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Project

Mechanisms of ferroptosis mediated immunoregulation

Outputs & impact

Publicaties & datasets ( 12 )

TAB2 controls a TAK1-independent cell death checkpoint at the level of TNFR1 complex II in the TNF pathway

Tom DelangheMike VadiAnnelore HaemsLisa WijnsInge BruggemanJon HuygheDario PriemPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Ripk1 is critical for preserving effector regulatory T cells and the suppressive transcriptional program in regulatory T cells

Carlos Plaza-SirventHannah SturmMaximilian K. NockeFatemeh GhorbaniClara BessenMarina C. Greweling-PilsStefan FloessJana NiemzJelle HuysentruytPeter Tougaard et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Development and validation of a high-throughput screening pipeline of compound libraries to target EMT

Sven JonckheereJoachim TaminauJamie AdamsJef HaerinckJordy De ConinckJeroen VerstappeKato De ClercqEvelien PeetersAlexander GheldofEva De Smedt et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Enhancing anti-tumor immunity through intratumoral combination therapy with amphiphilic conjugates of oxaliplatin and imidazoquinoline TLR7/8 agonist

Hanne VerschuereSabah KasmiLutz NuhnSènan Mickaël D'AlmeidaQiwen ZhuZifu ZhongSandy Adjemian CataniBenoit LouageJana De VriezeHaijun Yu et al.

A1 Journal Article in RSC ADVANCES

Ferroptosis in health and disease

Carsten BerndtHamed AlborziniaVera Skafar AmenScott AytonUladzimir BarayeuAlexander BarteltHülya BayirChristina M BebberKivanc BirsoyJan P Böttcher et al.

A1 Journal Article in REDOX BIOLOGY

NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

Yves DondelingerDario PriemJon HuygheTom DelanghePeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis

Benjamin CappeMike VadiEliza SackLudivine WacheulBruno VerstraetenSara DufourJulien FranckWei XieFrancis ImpensAn Hendrix et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression

Emily Van SanAngela DebruyneGeraldine VeeckmansYulia Y. Y. TyurinaVladimir A. A. TyurinHao ZhengSze Men ChoiKoen AugustynsGeert van LooBernhard Michalke et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of nemorosone-induced ferroptosis in cancer cells

Roberto Fernández-AcostaBehrouz HassanniaJurgen CaroenBartosz WiernickiDaniel Alvarez-AlminaqueBruno VerstraetenJohan Van der EyckenPeter VandenabeeleTom Vanden BergheGilberto L. Pardo-Andreu

A1 Journal Article in CELLS

Pore-forming proteins as drivers of membrane permeabilization in cell death pathways

Peter VandenabeeleGeert BultynckSavvas Savvides

A1 Journal Article in NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

Bartosz WiernickiSophia MaschalidiJonathan PinneySandy Adjemian CataniTom Vanden BergheKodi RavichandranPeter Vandenabeele

A1 Journal Article in NATURE COMMUNICATIONS

Targeting ferroptosis protects against experimental (multi)organ dysfunction and death

Samya Van CoillieEmily Van SanInes GoetschalckxBartosz WiernickiBanibrata MukhopadhyayWulf TonnusSze Men ChoiRia RoelandtCatalina DumitrascuLudwig Lamberts et al.

A1 Journal Article in NATURE COMMUNICATIONS

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