Project

Influence of gastric banding and exercise training on the expression of "Sterol regulatory element-binding proteins" (SREBPs) in the skeletal muscle and his association to intramyocitic triglycerides in morbid obese patients

Duration
01 January 2007 → 31 August 2010
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Orthopaedics
    • Physiology
    • Gastro-enterology and hepatology
    • Orthopaedics
    • Physiology
    • Human movement and sports sciences
    • Rehabilitation sciences
    • Gastro-enterology and hepatology
    • Orthopaedics
    • Physiology
Keywords
gastric banding combined exercise training obesity intramyocitic triglycerides SREBP
 
Project description

The mechanisms of the increased intramyocitic triglycerides (IMTG) in insulin resistance and exercise training are not known. A possible pathway could be found in the expression of SREBPs. The purpose of this study is to investigate the effect of gastric banding and exercise training on the expression of SREBPs and its relation to IMTG content in morbidly obese patients.