Research Explorer

Project

Role of microRNAs in the pathogenesis of obstructive airway diseases
Code
05U40516
Duration
15 February 2017 → 14 February 2022
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Respiratory medicine
Keywords
pathogenesis microRNA
 
Project description
 

Genetic predisposition and the environment play a crucial role in the pathogenesis of obstructive airway diseases, such as asthma and COPD. This translational project will unravel the contribution of epigenetic changes, in particular of microRNAs, in the pathogenesis of both diseases using expression analyses, in vitro studies on human cell cultures and in vivo research on murine models of asthma en COPD.