Code
01D26115
Duration
01 October 2015 → 09 March 2020
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Natural sciences
- Animal biology
-
Social sciences
- Biological and physiological psychology
- Clinical and counselling psychology
- Cognitive science and intelligent systems
- Developmental psychology and ageing
- Other psychology and cognitive sciences
-
Medical and health sciences
- Medical imaging and therapy
- Neurosciences
- Psychiatry and psychotherapy
- Medical imaging and therapy
- Neurosciences
- Psychiatry and psychotherapy
- Nursing
- Other paramedical sciences
- Medical imaging and therapy
- Neurosciences
- Psychiatry and psychotherapy
-
Agricultural and food sciences
- Veterinary medicine
- Other veterinary sciences
- Other agricultural and food sciences
Keywords
dog
functional imaging
SPECT
depression
hond
biomarkers
ketamine
Project description
Major depressive disorder is a costly brain disorder in Europe. Limitation of existing therapies is the low response rate and lag of onset, which increases suicide risk. Low dose ketamine seems promising in this respect. A dog model will be used to investigate the effect of ketamine on the serotonergic system, brain perfusion and inflammatory biomarkers in dogs.