Code
01D28520
Duration
01 November 2020 → 31 October 2024
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Bioinformatics data integration and network biology
Keywords
gene regulation
transcriptomics
epigenomics
metabolomics
clustering
dimensionality reduction
network inference
machine learning
benchmarking
Project description
First, we will conduct a benchmarking of computational methods for multi-omics data integration. Next, we will develop an improved methodology for multi-omics data integration in the context of regulatory networks to gain in-depth mechanistic insights. Finally, we will apply our methodology to neuro-inflammatory disorders and cancer to identify novel regulators such as regulatory metabolites.