A novel function of urokinase plasminogen activator as a ligand for natural killer receptors: exploration of receptor biology and implications in tumor immunity

01 January 2007 → 31 December 2010
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Immunology
intestinal epithelial cells NK cells
Project description

This project is a fundamental study of the regulation of innate lymphocytes, including natural killer cells as well as 'innate' T lymphocytes located in the epidermis and intestinal epithelium. The effect of urokinase plaminogen activator on the cytotoxicity and cytokine production of these innate lymphocytes will be studied.