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Project

Revisiting the function and the mechanisms of action of TNF during DSS colitis in conditions of littermate-controlled normalized gut microbiota composition

Information

Project Team

Organisations

Outputs and Outcomes

Publications

The autoinflammation-associated NLRC4<SUP>V341A</SUP> mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice

Elien EeckhoutTomoko AsaokaHanne Van GorpDieter DemonCharlotte Girard-Guyonvarc'hVanessa AndriesLars VereeckeCem GabayMohamed LamkanfiGeert van LooAndy Wullaert et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2023

Investigating the role of gastrointestinal inflammasome responses during infection and autoinflammation

Elien EeckhoutAndy Wullaert

Dissertation

2023

Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection

Elien EeckhoutLisa HamerlinckVeronique JonckheerePetra Van DammeGeert van LooAndy Wullaert

A1 Journal Article in CELL DEATH & DISEASE

2023