Research Explorer

Project

Human liver disease: study of the hepatic stem cells and their niche and development of novel model systems
Code
120C02512
Duration
01 April 2012 → 31 December 2017
Funding
Federal funding: various
Research disciplines
  • Natural sciences
    • Genetics
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Gynaecology and obstetrics
    • Immunology
    • Laboratory medicine
    • Molecular and cell biology
    • Morphological sciences
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Gastro-enterology and hepatology
    • Gynaecology and obstetrics
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Molecular and cell biology
    • Morphological sciences
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Other paramedical sciences
    • Gastro-enterology and hepatology
    • Gynaecology and obstetrics
    • Immunology
    • Laboratory medicine
    • Molecular and cell biology
    • Morphological sciences
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
Keywords
HCV hepatic stem cell HBV liver disease cancer animal model
 
Project description

this project wishes to shed more light on the role of the hepatic stem cell in the genesis and evolution of a series of liver diseases such as liver cancer (hepatocellular carcinoma), liver cirrhosis, liver steatosis, and chronic infections of the liver caused by hepatitis B (HBV) and hepatitis C virus (HCV). In addition the IUAP consortium wishes to develop novel in vivo and in vitro models to studies these aforementioned liver diseases.