Research Explorer

Project

New strategy for biodetection of explosive nitro-chemicals in environmental samples
Code
42I00107
Duration
20 January 2007 → 19 January 2009
Funding
International funding: global institutions
Research disciplines
  • Natural sciences
    • Analytical chemistry
    • Sustainable chemistry
    • Aquatic sciences, challenges and pollution
    • Environmental science and management
  • Medical and health sciences
    • Pharmaceutical analysis and quality assurance
Keywords
ELISA TNT immunoassays PFIA
 
Project description
 

Rapid immunoanalytical methods for TNT and related compounds will be designed. Using the antibody as "principle active force" of the analytical methods, the immunoassays allow reaching high specificity and sensititivy of the analyte determination without long-term preliminary purification of the samples. Polarization fluoroimmunoassay (PFIA), magnetoimmunnoassays (m-IA), enzyme-linked immunosorbent assay (ELISA) and clean-up tandem immunoassay will be developed and optimized.