Project

The working mechanism of a new class of adjuvant, the Layered Double Hydroxide (LDH) family.

Code
3F011712
Looptijd
01-10-2012 → 15-11-2015
Financiering
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Onderzoeksdisciplines
  • Medical and health sciences
    • Immunology
    • Immunology
    • Immunology
Trefwoorden
vaccinatie adjuvant cellulair en moleculair werkingsmechanisme layered double hydroxide
 
Projectomschrijving

This interdisciplinary project combines key aspects of chemistry and immunology to predict which members of a new class of adjuvants, the Layered double hydroxide family (LDH), induce a better cellular and/or humoral immune response than the common used adjuvant alum. Besides, we will unravel their cellular and molecular mechanism of action and their applicability in an influenza infection model.