Research Explorer

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Researcher

Annemiek Uvyn

Awards & Distinctions

12 Results

2024

Lysosomal trafficking and degradation of extracellular proteins via multivalent small molecule ligand display on dextran scaffolds

Benoit LouageDemi DefreyneHeleen LauwersJamie De BaereAnnemiek UvynHaixia PengYong ChenBruno De Geest

A1 Journal Article in BIOMACROMOLECULES

2023

Hapten/myristoyl functionalized poly(propyleneimine) dendrimers as potent cell surface recruiters of antibodies for mediating innate immune killing

Annemiek UvynMarle Elisabeth Jacqueline VleugelsBas de WaalAhmed Emad Ibrahim HamoudaShikha DhimanBenoit LouageLorenzo AlbertazziDamya LaouiE. W. MeijerBruno De Geest

A1 Journal Article in ADVANCED MATERIALS

Sequence-defined antibody-recruiting macromolecules

Resat AksakalCorentin TonneauxAnnemiek UvynMathieu FossépréHatice TurgutNezha BadiMathieu SurinBruno De GeestFilip Du Prez

A1 Journal Article in CHEMICAL SCIENCE

Towards a rational design of antibody‐recruiting molecules through a computational microscopy view of their interactions with the target antibody

Annemiek UvynCorentin TonneauxMathieu FossépréAude Ouvrier‐BuffetBruno De GeestMathieu Surin

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2021

Covalent cell surface conjugation of nanoparticles by a combination of metabolic labeling and click chemistry

Alexander LamootAnnemiek UvynSabah KasmiBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalent antibody recruiting molecules as a novel type of cancer immunotherapy

Annemiek UvynBruno De Geest

Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine**

Sonia JangraJana De VriezeAngela ChoiRaveen RathnasingheGabriel LaghlaliAnnemiek UvynSimon Van HerckLutz NuhnKim DeswarteZifu Zhong et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2020

Multivalent antibody-recruiting macromolecules : linking increased binding affinity with enhanced innate immune killing

Annemiek UvynBruno De Geest

A1 Journal Article in CHEMBIOCHEM

Poly(2-methyl-2-oxazoline) conjugates with doxorubicin : from synthesis of high drug loading water-soluble constructs to in vitro anti-cancer properties

Ondrej SedlacekAlexandra Van DriesscheAnnemiek UvynBruno De GeestRichard Hoogenboom

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Sterilizing immunity against SARS-CoV-2 infection in mice by a single-shot and modified imidazoquinoline TLR7/8 agonist-adjuvanted recombinant spike protein vaccine

Sonia JangraJana De VriezeAngela ChoiRaveen RathnasingheGabriel LaghlaliAnnemiek UvynSimon Van HerckLutz NuhnKim DeswarteZifu Zhong et al.

2019

Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells

Annemiek UvynRuben De CoenOlivier De WeverKim DeswarteBart LambrechtBruno De Geest

A1 Journal Article in CHEMICAL COMMUNICATIONS

Efficient innate immune killing of cancer cells triggered by cell-surface anchoring of multivalent antibody-recruiting polymers

Annemiek UvynRuben De CoenMandy GruijsCees W. TukJana De VriezeMarjolein van EgmondBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION