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Researcher
Barbara De Moerloose
Profile
Projects
Publications & Research Data
Activities
Awards & Distinctions
Patents
312
Results
2025
Exploring germline variants in genes associated with inborn errors of immunity and inherited bone marrow failure syndromes in pediatric hematological malignancies
Jette J. Bakhuizen
Freerk van Dijk
Sebastian B.B. Bon
Lars T. van der Veken
Manon M.H. Huibers
Joris M. van Montfrans
Marieke De Bruyne
Barbara De Moerloose
Filomeen Haerynck
Jan L.C. Loeffen
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF CANCER
2025
Involvement of THBS1 in myeloid sarcoma of acute myeloid leukemia
Zhiyao Ren
Jolien Vanhooren
Barbara De Moerloose
Tim Lammens
Editorial material
2025
Management of children and adolescents with chronic myeloid leukemia in chronic phase : international pediatric chronic myeloid leukemia expert panel recommendations
Frédéric Millot
Mirella Ampatzidou
Nirmalya Roy Moulik
Sanjay Tewari
Alaa Elhaddad
Mahmoud Hammad
Herbert Pichler
Thomas Lion
Athanasios Tragiannidis
Haruko Shima
et al.
A1
Journal Article
in
LEUKEMIA
2025
Nidogen-1, a player in KMT2A-rearranged pediatric acute myeloid leukemia
Jolien Vanhooren
Larissa Deneweth
Luca Pagliaro
Zhiyao Ren
Mariateresa Giaimo
Rafaella Zamponi
Giovanni Roti
Barbara Depreter
Mattias Hofmans
Barbara De Moerloose
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2025
Prime-time for IncRNA signatures in acute myeloid leukaemia?
Z Ren
Barbara De Moerloose
Tim Lammens
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2025
Prime-time for LncRNA signatures in acute myeloid leukemia?
Zhiyao Ren
Barbara De Moerloose
Tim Lammens
A1
Journal Article
in
ANNALS OF HEMATOLOGY
2025
Profiling histone post-translational modifications to identify signatures of epigenetic drug response in T-cell acute lymphoblastic leukemia
Laura Corveleyn
Lien Provez
Osman Satilmis
Nina Refhagen
Mattias Landfors
Wouter Sleeckx
Béatrice Lintermans
Amélie De Maesschalck
Rishi S. Kotecha
Barbara De Moerloose
et al.
Preprint
2025
Project EVOLVE : an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia
Sara K. Silbert
Alexander W. Rankin
Chloe N. Hoang
Alexandra Semchenkova
Regina M. Myers
Elena Zerkalenkova
Hao-Wei Wang
Alexandra E. Kovach
Constance M. Yuan
Dana Delgado Colon
et al.
A1
Journal Article
in
BLOOD
2025
The role of UBTF-TD mutations in paediatric acute myeloid leukaemia and myelodysplastic syndrome
B Decuyper
I Andriessen
Mattias Hofmans
Barbara De Moerloose
[0-9]{2}
2025
2024
A 69 long non-coding RNAs expression signature predicts relapse and acts as an independent prognostic factor in pediatric acute myeloid leukemia
Zhiyao Ren
Jolien Vanhooren
Charlotte Derpoorter
Barbara De Moerloose
Tim Lammens
C3
Conference
2024
A 69 long noncoding RNA signature predicts relapse and acts as independent prognostic factor in pediatric AML
Zhiyao Ren
Jolien Vanhooren
Charlotte Derpoorter
Barbara De Moerloose
Tim Lammens
A1
Journal Article
in
BLOOD ADVANCES
2024
Characterization of pediatric acute myeloid leukemia with t(7;12)(q36;p13)
Anders Östlund
Ahmed Waraky
Anna Staffas
Helene Sjögren
Barbara De Moerloose
Nira Arad‐Cohen
Daniel Cheuk
Jose Maria Fernandez Navarro
Kirsi Jahnukainen
Gertjan J. L. Kaspers
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2024
Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis : results from the NOPHO-DBH AML 2012 protocol
Bernward Zeller
Nira Arad-Cohen
Daniel Cheuk
Barbara De Moerloose
Jose M Fernandez Navarro
Henrik Hasle
Kirsi Jahnukainen
Kristian Lovvik Juul-Dam
Gertjan Kaspers
Zanna Kovalova
et al.
A1
Journal Article
in
HAEMATOLOGICA
2024
Mitoxantrone versus liposomal daunorubicin in induction of pediatric AML with risk stratification based on flow cytometry measurement of residual disease
Anne Tierens
Nira Arad-Cohen
Daniel Cheuk
Barbara De Moerloose
Jose Maria Fernandez Navarro
Henrik Hasle
Kirsi Jahnukainen
Kristian Løvvik Juul-Dam
Gertjan Kaspers
Zanna Kovalova
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2024
Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia
André Pedro Pinto De Almeida
Sara T'Sas
Luca Pagliaro
Igor Fijalkowski
Wouter Sleeckx
Hannah Van Steenberge
Raffaella Zamponi
Béatrice Lintermans
Wouter Van Loocke
Bruno Palhais
et al.
A1
Journal Article
in
HEMASPHERE
2024
Nidogen-1, a novel player in KMT2A-rearranged pediatric acute myeloid leukemia patients, expressed in the leukemic stem cell
Jolien Vanhooren
Larissa Deneweth
Luca Pagliaro
Zhiyao Ren
Barbara Depreter
Mattias Hofmans
Barbara De Moerloose
Tim Lammens
C3
Conference
2024
Precision medicine in relapsed and refractory paediatric haematological malignancies and the role of an international tumour board
Alexandra Reekmans
Uri Ilan
Judith M Boer
Tim Lammens
Steven Goossens
C Michel Zwaan
Monique L den Boer
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2024
Results of the prospective EORTC Children Leukemia Group study 58081 in precursor B‐ and T‐cell acute lymphoblastic leukemia
Carine Domenech
Michal Kicinski
Barbara De Moerloose
Caroline Piette
Wadih A. Chahla
Laure Kornreich
Marlène Pasquet
Anne Uyttebroeck
Alexandre Theron
Marilyne Poirée
et al.
A1
Journal Article
in
HEMASPHERE
2024
Spontaneous remission and loss of monosomy 7 : a window of opportunity for young children with SAMD9L syndrome
Miriam Erlacher
Felicia Andresen
Martina Sukova
Jan Stary
Barbara De Moerloose
Jutte van der Werff Ten Bosch
Michael Dworzak
Markus G. Seidel
Sophia Polychronopoulou
Rita Beier
et al.
A1
Journal Article
in
HAEMATOLOGICA
2024
Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma
Stien De Coninck
Renate De Smedt
Béatrice Lintermans
Lindy Reunes
Hansen J. Kosasih
Alexandra Reekmans
Lauren M. Brown
Nadine Van Roy
Bruno Palhais
Juliette Roels
et al.
A1
Journal Article
in
HAEMATOLOGICA
2024
Ultra-deep sequencing and single cell multi-omics characterize measurable residual disease and identify therapy-survived clone in pediatric acute myeloid leukemia
Borhan R. R Saeed
Anastasia Saboli
Anna Rehammar
Adam Molnar
Erik Delsing Malmberg
Barbara Depreter
Giti Shah Barkhordar
Barbara De Moerloose
Tim Lammens
Lars Palmqvist
et al.
C3
Conference
2024
2023
A 46 long non-coding RNAs expression signature accurately predicts relapse and acts as an independent prognostic factor in pediatric acute myeloid leukemia
Zhiyao Ren
Jolien Vanhooren
Charlotte Derpoorter
Barbara De Moerloose
Tim Lammens
C3
Conference
2023
CAR-T in the treatment of acute myeloid leukemia : barriers and how to overcome them
Jolien Vanhooren
Rani Dobbelaere
Charlotte Derpoorter
Larissa Deneweth
Laurens Van Camp
Anne Uyttebroeck
Barbara De Moerloose
Tim Lammens
A1
Journal Article
in
HEMASPHERE
2023
Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia
Lene Karlsson
Daniel Cheuk
Barbara De Moerloose
Henrik Hasle
Kirsi Jahnukainen
Kristian Løvvik Juul‐Dam
Gertjan Kaspers
Zanna Kovalova
Birgitte Lausen
Ulrika Norén Nyström
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2023
Drug response profiling informs personalized bridging to cell therapy for patients with relapsed/refractory acute lymphoblastic leukemia
Fabio D. Steffen
Andrej Lissat
Julia Alten
Cornelia Eckert
Bodmer Nicole
Thorhauge Als-Nielsen Bodil E.
Adriana Balduzzi
Sarah Elitzur
Andras Kriston
Gergely Nyiri
et al.
C3
Conference
2023
In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia
Maaike Van Trimpont
Amanda M. Schalk
Yanti De Visser
Hien Anh Nguyen
Lindy Reunes
Katrien Vandemeulebroecke
Evelien Peeters
Ying Su
Hyun Lee
Philip L. Lorenzi
et al.
A1
Journal Article
in
HAEMATOLOGICA
2023
Management of children and adolescents with chronic myeloid leukemia in blast phase : international pediatric CML expert panel recommendations
Stephanie Sembill
Maria Ampatzidou
Sonali Chaudhury
Michael Dworzak
Krzysztof Kalwak
Axel Karow
Alexander Kiani
Manuela Krumbholz
Maaike Luesink
Nora Naumann-Bartsch
et al.
A1
Journal Article
in
LEUKEMIA
2023
Measurable residual disease and fusion partner independently predict survival and relapse risk in childhood KMT2A-rearranged acute myeloid leukemia : a study by the International Berlin-Frankfurt-Münster Study Group
Romy E. van Weelderen
Kim Klein
Christine J. Harrison
Yilin Jiang
Jonas Abrahamsson
Nira Arad-Cohen
Emmanuelle Bart-Delabesse
Barbara Buldini
Barbara De Moerloose
Michael N. Dworzak
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2023
Outcome of chimeric antigen receptor T-cell therapy following treatment with inotuzumab ozogamicin in children with relapsed or refractory acute lymphoblastic leukemia
Valeria Ceolin
Erica Brivio
Harm van Tinteren
Susan R. Rheingold
Allison Leahy
Britta Vormoor
Maureen M. O’Brien
Jeremy D. Rubinstein
Krzysztof Kalwak
Barbara De Moerloose
et al.
A1
Journal Article
in
LEUKEMIA
2023
Outcomes of childhood noninfant acute lymphoblastic leukemia with 11q23/KMT2A rearrangements in a modern therapy era : a retrospective international study
Andishe Attarbaschi
Anja Möricke
Christine J. Harrison
Georg Mann
André Baruchel
Barbara De Moerloose
Valentino Conter
Meenakshi Devidas
Sarah Elitzur
Gabriele Escherich
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2023
Retrospective study of children with chronic myeloid leukemia treated in Belgium between 2000 and 2021
Klaartje Van Schelvergem
Laurens Van Camp
Veerle Labarque
Laure Kornreich
Koen Norga
Barbara De Moerloose
C3
Conference
2023
The clinical spectrum and biological findings in RAS-associated juvenile myelomonocytic leukemia and RAS-associated autoimmune leukoproliferative disorder
Hanne Verhulst
Laurens Van Camp
Mattias Hofmans
Barbara De Moerloose
C3
Conference
2023
The prognostic value of IKZF1(plus) in B‐cell progenitor acute lymphoblastic leukemia : results from the EORTC 58951 trial
Michal Kicinski
Chloé Arfeuille
Nathalie Grardel
Marleen Bakkus
Aurélie Caye‐Eude
Geneviève Plat
Alina Ferster
Anne Uyttebroeck
Barbara De Moerloose
Pierre Rohrlich
et al.
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2023
2022
Brachytherapy for pediatric patients at Gustave Roussy Cancer Campus : a model of international cooperation for highly specialized treatments
Cyrus Chargari
Christine Haie-Meder
Sophie Espenel
Max-Adrien Garcia
Myriam Ben-Arush
Stéphanie Bolle
Anna Borjesson
Maja Cesen
Rita Costa Lago
Anne-Sophie Defachelles
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
2022
Clinical outcomes of second relapsed and refractory first relapsed paediatric AML : a retrospective study within the NOPHO‐DB SHIP consortium
Tara White
Gertjan Kaspers
Jonas Abrahamsson
Nira Arad‐Cohen
Daniela Cianci
Jose Fernandez
Shau‐Yin Ha
Henrik Hasle
Barbara De Moerloose
C. Michel Zwaan
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2022
Deciphering the non-coding landscape of pediatric acute myeloid leukemia
Laurens Van Camp
Jolien Vanhooren
Barbara Depreter
Martijn de Jong
Anne Uyttebroeck
An Van Damme
Laurence Dedeken
Marie-Françoise Dresse
Jutte van der Werff ten Bosch
Mattias Hofmans
et al.
