Research Explorer

Project

Study of the stimuli required for the generation and maintenance of hematopoietic stem cells from humanpluripotent stem cells
Code
3G083510
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Systems biology
  • Medical and health sciences
    • Hematology
    • Laboratory medicine
    • Hematology
    • Laboratory medicine
    • Hematology
    • Laboratory medicine
Keywords
hematopoiesis induced pluripotent stem cells
 
Project description

The generation of hematopoietic stem cells from pluripotent stem cells will be studied. To this end, reporter lines will be generated for PU.1, MEIS1 and CD3epsilon. Subsequently hematopoiesis from PSC will be studied in the niche using confocal microscopy.