Starting work is challenging and requires adjustment. This adaptation can run difficult in demanding work environments, such as within health care, and pose risk of burnout. Burnout in young health professionals has not been adequately studied. This project surveys a cohort of health professionals after graduation (baseline) and over the following three years. We expect to distinguish diverse groups with differential risk of burnout. We will also examine the role of job demands and resources on the relationship between burnout and job outcomes (e.g., turnover, absenteeism). We will further explore the impact of professional culture and developmental challenges on the development of burnout. This project is highly innovative due to the longitudinal nature of the study whereby employees can be followed throughout their early career. Qualitative research provides input for developing early interventions tailored to health professionals.