Project

Development of a 3D horse oviduct: The solution for equine in vitro fertilization?

Code
3E010616
Duration
01 October 2016 → 30 September 2019
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Animal biology
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural, veterinary and food sciences
Keywords
3D-oviduct model horse sperm capacitation
 
Project description

Since equine fertilization takes place in the oviduct, mimicking the oviductal environment is a logical approach to induce sperm capacitation and to achieve fertilization in vitro. We aim to advance further on an equine 3D cell culture system in which oviduct epithelial cell differentiation is re-established to mimic more closely the physiological environment of the oviduct.