C3
Conference
2022
Deciphering the non-coding landscape of pediatric acute myeloid leukemia
Jolien Vanhooren
Laurens Van Camp
Barbara Depreter
Martijn de Jong
Anne Uyttebroeck
An Van Damme
Laurence Dedeken
Marie-Françoise Dresse
Jutte van der Werff ten Bosch
Mattias Hofmans
et al.
C3
Conference
2022
Deciphering the non-coding RNA landscape of pediatric acute myeloid leukemia
Jolien Vanhooren
Laurens Van Camp
Barbara Depreter
Martijn de Jong
Anne Uyttebroeck
An Van Van Damme
Laurence Dedeken
Marie-Françoise Dresse
Jutte van der Werff ten Bosch
Mattias Hofmans
et al.
A1
Journal Article
in
CANCERS
2022
Familial hemophagocytic lymphohistiocytosis type 3 presenting as neonatal cholestasis and splenomegaly
Delfien Bogaert
Ruth De Bruyne
Arnaud Vanlander
Lara Garabedian
Yves Louis
Filomeen Haerynck
Victoria Bordon
Barbara De Moerloose
A1
Journal Article
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2022
Guideline for management of non-Down syndrome neonates with a myeloproliferative disease on behalf of the I-BMF AML Study Group and EWOG-MDS
E Bertrums
CM Zwaan
D Hasegawa
V de Haas
DN Reinhardt
F Locatelli
Barbara De Moerloose
M Dworzak
A Buijs
P Smisek
et al.
A1
Journal Article
in
HAEMATOLOGICA
2022
Immunoglobulin heavy chain high-throughput sequencing in pediatric B-precursor acute lymphoblastic leukemia : is the clonality of the disease at diagnosis related to its prognosis?
Gabriel Levy
Michal Kicinski
Jona Van der Straeten
Anne Uyttebroeck
Alina Ferster
Barbara De Moerloose
Marie-Francoise Dresse
Christophe Chantrain
Bénédicte Brichard
Marleen Bakkus
A1
Journal Article
in
FRONTIERS IN PEDIATRICS
2022
Mutational permutations of a single amino acid exert divergent phenotypic effects in human, mice and cellular models of SAMD9L bone marrow failure disorder
Sushree S Sahoo
Charnise Goodings-Harris
Shondra Miller
Maria Angeles Lillo Osuna
Baranda S Hansen
Lei Han
Ti-Cheng Chang
Tim Lammens
Mattias Hofmans
Marta Derecka
et al.
C3
Conference
2022
Novel insights on the use of L-asparaginase as an efficient and safe anti-cancer therapy
Maaike Van Trimpont
Evelien Peeters
Yanti De Visser
Amanda M. Schalk
Veerle Mondelaers
Barbara De Moerloose
Arnon Lavie
Tim Lammens
Steven Goossens
Pieter Van Vlierberghe
A1
Journal Article
in
CANCERS
2022
Optimization of asparaginase therapy in childhood acute lymphoblastic leukemia
Veerle Mondelaers
Barbara De Moerloose
Tim Lammens
Dissertation
2022
Practice guidelines for the therapeutic drug monitoring of asparaginase in acute lymphoblastic leukemia
Veerle Mondelaers
Tim Lammens
Martijn de Jong
Larissa Deneweth
Katrien Vandemeulebroecke
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2022
Supportive care in pediatric acute myeloid leukemia : expert-based recommendations of the NOPHO-DB-SHIP consortium
Nira Arad-Cohen
Bernward Zeller
Jonas Abrahamsson
Jose Maria Fernandez Navarro
Daniel Cheuk
Sauli Palmu
Vitor Costa
Barbara De Moerloose
Henrik Hasle
Kirsi Jahnukainen
et al.
A1
Journal Article
in
EXPERT REVIEW OF ANTICANCER THERAPY
2022
Targeted therapy in juvenile myelomonocytic leukemia : where are we now?
Nele De Vos
Mattias Hofmans
Tim Lammens
Bram De Wilde
Nadine Van Roy
Barbara De Moerloose
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2022
TEARDRoP Oncology : BBRMI.be workshop on sustainability
Liselot Mus
Bram De Wilde
Catherine Van Der Straeten
Barbara De Moerloose
Sandra Jacobs
Sylvie Rottey
Marie-Francoise Dresse
Ilse De Reze
C3
Conference
2022
TEARDRoP oncology : good practices for paediatric biobanking
Liselot Mus
Bram De Wilde
Catherine Van Der Straeten
Barbara De Moerloose
Sandra Jacobs
Sylvie Rottey
Marie-Francoise Dresse
Ilse De Reze
C3
Conference
2022
The TEARDRoP (Team early drug development in Paediatric oncology) consortium : to help Research find its way to improved treatments for children with cancer
Liselot Mus
Bram De Wilde
Catherine Van Der Straeten
Barbara De Moerloose
Sandra Jacobs
Sylvie Rottey
Marie-Francoise Dresse
Ilse De Reze
C3
Conference
2022
Three-year update of tisagenlecleucel in pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia in the ELIANA trial
Theodore W. Laetsch
Shannon L. Maude
Susana Rives
Hidefumi Hiramatsu
Henrique Bittencourt
Peter Bader
André Baruchel
Michael Boyer
Barbara De Moerloose
Muna Qayed
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2022
Tisagenlecleucel therapy for relapsed or refractory B-cell acute lymphoblastic leukaemia in infants and children younger than 3 years of age at screening : an international, multicentre, retrospective cohort study
Sara Ghorashian
Elad Jacoby
Barbara De Moerloose
Susana Rives
Denise Bonney
Geoff Shenton
Peter Bader
Nicole Bodmer
Agueda Molinos Quintana
Blanca Herrero
et al.
A1
Journal Article
in
LANCET HAEMATOLOGY
2022
2021
CAR-T treatment of pediatric AML : a long and winding road
Barbara De Moerloose
Editorial material
2021
CircRNAs dysregulated in juvenile myelomonocytic leukemia : CircMCTP1 stands out
Anna Dal Molin
Mattias Hofmans
Enrico Gaffo
Alessia Buratin
Hélène Cavé
Christian Flotho
Valerie de Haas
Charlotte M. Niemeyer
Jan Stary
Pieter Van Vlierberghe
et al.
A1
Journal Article
in
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021
Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes
Sushree S. Sahoo
Victor B. Pastor
Charnise Goodings
Rebecca K. Voss
Emilia J. Kozyra
Amina Szvetnik
Peter Noellke
Michael Dworzak
Jan Stary
Franco Locatelli
et al.
A1
Journal Article
in
NATURE MEDICINE
2021
CNS-3 status remains an independent adverse prognosis factor in children with acute lymphoblastic leukemia (ALL) treated without cranial irradiation : results of EORTC Children Leukemia Group study 58951
N. Sirvent
S. Suciu
Barbara De Moerloose
A. Ferster
F. Mazingue
G. Plat
K. Yakouben
A. Uyttebroeck
C. Paillard
V Costa
et al.
A1
Journal Article
in
ARCHIVES DE PEDIATRIE
2021
Current developments and hurdles in CAR-T cell therapy for acute myeloid leukaemia
Laurens Van Camp
Tim Lammens
Anne Uyttebroeck
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2021
Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach
Barbara Depreter
Barbara De Moerloose
Karl Vandepoele
Anne Uyttebroeck
An Van Damme
Eva Terras
Barbara Denys
Laurence Dedeken
Marie-Francoise Dresse
Jutte Van der Werff Ten Bosch
et al.
A1
Journal Article
in
PEDIATRIC RESEARCH
2021
Features and outcome of chronic myeloid leukemia at very young age : data from the International Pediatric Chronic Myeloid Leukemia Registry
Adalet Meral Gunes
Frederic Millot
Krzysztof Kalwak
Birgitte Lausen
Petr Sedlacek
A. Birgitta Versluys
Michael Dworzak
Barbara De Moerloose
Meinolf Suttorp
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2021
Germline SAMD9L triple-allelic mosaicism with independent segregation into biallelic offsprings : molecular support for non-mendelian inheritance
S Sahoo
C Goodings
M Angeles Lillo
Tim Lammens
J van der Werff ten Bosch
B Strahm
Barbara De Moerloose
M Wlodarski
C3
Conference
2021
Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome
Rachel Bortnick
Marcin Wlodarski
Valerie de Haas
Barbara De Moerloose
Michael Dworzak
Henrik Hasle
Riccardo Masetti
Jan Starý
Dominik Turkiewicz
Marek Ussowicz
et al.
A1
Journal Article
in
BONE MARROW TRANSPLANTATION
2021
Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia
Mattias Hofmans
Tim Lammens
Barbara Depreter
Ying Wu
Miriam Erlacher
Aurélie Caye
Hélène Cavé
Christian Flotho
Valerie de Haas
Charlotte M. Niemeyer
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2021
Novel therapeutic targets in juvenile myelomonocytic leukaemia : are noncoding RNAs valuable treatment options?
Mattias Hofmans
Tim Lammens
Jan Philippé
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2021
Novel therapeutic targets in juvenile myelomonocytic leukemia : are noncoding RNAs valuable treatment options?
Mattias Hofmans
Barbara De Moerloose
Jan Philippé
Tim Lammens
Dissertation
2021
Parental experience and emotional well-being in families with a child with a chronic disease during the COVID 19 pandemic
Eline Van Hoecke
Karlien Dhondt
Ann Raes
Stephanie Van Biervliet
Barbara De Moerloose
Sara Van Aken
Filomeen Haerynck
Levi Hoste
Helene Verhelst
Bart Soenens
et al.
C3
Conference
2021
Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia
John E Levine
Stephan A Grupp
Michael A Pulsipher
Andrew C Dietz
Susana Rives
G Douglas Myers
Keith J August
Michael R Verneris
Jochen Buechner
Theodore W Laetsch
et al.
A1
Journal Article
in
JOURNAL FOR IMMUNOTHERAPY OF CANCER
2021
Practical guidelines for monitoring and management of coagulopathy following tisagenlecleucel CAR T-cell therapy
Jochen Buechner
Stephan A. Grupp
Hidefumi Hiramatsu
David T. Teachey
Susana Rives
Theodore W. Laetsch
Gregory A. Yanik
Patricia Wood
Rakesh Awasthi
Lan Yi
et al.
A1
Journal Article
in
BLOOD ADVANCES
2021
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia
Filip Matthijssens
Nitesh D. Sharma
Monique Nysus
Christian K. Nickl
Huining Kang
Dominique R. Perez
Béatrice Lintermans
Wouter Van Loocke
Juliette Roels
Sofie Peirs
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL INVESTIGATION
2021
TARP as antigen in cancer immunotherapy
Jolien Vanhooren
Charlotte Derpoorter
Barbara Depreter
Larissa Deneweth
Jan Philippé
Barbara De Moerloose
Tim Lammens
A1
Journal Article
in
CANCER IMMUNOLOGY IMMUNOTHERAPY
2021
The variable biological signature of refractory cytopenia of childhood (RCC), a retrospective EWOG-MDS study
Demi T.C. de Winter
Anton W. Langerak
Jeroen te Marvelde
Michael N. Dworzak
Barbara De Moerloose
Jan Starý
Franco Locatelli
Henrik Hasle
Andrica C.H. de Vries
Markus Schmugge
et al.
A1
Journal Article
in
LEUKEMIA RESEARCH
2021
2020
A semi-mechanistic population pharmacokinetic/pharmacodynamic model of bortezomib in pediatric patients with relapsed/refractory acute lymphoblastic leukemia
Julie M Janssen
TPC Dorlo
D Niewerth
AJ Wilhelm
CM Zwaan
JH Beijnen
A Attarbaschi
A Baruchel
F Fagioli
T Klingebiel
et al.
A1
Journal Article
in
CLINICAL PHARMACOKINETICS
2020
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia
Juliette Roels
Morgan Thénoz
Bronislawa Szarzynska
Mattias Landfors
Stien De Coninck
Lisa Demoen
Lien Provez
Anna Kuchmiy
Steven Strubbe
Lindy Reunes
et al.
C3
Conference
2020
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia
Juliette Roels
Morgan Thénoz
B Szarzyńska
M Landfors
Stien De Coninck
Lisa Demoen
Lien Provez
Anna Kuchmiy
Steven Strubbe
Lindy Reunes
et al.
