Project

Regulation of placental development in horses: reciprocal parental control of angiogenesis in equine placenta and abnormal placental development.

Duration
01 November 2020 → Ongoing
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Medical and health sciences
    • Organ physiology
  • Agricultural and food sciences
    • Veterinary embryology
    • Veterinary genetics
    • Veterinary physiology, pathophysiology and biochemistry
    • Veterinary reproduction and obstetrics
Keywords
horse gestation placental angiogenesis in the mare parental gene expression imprinting chorioallantois physiology/ pathophysiology
 
Project description

Pathological conditions of the placenta have significant effects on the health of fetus and mother. In mares, pathological conditions, such as fetal growth retardation, placentitis and hydrops, are associated with compromised placental vascularization. Using high-throughput data, we aim to gain insight into the regulatory mechanisms of vascularization in the normal and abnormal placenta and provide fundamental information on placental development.