Research Explorer

Project

PAOx for Antibody-Drug Conjugates
Acronym
PAOx for ADCs
Code
F2016/IOF-CONTT/004
Duration
15 April 2016 → 14 April 2017
Funding
Regional and community funding: Industrial Research Fund
Research disciplines
  • Natural sciences
    • Organic chemistry
Keywords
PAOx
 
Project description
 

To develop in vitro PoC for poly(2-oxazoline) anitobody drug conjugates (PAOx-ADCs). The in vitro efficacy of a trastuzumab based PAOx-ADC loaded with doxorubicine will be evaluated against cell lines expressing HER2 antigen targets aiming for equal or higher efficacy compared to Kadcyla as clinically used benchmark