Research Explorer

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Project

Protein-protein interactions: from bench to bedside

Outputs and Outcomes

Code

01M00609

Duration

01 January 2009 → 31 December 2020

Funding

Regional and community funding: Special Research Fund

Promotor

Jan Tavernier

Research disciplines

Medical and health sciences
- Endocrinology

Keywords

MAPPIT protein-protein interactions interactomics crystallography medicinal chemistry signaling pathways

Project description

Protein-protein interactions (PPI's) are at the heart of cellular function. In our Methusalem consortium, we will apply several techniques including MAPPIT and protein crystallography in order to obtain a deeper insight into the role of PPI's at several levels: from large-scale interactome mapping and signalling pathways down to the molecular details of designated protein interaction pairs. This program incorporates the interaction between small molecules and proteins as well.

English

Dutch

English

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