A2
Journal Article
in
BLOOD CANCER DISCOVERY
2020
Big children or small adults? Acute myeloid leukaemia (AML) treatment in adolescence and young adulthood
Karolien Maes
Barbara De Moerloose
MARIJKE QUAGHEBEUR
JOHAN DE MUNTER
Tessa Kerre
Ine Moors
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2020
Big children or small adults? Leukaemia treatment in adolescence and young adulthood
Rutger Callens
Barbara De Moerloose
Tessa Kerre
MARIJKE QUAGHEBEUR
JOHAN DE MUNTER
Ine Moors
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2020
Clinical significance of TARP expression in pediatric acute myeloid leukemia
B. Depreter
Barbara De Moerloose
Karl Vandepoele
A. Uyttebroeck
A. Van Damme
B. Denys
L. Dedeken
M. -F. Dresse
J. Van der Werff Ten Bosch
M. Hofmans
et al.
C3
Conference
2020
Clinical significance of TARP expression in pediatric acute myeloid leukemia
Barbara Depreter
Barbara De Moerloose
Karl Vandepoele
Anne Uyttebroeck
An Van Damme
Barbara Denys
Laurence Dedeken
Marie-Françoise Dresse
Jutte Van Der Werff Ten Bosch
Mattias Hofmans
et al.
A1
Journal Article
in
HEMASPHERE
2020
Leukaemic stem cells in AML : where are we now? An update on recent findings and detection
Barbara Depreter
Barbara De Moerloose
Jan Philippé
Tim Lammens
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2020
Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib : a report from the I-CML-Ped Study
Deborah Meyran
Arnaud Petit
Joelle Guilhot
Meinolf Suttorp
Petr Sedlacek
Eveline De Bont
Chi Kong Li
Krzysztof Kalwak
Brigitte Lausen
Srdjana Culic
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF CANCER
2020
Not all pediatric intestinal polyps are alike
Drieke Vermeulen
Myriam Van Winckel
Saskia Vande Velde
Ruth De Bruyne
Stephanie Van Biervliet
Barbara De Moerloose
Lucas E Matthyssens
Katrien Van Renterghem
Dirk Van de Putte
A1
Journal Article
in
ACTA GASTRO-ENTEROLOGICA BELGICA
2020
Pediatric randomized trial EORTC CLG 58951 : outcome for adolescent population with acute lymphoblastic leukemia
Laura Olivier-Gougenheim
Chloe Arfeuille
Stefan Suciu
Nicolas Sirvent
Genevieve Plat
Alina Ferster
Barbara De Moerloose
Carine Domenech
Anne Uyttebroeck
Pierre-Simon Rohrlich
et al.
A1
Journal Article
in
HEMATOLOGICAL ONCOLOGY
2020
Prospective, real-time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma in Belgium
Veerle Mondelaers
Alina Ferster
Anne Uyttebroeck
Benedicte Brichard
Juttevan der Werff ten Bosch
Koenraad Norga
Nadine Francotte
Caroline Piette
Katrien Vandemeulebroecke
Charlotte Verbeke
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2020
Retrospective analysis of the incidence and characteristics of paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia in Belgium
Lindsey De Smaele
Mattias Hofmans
Tim Lammens
A Van Damme
Jutte van der Werff ten Bosch
A Ferster
Joris Verlooy
C Chantrain
Jan Philippé
Nadine Van Roy
et al.
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2020
Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency
Emilia J. Kozyra
Victor B. Pastor
Stylianos Lefkopoulos
Sushree S. Sahoo
Hauke Busch
Rebecca K. Voss
Miriam Erlacher
Dirk Lebrecht
Enikoe A. Szvetnik
Shinsuke Hirabayashi
et al.
A1
Journal Article
in
LEUKEMIA
2020
Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma
Renate De Smedt
Julie Morscio
Lindy Reunes
Juliette Roels
Valentina Bardelli
Béatrice Lintermans
Wouter Van Loocke
Afonso Almeida
Laurence C. Cheung
Rishi S. Kotecha
et al.
A1
Journal Article
in
BLOOD
2020
TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment
Barbara Depreter
Karin Weening
Karl Vandepoele
Magnus Essand
Barbara De Moerloose
Maria Themeli
Jacqueline Cloos
Diana Hanekamp
Ine Moors
INGE D'HONT
et al.
A1
Journal Article
in
HAEMATOLOGICA
2020
The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing
L Zubovic
S Piazza
T Tebaldi
L Cozzuto
G Palazzo
V Sidarovich
V De Sanctis
R Bertorelli
Tim Lammens
Mattias Hofmans
et al.
A1
Journal Article
in
JOURNAL OF HEMATOLOGY & ONCOLOGY
2020
2019
Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia
Ditte JA Lohmann
Peter H Asdahl
Jonas Abrahamsson
Shau-Yin Ha
Olafur G Jonsson
Gertjan JL Kaspers
Minna Koskenvuo
Birgitte Lausen
Barbara De Moerloose
Josefine Palle
et al.
A1
Journal Article
in
CANCER MEDICINE
2019
Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach
Barbara Depreter
Mattias Hofmans
Eva Terras
Anne Uyttebroeck
An Van Damme
Alina Ferster
Jutte Van der Werff Ten Bosch
Marie-Françoise Dresse
Karl Vandepoele
Barbara De Moerloose
et al.
C3
Conference
2019
Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach
Barbara Depreter
Mattias Hofmans
Eva Terras
Anne Uyttebroeck
An Van Damme
Alina Ferster
Jutte van der Werff ten Bosch
Marie-Françoise Dresse
Karl Vandepoele
Barbara De Moerloose
et al.
C3
Conference
2019
Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia
Gloria Milani
Filip Matthijssens
Wouter Van Loocke
Kaat Durinck
Juliette Roels
Sofie Peirs
Morgan Thénoz
Tim Pieters
Lindy Reunes
Béatrice Lintermans
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2019
Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia : proof of concept study
Mattias Hofmans
Barbara Depreter
Tim Lammens
Helene Cave
Christian Flotho
Henrik Hasle
Valerie de Haas
Charlotte M. Niemeyer
Jan Stary
Pieter Van Vlierberghe
et al.
C3
Conference
2019
Noonan syndrome-associated myeloproliferative disorder with somatically acquired monosomy 7 : impact on clinical decision making
Mattias Hofmans
Rieke Schroeder
Tim Lammens
Christian Flotho
Charlotte Niemeyer
Nadine Van Roy
Wim Decaluwe
Jan Philippé
Barbara De Moerloose
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2019
Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia : a global, single-arm, phase 2 trial
Theodore W. Laetsch
Gary Douglas Myers
Andre Baruchel
Andrew C. Dietz
Michael A. Pulsipher
Henrique Bittencourt
Jochen Buechner
Barbara De Moerloose
Kara L. Davis
Eneida Nemecek
et al.
A1
Journal Article
in
LANCET ONCOLOGY
2019
Phase I dose‐escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors
François Doz
Franco Locatelli
André Baruchel
Nicolas Blin
Barbara De Moerloose
Didier Frappaz
Michael Dworzak
Matthias Fischer
Jan Stary
Rene Fuertig
et al.
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2019
Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01
Barbara De Moerloose
Ardine Reedijk
Geertruida H. de Bock
Tim Lammens
Valerie de Haas
Barbara Denys
Laurence Dedeken
Marry M. van den Heuvel-Eibrink
Maroeska te Loo
Anne Uyttebroeck
et al.
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2019
Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL)
Mattias Hofmans
Stefan Suciu
Alina Ferster
Pieter Van Vlierberghe
Françoise Mazingue
Nicolas Sirvent
Vitor Costa
Karima Yakouben
Catherine Paillard
Anne Uyttebroeck
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2019
TARP as immunotherapeutic target in AML expressed in the LSC compartment
Barbara Depreter
Karin Weening
Karl Vandepoele
M Essand
Barbara De Moerloose
M Themeli
J Cloos
D Hanekamp
Ine Moors
INGE D'HONT
et al.
C3
Conference
2019
The strategic plan for paediatric cancer treatment in Belgium
A Van Damme
Barbara De Moerloose
B Brichard
A Ferster
B Heenen
Genevieve Laureys
Koen Norga
C Piette
Jutte Van Der Werff Ten Bosch
Anne Uyttebroeck
A2
Journal Article
in
BELGIAN JOURNAL OF MEDICAL ONCOLOGY
2019
Use of granulocyte colony-stimulating factor and risk of relapse in pediatric patients treated for acute myeloid leukemia according to NOPHO-AML 2004 and DB AML-01
Ditte JA Lohmann
Peter H Asdahl
Jonas Abrahamsson
Shau-Yin Ha
Olafur G Jonsson
Gertjan JL Kaspers
Minna Koskenvuo
Birgitte Lausen
Barbara De Moerloose
Josefine Palle
et al.
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2019
2018
A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T- and B-cell acute lymphoblastic leukemias in vivo
Hien Anh Nguyen
Ying Su
Jenny Yu Zhang
Aleksandar Antanasijevic
Michael Caffrey
Amanda M Schalk
Li Liu
Damiano Rondelli
Annie Oh
Dolores L Mahmud
et al.
A1
Journal Article
in
CANCER RESEARCH
2018
Aandachtspunten bij een therapie met voriconazole
Franky Buyle
Katleen Van Butsele
S Mertens
Barbara De Moerloose
Dirk Vogelaers
L Van Der Linden
I Spriet
Annemie Somers
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2018
Associations between neutrophil recovery time, infections and relapse in pediatric acute myeloid leukemia
Ditte JA Løhmann
Peter H Asdahl
Jonas Abrahamsson
Shau-Yin Ha
Ólafur G Jónsson
Gertjan JL Kaspers
Minna Koskenvuo
Birgitte Lausen
Barbara De Moerloose
Josefine Palle
et al.
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2018
Cancer-related mRNA expression analysis using a novel flow cytometry-based assay
Barbara Depreter
Jan Philippé
MAGALI MEUL
Barbara Denys
Karl Vandepoele
Barbara De Moerloose
Tim Lammens
A1
Journal Article
in
CYTOMETRY PART B-CLINICAL CYTOMETRY
2018
Compatibility of baclofen, carvedilol, hydrochlorothiazide, mercaptopurine, methadone hydrochloride, oseltamivir phosphate, phenobarbital, propranolol hydrochloride, pyrazinamide, sotalol hydrochloride, spironolactone, Tacrolimus monohydrate, ursodeoxycholic acid, and vancomycin hydrochloride oral suspensions compounded with SyrSpend SF pH4
H Polonini
S L Da Silva
M A F Brandao
Tieneke Bauters
Barbara De Moerloose
A O Ferreira
A2
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICAL COMPOUNDING
2018
Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia. A NOPHO-DBH-AML study
Ninna Bager
Kristian L. Juul-Dam
Julie D. Sandahl
Jonas Abrahamsson
Berna Beverloo
Eveline S. J. M. de Bont
Shau-Yin Ha
Kirsi Jahnukainen
Olafur G. Jonsson
Gertjan L. Kaspers
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2018
Differences in infection prophylaxis measures between paediatric acute myeloid leukaemia study groups within the international Berlin-Frankfurt-Munster (I-BFM) study group
Kim Klein
Henrik Hasle
Jonas Abrahamsson
Barbara De Moerloose
Gertjan J. L. Kaspers
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2018
Exploring the long non-coding RNA landscape in juvenile myelomonocytic leukemia
Mattias Hofmans
Tim Lammens
S Bresolin
H Cavé
C Flotho
H Hasle
Hetty Helsmoortel
M Van den Heuvel-Eibrink
C Niemeyer
J Stary
et al.
C3
Conference
2018
Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia
Elena J. Orlando
Xia Han
Catherine Tribouley
Patricia A. Wood
Rebecca J. Leary
Markus Riester
John E. Levine
Muna Qayed
Stephan A. Grupp
Michael Boyer
et al.
A1
Journal Article
in
NATURE MEDICINE
2018
Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients
Diana Hanekamp
Barbara Denys
Gertjan JL Kaspers
Jeroen G te Marvelde
Gerrit Jan Schuurhuis
Valerie De Haas
Barbara De Moerloose
Eveline S de Bont
C Michel Zwaan
Anja de Jong
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2018
Oral microbiota reduce wound healing capacity of epithelial monolayers, irrespective of the presence of 5-fluorouracil
Eline Vanlancker
Barbara Vanhoecke
Tom Sieprath
Janie Bourgeois
Annelore Beterams
Barbara De Moerloose
Winnok De Vos
Tom Van de Wiele
A1
Journal Article
in
EXPERIMENTAL BIOLOGY AND MEDICINE
2018
Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma
Renate De Smedt
Sofie Peirs
Julie Morscio
Filip Matthijssens
Juliette Roels
Lindy Reunes
Béatrice Lintermans
Steven Goossens
Tim Lammens
Nadine Van Roy
et al.
