Project

Bridging the gap between the physiological and therapeutic roles of mesenchymal stem cells

Duration
01 February 2019 → Ongoing
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Stem cell biology
    • Cellular interactions and extracellular matrix
    • Medical genomics
Keywords
Stem cell therapy equine tendon
 
Project description

To unlock the therapeutic potential of mesenchymal stem cells (MSCs), we will focus in this research proposal on the cross-talk between equine MSCs and tenocytes using in vitro cultures mimicking tendon lesions in the horse, as this setting allows us to study the three main regenerative mechanisms of MSCs: secretion of paracrine factors, cell differentiation and immune modulation.