Research Explorer

Project

Receptor-based anti-adhesive molecules as prophylactic treatment of F4+ E. coli and F18+ E. coli infections in young piglets.
Code
17807810
Duration
01 July 2010 → 14 November 2012
Funding
Regional and community funding: IWT/VLAIO
Promotor
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
prophylactic treatment F4/18+ E. coli F4- and F18 receptor
 
Project description

In this project, we will firstly develop a screening system for inhibitors of F4+ and F18+ E. coli adhesion to intestinal receptors. Secondly, we aim to develop a prophylactic treatment against F4+ and F18+ E. coli infections in pigs. Hereto, we will use our fundamental knowledge of the F4- and F18 receptors involved in adherence.