A1
Journal Article
in
HAEMATOLOGICA
2018
Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML : a retrospective study by the I-BFM Study Group
Sanne Noort
Martin Zimmermann
Dirk Reinhardt
Wendy Cuccuini
Martina Pigazzi
Jenny Smith
Rhonda E. Ries
Todd A. Alonzo
Betsy Hirsch
Daisuke Tomizawa
et al.
A1
Journal Article
in
BLOOD
2018
Recurrently affected genes in juvenile myelomonocytic leukaemia
Julia C Obenauer
Francois G Kavelaars
Mathijs A Sanders
Andrica CH de Vries
Valerie de Haas
H Berna Beverloo
Barbara De Moerloose
Tim Lammens
Michael Dworzak
Remco M Hoogenboezem
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2018
Retrospective study of infant leukaemia in the University Hospitals of Leuven and Ghent
Barbara De Moerloose
E Nauwynck
K Arts
Leen Willems
V Labarque
Tim Lammens
A Uyttebroeck
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2018
RNA-based FLT3-ITD allelic ratio is associated with outcome and ex vivo response to FLT3 inhibitors in pediatric AML
David G. J. Cucchi
Barbara Denys
Gertjan J. L. Kaspers
Jeroen J. W. M. Janssen
Gert J. Ossenkoppele
Valerie de Haas
C. Michel Zwaan
Marry M. van den Heuvel-Eibrink
Jan Philippé
Tamas Csikos
et al.
A1
Journal Article
in
BLOOD
2018
The genetic basis and cell of origin of mixed phenotype acute leukaemia
Thomas B. Alexander
Zhaohui Gu
Ilaria Iacobucci
Kirsten Dickerson
John K. Choi
Beisi Xu
Debbie Payne-Turner
Hiroki Yoshihara
Mignon L. Loh
John Horan
et al.
A1
Journal Article
in
NATURE
2018
The impact of chemotherapy on the host microbiota in the context of oral and gastrointestinal mucositis
Eline Vanlancker
Barbara Vanhoecke
Barbara De Moerloose
Tom Van de Wiele
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2018
The long non-coding RNA landscape in juvenile myelomonocytic leukemia
Mattias Hofmans
Tim Lammens
Hetty Helsmoortel
Silvia Bresolin
Hélène Cavé
Christian Flotho
Henrik Hasle
Marry M van den Heuvel-Eibrink
Charlotte Niemeyer
Jan Stary
et al.
A1
Journal Article
in
HAEMATOLOGICA
2018
Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia
SL Maude
TW Laetsch
J Buechner
S Rives
M Boyer
H Bittencourt
P Bader
MR Verneris
HE Stefanski
GD Myers
et al.
A1
Journal Article
in
NEW ENGLAND JOURNAL OF MEDICINE
2018
2017
Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia : the experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents
Frédéric Millot
Christelle Dupraz
Joelle Guilhot
Meinolf Suttorp
Françoise Brizard
Thierry Leblanc
Adalet Meral Günes
Petr Sedlacek
Evelyne De Bont
Chi Kong Li
et al.
A1
Journal Article
in
CANCER
2017
Bijwerkingen van 'immune checkpoint' inhibitoren : waar dient een huisarts alert op te zijn?
S De Keukeleire
Tessa Kerre
Piet Ost
Barbara De Moerloose
Karim Vermaelen
Lieve Brochez
Vibeke Kruse
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2017
Characteristics and outcome in patients with central nervous system involvement treated in European pediatric acute myeloid leukemia study groups
Ursula Creutzig
Michael N Dworzak
Martin Zimmermann
Dirk Reinhardt
Lucie Sramkova
Jan Pierre Bourquin
Henrik Hasle
Jonas Abrahamsson
Gertjan Kaspers
Mary M van den Heuvel
et al.
A1
Journal Article
in
PEDIATRIC BLOOD & CANCER
2017
Digital multiplex ligation-dependent probe amplification for detection of key copy number alterations in T- and B-cell lymphoblastic leukemia
Anne Benard-Slagter
Ilse Zondervan
Karel de Groot
Farzaneh Ghazavi
Virinder Sarhadi
Pieter Van Vlierberghe
Barbara De Moerloose
Claire Schwab
Kim Vettenranta
Christine J Harrison
et al.
A1
Journal Article
in
JOURNAL OF MOLECULAR DIAGNOSTICS
2017
Genetic insights in ETV6/RUNX1-positive B-cell precursor acute lymphoblastic leukaemia
Farzaneh Ghazavi
Tim Lammens
Pieter Van Vlierberghe
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2017
Novel molecular genetic insights in paediatric B-cell precursor acute lymphoblastic leukaemia
Farzaneh Ghazavi
Tim Lammens
Pieter Van Vlierberghe
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2017
Prognostic discrimination based on the EUTOS long-term survival score within the International Registry for Chronic Myeloid Leukemia in children and adolescents
Frédéric Millot
Joëlle Guilhot
Meinolf Suttorp
Adalet Meral Günes
Petr Sedlacek
Eveline De Bont
Chi Kong Li
Krzysztof Kalwak
Birgitte Lausen
Srdjana Culic
et al.
A1
Journal Article
in
HAEMATOLOGICA
2017
Prolonged versus standard native E-coli asparaginase therapy in childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma : final results of the EORTC-CLG randomized phase III trial 58951
Veerle Mondelaers
Stefan Suciu
Barbara De Moerloose
Alina Ferster
Francoise Mazingue
Geneviève Plat
Karima Yakouben
Anne Uyttebroeck
Patrick Lutz
Vitor Costa
et al.
A1
Journal Article
in
HAEMATOLOGICA
2017
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia
Daniel B Lipka
Tania Witte
Reka Toth
Jing Yang
Manuel Wiesenfarth
Peter Noellke
Alexandra Fischer
David Brocks
Zuguang Gu
Jeongbin Park
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2017
The ION-Ghent guidelines for the management of immune related adverse events (irAE's)
Vibeke Kruse
Max Schreuer
Karim Vermaelen
Piet Ost
Tessa Kerre
Barbara De Moerloose
Lieve Brochez
A2
Journal Article
in
BELGIAN JOURNAL OF MEDICAL ONCOLOGY
2017
Unravelling the biology of juvenile myelomonocytic leukaemia using transcriptomics
Hetty Helsmoortel
Tim Lammens
Pieter Van Vlierberghe
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2017
2016
A novel multiplex NGS-based digital MLPA assay for copy number detection of 700 target sequences in childhood acute lymphoblastic leukemia
Anne Benard
Ilse Zondervan
Jan Schouten
Karel de Groot
Farzaneh Ghazavi
Virinder Sarhadi
Pieter Van Vlierberghe
Barbara De Moerloose
Christine Harrison
Claire Schwab
et al.
C3
Conference
2016
Analysis of a global registration trial of the efficacy and safety of CTL019 in pediatric and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL)
Stephan A Grupp
Theodore Laetsch
Jochen Buechner
Henrique Bittencourt
Shannon L Maude
Michael R Verneris
Gary D Myers
Michael Boyer
Susana Rives
Barbara De Moerloose
et al.
C3
Conference
2016
Comparison between FLT3-ITD measurements based on RNA and DNA of childhood myeloid leukemia samples
Edwin Sonneveld
Valerie de Haas
Michel Zwaan
Marry van den Heuvel-Eibrink
Jan Philippé
Barbara Denys
Barbara De Moerloose
Eveline de Bont
Gert Jan Kaspers
Jacqueline Cloos
C3
Conference
2016
Digital MLPA(TM) for copy number detection in childhood acute lymphoblasic leukemia : a novel multiplex NGS-based assay
A Benard
Barbara De Moerloose
I Zondervan
Farzaneh Ghazavi
V Sarhadi
Pieter Van Vlierberghe
Tim Lammens
S Knuutila
S Savola
C3
Conference
2016
Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia
Gloria Milani
Kaat Durinck
Filip Matthijssens
Sofie Peirs
Tim Pieters
Lindy Reunes
Béatrice Lintermans
Niels Vandamme
Tim Lammens
Yunlei Li
et al.
C3
Conference
2016
Genomic landscape of pediatric mixed phenotype acute leukemia
Thomas B Alexander
Zhaohui Gu
John K Choi
Mignon Loh
John Horan
Barbara Buldini
Giuseppe Basso
Sarah Elitzur
Valerie de Haas
C Michel Zwaan
et al.
C3
Conference
2016
Identification of candidate oncogenes and chromosomal breakpoint sequencing by targeted locus amplification in T-cell acute lymphoblastic leukemia
Eric Vroegindeweij
Tim Lammens
Kirsten Cante-Barrett
Erik Splinter
A Uyttebroeck
Jessica GC Buijs-Gladdines
Wilco Smits
Peter Vandenberghe
Renate De Smedt
Barbara De Moerloose
et al.
C3
Conference
2016
Impact of age and treatment group in childhood high hyperdiploid low risk B-cell acute lymphoblastic leukemia (ALL) : results of the CLG-EORTC 58951 study
Laura Clement
Stefan Suciu
Isabelle Luquet
Alina Ferster
Karima Yakouben
Anne Uytterbroeck
Catherine Paillard
Nicolas Sirvent
Vitor Costa
Barbara De Moerloose
et al.
C3
Conference
2016
Impact of somatic mutations on the outcome of children and adolescents with therapy-related myelodysplastic syndrome
Brigitte Strahm
Marcin W Wlodarski
Victor B Pastor
Bart Przychodzien
Albert Catala
Michael Dworzak
Oksana Fabri
Henrik Hasle
Kristian Kallay
Riccardo Masetti
et al.
C3
Conference
2016
Leukemia in infants : a retrospective study (1992-2014) in the Ghent University Hospital
Elise Nauwynck
Tim Lammens
Vincent Vakaet
N Van Damme
Yves Benoit
Veerle Mondelaers
Els Vandecruys
Genevieve Laureys
L Vakaet
Barbara De Moerloose
C3
Conference
2016
LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19
Hetty Helsmoortel
Barbara De Moerloose
Tim Pieters
Farzaneh Ghazavi
Silvia Bresolin
Helene Cave
Andrica de Vries
Valerie de Haas
Christian Flotho
Veerle Labarque
et al.
A1
Journal Article
in
HAEMATOLOGICA
2016
LIN28B is overexpressed in pediatric leukemia and regulates LNCRNA H19
Hetty Helsmoortel
Barbara De Moerloose
Silvia Bresolin
Hélèe Cavé
Christian Flotho
Charlotte Niemeyer
Jan Stary
Marry van den Heuvel-Eibrink
Pieter Van Vlierberghe
Tim Lammens
C3
Conference
2016
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia
Hetty Helsmoortel
Silvia Bresolin
Tim Lammens
Hélène Cavé
Peter Noellke
Aurélie Caye
Farzaneh Ghazavi
Andrica de Vries
Henrik Hasle
Veerle Labarque
et al.
A1
Journal Article
in
BLOOD
2016
Mutation landscape in childhood myelodysplastic syndromes : results from EWOG-MDS
Marcin Wlodarski
Victor Pastor
Jan Starý
Riccardo Masetti
Henrik Hasle
Michael Dworzak
Markus Schmugge
Barbara De Moerloose
Marek Ussowicz
Marry van den Heuvel-Eibrink
et al.
C3
Conference
2016
Novel molecular genetic insights in pediatric B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi
Barbara De Moerloose
Pieter Van Vlierberghe
Tim Lammens
Dissertation
2016
Phase I study to evaluate dose, safety and tolerability of the polo-like kinase inhibitor Volasertib in paediatric patients with acute leukaemia and advanced solid tumours
F Doz
F Locatelli
A Baruchel
N Blin
Barbara De Moerloose
D Frappaz
M Dworzak
M Fischer
J Starý
K Riemann
et al.
C3
Conference
2016
Prevalence, clinical characteristics and prognosis of GATA2-related myelodysplastic syndromes (MDS) in children and adolescents
Marcin W Wlodarski
Shinsuke Hirabayashi
Victor Pastor
Jan Starý
Henrik Hasle
Riccardo Masetti
Michael Dworzak
Markus Schmugge
Marry van den Heuvel-Eibrink
Marek Ussowicz
et al.
A1
Journal Article
in
BLOOD
2016
Prognostic discrimination of children and adolescents with chronic myeloid leukemia based on the EUTOS Long Term Survival (ELTS) score
Frédéric Millot
Joelle Guilhot
Meinolf Suttorp
Adalet Meral Günes
Petr Sedlacek
Eveline de Bont
Chi Kong Li
Krzysztof Kalwak
Birgitte Lausen
Srdjana Culic
et al.
C3
Conference
2016
RPPA-Based protein profiling reveals enhanced PI3K/AKT/mTOR signaling in ETV6/RUNX1-positive acute lymphoblastic leukemia patients with low CD200 expression
Farzaneh Ghazavi
Valentina Serafin
Pieter Rondou
Tim Lammens
Franki Speleman
Benedetta Accordi
Barbara De Moerloose
Pieter Van Vlierberghe
C3
Conference
2016
The integrated immunological signature of Refractory Cytopenia of Childhood (RCC)
D de Winter
AW Langerak
JJM van Dongen
M Dworzak
Barbara De Moerloose
J Starý
CM Niemeyer
F Locatelli
H Hasle
M Schmugge
et al.
C3
Conference
2016
Therapy with low-dose azacitidine for MDS in children and young adults: a retrospective analysis of the EWOG-MDS study group
Annamaria M Cseh
Charlotte M Niemeyer
Ayami Yoshimi
Albert Catala
Michael C Frühwald
Henrik Hasle
Mary M van den Heuvel-Eibrink
Melchior Lauten
Barbara De Moerloose
Owen P Smith
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2016
Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi
Barbara De Moerloose
Wouter Van Loocke
Annelynn Wallaert
Alina Ferster
Marleen Bakkus
Geneviève Plat
Eric Delabesse
Anne Uyttebroeck
Filip Van Nieuwerburgh
et al.
C3
Conference
2016
Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi
Barbara De Moerloose
Wouter Van Loocke
Annelynn Wallaert
Hetty Helsmoortel
Alina Ferster
Marleen Bakkus
Geneviève Plat
Eric Delabesse
Anne Uyttebroeck
et al.
A1
Journal Article
in
ONCOTARGET
2016
Unraveling the biology of juvenile myelomonocytic leukemia using transcriptomics
Hetty Helsmoortel
Barbara De Moerloose
Tim Lammens
Pieter Van Vlierberghe
Dissertation
2016
2015
Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood
Anna M Aalbers
Marry M van den Heuvel-Eibrink
Irith Baumann
Michael Dworzak
Henrik Hasle
Franco Locatelli
Barbara De Moerloose
Markus Schmugge
Ester Mejstrikova
Michaela Nováková
et al.
A1
Journal Article
in
HAEMATOLOGICA
2015
CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol
Farzaneh Ghazavi
Emmanuelle Clappier
Tim Lammens
Stefan Suciu
Aurélie Caye
Samira Zegrari
Marleen Bakkus
Nathalie Grardel
Yves Benoit
Odile Minckes
et al.
A1
Journal Article
in
HAEMATOLOGICA
2015
Clinical impact of additional cytogenetic aberrations, cKIT and RAS mutations, and treatment elements in pediatric t(8;21)-AML : results from an international retrospective study by the International Berlin-Frankfurt-Münster study group
Kim Klein
Gertjan Kaspers
Christine J Harrison
H Berna Beverloo
Ardine Reedijk
Mathilda Bongers
Jacqueline Cloos
Andrea Pession
Dirk Reinhardt
Martin Zimmerman
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2015
Clonal mutational landscape of childhood myelodysplastic syndromes
Emilia J Kozyra
Shinsuke Hirabayashi
Victor Bengt Pastor Loyola
Bartlomiej Przychodzen
Axel Karow
Albert Catala
Barbara De Moerloose
Michael Dworzak
Henrik Hasle
Riccardo Masetti
et al.
C3
Conference
2015
Collaborative efforts driving progress in pediatric acute myeloid leukemia
C Michel Zwaan
Edward A Kolb
Dirk Reinhardt
Jonas Abrahamsson
Souichi Adachi
Richard Aplenc
Eveline SJM De Bont
Barbara De Moerloose
Michael Dworzak
Brenda ES Gibson
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2015
Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia
Charlotte M Niemeyer
Mignon L Loh
Annamaria Cseh
Todd Cooper
Christopher C Dvorak
Rebecca Chan
Blanca Xicoy
Ulrich Germing
Seiji Kojima
Atsushi Manabe
et al.
A1
Journal Article
in
HAEMATOLOGICA
2015
Excellent outcome in pediatric AML with response guided chemotherapy without allogeneic HSCT in first complete remission results from prococol DB-AML01
Eveline de Bont
Ardine Reedijk
Tim Lammens
Valerie de Haas
Barbara Denys
Laurence Dedeken
Marry van den Heuvel
Maroeska te Loo
Anne Uyttebroeck
An Vandamme
et al.
C3
Conference
2015
Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study
Hiroto Inaba
Yinmei Zhou
Ousama Abla
Souichi Adachi
Anne Auvrignon
H Berna Beverloo
Eveline de Bont
Tai-Tsung Chang
Ursula Creutzig
Michael Dworzak
et al.
A1
Journal Article
in
BLOOD
2015
IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Chrildren's Leukemia Group study 58951
E Clappier
N Grardel
M Bakkus
J Rapion
Barbara De Moerloose
P Kastner
A Caye
J Vivent
V Costa
A Ferster
et al.
A1
Journal Article
in
LEUKEMIA
2015
Long-term results of the 'Prospective study of the diagnosis and treatment of myelodysplastic syndromes in childhood (EWOG-MDS98)'
A Strauss
A Yoshimi
I Baumann
M Ussowicz
Barbara De Moerloose
B Schlegelberger
M Dworzak
M Schmugge
M Zecca
A Fischer
et al.
C3
Conference
2015
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Michael Boice
Pieter Mestdagh
Inge Van de Walle
Tim Lammens
Steven Goossens
Barbara De Moerloose
Yves Benoit
et al.
A1
Journal Article
in
LEUKEMIA
2015
Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi
Tim Lammens
Nadine Van Roy
Bruce Poppe
Franki Speleman
Yves Benoit
Pieter Van Vlierberghe
Barbara De Moerloose
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY
2015
Mutational spectrum of juvenile myelomonocytic leukemia
J Obenauer
F Kavelaars
ACH de Vries
M Sanders
V de Haas
Barbara De Moerloose
Tim Lammens
M Dworzak
C Niemeyer
P Valk
et al.
C3
Conference
2015
Novel biological insights in T-cell acute lymphoblastic leukemia
Kaat Durinck
Steven Goossens
Sofie Peirs
Annelynn Wallaert
Wouter Van Loocke
Filip Matthijssens
Tim Pieters
Gloria Milani
Tim Lammens
Pieter Rondou
et al.
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY
2015
Phase II study on bortezomib (BTZ) in multiple relapsed or refractory pediatric acute lymphoblastic leukemia (rALL) : high response rate with a modestly intensive regimen including BTZ, not related to pharmacokinetics
Gertjan JL Kaspers
Denise Niewerth
Bram Wilhelm
Satianand Ramnarain
Hans Berkhof
Valerie de Haas
Ron AA Mathôt
Andishe Attarbaschi
Andre Baruchel
Eveline S de Bont
et al.
C3
Conference
2015
Somatic genetic and epigenetic architecture of myelodysplastic syndromes arising from GATA2 deficiency
Victor Bengt Pastor Loyola
Shinsuke Hirabayashi
Sandra Pohl
Emilia J Kozyra
Albert Catala
Barbara De Moerloose
Marek Dworzak
Henrik Hasle
Riccardo Masetti
Markus Schmugge
et al.
C3
Conference
2015
Switch to subsequent line of treatment in children and adolescents with chronic myeloid leukemia (CML) treated with imatinib : experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents (I-CML-Ped study)
Frédéric Millot
Joelle Guilhot
Meinolf Suttorp
Anne Sophie Meunier
Gunes Adalet Meral
Per Sedlacek
Eveline de Bont
Chi Kong Li
Krzysztof Kalwak
Brigitte Lausen
et al.
C3
Conference
2015
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Joni Van der Meulen
Viraj Sanghvi
Konstantinos Mavrakis
Kaat Durinck
Fang Fang
Filip Matthijssens
Pieter Rondou
Monica Rosen
Tim Pieters
Peter Vandenberghe
et al.
A1
Journal Article
in
BLOOD
2015
The integrated immunological signature of refractory cytopenia of childhood (RCC)
Demi de Winter
Marry M van den Heuvel-Eibrink
Vincent HJ van der Velden
Anton W Langerak
Jacques JM van Dongen
Michael Dworzak
Barbara De Moerloose
Jan Starý
Charlotte M Niemeyer
Franco Locatelli
et al.
C3
Conference
2015
The long non-coding RNA H19 is regulated by LIN28B
Hetty Helsmoortel
Barbara De Moerloose
Tim Pieters
Farzaneh Ghazavi
S Bresolin
H Cavé
A Caye
ACH de Vries
C Flotho
V Labarque
et al.
C3
Conference
2015
The relevance of stem cell load at diagnosis for the development of relapse in pediatric acute myeloid leukemia
Dirkje W Hanekamp
Barbara Denys
Gerjan JL Schuurhuis
Jeroen G te Marvelde
Valerie de Haas
Barbara De Moerloose
Eveline S de Bont
Anja de Jong
Jan Philippé
Jacqueline Cloos
et al.
C3
Conference
2015
2014
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in early immature T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Steven Goossens
Kirsten Canté-Barrett
Tim Lammens
Barbara De Moerloose
Yves Benoit
Jean Soulier
Bruce Poppe
Tom Taghon
et al.
C3
Conference
2014
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Steven Goossens
Inge Van de Walle
Katia Ruggero
Charles E de Bock
Sandrine Degryse
Kirsten Canté-Barrett
Delphine Briot
Emmanuelle Clappier
et al.
A1
Journal Article
in
BLOOD
2014
ABT-199 mediated inhibition of BCL2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Sofie Peirs
Filip Matthijssens
Steven Goossens
Charles De Bock
Kirsten Canté-Barrett
Tim Lammens
Inge Van de Walle
Barbara De Moerloose
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2014
Anthracycline type during induction associated with outcome in pediatric t(8;21) and inv(16) AML
Henrik Hasle
Jonas Abrahamsson
Evelina S De Bont
Valerie de Haas
Barbara De Moerloose
Erik Forestier
Shau Yin Ha
Jesper Heldrup
Kirsi Jahnukainen
Olafur G Jonsson
et al.
C3
Conference
2014
Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood
Anna Aalbers
Marry Van Den Heuvel-Eibrink
Irith Baumann
Michael Dworzak
Henrik Hasle
Franco Locatelli
Barbara De Moerloose
Markus Schmugge
Ester Mejstrikova
Michaela Novakova
et al.
C3
Conference
2014
Clinical impact of additional cytogenetic aberrations, cKIT- and RAS mutations and other factors in pediatric t(8;21)-AML
Kim Klein
Gertjan Kaspers
Christine J Harrison
Berna Beverloo
Ardine Reedijk
Mathilda Bongers
Jacqueline Cloos
Andrea Pession
Dirk Reinhardt
Martin Zimmermann
et al.
C3
Conference
2014
Comparison of horse and rabbit antithymocyte globulin in immunosuppressive therapy for refractory cytopenia of childhood
Ayami Yoshimi
Marry M van den Heuvel-Eibrink
Irith Baumann
Stephan Schwarz
Ingrid Simonitsch-Klupp
Pascale De Paepe
Vit Campr
Gitte Birk Kerndrup
Maureen O'Sullivan
Rita Devito
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
Dexamethasone (6 mg/m²/day) and prednisolone (60 mg/m²/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial
Carine Domenech
Stefan Suciu
Barbara De Moerloose
Françoise Mazingue
Geneviève Plat
Alina Ferster
Anne Uyttebroeck
Nicolas Sirvent
Patrick Lutz
Karima Yakouben
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
Fatal Myceliophthora thermophila infection in a boy with acute myeloid leukaemia and cord blood stem cell transplantation
A Piette
Barbara De Moerloose
Petra Schelstraete
Maria Bordon Cueto De Braem
Thierry De Baere
Geert Claeys
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2014
Impact of minimal residual disease monitoring on therapy in Belgian childhood acute lymphoblastic leukaemia
J Van der Straeten
Barbara De Moerloose
MF Dresse
S Dupont
A Ferster
P Philippet
A Uyttebroeck
J van der Werff ten Bosch
C Demanet
Yves Benoit
et al.
C3
Conference
2014
Juvenile myelomonocytic leukaemia: the quest for more specific therapies
Hetty Helsmoortel
Tim Lammens
Nadine Van Roy
Jan Philippé
Pascale De Paepe
Yves Benoit
Franki Speleman
Pieter Van Vlierberghe
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2014
Juvenile myelomonocytic leukemia : five genes, how many subtypes?
Charlotte M Niemeyer
Brigitte Strahm
Michael Dworzak
Barbara De Moerloose
Henrik Hasle
Jan Stary
Markus Schmugge
Marek Ussowics
Marry Van Den Heuvel-Eibrink
Marco Zecca
et al.
