Project

Growth, virulence expression and toxin production of Bacillus cereus in the small intestine

Code
01J02108
Looptijd
01-01-2008 → 31-10-2012
Financiering
Regional and community funding: Special Research Fund
Onderzoeksdisciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Trefwoorden
PCR toxines SHIME dunne darm bacillus cereus
 
Projectomschrijving
 

Taking into account the biodiversity of foodborne B. cereus, information will be gained with regard to growth kinetics, gene expression and toxin production in the gastro-intestinal ecological environment using batch cultures and a Simulator of the Human Intestinal Microbial Ecosystem (SHIME). Detection of toxin production will be elaborated via HPCL-MS, real-time PCR performed for monitoring B. cereus cells and gene expression.