Research Explorer

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Researcher

Annelies Demeyer

Awards & Distinctions

16 Results

2025

Role of MALT1 substrate cleavage in immune regulation : insights from a mouse gene targeting approach

Ioannis SkordosRudi BeyaertAnnelies DemeyerJens Staal

2023

Exploring immune checkpoint proteins : novel targets in vitiligo research

Arno BelpaireNanja van GeelAnnelies DemeyerReinhart Speeckaert

Normal lymphocyte homeostasis and function in MALT1 protease-resistant HOIL-1 knock-in mice

Ioannis SkordosYasmine DriegeMira HaegmanMarja KreikeJens StaalAnnelies DemeyerRudi Beyaert

A1 Journal Article in FEBS JOURNAL

2021

Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry

Ioannis SkordosAnnelies DemeyerRudi Beyaert

A2 Journal Article in STAR PROTOCOLS

Clinical relevance of serum Kyn/Trp ratio and basal and IFN gamma-upregulated IDO1 expression in peripheral monocytes in early stage melanoma

Annabel MeiresonLiesbeth FerdinandeMarc HaspeslaghBenjamin HennartDelphine AllorgePiet OstNora SundahlMathieu SpaasAnnelies DemeyerLieve Brochez

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Immune monitoring in melanoma and urothelial cancer patients treated with anti-PD-1 immunotherapy and SBRT discloses tumor specific immune signatures

Annabel MeiresonSimon TavernierSofie Van GassenNora SundahlAnnelies DemeyerMathieu SpaasVibeke KruseLiesbeth FerdinandeJo Van DorpeBenjamin Hennart et al.

A1 Journal Article in CANCERS

2020

Fragility can be a good thing in cancer

Annelies DemeyerRudi Beyaert

Editorial material

Long-term MALT1 inhibition in adult mice without severe systemic autoimmunity

Annelies DemeyerYasmine DriegeIoannis SkordosJulie CoudenysKelly LemeireDirk ElewautJens StaalRudi Beyaert

A1 Journal Article in ISCIENCE

2019

Deletion of mucosa-associated lymphoid tissue lymphoma translocation protein 1 in mouse T cells protects against development of autoimmune arthritis but leads to spontaneous osteoporosis

Elisabeth GilisDjoere GaublommeJens StaalKoen VenkenMaarten DhaenensStijn LambrechtJulie CoudenysTine DecruyNadia SchryversYasmine Driege et al.

A1 Journal Article in ARTHRITIS & RHEUMATOLOGY

MALT1 proteolytic activity suppresses autoimmunity in a T cell intrinsic manner

Annelies DemeyerIoannis SkordosYasmine DriegeMarja KreikeTino HochepiedMathijs BaensJens StaalRudi Beyaert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

MALT1-deficient mice develop atopic-like dermatitis upon aging

Annelies DemeyerElien Van NuffelGriet BaudeletYasmine DriegeMarja KreikeDavid MuyllaertJens StaalRudi Beyaert

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2016

Functional characterization of the paracaspase MALT1 in T cells

Annelies DemeyerRudi BeyaertJens Staal

Targeting MALT1 proteolytic activity in immunity, inflammation and disease: good or bad?

Annelies DemeyerJens StaalRudi Beyaert

A1 Journal Article in TRENDS IN MOLECULAR MEDICINE

2014

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis

Conor Mc GuireLynn EltonPeter WieghoferJens StaalSofie VoetAnnelies DemeyerDaniel NagelDaniel KrappmannMarco PrinzRudi Beyaert et al.

A1 Journal Article in JOURNAL OF NEUROINFLAMMATION

2011

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1

Jens StaalYasmine DriegeTine BekaertAnnelies DemeyerDavid MuyllaertPetra Van DammeKris GevaertRudi Beyaert

A1 Journal Article in EMBO JOURNAL

2010

Cleavage by MALT1 induces cytosolic release of A20

Claire MalinverniAdeline UnterreinerJens StaalAnnelies DemeyerMarion GalaupMarcel LuytenRudi BeyaertFrédéric Bornancin

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS