosterlynckJOKE VANDUYNSLAGERYves BenoitBarbara De Moerloose

A2 Journal Article in Tijdschrift voor Geneeskunde

2005

A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

Franki SpelemanBarbara CauwelierN DASTUGUEJ COOLSBruno VerhasseltBruce PoppeNadine Van RoyJo VandesompeleC GRAUXA UYTTEBROECK et al.

A1 Journal Article in LEUKEMIA

Detectie van minimale residuele ziekte bij kinderen met neuroblastoom

Barbara De MoerlooseKatrien Swerts

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

Extramedullary relapse in patients treated by donor lymphocyte infusion for haematological relapse after allogeneic bone marrow transplant

Maria Bordon Cueto De BraemBarbara De MoerlooseEls VandecruysCatharina DhoogeYves BenoitGenevieve Laureys

Het prognostisch belang van P-glycoproteïne bij kinderen met acute lymfoblasten leukemie en neuroblastomen

Barbara De Moerloose

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

HOYA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS

Bruce PoppeNurten YigitBarbara De MoerlooseAnne De PaepeYves BenoitFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Invasive fungal infections after allogeneic stem cell transplantation in children: A single-center retrospective study

Maria Bordon Cueto De BraemBarbara De MoerlooseCatharina DhoogeEls VandecruysGenevieve LaureysYves Benoit

Loodintoxicatie als gevolg van Pica

A VERSCHELDEBarbara De MoerlooseDirk Matthys

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2004

Comparison of two functional flow cytometric assays to assess P-gp activity in acute leukemia

Katrien SwertsBarbara De MoerlooseCatharina DhoogeLucien NoensGenevieve LaureysYves BenoitJan Philippé

A1 Journal Article in LEUKEMIA & LYMPHOMA

Detection of residual neuroblastoma cells in bone marrow: Comparison of flow cytometry with immunocytochemistry

K SWERTSBarbara De MoerlooseCatharina DhoogeB BRICHARDYves BenoitGenevieve LaureysJan Philippé

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Four-color flow cytometric detection of residual neuroblastoma cells

Jan PhilippéKatrien SwertsBarbara De MoerlooseCatharina DhoogeYves BenoitGenevieve Laureys

2003

Actuele inzichten en prognostische karakteristieken van het neuroblastoom

Barbara De MoerlooseKatrien SwertsGenevieve Laureys

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

CNS relapse in a stage 3 neuroblastoma patient

Barbara De MoerlooseVALERIE MEERSSCHAUTYves BenoitGenevieve Laureys

The combined analysis of P-glycoprotein expression and activity predicts outcome in childhood acute lymphoblastic leukemia

Barbara De MoerlooseKatrien SwertsYves BenoitGenevieve LaureysTom LoeysJan PhilippéCatharina Dhooge

A1 Journal Article in PEDIATRIC HEMATOLOGY AND ONCOLOGY

The quantification of MDR1 transcripts by real-time RT-PCR does not predict drug resistance in childhood acute lymphoblastic leukemia

Katrien SwertsBarbara De MoerlooseB LEUSCatharina DhoogeGenevieve LaureysBruno VerhasseltYves BenoitJan Philippé

2002

Expression of the multidrug transporter P-glycoprotein is highly correlated with clinical outcome in childhood acute lymphoblastic leukemia: Results of a long-term prospective study.

Catharina DhoogeBarbara De MoerlooseGenevieve LaureysA FERSTERDirk De BacquerJan PhilippéJuliaan LeroyYves Benoit

A1 Journal Article in LEUKEMIA & LYMPHOMA

2001

Combined evaluation of P-glycoprotein expression and activity contributes to the identification of children at risk for leukaemic relapse

Barbara De MoerlooseKatrien SwertsCatharina DhoogeS STEYAERTYves BenoitGenevieve LaureysJan Philippé

2000

Repetitive analyses of P-glycoprotein in chronic myeloid leukaemia

Barbara De MoerlooseA MuylaertF GemmelAnne JanssensBruce PoppeCatharina DhoogeWerner Van HoveJan Philippé

A1 Journal Article in ACTA CLINICA BELGICA

1999

Chromosome 7 short arm deletions and disease progression in CML

Bruce PoppeH VAN LIMBERGENANN JANSSENSNadine Van RoyBarbara De MoerlooseJ PHILLIPEAnne De PaepeFritz OffnerFranki Speleman

Discrepant flow cytometric expression and function of P-glycoprotein in neuroblastic tumors

Barbara De MoerlooseCatharina DhoogeGenevieve LaureysYves BenoitM DEMARCHEC DEVALCKD PLANTAZJuliaan LeroyJan Philippé

A1 Journal Article in CYTOMETRY

P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia : results of a 6-year prospective study

Catharina DhoogeBarbara De MoerlooseGenevieve LaureysJozef KintA FersterDirk De BacquerJan PhilippéYves Benoit

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

P-Glycoproteine in de aanpak van chemotherapieresistentie.

Barbara De MoerlooseCatharina DhoogeJ PHILIPPEYves BenoitJozef KintJuliaan Leroy

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Technetium-99m sestamibi imaging in paediatric neuroblastoma and ganglioneuroma and its relation to P-glycoprotein.

Barbara De MoerlooseC VAN DE WIELECatharina DhoogeJan PhilippéFranki SpelemanYves BenoitGenevieve LaureysRudi Dierckx

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE

1997

Expression of the MDR1 gene product P-glycoprotein in childhood neuroblastoma

Catharina DhoogeBarbara De MoerlooseYves BenoitNadine Van RoyJan PhilippéGenevieve Laureys

A1 Journal Article in CANCER

1996

Immunocytochemical and flow cytometric analysis of P-glycoprotein in childhood ALL

Barbara De MoerlooseJan PhilippéCatharina Dhooge

1994

Expression of the multidrug transporter, P-glycoprotein, in childhood leukemia: a prospective clinical study

Catharina DhoogeBarbara De MoerlooseC De PotterGenevieve LaureysYves BenoitJ Leroy

A2 Journal Article in INTERNATIONAL JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY