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Project

Disturbance of the cytoskeleton-plasmamembrane interactions results in intercalated disc malformation and induces cardiomyopathy

Output en outcomes

Code

01N00616

Looptijd

01-01-2016 → 31-10-2020

Financiering

Regional and community funding: Special Research Fund

Promotor

Jolanda van Hengel

Onderzoeksdisciplines

Medical and health sciences
- Cardiology

Trefwoorden

cel-cel interacties cardiomyopathie cytoskelet

Projectomschrijving

Arrhythmogenic Ventricular Cardiomyopathy (AVC) is a genetic, progressive heart condition with abnormal heart rhythm and malfunction of the ventricles. AVC is often caused by mutations in proteins belonging to the areae compositae localized at the intercalated disc. Crucial is the link with the cytoskeleton. This project aims to gain more insights into this link and its contribution to cell-cell interactions and mechanotransduction

English

Dutch

English

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