Research Explorer

Project

Interactome analysis of the appendage domains belonging to the endocytic adaptor complexes in plants.
Code
01CD03524
Duration
01 November 2024 → 30 April 2025
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Membrane structure and transport
    • Plant biochemistry
    • Plant cell and molecular biology
    • Interactomics
Keywords
Endocytosis Interactomics Cell Biology
 
Project description
 Clathrin-mediated endocytosis is essential for modulating plasma membrane protein abundance. The ADAPTOR PROTEIN2 COMPLEX and the TPLATE COMPLEX have a prominent role in plant endocytosis. Despite structural similarities, these complexes differ in their appendage domains, which likely function as interaction hubs. This project aims to compare the interactomes of the appendage domains and to characterize novel endocytic players, including regulators of endocytosis.