Research Explorer

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Project

The barrier role of the vitreoretinal interface toward intravitreal injected proteins, viruses and siRNA nanoparticles: ex vivo bovine screening models and siRNA nanoparticle design.

Outputs & Impact

Publications & research data ( 6 )

ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery

Karen PeynshaertHelena VanlucheneKaat De ClerckAn-Katrien MinnaertMorgane VerhoevenNoémie GouspillouNezahat BostanToshio HisatomiGeraldine AccouFélix Sauvage et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Bram BogaertFelix SauvageRoberta GuagliardoCristina Muntean[missing] Van Phuc NguyenEline PottieMike WelsAn-Katrien MinnaertRiet De RyckeQiangbing Yang et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy

An-Katrien MinnaertLoes van SchieHendrik GrootaertJonas HimpeSimon DevosWannes WeytsHerlinde De KeersmaeckerKevin BraeckmansElisabeth Van AkenJoris Delanghe et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Together is better : mRNA co‐encapsulation in lipoplexes is required to obtain ratiometric co‐delivery and protein expression on the single cell level

Heyang ZhangJeroen BussmannFlorian H. HuhnkeJoke DevoldereAn-Katrien MinnaertWim JiskootFriedhelm SerwaneJoachim SpatzMagnus RödingStefaan De Smedt et al.

A1 Journal Article in ADVANCED SCIENCE

Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across

An-Katrien MinnaertHelena VanlucheneRein VerbekeIne LentackerStefaan De SmedtKoen RaemdonckNiek SandersKatrien Remaut

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Vaccinia virus protein B18R : influence on mRNA immunogenicity and translation upon non-viral delivery in different ocular cell types

An-Katrien MinnaertJoke DevoldereKaren PeynshaertLaure VercruysseStefaan De SmedtKatrien Remaut

A1 Journal Article in PHARMACEUTICS

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )