Research Explorer

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Project

Computational biomechanics as a tool for personalised medicine

Outputs and Outcomes

Publications

Image-guided patient-specific prediction of interstitial fluid flow and drug transport in solid tumors

Hooman SalavatiPim PullensCharlotte DebbautWim Ceelen

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Simplification strategies for a patient-specific CFD model of particle transport during liver radioembolization

Tim BombernaGeert MaleuxCharlotte Debbaut

A1 Journal Article in COMPUTERS IN BIOLOGY AND MEDICINE

Adaptive design of experiments to fit surrogate Gaussian process regression models allows fast sensitivity analysis of the input waveform for patient-specific 3D CFD models of liver radioembolization

Tim BombernaGeert MaleuxCharlotte Debbaut

A1 Journal Article in COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Effect of interstitial fluid pressure on shear wave elastography : an experimental and computational study

Ariana CihanKristýna HolkováLuxi WeiHendrik J VosCharlotte DebbautAnnette CaenenPatrick Segers

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Spatiotemporal analysis of particle spread to assess the hybrid particle-flow CFD model of radioembolization of HCC tumors

Tim BombernaSaar VermijsLawrence BonneChris VerslypeGeert MaleuxCharlotte Debbaut

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

First‐in‐human real‐time AI‐assisted instrument deocclusion during augmented reality robotic surgery

Jasper HofmanPieter De BackerIlaria ManghiJente SimoensRuben De GrooteHannes Van Den BosscheMathieu D'HondtTim OosterlinckJulie LippensCharles Van PraetFederica FerragutiCharlotte DebbautZhijin LiOliver KutterAlexandre MottrieKarel Decaestecker et al.

A2 Journal Article in HEALTHCARE TECHNOLOGY LETTERS

Truncation strategies for personalized CFD models of selective liver radioembolization

Tim BombernaSaar VermijsChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

Computational fluids dynamics to investigate the impact of injection timing and location on microsphere and microbubble distribution in a simplified hepatic arterial tree

Tim BombernaNathalie SaikaliRomaine KunstHadi MirgolbabaeeErik Groot JebbinkGeert MaleuxCharlotte Debbaut

Computational modelling of liver hemodynamics and intrahepatic particle transport

Charlotte DebbautTim Bomberna

The impact of hepatic arterial tree complexity on microparticle transport in computational fluids dynamics simulations of radioembolization for hepatocellular carcinoma

Tim BombernaSaar VermijsMaryse LejolyChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

The impact of injection timing, injection velocity and inflow waveform on microsphere transport during liver radioembolization

Tim BombernaSaar VermijsChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

The future of preoperative planning for liver cancer : from CT-scan in the 20th century to computational model in the 21st century

Tim BombernaCharlotte Debbaut

Assessment of hepatic arterial hemodynamics with 4D flow MRI : in vitro analysis of motion and spatial resolution related error and in vivo feasibility study in 20 volunteers

Ivan P. DimovCyril TousNing LiMaxime BaratTim BombernaCharlotte DebbautNing JinGerald MoranAn TangGilles Soulez

A1 Journal Article in EUROPEAN RADIOLOGY

A hybrid particle-flow CFD modeling approach in truncated hepatic arterial trees for liver radioembolization : a patient-specific case study

Tim BombernaSaar VermijsMaryse LejolyChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

A1 Journal Article in FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

The impact of catheter location on tumor dose distribution for liver cancer radioembolization

Tim BombernaSaar VermijsChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

Numerical modelling in support of locoregional drug delivery during transarterial therapies for liver cancer

Charlotte DebbautTim Bomberna

Bookchapter in Modelling of mass transport processes in biological media

Proof-of-concept CFD model to improve hepatic arterial tree recellularization protocols

Tim BombernaGhazal Adeli KoudehiPedro BaptistaCharlotte Debbaut

Comparing time-efficient particle release maps for liver tumor targeting with embolizing microparticles

Tim BombernaGeert MaleuxCharlotte Debbaut

Evaluating the impact of catheter type on local hemodynamics to improve transarterial liver cancer treatments

Tim BombernaGhazal Adeli KoudehiChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

The impact of injection timing and location on microparticle delivery for tumor targeting in a patient-specific liver

Tim BombernaChris VerslypeLawrence BonneGeert MaleuxCharlotte Debbaut

Transarterial drug delivery for liver cancer : numerical simulations and experimental validation of particle distribution in patient-specific livers

Tim BombernaGhazal Adeli KoudehiCharlotte ClaereboutChris VerslypeGeert MaleuxCharlotte Debbaut

A1 Journal Article in EXPERT OPINION ON DRUG DELIVERY

Computational fluid dynamics as a tool for patient-specific injection planning of transarterial therapies for hepatocellular carcinoma

Tim BombernaChris VerslypeGeert MaleuxCharlotte Debbaut

Locoregional drug delivery for liver cancer : the impact of tumor burden on the particle distribution in a patient-specific liver

Tim BombernaGhazal Adeli KoudehiGeert MaleuxCharlotte Debbaut

Targeted drug delivery for liver cancer : modelling the impact of cancer burden on the particle distribution

Tim BombernaGhazal Adeli KoudehiPatrick SegersCharlotte Debbaut

Targeted drug delivery for liver cancer : can we steer microparticles towards tumor tissue?

Tim BombernaGhazal Adeli KoudehiPatrick SegersCharlotte Debbaut

Targeted drug delivery for liver cancer : the impact of cancer burden on the particle distribution in a patient-specific geometry

Tim BombernaGhazal Adeli KoudehiPatrick SegersCharlotte Debbaut