Project

Design of Enabling Regenerative Materials

Acronym
DERMA
Code
41U06716
Duration
01 September 2016 → 30 November 2020
Funding
European funding: various
Research disciplines
  • Natural sciences
    • Macromolecular and materials chemistry not elsewhere classified
Keywords
Regenerative Materials
Other information
 
Project description

DERMA will focus on developing new healthcare technologies to improve the quality of life of the ageing population –a key EU priority (Art. 18 EU reg. 1303/2013). We will advance capabilities in the management of dermal ulcers and the related skin condition, peristomal inflammation, with focus on our established technologies using marine materials. By 2025 more than 20% of Europeans will be 65 or older, a vulnerable group in relation to illness. This is a crossborder phenomenon that will challenge healthcare providers. Ulceration of the extremities of this group is a major societal challenge. Moreover, the presence of diabetes, cardiovascular disease, fungating tumours and longterm immobilisation, exposes all age groups to dermal ulceration. Dermal ulcers account for 24% of the total EU healthcare budget. Venous leg ulceration affects 1% of the EU population with costs of €10,000 per patient (EU total is €6.5 billion per annum). There are 700,000 ostomates in the EU who face the problem of inflammation, infection and pain of the peristomal (surrounding) skin. DERMA will apply its technologies for innovative solutions for the management and treatment of such dermal skin conditions. The wound care market is worth €16 billion worldwide. The expected developed dressings will be more effective and require less frequent replacement and thus will reduce wound management costs by an estimated 30%, with cost savings in excess of the ERDF contribution.

 
Role of Ghent University
The Polymer Chemistry & Biomaterials Group (Profs. Peter Dubruel and Sandra Van Vlierberghe) is joining forces with the Department of Plastic and Reconstructive Surgery (Prof. Stan Monstrey) towards the development of enabling technologies for improved wound management. Ghent University will select and develop the wound dressing building blocks. In addition to polymer synthesis, Ghent University will also perform the functionalization of biopolymers with crosslinkable and/or odour-adsorbing moieties followed by an in-depth physico-chemical characterization. The materials developed will be processed through co-extrusion electrospinning. UGent will also contribute to the design and development of smart wound dressings with diagnostic capabilities.
 
 
Disclaimer
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Regional Development Fund, ERDF. Neither the European Union nor the authority can be held responsible for any use the may be made of the information contained therein.