Research Explorer

Project

Development of an oral vaccine to protect pigs against postweaning diarrhoea caused by F4+ enterotoxigenic EScherichia coli
Code
17809108
Duration
01 February 2008 → 31 January 2010
Funding
Regional and community funding: IWT/VLAIO
Promotor
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Microbiology
    • Immunology
Keywords
pigs postweaning diarrhoea oral vaccination
 
Project description
 

In this project, an oral vaccine will be developed to protect pigs against F4+ E. coli induced postweaning diarrhoea. Therefore, the F4 protein or DNA will be encapsulated in nanoparticles to prevent gastro-intestinal degradation and specific lectins will be used to promote uptake through the epithelial barrier via enterocytes or M cells.