C3
Conference
2014
LIN28B defines an aggressive subtype of juvenile myelomonocytic leukemia
Hetty Helsmoortel
Tim Lammens
Farzaneh Ghazavi
Aurelie Caye
Hélène Cavé
Christian Flotho
Charlotte Niemeyer
Jan Stary
Silvia Bresolin
Riccardo Masetti
et al.
C3
Conference
2014
MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia
Evelien Mets
Gert Van Peer
Joni Van der Meulen
Michael Boice
Tom Taghon
Steven Goossens
Pieter Mestdagh
Yves Benoit
Barbara De Moerloose
Nadine Van Roy
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
Mind the gap : translation of genetic research into clinical care in the context of RUNX1-associated leukaemia predisposition
Tim Ripperger
Alina Ferster
Tim Lammens
Barbara De Moerloose
Laurence Rozen
Nadira Azzi
Charlotte M Niemeyer
Brigitte Schlegelberger
Doris Steinemann
C3
Conference
2014
Minimal residual disease quantification by PCR in childhood acute lymphoblastic leukaemia
J Van der Straeten
Barbara De Moerloose
MF Dresse
S Dupont
A Ferster
P Philippet
A Uyttebroeck
J van der Werff ten Bosch
C Demanet
Yves Benoit
et al.
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2014
Pediatric acute megakaryoblastic leukemia without Down syndrome: a retrospective study by the international Berlin-Frankfurt-Munster study group (I-BFMSG)
Hiroto Inaba
Yinmei Zhou
Oussama Abla
Souichi Adachi
Anne Auvrignon
Berna Beverloo
Eveline De Bont
Tai-Tsung Chang
Ursula Creutzig
Nicole Dastugue
et al.
C3
Conference
2014
Prognostic relevance of BTLA/CD200 deletion in pediatric pre-B cell acute lymphoblastic leukemia
Farzaneh Ghazavi
Tim Lammens
Stefan Suciu
Marleen Bakkus
Hélène Cavé
Franki Speleman
Yves Benoit
Barbara De Moerloose
Pieter Van Vlierberghe
C3
Conference
2014
Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol
Farzaneh Ghazavi
Tim Lammens
Emmanuelle Clappier
Stefan Suciu
Aurélie Caye
Samira Zegrari
Marleen Bakkus
Nathalie Grardel
Yves Benoit
Yves Bertrand
et al.
C3
Conference
2014
RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia
Anna R Poetsch
Daniel B Lipka
Tania Witte
Rainer Claus
Peter Nöllke
Manuela Zucknick
Christiane Olk-Batz
Silvia Fluhr
Michael Dworzak
Barbara De Moerloose
et al.
A1
Journal Article
in
EPIGENETICS
2014
Reduced intensity conditioning for children with refractory cytopenia of childhood : results of the EWOG-MDS study SCT RX RIC 06
Brigitte Strahm
Peter Bader
Albert Catala
Michael Dworzak
Marry Vandenheuvel
Barbara De Moerloose
Markus Schmugge
Owen Smith
Petr Sedlacek
Franco Locatelli
et al.
C3
Conference
2014
Results of a feasibility and phase II study on bortezomib (BTZ) in pediatric multiply relapsed of refractory acute lymphoblastic leukemia: complete hematological responses with a modestly intensive regimen including BTZ
Gertjan Kaspers
Denise Niewerth
Satianand Ramnarain
Andishe Attarbaschi
André Baruchel
Evelina S De Bont
Franca Fagioli
Barbara De Moerloose
Karsten Nysom
Giuseppe Palumbo
et al.
C3
Conference
2014
T-cell receptor Vβ skewing frequently occurs in refractory cytopenia of childhood and is associated with an expansion of effector cytotoxic T cells: a prospective study by EWOG-MDS
AM Aalbers
MM van den Heuvel-Eibrink
I Baumann
HB Beverloo
GJ Driessen
M Dworzak
A Fischer
G Göhring
H Hasle
F Locatelli
et al.
A1
Journal Article
in
BLOOD CANCER JOURNAL
2014
The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS
AM Aalbers
VHJ van der Velden
A Yoshimi
A Fischer
P Noellke
CM Zwaan
I Baumann
HB Beverloo
M Dworzak
H Hasle
et al.
A1
Journal Article
in
LEUKEMIA
2014
The prognostic value of leukemic stem cells in pediatric AML
Bram De Caluwé
Rolf Wouters
Valerie De Haas
Jeroen G te Marvelde
Barbara De Moerloose
Eveline S de Bont
Barbara Denys
Anja De Jong
G Kaspers
Jan Philippé
et al.
C3
Conference
2014
Use of rasburicase in prevention and treatment of tumor lysis syndrome in children
Tieneke Bauters
Veerle Mondelaers
Yves Benoit
J Vandenbroucke
Barbara De Moerloose
C3
Conference
2014
2013
Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood
AM Aalbers
MM van den Heuvel-Eibrink
V de Haas
JG te Marvelde
AX de Jong
M van der Burg
M Dworzak
H Hasle
F Locatelli
Barbara De Moerloose
et al.
A1
Journal Article
in
LEUKEMIA
2013
Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood
AM Aalbers
MM Van den Heuvel-Eibrink
V De Haas
JG Te Marvelde
AX De Jong
M van der Burg
M Dworzak
H Hasle
F Locatelli
Barbara De Moerloose
et al.
C3
Conference
2013
Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood
A Aalbers
M Van Den Heuvel-Eibrink
V Haas
J te Marvelde
A de Jong
M van der Burg
M Dworzak
H Hasle
F Locatelli
Barbara De Moerloose
et al.
C3
Conference
2013
Congenital neutropenia
Barbara De Moerloose
A2
Journal Article
in
TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE
2013
Cost-minimisation of PEG-L-asparaginase versus native L-asparaginase for the treatment of children with acute lymphoblastic leukemia in Belgium
Tieneke Bauters
Veerle Mondelaers
Barbara De Moerloose
Hugo Robays
Yves Benoit
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2013
Delayed elemination of methotrexate by cola beverages in a pediatric acute lymphoblastic leukemia population
Tieneke Bauters
Tim Lammens
Pauline Belin
Yves Benoit
Hugo Robays
Barbara De Moerloose
A1
Journal Article
in
LEUKEMIA & LYMPHOMA
2013
Highly elevated liver enzymes related to the use of gabapentin in a child treated for high-risk neuroblastoma
Tieneke Bauters
Barbara De Moerloose
Hugo Robays
Yves Benoit
Genevieve Laureys
C3
Conference
2013
Impact of MRD status prior to HSCT in pediatric AML
M Hansen
C Nyvold
L Ebbesen
D Reinhardt
G Kaspers
J Stary
Barbara De Moerloose
M Dworzak
C Zwaan
H Hasle
C3
Conference
2013
Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia
Tieneke Bauters
Veerle Mondelaers
Hugo Robays
Hans De Wilde
Yves Benoit
Barbara De Moerloose
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
2013
MiR-128 is a novel PHF6 targeting regulatory non-coding RNA acting as a T-ALL oncogene
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Michael Boice
Pieter Mestdagh
Tom Taghon
David Avran
Barbara De Moerloose
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2013
miRNAs distinguish children with myelodysplastic syndrome from healthy donors
Hetty Helsmoortel
Tim Lammens
Pieter Mestdagh
Nadine Van Roy
Anne Uyttebroeck
Alina Ferster
Yves Benoit
Jo Vandesompele
Franki Speleman
Pieter Van Vlierberghe
et al.
C3
Conference
2013
miRNAs distinguish children with myelodysplastic syndrome from healthy donors
Hetty Helsmoortel
Tim Lammens
Pieter Mestdagh
Nadine Van Roy
Anne Uyttebroeck
Alina Ferster
Yves Benoit
Jo Vandesompele
Franki Speleman
Pieter Van Vlierberghe
et al.
C3
Conference
2013
Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International Berlin-Frankfurt-Munster AML-study group
Eva A Coenen
C Michel Zwaan
Dirk Reinhardt
Christine J Harrison
Oskar A Haas
Valerie de Haas
Vladimir Mihál
Barbara De Moerloose
Marta Jeison
Jeffrey E Rubnitz
et al.
A1
Journal Article
in
BLOOD
2013
Pediatric acute myeloid leukemia with t(8;16)(p11;p13): a distinct clinical and biological entity: results of a collaborative study by the international Berlin-Frankfurt-Münster AML Study Group
E Coenen
CM Zwaan
D Reinhardt
C Harrison
O Haas
V De Haas
V Mihal
Barbara De Moerloose
M Jeison
J Rubnitz
et al.
C3
Conference
2013
PEG-asparaginase in treatment of childhood acute lymphoblastic leukemia
Veerle Mondelaers
Tieneke Bauters
Barbara De Moerloose
Yves Benoit
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2013
SNX10 mutations define a subgroup of human Autosomal Recessive Osteopetrosis with variable clinical severity
Alessandra Pangrazio
Anders Fasth
Andrea Sbardellati
Paul J Orchard
Kimberly A Kasow
Jamal Raza
Canan Albayrak
Davut Albayrak
Olivier Vanakker
Barbara De Moerloose
et al.
A1
Journal Article
in
JOURNAL OF BONE AND MINERAL RESEARCH
2013
The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood : a prospective study by EWOG-MDS
A Aalbers
V Van Der Velden
A Yoshimi
A Fischer
P Noellke
C Zwaan
I Baumann
H Beverloo
M Dworzak
H Hasle
et al.
C3
Conference
2013
The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS
AM Aalbers
VHJ Van der Velden
A Yoshimi
A Fischer
P Noellke
CM Zwaan
I Baumann
HB Beverloo
M Dworzak
H Hasle
et al.
C3
Conference
2013
2012
Improved risk stratification and outcome prediction in children with average risk 1 precursor-B acute lymphoblastic leukemia using a 19-microRNA signature
Farzaneh Ghazavi
Tim Lammens
Stefan Suciu
Genevieve Laureys
Marleen Bakkus
Alina Ferster
Anne Uyttebroeck
Patrick Lutz
Hélène Cavé
Geneviève Plat
et al.
C3
Conference
2012
Improved risk-stratification and outcome prediction in children with average risk precursor-B acute lymphoblastic leukemia using a 19-microRNA signature
Farzaneh Ghazavi
Tim Lammens
Stefan Suciu
Genevieve Laureys
Marleen Bakkus
Alina Ferster
Anne Uyttebroeck
Patrick Lutz
Hélène Cavé
Geneviève Plat
et al.
C3
Conference
2012
Methotrexate in children with acute lymphoblastic leukaemia : impact of pharmacogenetic polymorphisms on plasma concentration, toxicity and outcome
Lien Cattoir
Liesbeth Huys
Paul Coucke
Yves Benoit
Tieneke Bauters
Barbara De Moerloose
C3
Conference
2012
Musculoskeletal manifestations in children with acute lymphoblastic leukaemia
HILDE MULDER
Nele Herregods
Veerle Mondelaers
Yves Benoit
VALERIE MEERSSCHAUT
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2012
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML
Shinsuke Hirabayashi
Christian Flotho
Jessica Moetter
Michael Heuser
Henrik Hasle
Bernd Gruhn
Thomas Klingebiel
Felicitas Thol
Brigitte Schlegelberger
Irith Baumann
et al.
A1
Journal Article
in
BLOOD
2012
Study of the miRNome of childhood myelodysplastic syndrome
Hetty Helsmoortel
Tim Lammens
Nadine Van Roy
Anne Uyttebroeck
Alina Ferster
Yves Benoit
Franki Speleman
Barbara De Moerloose
C3
Conference
2012
2011
Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome
Christiane Olk-Batz
Anna R Poetsch
Peter Nöllke
Rainer Claus
Manuela Zucknick
Inga Sandrock
Tania Witte
Brigitte Strahm
Henrik Hasle
Marco Zecca
et al.
A1
Journal Article
in
BLOOD
2011
Etoposide in continuous infusion: practical recommendations for pediatric protocols
Tieneke Bauters
Johan Vandenbroucke
Barbara De Moerloose
JOHAN DE PORRE
Yves Benoit
Hugo Robays
A2
Journal Article
in
JOURNAL OF ONCOLOGY PHARMACY PRACTICE
2011
Hematopoietic stem cell transplantation for advanced myelodysplastic syndrome in children: results of the EWOG-MDS 98 study
B Strahm
P Nollke
M Zecca
ET Korthof
M Bierings
I Furlan
P Sedlacek
A Chybicka
M Schmugge
Maria Bordon Cueto De Braem
et al.
A1
Journal Article
in
LEUKEMIA
2011
IER3 expression in childhood myelodysplastic syndrome
Andrica de Vries
Christian M Zwaan
Astric Danen-Van Oorschot
Valerie de Haas
Henrik Hasle
Franco Locatelli
Barbara De Moerloose
Sophia Polychronopoulou
Jan Stary
Markus Schmugge
et al.
