Project

Omics for PATHogenic Yeasts: Host pathogen interactions in Candida vaginitis as established with dual RNA sequencing

Acroniem
OPATHY
Code
01IT0718
Looptijd
14-03-2019 → 13-09-2019
Financiering
Regional and community funding: Special Research Fund
Onderzoeksdisciplines
  • Natural sciences
    • Mycology
    • Genomics
    • Proteomics
    • Transcriptomics
  • Medical and health sciences
    • Inflammation
    • Clinical microbiology
    • Mycology
    • Immunogenetics
    • Mycology
    • Clinical genetics and molecular diagnostics
    • Clinical microbiology
    • Mycology
Trefwoorden
Pathogene gisten volgende generatie sequencing proteomics omica diagnostische weerstand gastheer pathogeen
 
Projectomschrijving

The aim of this doctoral research is to elucidate the host-pathogen interactions in vaginal samples of women with acute and chronic Candida vaginitis as compared to women without vaginitis. For this purpose, we planned to carry out dual RNA-sequencing to detect differently expressed genes from Candida and from the host simultaneously, in clinical samples, i.e., in vaginal swabs of women with
acute and chronic candidiasis and in women that are carriers of Candida without infection.