Project

The effects of Nasonia vitripennis venom: pathways and expression profiles in the host Sarcophaga crassipalpis and the human celline HEK293

Code
01DI0612
Duration
01 September 2012 → 31 July 2014
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • Biochemistry and metabolism
    • General biology
    • Microbiology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Morphological sciences
    • Medical biochemistry and metabolism
    • Morphological sciences
    • Medical biochemistry and metabolism
    • Morphological sciences
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
venom and pathways parasitoïd wasps Nasonia vitripennis
 
Project description

The parasitoid wasp Nasonia vitripennis can infect a broad range of hosts (flies) and has a known venom composition. This research will determine which pathways the venom can affect in both the host Sarcophaga crassipalpis and the human celline HEK293, and which venom compounds are responsible for these processes. This will be investigated using microarrays, FACS, reporter arrays and QPCR.