C3
Conference
2011
Immunosuppressive therapy with anti-thymocyte globin and cyclosporine A in patients with refractory cytopenia in childhood
A Yoshimi-Nollke
MM van den Heuvel-Eibrink
I Baumann
M Fuhrer
Barbara De Moerloose
M Dworzak
J Stary
M Schmugge
M Zecca
P Nollke
et al.
C3
Conference
2011
Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia
Tieneke Bauters
Veerle Mondelaers
Hugo Robays
Hans De Wilde
Yves Benoit
Barbara De Moerloose
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
2011
MicroRNA-based diagnosis, prognosis and treatment of paediatric acute lymphoblastic leukaemia
Tim Lammens
Farzaneh Ghazavi
Franki Speleman
Yves Benoit
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2011
Mutations of the spliceosome complex genes occur in adult patients but are very rare in children with myeloid neoplasia
Shinsuke Hirabayashi
Jessica Moetter
Kenichi Yoshida
Michael Heuser
Henrik Hasle
Alexandra Fischer
Brigitte Strahm
Brigitte Schlegelberger
Irith Baumann
Felicitas Thol
et al.
C3
Conference
2011
Off-label and unlicensed use in a pediatric hemato-oncology unit
Tieneke Bauters
Barbara De Moerloose
VERONIQUE VAN DE VELDE
Myriam Van Winckel
Hugo Robays
Yves Benoit
JORIS VERLOOY
C3
Conference
2011
Similar efficacy and toxicity profile for Idarubicine and Mitoxantrone in induction and intensification treatment of children with acute myeloid leukemia (AML) or myelodysplasia (MDS): long-term results of the EORTC-CLG randomized phase III trial 58921
Barbara De Moerloose
Stefan Suciu
Martine Munzer
Caroline Piette
Karima Yakouben
Genevieve Margueritte
Patrick Lutz
Anne Uyttebroeck
Pierre Rohrlich
Alina Ferster
et al.
C3
Conference
2011
Stem cell transplantation for therapy-related myelodysplastic syndrome following treatment for childhood acute lymphoblastic leukaemia
B Strahm
R Amann
Barbara De Moerloose
M Dworzak
H Hasle
M Schmugge
J Stary
MM van den Heuvel-Eibrink
M Zecca
F Locatelli
et al.
C3
Conference
2011
The use of propranolol in the treatment of periocular infantile haemangiomas: a review
Ilse Claerhout
MICHIEL BUIJSROGGE
P Delbeke
SOPHIE WALRAEDT
Sophie De Schepper
Barbara De Moerloose
Katya De Groote
CHRISTIAN DECOCK
A1
Journal Article
in
BRITISH JOURNAL OF OPHTHALMOLOGY
2011
Therapy-related myelodysplastic syndrome following treatment for childhood acute lymphoblastic leukemia: outcome of patients registered in the EWOG-MDS 98/06 studies
Brigitte Strahm
Roland Amann
Barbara De Moerloose
Michael Dworzak
Henrik Hasle
Markus Schmugge
Jan Stary
Marry M Van den Heuvel-Eibrik
Marco Zecca
Brigitte Schlegelberger
et al.
C3
Conference
2011
Treatment of refractory T-lymphoblastic leukaemia and lymphoma with nelarabine
Tieneke Bauters
Hugo Robays
Yves Benoit
Barbara De Moerloose
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2011
2010
Asparaginase levels, antibodies and silent inactivation in childhood acute lymphoblastic leukemia
Veerle Mondelaers
M Dewulf
Brigitte Wuyts
Brecht De Cuyper
Yves Benoit
Barbara De Moerloose
C3
Conference
2010
Bresolin_2010_Gene exGene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia
Silvia Bresolin
Marco Zecca
Christian Flotho
Luca Trentin
Andrea Zangrando
Laura Sainati
Jan Stary
Barbara De Moerloose
Henrik Hasle
Charlotte M Niemeyer
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2010
Gastric ulcer in a child treated with deferasirox
Tieneke Bauters
Veerle Mondelaers
Hugo Robays
KATHLEEN HUNNINCK
Barbara De Moerloose
A1
Journal Article
in
PHARMACY WORLD & SCIENCE
2010
Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951
Barbara De Moerloose
Stefan Suciu
Yves Bertrand
Françoise Mazingue
Alain Robert
Anne Uyttebroeck
Karima Yakouben
Alice Ferster
Geneviève Margueritte
Patrick Lutz
et al.
A1
Journal Article
in
BLOOD
2010
Methemoglobinemia and hemolytic anemia caused by Rasburicase administration in a child with acute lymphoblastic leukemia
Tieneke Bauters
Veerle Mondelaers
Hugo Robays
Hans De Wilde
Yves Benoit
Barbara De Moerloose
C3
Conference
2010
Microrna expression in pediatric precursor-B acute lymphoblastic leukemia: biology, classification and prognosis
Tim Lammens
Barbara De Moerloose
Jonas Van Baelen
Joni Van der Meulen
Pieter Mestdagh
Bruno Verhasselt
Jan Philippé
Franki Speleman
Yves Benoit
C3
Conference
2010
PHF6 mutations in T-cell acute lymphoblastic leukemia
Pieter Van Vlierberghe
Teresa Palomero
Hossein Khiabanian
Joni Van der Meulen
Mireia Castillo
Nadine Van Roy
Barbara De Moerloose
Jan Philippé
Sara Gonzalez-Garcia
Maria L Toribio
et al.
A1
Journal Article
in
NATURE GENETICS
2010
Presentation and outcome of children with down syndrome and acute lymphoblastic leukemia in the eortc children's leukemia group protocol 58951
Veerle Mondelaers
Barbara De Moerloose
S Suciu
A Ferster
P Lutz
A Uyttebroeck
D Plantaz
L Norton
N Sirvent
A Robert
et al.
C3
Conference
2010
Refractory Cytopenia in Childhood (RCC) with normal karyotype is unlikely to progress to advanced MDS under a watch and wait strategy
Shinsuke Hirabayashi
Brigitte Strahm
Stephan Schwarz
Marco Zecca
Markus Schmugge
Michael Dworzak
Marry Van Den Heuvel-Eibrink
Henrik Hasle
Barbara De Moerloose
Jan Stary
et al.
C3
Conference
2010
The Dutch-Belgian pediatric acute myeloid leukemia protocol for children with newly diagnosed acute myeloid leukemie (DB AML-01)
Barbara De Moerloose
ESJM de Bont
A2
Journal Article
in
BELGIAN JOURNAL OF HEMATOLOGY
2010
Weblogs of parents with a child treated for cancer: their intentions and experiences
VERONIQUE VAN DE VELDE
Ilse Demares
Patricia De Vos
JOHAN DE PORRE
Barbara De Moerloose
Yves Benoit
Gino Verleye
C3
Conference
2010
2009
A fatal myceliophthora thermophila infection in a child with acute myeloid leukaemia
Anne Piette
Barbara De Moerloose
Veerle Mondelaers
Petra Schelstraete
Thierry De Baere
Gerda Verschraegen
Geert Claeys
C3
Conference
2009
Aberrant DNA Methylation characterizes a subtype of juvenile myelomonocytic leukemia (JMML) with poor outcome
C Batz
I Sandrock
P Nöllke
B Strahm
H Hasle
M Zecca
J Stary
E Bergsträsser
Barbara De Moerloose
M Trebo
et al.
C3
Conference
2009
CLINICAL PHARMACY ACTIVITIES AT A PEDIATRIC HEMATO-ONCOLOGY UNIT
Tieneke Bauters
JORIS VERLOOY
JOHAN DE PORRE
Barbara De Moerloose
Yves Benoit
Hugo Robays
C3
Conference
2009
Clinical pharmacy activities at a Pediatric Hemato-Oncology Unit
Tieneke Bauters
JORIS VERLOOY
JOHAN DE PORRE
Barbara De Moerloose
Yves Benoit
Hugo Robays
C3
Conference
2009
Is the risk of developing AML or MDS increased in X-linked neutropenia
K Beel
M Cotter
J Blatny
C Chatelain
A Uyttebroeck
Barbara De Moerloose
Nadine Van Roy
G. Verhoef
H Demuynck
P Vandenberghe
C3
Conference
2009
MICRORNA SIGNATURES IN GENETIC SUBTYPES OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Joni Van der Meulen
Pieter Van Vlierberghe
Pieter Mestdagh
Jo Vandesompele
Bruce Poppe
Nadine Van Roy
Tom Taghon
Jean Plum
B. Cauwelier
DLD Selleslag
et al.
C3
Conference
2009
Mutational Screening in refractory cytopenia - in search of underlying SDS.
A. Karow
M. Fliegauf
E. Bergsträsser
H. Hasle
M. Van Den Heuvel-Eibrink
F. Locatelli
S. Matthes-Martin
Barbara De Moerloose
J. Stary
D. Wójcik
et al.
C3
Conference
2009
Myelodysplastic syndromes in adolescents: characteristics and clinical outcome
Marco Zecca
Peter Noellke
Eva Bergsträßer
Barbara De Moerloose
Henrik Hasle
Susanne Matthes-Martin
Laura Sainati
Jan Stary
Brigitte Strahm
Marry M. Van Den Heuvel-Eibrink
et al.
C3
Conference
2009
Myelodysplastisch syndroom en juveniele myelomonocytaire leukemie bij kinderen
A de Vries
Barbara De Moerloose
E van Wering
M van den Heuvel-Eibrink
A4
Journal Article
in
NEDERLANDS TIJDSCHRIFT VOOR HEMATOLOGIE
2009
Role of the inhibitory KIR ligand HLA-Bw4 and HLA-C expression levels in the recognition of leukemic cells by Natural Killer cells.
Sonja Verheyden
Soldano Ferrone
Arend Mulder
Frans Claas
Rik Schots
Barbara De Moerloose
Yves Benoit
Christian Demanet
A1
Journal Article
in
CANCER IMMUNOLOGY IMMUNOTHERAPY
2009
2008
Evaluation of nutritional support in children undergoing haematopoietic stem cell transplantation: a single-centre experience
Sophie Van Lancker
Maria Bordon Cueto De Braem
JOHAN DE PORRE
Barbara De Moerloose
Els Vandecruys
JORIS VERLOOY
Genevieve Laureys
Catharina Dhooge
Yves Benoit
C3
Conference
2008
EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22
An De Weer
Franki Speleman
Barbara Cauwelier
Nadine Van Roy
Nurten Yigit
Bruno Verhasselt
Barbara De Moerloose
Yves Benoit
Lucien Noens
Dominik Selleslag
et al.
A1
Journal Article
in
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL
2008
Improved outcome with pulses of Vincristine (VCR) and Steroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and Non Hodgkin Lymphoma (NHL): final report of the EORTC randomized phase III trial 58951
Barbara De Moerloose
S. Suciu
Y. Bertrand
F. Mazingue
A. Robert
A. Uyttebroeck
K. Yacouben
A. Ferster
G. Margueritte
P. Lutz
et al.
C3
Conference
2008
Invasive fungal infection after allogeneic stem cell transplantation in a pediatric population: single center retrospective analysis.
Maria Bordon Cueto De Braem
Veerle Mondelaers
Barbara De Moerloose
Els Vandecruys
JORIS VERLOOY
Yves Benoit
Genevieve Laureys
Catharina Dhooge
C3
Conference
2008
MicroRNA signatures in genetic subtypes of T-cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe
Bruce Poppe
Nadine Van Roy
Tom Taghon
Jean Plum
B Cauwelier
D Selleslag
P Heimann
P Vandenberghe
N Dastugue
et al.
C3
Conference
2008
Minimal residual disease detection at day 35 in childhood acute lymphoblastic leukemia: Which technique(s) to use?
Katrien Swerts
Barbara De Moerloose
B DENYS
M BAKKUS
Bruno Verhasselt
Yves Benoit
Jan Philippé
C3
Conference
2008
Retrospective evaluation of EBV viremia after pediatric allogeneic hematopoietic stem cell transplantation: single-centre experience.
Maria Bordon Cueto De Braem
E Padalko
Els Vandecruys
JORIS VERLOOY
Barbara De Moerloose
Veerle Mondelaers
Yves Benoit
Genevieve Laureys
Catharina Dhooge
C3
Conference
2008
Surveillance of cytomegalovirus (CMV) DNAemia in pediatric allogeneic stem cell transplantation : incidence and outcome of CMV infection and disease
Maria Bordon Cueto De Braem
S Bravo
L Van Renterghem
Barbara De Moerloose
Yves Benoit
Genevieve Laureys
Catharina Dhooge
A1
Journal Article
in
TRANSPLANT INFECTIOUS DISEASE
2008
Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.
