Project

MicroRNA's in neuroblastoma

Duration
01 January 2008 → 31 December 2010
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
    • Molecular and cell biology
    • Morphological sciences
    • Oncology
Keywords
neuroblastoma methylation micro-RNA
 
Project description

The main goal of this project is to gain insight into the epigenetic alterations that contribute to neuroblastoma (NB) development and progression. We aim at identifying genes and signaling pathways that are disturbed in the different NB subtypes with special attention for possible druggable targets. Moreover, attention will go to an improved prognostic stratification for NB patients and the selection of NB patients who qualify for such new treatment.