Injectable gel as a solution to minimize seroma formation

Gel in the pocket
15 April 2023 → 14 April 2024
Regional and community funding: Industrial Research Fund
Research disciplines
  • Medical and health sciences
    • Oncology not elsewhere classified
    • Tissue engineering
    • Tissue engineering
  • Engineering and technology
    • Biomaterials
    • Polymeric materials not elsewhere classified
  • Agricultural and food sciences
    • Veterinary surgery
Vertinary medicine Hydrogel Seroma Human medicine Polymers Minimillay invasive Injectable
Project description

Gelinject is an injectable hydrogel, originally developed to be applied in the human health market, to improve minimally invasive breast reconstruction by lipofilling. Recently, a medical need within the veterinary market was brought to our attention - where Gelinject can provide an answer to - namely the need for a solution to minimize post-operative seroma formation. Seroma is an abnormal collection of serous fluid within the tissues of the body and is a common postoperative complication, especially in dogs that undergo major surgery. To answer this unmet clinical need for a seroma preventative, a biocompatible and easy to apply biomaterial is desired.  Gelinject could be injected into the wound bed to act as both a space filler and a bio-adhesive, in order to reduce fluid accumulation in the pocket. This project aims to (1) further optimize the product for seroma prevention indication and (2) to deliver an industry/clinically-relevant in vivo proof-of-concept, which will allow us to initiate a broader valorization trajectory for Gelinject - beyond the human health market – in veterinary medicine.