Code
01CD8322
Looptijd
16-01-2023 → 15-10-2023
Financiering
Regional and community funding: Special Research Fund
Promotor
Onderzoeksdisciplines
-
Medical and health sciences
- Cardiology
Trefwoorden
Aritmogene cardiomyopathie
geïnduceerde pluripotente stamcellen
geconstrueerd hartweefsel
ziektemodellering
Projectomschrijving
Arrhythmogenic cardiomyopathy is a rare heritable heart muscle disease, characterized by progressive substitution of myocardium by fibro-fatty tissue. Molecular mechanisms underlying this disease remain elusive. In the PhD project of Laurens Léger, engineered heart tissues from patientspecific induced pluripotent stem cells are generated to elucidate early molecular mechanisms.