Acroniem
3E00411
Code
3E004111
Looptijd
01-10-2011 → 30-09-2014
Financiering
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Onderzoeksdisciplines
-
Natural sciences
- Genetics
- Systems biology
-
Medical and health sciences
- Cardiac and vascular medicine
- Laboratory medicine
- Molecular and cell biology
- Palliative care and end-of-life care
- Regenerative medicine
- Other basic sciences
- Cardiac and vascular medicine
- Laboratory medicine
- Palliative care and end-of-life care
- Regenerative medicine
- Other clinical sciences
- Other health sciences
- Nursing
- Other paramedical sciences
- Cardiac and vascular medicine
- Laboratory medicine
- Molecular and cell biology
- Palliative care and end-of-life care
- Regenerative medicine
- Other translational sciences
- Other medical and health sciences
Trefwoorden
arteriële tortuositeitssyndroom
bindweefselziekten
familiale thoracale aneurysmata
cerebrale aneurysmata
genetica
Projectomschrijving
This project assesses proper vascular development and maintenance through the study of inherited connective tissue diseases. We will (1) unravel the molecular basis by wich mutations un GLUT10 cause aberrant vascular development in a mouse model for arterial tortuosity syndrome; (2) search fot new genetic defects causing familial aortic aneurysms; (3) clinically and molecularly characterize patiens with cerebral aneurysms.