Skin interaction of the cyclic depsipeptide mycotoxins

01 October 2012 → 30 September 2016
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Dermatology
    • Medical biochemistry and metabolism
    • Dermatology
    • Medical biochemistry and metabolism
    • Public health care
    • Public health sciences
    • Public health services
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
    • Dermatology
    • Medical biochemistry and metabolism
risk assessment transdermal cyclic depsipeptides skin mycotoxin pharmaceutics
Project description

This research project quantitatively characterises the interaction of cyclic depsipeptides (CDP) with human skin using ex-vivo in-vitro FDC experiments. This knwoledge is required for the global mycotoxin risk assessment due to skin-contact of contaminated cosmeceuticals, food, feed, indoor surfaces and airborne particles, but also for the development of topically applied new CDP-drugs, treating dermatological or systemic diseases after transdermal penetration.