Project

Growth, virulence expression and toxin production of Bacillus cereus in the small intestine

Code
01J02108
Duration
01 January 2008 → 31 October 2012
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
bacilus cereus SHIME toxines small intestine PCR
 
Project description

Taking into account the biodiversity of foodborne B. cereus, information will be gained with regard to growth kinetics, gene expression and toxin production in the gastro-intestinal ecological environment using batch cultures and a Simulator of the Human Intestinal Microbial Ecosystem (SHIME). Detection of toxin production will be elaborated via HPCL-MS, real-time PCR performed for monitoring B. cereus cells and gene expression.