Project

Importance of enterohaemorrhagic Escherichia coli in Iran and new tools for controlling spread from ruminants to man

Duration
01 October 2007 → 30 September 2009
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Animal biology
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Immunology
    • Laboratory medicine
    • Microbiology
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural, veterinary and food sciences
Keywords
ELISA EHEC ruminants lactoferrin
 
Project description

EHEC is an important food-borne pathogen, that can cause a fatal infection of humans and especially of children under 5 years of age. Ruminants are the most important reservoir of EHEC, since infection of ruminants does not cause diseases and since ruminants can excrete EHEC via the faeces during months. This project aims to assess the importance of EHEC as a food-borne zoonosis in Iran, to develop a serological screening assay that will allow to monitor the occurrence of EHEC infections within cattle and sheep herds and to test if the natural antimicrobial lactoferrin can be used to decrease or inhibit EHEC excretion by ruminants.