The main expertise of the group consists of developing computational methods for outstanding problems in systems biology and systems genetics, hereby anticipating on emerging technologies and their applications. Hereto the group combines advanced statistics, AI and data mining, with the proper biological assumptions. My group’s expertise is in developing conceptually innovative solutions for underdetermined data analysis problems by reducing the complexity in a biologically motivated way or by using prior information. We are currently working on applications in clonal systems (bacteria and cancer) and have in this context an ongoing research line in i) the context of digital pathology, ii) biomarker identification and drug target prioritization. The basis financing will be used to guarantee the continuation of the ongoing projects and the exact topic will be determined by the outcome of applied funding.