Barbara De Moerloose
Katrien Swerts
M BAKKUS
A UYTTEBROECK
N BOECKX
P VANDENBERGHE
Bruno Verhasselt
A VAN DAMME
C DEMANET
Jan Philippé
et al.
C3
Conference
2008
Which technique(s) to use when studying minimal residual disease at day 35 in childhood acute lymphoblastic leukemia: a multicenter approach.
Barbara De Moerloose
Katrien Swerts
M Bakkus
A Uyttebroeck
N Boeckx
P Vandenberghe
Bruno Verhasselt
A Van Damme
C Demanet
Yves Benoit
et al.
C3
Conference
2008
2007
Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCR β-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique
Barbara Cauwelier
H Cavé
C Gervais
M Lessard
C Barin
C Perot
J Van den Akker
F Mugneret
C Charrin
MP Pagès
et al.
A1
Journal Article
in
LEUKEMIA
2007
Het project "Koester": een uniek zorgaanbod voor kinderen met een levensbedreigende aandoening
Yves Benoit
Genevieve Laureys
MARIE-JEANNE DE CLERCQ
A VAN PUYVELDE
KRISTIN MATTHEEUWS
ROSA VAN BOXSTAEL
Catharina Dhooge
P DEVOS
JEANNINE SYMOENS
Nathalie Nolf
et al.
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2007
Invasive fungal infections and allogenic stem cell transplantation in children: a single-center retrospective study
Veerle Mondelaers
Maria Bordon Cueto De Braem
Barbara De Moerloose
Els Vandecruys
JORIS VERLOOY
Catharina Dhooge
Genevieve Laureys
Yves Benoit
C3
Conference
2007
Leukemie bij kinderen in de spotlights; verslag van de 18th Annual Meeting of the International BFM Study Group
Barbara De Moerloose
C3
Conference
2007
Pediatric Hematopoietic Stem Cell Transplantation: 5 years evaluation.
Maria Bordon Cueto De Braem
Els Vandecruys
Barbara De Moerloose
JORIS VERLOOY
Catharina Dhooge
Genevieve Laureys
Yves Benoit
C3
Conference
2007
Prognostic value of BCL2L13 expression in childhood B-cell acute lymphoblastic leukaemia
Katrien Swerts
Barbara De Moerloose
Catharina Dhooge
Yves Benoit
Jan Philippé
C3
Conference
2007
2006
Extramedullary relapse after hematopoietic stem cell transplant for acute leukemia in children : 'sanctuary' sites for chemotherapy and unaccessible for graft versus leukemia effect?
Genevieve Laureys
T Radonic
Maria Bordon Cueto De Braem
Barbara De Moerloose
Els Vandecruys
Catharina Dhooge
Yves Benoit
C3
Conference
2006
Potential application of ELAVL4 real-time quantitative reverse transcription-PCR for detection of disseminated neuroblastoma cells
Katrien Swerts
Barbara De Moerloose
Catharina Dhooge
Jo Vandesompele
C HOYOUX
K BEISKE
Yves Benoit
Genevieve Laureys
Jan Philippé
A1
Journal Article
in
CLINICAL CHEMISTRY
2006
Prognostic significance of blasts with/without pleiocytosis in the cerebro-spinal fluid (CSF) of children with acute lymphoblastic leukemia (ALL) treated without cranial irradiation: results of European Organization for Research and Treatment of Cancer (EORTC) children leukemia group study 58881
N Sirvent
S Suciu
X Rialland
A Robert
F Mazingue
F Millot
Barbara De Moerloose
A Ferster
P Rohrlich
L Norton
et al.
C3
Conference
2006
Prognostic significance of multidrug resistance-related proteins in childhood acute lymphoblastic leukaemia
Katrien Swerts
Barbara De Moerloose
Catharina Dhooge
Genevieve Laureys
Yves Benoit
Jan Philippé
A1
Journal Article
in
EUROPEAN JOURNAL OF CANCER
2006
Quality of life and personality aspects of parents and siblings following the death of a child from cancer
Patricia De Vos
JORIS VERLOOY
Barbara De Moerloose
Elke De Bruyne
W Verdickt
Filip De Fruyt
Barbara De Clercq
C3
Conference
2006
Recurrent t(3;17) translocations in AML with EVII rearrangement.
A De Weer
Bruce Poppe
B Cauwelier
Nadine Van Roy
N Dastugue
Barbara De Moerloose
Yves Benoit
Lucien Noens
Anne De Paepe
Franki Speleman
C3
Conference
2006
Recurrent T(3;17)translocations in AML with EVI1 rearrangement
An De Weer
Bruce Poppe
B Cauwelier
Nadine Van Roy
N DASTUGUE
Barbara De Moerloose
Yves Benoit
Lucien Noens
Anne De Paepe
Franki Speleman
C3
Conference
2006
The TCRB-HOXA rearrangement in T-ALL leads to a specific increase of the alternative HOXA10b transcript
B Cauwelier
H CAVÉ
N DASTUGUE
P HEIMANN
H ANTOINE-POIREL
Bruno Verhasselt
Yves Benoit
Barbara De Moerloose
Nadine Van Roy
A HAGEMEIJER
et al.
C3
Conference
2006
Therapeutic efficacy and safety of transfusion of pathogen-inactivated platelets tot pediatric patients
Inge Van haute
Yves Benoit
Maria Bordon Cueto De Braem
Barbara De Moerloose
Els Vandecruys
Sophie Van Lancker
MURIEL VAN VOOREN
Bart Vandekerckhove
C3
Conference
2006
Transiënte erythroblastopenie bij kinderen
Veerle Mondelaers
KATHLEEN HUNNINCK
L Oosterlynck
JOKE VANDUYNSLAGER
Yves Benoit
Barbara De Moerloose
A2
Journal Article
in
Tijdschrift voor Geneeskunde
2006
2005
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
Franki Speleman
Barbara Cauwelier
N DASTUGUE
J COOLS
Bruno Verhasselt
Bruce Poppe
Nadine Van Roy
Jo Vandesompele
C GRAUX
A UYTTEBROECK
et al.
A1
Journal Article
in
LEUKEMIA
2005
Detectie van minimale residuele ziekte bij kinderen met neuroblastoom
Barbara De Moerloose
Katrien Swerts
A4
Journal Article
in
VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË
2005
Extramedullary relapse in patients treated by donor lymphocyte infusion for haematological relapse after allogeneic bone marrow transplant
Maria Bordon Cueto De Braem
Barbara De Moerloose
Els Vandecruys
Catharina Dhooge
Yves Benoit
Genevieve Laureys
C3
Conference
2005
Het prognostisch belang van P-glycoproteïne bij kinderen met acute lymfoblasten leukemie en neuroblastomen
Barbara De Moerloose
A4
Journal Article
in
VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË
2005
HOYA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS
Bruce Poppe
Nurten Yigit
Barbara De Moerloose
Anne De Paepe
Yves Benoit
Franki Speleman
A1
Journal Article
in
CANCER GENETICS AND CYTOGENETICS
2005
Invasive fungal infections after allogeneic stem cell transplantation in children: A single-center retrospective study
Maria Bordon Cueto De Braem
Barbara De Moerloose
Catharina Dhooge
Els Vandecruys
Genevieve Laureys
Yves Benoit
C3
Conference
2005
Loodintoxicatie als gevolg van Pica
A VERSCHELDE
Barbara De Moerloose
Dirk Matthys
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2005
2004
Comparison of two functional flow cytometric assays to assess P-gp activity in acute leukemia
Katrien Swerts
Barbara De Moerloose
Catharina Dhooge
Lucien Noens
Genevieve Laureys
Yves Benoit
Jan Philippé
A1
Journal Article
in
LEUKEMIA & LYMPHOMA
2004
Detection of residual neuroblastoma cells in bone marrow: Comparison of flow cytometry with immunocytochemistry
K SWERTS
Barbara De Moerloose
Catharina Dhooge
B BRICHARD
Yves Benoit
Genevieve Laureys
Jan Philippé
A1
Journal Article
in
CYTOMETRY PART B-CLINICAL CYTOMETRY
2004
Four-color flow cytometric detection of residual neuroblastoma cells
Jan Philippé
Katrien Swerts
Barbara De Moerloose
Catharina Dhooge
Yves Benoit
Genevieve Laureys
C1
Conference
2004
2003
Actuele inzichten en prognostische karakteristieken van het neuroblastoom
Barbara De Moerloose
Katrien Swerts
Genevieve Laureys
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
2003
CNS relapse in a stage 3 neuroblastoma patient
Barbara De Moerloose
VALERIE MEERSSCHAUT
Yves Benoit
Genevieve Laureys
C1
Conference
2003
The combined analysis of P-glycoprotein expression and activity predicts outcome in childhood acute lymphoblastic leukemia
Barbara De Moerloose
Katrien Swerts
Yves Benoit
Genevieve Laureys
Tom Loeys
Jan Philippé
Catharina Dhooge
A1
Journal Article
in
PEDIATRIC HEMATOLOGY AND ONCOLOGY
2003
The quantification of MDR1 transcripts by real-time RT-PCR does not predict drug resistance in childhood acute lymphoblastic leukemia
Katrien Swerts
Barbara De Moerloose
B LEUS
Catharina Dhooge
Genevieve Laureys
Bruno Verhasselt
Yves Benoit
Jan Philippé
C1
Conference
2003
2002
Expression of the multidrug transporter P-glycoprotein is highly correlated with clinical outcome in childhood acute lymphoblastic leukemia: Results of a long-term prospective study.
Catharina Dhooge
Barbara De Moerloose
Genevieve Laureys
A FERSTER
Dirk De Bacquer
Jan Philippé
Juliaan Leroy
Yves Benoit
A1
Journal Article
in
LEUKEMIA & LYMPHOMA
2002
2001
Combined evaluation of P-glycoprotein expression and activity contributes to the identification of children at risk for leukaemic relapse
Barbara De Moerloose
Katrien Swerts
Catharina Dhooge
S STEYAERT
Yves Benoit
Genevieve Laureys
Jan Philippé
C1
Conference
2001
2000
Repetitive analyses of P-glycoprotein in chronic myeloid leukaemia
Barbara De Moerloose
A Muylaert
F Gemmel
Anne Janssens
Bruce Poppe
Catharina Dhooge
Werner Van Hove
Jan Philippé
A1
Journal Article
in
ACTA CLINICA BELGICA
2000
1999
Chromosome 7 short arm deletions and disease progression in CML
Bruce Poppe
H VAN LIMBERGEN
ANN JANSSENS
Nadine Van Roy
Barbara De Moerloose
J PHILLIPE
Anne De Paepe
Fritz Offner
Franki Speleman
C3
Conference
1999
Discrepant flow cytometric expression and function of P-glycoprotein in neuroblastic tumors
Barbara De Moerloose
Catharina Dhooge
Genevieve Laureys
Yves Benoit
M DEMARCHE
C DEVALCK
D PLANTAZ
Juliaan Leroy
Jan Philippé
A1
Journal Article
in
CYTOMETRY
1999
P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia : results of a 6-year prospective study
Catharina Dhooge
Barbara De Moerloose
Genevieve Laureys
Jozef Kint
A Ferster
Dirk De Bacquer
Jan Philippé
Yves Benoit
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
1999
P-Glycoproteine in de aanpak van chemotherapieresistentie.
Barbara De Moerloose
Catharina Dhooge
J PHILIPPE
Yves Benoit
Jozef Kint
Juliaan Leroy
A2
Journal Article
in
TIJDSCHRIFT VOOR GENEESKUNDE
1999
Technetium-99m sestamibi imaging in paediatric neuroblastoma and ganglioneuroma and its relation to P-glycoprotein.
Barbara De Moerloose
C VAN DE WIELE
Catharina Dhooge
Jan Philippé
Franki Speleman
Yves Benoit
Genevieve Laureys
Rudi Dierckx
A1
Journal Article
in
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
1999
1997
Expression of the MDR1 gene product P-glycoprotein in childhood neuroblastoma
Catharina Dhooge
Barbara De Moerloose
Yves Benoit
Nadine Van Roy
Jan Philippé
Genevieve Laureys
A1
Journal Article
in
CANCER
1997
1996
Immunocytochemical and flow cytometric analysis of P-glycoprotein in childhood ALL
Barbara De Moerloose
Jan Philippé
Catharina Dhooge
C3
Conference
1996
1994
Expression of the multidrug transporter, P-glycoprotein, in childhood leukemia: a prospective clinical study
Catharina Dhooge
Barbara De Moerloose
C De Potter
Genevieve Laureys
Yves Benoit
J Leroy
A2
Journal Article
in
INTERNATIONAL JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY
1994