Research Explorer

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Project

Gene cluster identification and microbial biosynthesis of iminosugars (IMINOGENE)

Outputs and Outcomes

Publications

Natural and Synthetic Iminosugars Reduce Colorectal Cancer Cell Viability and Alter Bioenergetic Metabolism via Specific Mechanisms

Thomas MontebugnoliCharlotte GrootaertAlessandra BordoniAndreja RajkovicSofie De MaeseneireJohn Van CampMaarten De Mol

Evaluation of iminosugars’ glycomimetic and cytotoxicity effects on healthy and carcinogenic colorectal cells

Cristina AimoneElien AlderweireldtCharlotte GrootaertAndreja RajkovicMaarten De MolJohn Van Camp

Iminosugar effects on (cancer) cell lines, and their biomanufacturing

Marco FernandezThomas MontebugnoliCharlotte GrootaertAndreja RajkovicElien AlderweireldtJeltien RombautSofie De MaeseneireJohn Van CampMaarten De Mol

From genetic resources to bioprocess development : tools and technologies to help you create a robust microbial fermentation process

Maarten De MolAnne-Sofie De RopJeltien RombautThomas WillemsThomas MontebugnoliCharlotte GrootaertMarieke MispelaereElien AlderweireldtWim HectorsNico SnoeckCedric HermansSofie De MaeseneireAndreja RajkovicPaco HulpiauWim SoetaertJohn Van Camp et al.

MariClus : your one-stop platform for information on marine natural products, their gene clusters and producing organisms

Maarten De MolJeltien RombautAnne-Sofie De RopThomas WillemsWim HectorsNico SnoeckMarieke MispelaereCedric HermansSofie De MaeseneirePaco HulpiauWim Soetaert et al.

Food iminosugars and related synthetic derivatives shift energy metabolism and induce structural changes in colon cancer cell lines

Thomas MontebugnoliCharlotte GrootaertAlessandra BordoniAndreja RajkovicElien AlderweireldtJeltien RombautSofie De MaeseneireJohn Van CampMaarten De Mol

A1 Journal Article in FOODS

Novel iminosugar enzymes and products through metagenomics

Anne-Sofie De RopMaarten De MolSofie De MaeseneireInari WillemsMarieke MispelaerePaco HulpiauWim Soetaert

MariClus : your one-stop platform for information on marine natural products, their gene clusters and producing organisms

Maarten De MolCedric HermansMarieke MispelaereAnne-Sofie De RopJeltien RombautTesneem NusayrRebecca CreamerSofie De MaeseneireWim SoetaertPaco Hulpiau

Whole genome-based comparative analysis of the genus Streptomyces reveals many misclassifications

Marieke MispelaereAnne-Sofie De RopCedric HermansSofie De MaeseneireWim SoetaertMaarten De MolPaco Hulpiau

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An exploratory in silico comparison of open-source codon harmonization tools

Thomas WillemsWim HectorsJeltien RombautAnne-Sofie De RopStijn GoegebeurTom DelmulleMaarten De MolSofie De MaeseneireWim Soetaert

A1 Journal Article in MICROBIAL CELL FACTORIES

MariClus : your one-stop platform for information on marine natural products, their gene clusters and producing organisms

Cedric HermansMaarten De MolMarieke MispelaereAnne-Sofie De RopJeltien RombautTesneem NusayrRebecca CreamerSofie De MaeseneireWim SoetaertPaco Hulpiau

A1 Journal Article in MARINE DRUGS

Discovery and structure elucidation of novel alkaloids from marine actinobacteria

Jeltien RombautAnne-Sofie De RopThomas WillemsMarilyn De GraeveLynn VanhaeckePaco HulpiauSofie De MaeseneireMaarten De MolWim Soetaert

Novel alkaloids from marine actinobacteria : discovery and characterization

Anne-Sofie De RopJeltien RombautThomas WillemsMarilyn De GraeveLynn VanhaeckePaco HulpiauSofie De MaeseneireMaarten De MolWim Soetaert

A1 Journal Article in MARINE DRUGS