Project

Calculating permeability of drugs through liposomal membranes

Code
01CD9623
Looptijd
06-12-2023 → 05-06-2024
Financiering
Regional and community funding: Special Research Fund
Promotor
Onderzoeksdisciplines
  • Natural sciences
    • Modelling and simulation
    • Molecular physics
    • Computational physics
    • (Bio)molecular modelling and design
    • Lipids
Trefwoorden
permeabiliteit lipide Grofkorrelige moleculaire dynamica gebogen membraan medicijn vrije energie
 
Projectomschrijving
Liposomes are considered as advanced drug delivery systems for cancer treatment. The passive permeability of the drug through the liposome's membrane is a crucial factor for timely drug delivery. Systems with different composition and curvature are simulated using coarse-grained molecular dynamics (MD), in order to examine their effect on the permeability.